Click here to switch to the map view.

The map label for this gene is mreB [H]

Identifier: 189424046

GI number: 189424046

Start: 1018753

End: 1019796

Strand: Reverse

Name: mreB [H]

Synonym: Glov_0980

Alternate gene names: 189424046

Gene position: 1019796-1018753 (Counterclockwise)

Preceding gene: 189424050

Following gene: 189424045

Centisome position: 26.03

GC content: 58.91

Gene sequence:

>1044_bases
ATGTTCAAGATATTCGACTCACTGTTCGGGATGTTTTCCAACGATCTGGCCATCGACCTTGGCACCGCCAACACCCTGGT
CTATCTGAAGGGTAAGGGGATCGTCGTCCGTGAGCCTTCGGTGGTTGCCGTCCAGAAAATGCCCACCGGCCAGCAGAAGG
TGCTGAAGGTCGGGATGGAGGCCAAGCAGATGCTGGGCCGTACTCCCGGTTCCATCACCGCCATCCGCCCGATGAAGGAT
GGGGTTATCGCCGACTTTGACATCACCGAAGAGATGCTGCGCTACTTCATCCACAAGGTACACAACCGCAAGACCCTGGT
CCGTCCCCGGATCGTGATCTGCGTCCCCTCCGGCATCACCCAGGTGGAAAAACGGGCGGTCAAGGAATCGGCCGAGTCTG
CCGGTGCCCGCGAGGTCTACCTGATTGAAGAACCGATGGCGGCCGCCATCGGAGCCGGCCTGCCGATCACCGAGGCAAGC
GGCAACATGATCGTTGATATCGGCGGCGGCACCACTGAAGTTGCCGTGATCTCCCTGGCCGGCATCGTCTACTCCCAGTC
GACCCGGATGGGTGGTGACAAGATGGATGAGGCGATTGTCCAGTACATCAAGCGCAAGTACAACCTGCAGATCGGTGAAC
GGATGGCGGAAGCGATCAAGATCGAGATCGGCGAAGCCTACCCCGGCCCTGAAGTACTGACCATGGAGGTCAAAGGGCGC
GACCTGGTATCAGGTATCCCCAAGACGATAGAGATCAACTCTGACGAAATCCGTGATGCCCTCAAGGAAGCGGTTAACGC
CATTGTGGATACCGTCCGTCAATGCCTTGAGCGTACCCCGCCCGAACTGGCTGCCGATATCGTAGACAAGGGAATCTTCC
TGGCCGGTGGCGGCGCCGGCCTGCGCAATCTGGACCTGCTGCTGCGCGAGATCACCAAGGTGCCGGTACTGATTGCAGAA
AACCCGCTGGACTGTGTTGTTCTGGGCTCCGGCAAGGTACTGGATGAGCTGAACCTGCTCAAGCGCGTTGCCGTTACCTC
ATAA

Upstream 100 bases:

>100_bases
AGCACGCTGCTGCCGCAGACGGCATCTGTTTTCCCCCTTGCATTAACCTACCTATTCTGCTAGTTTTTTTAGTCCATTTT
TCCTGAAAGGAATTCCACCC

Downstream 100 bases:

>100_bases
CAGAGCCTTTTCGTCCTGAAAGTACTACGAATAAAACAATCTCAAGGGGTGGGTTATGCCCACCCTTTCTAGTTAGTGCC
TATGACCGCTCCCACTTTTG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFKIFDSLFGMFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKMPTGQQKVLKVGMEAKQMLGRTPGSITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVYSQSTRMGGDKMDEAIVQYIKRKYNLQIGERMAEAIKIEIGEAYPGPEVLTMEVKGR
DLVSGIPKTIEINSDEIRDALKEAVNAIVDTVRQCLERTPPELAADIVDKGIFLAGGGAGLRNLDLLLREITKVPVLIAE
NPLDCVVLGSGKVLDELNLLKRVAVTS

Sequences:

>Translated_347_residues
MFKIFDSLFGMFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKMPTGQQKVLKVGMEAKQMLGRTPGSITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVYSQSTRMGGDKMDEAIVQYIKRKYNLQIGERMAEAIKIEIGEAYPGPEVLTMEVKGR
DLVSGIPKTIEINSDEIRDALKEAVNAIVDTVRQCLERTPPELAADIVDKGIFLAGGGAGLRNLDLLLREITKVPVLIAE
NPLDCVVLGSGKVLDELNLLKRVAVTS
>Mature_347_residues
MFKIFDSLFGMFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKMPTGQQKVLKVGMEAKQMLGRTPGSITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVYSQSTRMGGDKMDEAIVQYIKRKYNLQIGERMAEAIKIEIGEAYPGPEVLTMEVKGR
DLVSGIPKTIEINSDEIRDALKEAVNAIVDTVRQCLERTPPELAADIVDKGIFLAGGGAGLRNLDLLLREITKVPVLIAE
NPLDCVVLGSGKVLDELNLLKRVAVTS

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=341, Percent_Identity=60.9970674486804, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17534771, Length=167, Percent_Identity=29.940119760479, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17507981, Length=245, Percent_Identity=26.9387755102041, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37500; Mature: 37500

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKIFDSLFGMFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKMPTGQQKVLKVGME
CHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEECCCEEEEECCCCCHHHHHHHHHH
AKQMLGRTPGSITAIRPMKDGVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGIT
HHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCHH
QVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEASGNMIVDIGGGTTEVAVISLA
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCHHHHHHHHH
GIVYSQSTRMGGDKMDEAIVQYIKRKYNLQIGERMAEAIKIEIGEAYPGPEVLTMEVKGR
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCEEEEEECCC
DLVSGIPKTIEINSDEIRDALKEAVNAIVDTVRQCLERTPPELAADIVDKGIFLAGGGAG
HHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCC
LRNLDLLLREITKVPVLIAENPLDCVVLGSGKVLDELNLLKRVAVTS
HHHHHHHHHHHHHCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKIFDSLFGMFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKMPTGQQKVLKVGME
CHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEECCCEEEEECCCCCHHHHHHHHHH
AKQMLGRTPGSITAIRPMKDGVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGIT
HHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCHH
QVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEASGNMIVDIGGGTTEVAVISLA
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCHHHHHHHHH
GIVYSQSTRMGGDKMDEAIVQYIKRKYNLQIGERMAEAIKIEIGEAYPGPEVLTMEVKGR
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCEEEEEECCC
DLVSGIPKTIEINSDEIRDALKEAVNAIVDTVRQCLERTPPELAADIVDKGIFLAGGGAG
HHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCC
LRNLDLLLREITKVPVLIAENPLDCVVLGSGKVLDELNLLKRVAVTS
HHHHHHHHHHHHHCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]