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The map label for this gene is lepB [H]

Identifier: 189424073

GI number: 189424073

Start: 1045875

End: 1046447

Strand: Reverse

Name: lepB [H]

Synonym: Glov_1007

Alternate gene names: 189424073

Gene position: 1046447-1045875 (Counterclockwise)

Preceding gene: 189424074

Following gene: 189424072

Centisome position: 26.71

GC content: 43.28

Gene sequence:

>573_bases
ATGATCAACAAGTTTATTTTGATTAGCGCAATTTTGCTGTTAGGTATCGCGTCTGTAGCAGGGGCATTGTATATCAGAGA
AAATGTTGTGAAGGCGTACAAGATTCCAGCAGCAAGTATGGAGCCTACCCTGCTCGTTGGAGATCATATTTTGGTTGACC
GTAGCAAGGCTGCACGGCCCCCCAGGCGAGGAGACCTGATAGTTTTCAAATATCCTGAAGATCCGTCAAAAGATTTCGTA
AAACGTGTTGTTGCTGTAGCCGGTGATACGGTTGAGATAAAAGACAAAATTCTGCTTATCAATGGAAAAGCCGTTAATGA
GCCTTACGTTGTGCATAAGGAAAAAGAGATATTCCCGGCAACTGAAAATCCACGTGACAATCTTCCGCTCCTAAAAATTG
CAGCTGCTTCCTTTTTTGTAATGGGTGACAATCGCGACAGAAGCTATGACAGTCGTTTTTGGGGCACTGTTTCTAAAGAC
AAAATCAAAGGGACGGTCAAATCAATCTATTGGTCATGGGATAGAACCACTATGTCAGTTCGCTGGGACAGAATTGGTAA
GGCTGTTCAATGA

Upstream 100 bases:

>100_bases
TTGGACAATTGCCAGTCAACAACTGTTAACCAGCGGCACGACCTGCCCGAAAACCCGGCAGGTCAAAGCCATGCCAGTTA
AACCCTAGGGGGTCAAACAG

Downstream 100 bases:

>100_bases
CATCCACTACGCAGCCATCAAAAGCGGCTGTACCTGTTGTACCCTCTACTCGTTGTGCGGTTGCAAGCCATGAGACACAT
GTTTTTAGCCCTCCTCCTGT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MINKFILISAILLLGIASVAGALYIRENVVKAYKIPAASMEPTLLVGDHILVDRSKAARPPRRGDLIVFKYPEDPSKDFV
KRVVAVAGDTVEIKDKILLINGKAVNEPYVVHKEKEIFPATENPRDNLPLLKIAAASFFVMGDNRDRSYDSRFWGTVSKD
KIKGTVKSIYWSWDRTTMSVRWDRIGKAVQ

Sequences:

>Translated_190_residues
MINKFILISAILLLGIASVAGALYIRENVVKAYKIPAASMEPTLLVGDHILVDRSKAARPPRRGDLIVFKYPEDPSKDFV
KRVVAVAGDTVEIKDKILLINGKAVNEPYVVHKEKEIFPATENPRDNLPLLKIAAASFFVMGDNRDRSYDSRFWGTVSKD
KIKGTVKSIYWSWDRTTMSVRWDRIGKAVQ
>Mature_190_residues
MINKFILISAILLLGIASVAGALYIRENVVKAYKIPAASMEPTLLVGDHILVDRSKAARPPRRGDLIVFKYPEDPSKDFV
KRVVAVAGDTVEIKDKILLINGKAVNEPYVVHKEKEIFPATENPRDNLPLLKIAAASFFVMGDNRDRSYDSRFWGTVSKD
KIKGTVKSIYWSWDRTTMSVRWDRIGKAVQ

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=86, Percent_Identity=40.6976744186046, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21374; Mature: 21374

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKFILISAILLLGIASVAGALYIRENVVKAYKIPAASMEPTLLVGDHILVDRSKAARP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEECHHHCCC
PRRGDLIVFKYPEDPSKDFVKRVVAVAGDTVEIKDKILLINGKAVNEPYVVHKEKEIFPA
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCEEEECCCCCCCC
TENPRDNLPLLKIAAASFFVMGDNRDRSYDSRFWGTVSKDKIKGTVKSIYWSWDRTTMSV
CCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHCCCCCHHHHHHEEEHEEEECCCEEEEE
RWDRIGKAVQ
EHHHHCCCCC
>Mature Secondary Structure
MINKFILISAILLLGIASVAGALYIRENVVKAYKIPAASMEPTLLVGDHILVDRSKAARP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEECHHHCCC
PRRGDLIVFKYPEDPSKDFVKRVVAVAGDTVEIKDKILLINGKAVNEPYVVHKEKEIFPA
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCEEEECCCCCCCC
TENPRDNLPLLKIAAASFFVMGDNRDRSYDSRFWGTVSKDKIKGTVKSIYWSWDRTTMSV
CCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHCCCCCHHHHHHEEEHEEEECCCEEEEE
RWDRIGKAVQ
EHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]