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The map label for this gene is moaC

Identifier: 189423994

GI number: 189423994

Start: 957655

End: 958137

Strand: Reverse

Name: moaC

Synonym: Glov_0928

Alternate gene names: 189423994

Gene position: 958137-957655 (Counterclockwise)

Preceding gene: 189423995

Following gene: 189423993

Centisome position: 24.46

GC content: 58.8

Gene sequence:

>483_bases
ATGAACTTTAACCACTTTGATGAACAGGGCCATGCGGTCATGGTGGATGTCAGCAGCAAGCAGGAGACCATGCGGACCGC
CACGGCAGCTGCCGATGTGATCATGTCTGCAGAACTGCTGGCCGCCATTGCCCGGAAGAGCGTATCCAAGGGGGATGTGC
TGGGGGTGGCACGTCTGGCCGGCATCATGGCAGCCAAGAAGACCGACGACCTGATTCCGCTTTCCCATCCGCTTTCCCTG
CACTCGGTCTCAATCGAGTTTGATCAGGACCCGGCAGCCTGCAGGATTCAGGCACGCTGCACCGTACGGGCCTTTGAACG
GACCGGGGTTGAGATGGAGGCGATGACCGGCGCAGCGGTTGCCGCCCTGACCATCTACGACATGTGCAAAGGGACCGACA
AATCCATCAGCATTGCAAACATCCGGCTGCTCTATAAAGAAGGTGGTAAAAGCGGCCTGTATCGCCGGGAGGAGGCAGCA
TGA

Upstream 100 bases:

>100_bases
TGAACCGTATCGCAGGGACGATCTTTGCCGCACTGGCCGTCAAACTGGTGACAGCCCAGCGCTGACGAATCAAAAAACTG
AAACAGAAGGAGTCATACAG

Downstream 100 bases:

>100_bases
GGGCGGCCATTCTGACCTTGAGCGACAAAGGGGCACGGGGTGAGCGGGTCGATGCCAGCGGCCCTGCCCTGAGCGCCTGG
CTGGCTGAGCGGGGGGTAAC

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MNFNHFDEQGHAVMVDVSSKQETMRTATAAADVIMSAELLAAIARKSVSKGDVLGVARLAGIMAAKKTDDLIPLSHPLSL
HSVSIEFDQDPAACRIQARCTVRAFERTGVEMEAMTGAAVAALTIYDMCKGTDKSISIANIRLLYKEGGKSGLYRREEAA

Sequences:

>Translated_160_residues
MNFNHFDEQGHAVMVDVSSKQETMRTATAAADVIMSAELLAAIARKSVSKGDVLGVARLAGIMAAKKTDDLIPLSHPLSL
HSVSIEFDQDPAACRIQARCTVRAFERTGVEMEAMTGAAVAALTIYDMCKGTDKSISIANIRLLYKEGGKSGLYRREEAA
>Mature_160_residues
MNFNHFDEQGHAVMVDVSSKQETMRTATAAADVIMSAELLAAIARKSVSKGDVLGVARLAGIMAAKKTDDLIPLSHPLSL
HSVSIEFDQDPAACRIQARCTVRAFERTGVEMEAMTGAAVAALTIYDMCKGTDKSISIANIRLLYKEGGKSGLYRREEAA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=50.6410256410256, Blast_Score=146, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.2818791946309, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28574490, Length=156, Percent_Identity=48.7179487179487, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=49.3055555555556, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_GEOLS (B3E5I0)

Other databases:

- EMBL:   CP001089
- RefSeq:   YP_001951171.1
- ProteinModelPortal:   B3E5I0
- SMR:   B3E5I0
- GeneID:   6367138
- GenomeReviews:   CP001089_GR
- KEGG:   glo:Glov_0928
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   CLSK828946
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17190; Mature: 17190

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNHFDEQGHAVMVDVSSKQETMRTATAAADVIMSAELLAAIARKSVSKGDVLGVARLA
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GIMAAKKTDDLIPLSHPLSLHSVSIEFDQDPAACRIQARCTVRAFERTGVEMEAMTGAAV
HHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEEEEEEHHHCCCEEEHHCCHHH
AALTIYDMCKGTDKSISIANIRLLYKEGGKSGLYRREEAA
HHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNFNHFDEQGHAVMVDVSSKQETMRTATAAADVIMSAELLAAIARKSVSKGDVLGVARLA
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GIMAAKKTDDLIPLSHPLSLHSVSIEFDQDPAACRIQARCTVRAFERTGVEMEAMTGAAV
HHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEEEEEEHHHCCCEEEHHCCHHH
AALTIYDMCKGTDKSISIANIRLLYKEGGKSGLYRREEAA
HHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA