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The map label for this gene is resE [H]

Identifier: 189423938

GI number: 189423938

Start: 896183

End: 897259

Strand: Reverse

Name: resE [H]

Synonym: Glov_0871

Alternate gene names: 189423938

Gene position: 897259-896183 (Counterclockwise)

Preceding gene: 189423939

Following gene: 189423937

Centisome position: 22.9

GC content: 57.47

Gene sequence:

>1077_bases
ATGGGCATCAAACAACTTCTGATTGTCGCAAACGACACCAGCGCCGCCCAACTGGCATTCCAGCTGCTCGAAGCAGGGCC
GTACCAGCTGCACCTGGCCGAAACCTGCGAAGCGGCCCGCAGCATACTTACGCGGCAACGGCTGGATGCCATCCTGCTCG
GTTCTCCCCCCTACCAGCACTGCCTTCCCTCCCTGGAGCATCTGCAGGAATCCGGCAACGATCCGGCGGTAATTGCCCTG
CTGGATGCCAATGAGCAGGAGCGCTATCTGGACTGTCACAAACAGGGTGCGCTGGATTGCCTGATGGCCCCGTTCAGTGT
TGAGCGGCTGGTAAAGAGTATAGAACGCTGCCTGGCAATCAAGTCACTGGAGCGGGAAAAGCGGGACTTTATCTCCATGC
TCTCCCATGATCTGAAAAACCCGCTTACTGCGGCGATCGGCTCAATTGACCTGGTCAGAGAAAAGCGGCTCGGCCCGCTT
AACCGTGAACAGACCAGTTACCTGCTTTCAGCCATTGAGAGCTGTAATGAAGTGGTGGCCATGATCGACAACCTGCTGGA
CCTCCACCGTCTTGAGGCCGGCAAGATCGCCTTTCACAAAACACCGGTCAACCTGTCAGAGCTGGCACAACAGGTAGTCG
CAGGATTTCGCGGCATGATCAAACATGCCCAGATCCACCTGCAGACGCAGCTGGAAGATGATCTGCCCCTGCTGAATCTG
GACAGGAACAAATTCTCCCGGGTGATCGCCAACCTGCTAGCCAATGCCGTCAAATTCACCCCCTGCGGCGGAGAAATCAG
CGTGCGCTGTTACTGCGGCGTGTCGGCCGACTCTGATGTGGCGGTCATGCTCAGCATCACAGATACCGGTAACGGCATTG
CCACGGTCGAACTGCCGATGATCTTTGACCGTTTTGTCCAGGCCCGCAACCAGACCGGACGGGGCAGTGGAGGCAGCGGG
CTCGGCCTGGCATTCTGCAAAATGGTAACTGAAGCGCATAACGGCACCATCACTACTGACAGCCGGGAAGGTGTCGGCAG
CGAATTCACCATTACCCTGCCACTGCCGGAACAATAA

Upstream 100 bases:

>100_bases
ATCGTGAACGGCAGCTATCGAAACATAAAGATCACCACTCCGGAAGACCTGGTGCTTGCCGAGGCGTTTCTAAACCAGAC
AGCTGGAGGCCGGCCATAAC

Downstream 100 bases:

>100_bases
CGGAGACTGGCTATGACTCAACGTTTTCTGCTCACCCTCGCTTTGCTGGCAACCATGGTATTTTGTTCAGGTACCGCCTC
CGCTGCCACGATTGATTTAA

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MGIKQLLIVANDTSAAQLAFQLLEAGPYQLHLAETCEAARSILTRQRLDAILLGSPPYQHCLPSLEHLQESGNDPAVIAL
LDANEQERYLDCHKQGALDCLMAPFSVERLVKSIERCLAIKSLEREKRDFISMLSHDLKNPLTAAIGSIDLVREKRLGPL
NREQTSYLLSAIESCNEVVAMIDNLLDLHRLEAGKIAFHKTPVNLSELAQQVVAGFRGMIKHAQIHLQTQLEDDLPLLNL
DRNKFSRVIANLLANAVKFTPCGGEISVRCYCGVSADSDVAVMLSITDTGNGIATVELPMIFDRFVQARNQTGRGSGGSG
LGLAFCKMVTEAHNGTITTDSREGVGSEFTITLPLPEQ

Sequences:

>Translated_358_residues
MGIKQLLIVANDTSAAQLAFQLLEAGPYQLHLAETCEAARSILTRQRLDAILLGSPPYQHCLPSLEHLQESGNDPAVIAL
LDANEQERYLDCHKQGALDCLMAPFSVERLVKSIERCLAIKSLEREKRDFISMLSHDLKNPLTAAIGSIDLVREKRLGPL
NREQTSYLLSAIESCNEVVAMIDNLLDLHRLEAGKIAFHKTPVNLSELAQQVVAGFRGMIKHAQIHLQTQLEDDLPLLNL
DRNKFSRVIANLLANAVKFTPCGGEISVRCYCGVSADSDVAVMLSITDTGNGIATVELPMIFDRFVQARNQTGRGSGGSG
LGLAFCKMVTEAHNGTITTDSREGVGSEFTITLPLPEQ
>Mature_357_residues
GIKQLLIVANDTSAAQLAFQLLEAGPYQLHLAETCEAARSILTRQRLDAILLGSPPYQHCLPSLEHLQESGNDPAVIALL
DANEQERYLDCHKQGALDCLMAPFSVERLVKSIERCLAIKSLEREKRDFISMLSHDLKNPLTAAIGSIDLVREKRLGPLN
REQTSYLLSAIESCNEVVAMIDNLLDLHRLEAGKIAFHKTPVNLSELAQQVVAGFRGMIKHAQIHLQTQLEDDLPLLNLD
RNKFSRVIANLLANAVKFTPCGGEISVRCYCGVSADSDVAVMLSITDTGNGIATVELPMIFDRFVQARNQTGRGSGGSGL
GLAFCKMVTEAHNGTITTDSREGVGSEFTITLPLPEQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=31.2757201646091, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.1304347826087, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=27.9835390946502, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789149, Length=250, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=251, Percent_Identity=29.8804780876494, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786912, Length=288, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=29.5652173913043, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786783, Length=265, Percent_Identity=28.3018867924528, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786600, Length=257, Percent_Identity=25.6809338521401, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=29.1845493562232, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=274, Percent_Identity=26.2773722627737, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=28.0334728033473, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=30.8411214953271, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=242, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=25.6410256410256, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39113; Mature: 38982

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKQLLIVANDTSAAQLAFQLLEAGPYQLHLAETCEAARSILTRQRLDAILLGSPPYQH
CCCCEEEEEECCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCEEEECCCCHHH
CLPSLEHLQESGNDPAVIALLDANEQERYLDCHKQGALDCLMAPFSVERLVKSIERCLAI
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
KSLEREKRDFISMLSHDLKNPLTAAIGSIDLVREKRLGPLNREQTSYLLSAIESCNEVVA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
MIDNLLDLHRLEAGKIAFHKTPVNLSELAQQVVAGFRGMIKHAQIHLQTQLEDDLPLLNL
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEC
DRNKFSRVIANLLANAVKFTPCGGEISVRCYCGVSADSDVAVMLSITDTGNGIATVELPM
CHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEHHH
IFDRFVQARNQTGRGSGGSGLGLAFCKMVTEAHNGTITTDSREGVGSEFTITLPLPEQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
GIKQLLIVANDTSAAQLAFQLLEAGPYQLHLAETCEAARSILTRQRLDAILLGSPPYQH
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCEEEECCCCHHH
CLPSLEHLQESGNDPAVIALLDANEQERYLDCHKQGALDCLMAPFSVERLVKSIERCLAI
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
KSLEREKRDFISMLSHDLKNPLTAAIGSIDLVREKRLGPLNREQTSYLLSAIESCNEVVA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
MIDNLLDLHRLEAGKIAFHKTPVNLSELAQQVVAGFRGMIKHAQIHLQTQLEDDLPLLNL
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEC
DRNKFSRVIANLLANAVKFTPCGGEISVRCYCGVSADSDVAVMLSITDTGNGIATVELPM
CHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEHHH
IFDRFVQARNQTGRGSGGSGLGLAFCKMVTEAHNGTITTDSREGVGSEFTITLPLPEQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]