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The map label for this gene is gldA [H]

Identifier: 189423781

GI number: 189423781

Start: 727577

End: 728668

Strand: Reverse

Name: gldA [H]

Synonym: Glov_0712

Alternate gene names: 189423781

Gene position: 728668-727577 (Counterclockwise)

Preceding gene: 189423782

Following gene: 189423780

Centisome position: 18.6

GC content: 61.63

Gene sequence:

>1092_bases
ATGCTGAACAAAGCGATGTTCCCCGGAAAATACCTGCAAGGCGCAGCGGCTCTGAACGAGTTGCCGGCCCTGGTCCAACT
GTTTGGCAGACAGGGCCTGATCCTGGCTTCGGCAACGGCCTGCGACAGGATTCTTCCTGACAGCGGCATCGACCTGAAGC
GACATAATCTGTCGCTCGAACGTTTTAACGGCGAGTGTTGCGAACAAGAGCTGACCCGCCTGGCAGCCGTCATTAAAGCA
AAGCAGGTGGATGTCCTGGTGGGGATGGGTGGCGGCAAGGCCATTGACACGGCAAAGATTGCAGCCGACCGTGCCGGCAT
CCCGGTCATCATCGTACCCACCATCGCCTCCACCGACGCTCCCTGCAGCGGCTGCGCCGTGCTGTATTCAGCACAGGGTG
TCTTTGAATCGGTTTACTACCAGCGCTCAAACCCGGCAGCTGTGCTGGTGGACTCCGCCATCATCGTCCGGGCGCCGGTC
CGCTTTCTGGTGGCCGGCATGGGAGATGCGCTGGCAACCTGGTTTGAGGCCCGTTCCTGCCATGCCACCCGTTCGGCAAA
CGCCTGCGGCGGTCTCAGTACCCTGACCGGCCTTAACCTGGCCCGGCTCTGCTACGATACCCTGCTGCGCTACGGCGCGG
CCGCCAAGACCGCAGCGGAGCAACAGATCATCACCCCGGCCCTGGAGCATATCATTGAGGCCAACACCCTGCTTTCCGGC
ATCGGCTTTGAAAGCGGCGGACTGGCCAGCGCCCATTCCATCCACAACGGACTGACCGCATTGGCAGAAACCCATGCCTT
CTACCACGGTGAGAAAGTGGCCTTTGGTCTGTTGGCCGGTCTGCAGTTGATCGACGCACCGCCGGAAGAGATCAACGAAG
TCTACAGGTTCTGTGAGGCAGTGGGGTTGCCCACCACCCTGGCGGCTGTCGGCCTGGCCGGATGCGGACGCGATCGCCTG
CTGCAGGTGGCACAGAAGGCCTGCGCCCCGGAGGAGTGCATTCACCATGAGGCAGGTAGCATCACGCCTGACAAGGTGCT
TAACGCCATGCTGGCGGCAGATGCGATCGGCACACGCAGAAAATCAGTGTGA

Upstream 100 bases:

>100_bases
GCGCTGTGAAGAAATAAACAGGGTGACGGTGACCCTGAAGCAGGGCTGATCGAGGCGGCGGCATACGCCTATTATACGAC
GTCTACCAAGGAGAAAGCGG

Downstream 100 bases:

>100_bases
GAGACAGGTCAGGATGCCGGAGCAAGGTGCCGCTAAAGCTGACGGCAGCGACTTATGGTTGACTGACCCTGTCACGCCCA
GCTTGCACGAAACACGGTAC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: GDH; GLDH [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLNKAMFPGKYLQGAAALNELPALVQLFGRQGLILASATACDRILPDSGIDLKRHNLSLERFNGECCEQELTRLAAVIKA
KQVDVLVGMGGGKAIDTAKIAADRAGIPVIIVPTIASTDAPCSGCAVLYSAQGVFESVYYQRSNPAAVLVDSAIIVRAPV
RFLVAGMGDALATWFEARSCHATRSANACGGLSTLTGLNLARLCYDTLLRYGAAAKTAAEQQIITPALEHIIEANTLLSG
IGFESGGLASAHSIHNGLTALAETHAFYHGEKVAFGLLAGLQLIDAPPEEINEVYRFCEAVGLPTTLAAVGLAGCGRDRL
LQVAQKACAPEECIHHEAGSITPDKVLNAMLAADAIGTRRKSV

Sequences:

>Translated_363_residues
MLNKAMFPGKYLQGAAALNELPALVQLFGRQGLILASATACDRILPDSGIDLKRHNLSLERFNGECCEQELTRLAAVIKA
KQVDVLVGMGGGKAIDTAKIAADRAGIPVIIVPTIASTDAPCSGCAVLYSAQGVFESVYYQRSNPAAVLVDSAIIVRAPV
RFLVAGMGDALATWFEARSCHATRSANACGGLSTLTGLNLARLCYDTLLRYGAAAKTAAEQQIITPALEHIIEANTLLSG
IGFESGGLASAHSIHNGLTALAETHAFYHGEKVAFGLLAGLQLIDAPPEEINEVYRFCEAVGLPTTLAAVGLAGCGRDRL
LQVAQKACAPEECIHHEAGSITPDKVLNAMLAADAIGTRRKSV
>Mature_363_residues
MLNKAMFPGKYLQGAAALNELPALVQLFGRQGLILASATACDRILPDSGIDLKRHNLSLERFNGECCEQELTRLAAVIKA
KQVDVLVGMGGGKAIDTAKIAADRAGIPVIIVPTIASTDAPCSGCAVLYSAQGVFESVYYQRSNPAAVLVDSAIIVRAPV
RFLVAGMGDALATWFEARSCHATRSANACGGLSTLTGLNLARLCYDTLLRYGAAAKTAAEQQIITPALEHIIEANTLLSG
IGFESGGLASAHSIHNGLTALAETHAFYHGEKVAFGLLAGLQLIDAPPEEINEVYRFCEAVGLPTTLAAVGLAGCGRDRL
LQVAQKACAPEECIHHEAGSITPDKVLNAMLAADAIGTRRKSV

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions [H]

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=359, Percent_Identity=46.2395543175487, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1786815, Length=357, Percent_Identity=31.0924369747899, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 38019; Mature: 38019

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKAMFPGKYLQGAAALNELPALVQLFGRQGLILASATACDRILPDSGIDLKRHNLSLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCCCCHHHCCCHH
RFNGECCEQELTRLAAVIKAKQVDVLVGMGGGKAIDTAKIAADRAGIPVIIVPTIASTDA
HCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCC
PCSGCAVLYSAQGVFESVYYQRSNPAAVLVDSAIIVRAPVRFLVAGMGDALATWFEARSC
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HATRSANACGGLSTLTGLNLARLCYDTLLRYGAAAKTAAEQQIITPALEHIIEANTLLSG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFESGGLASAHSIHNGLTALAETHAFYHGEKVAFGLLAGLQLIDAPPEEINEVYRFCEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VGLPTTLAAVGLAGCGRDRLLQVAQKACAPEECIHHEAGSITPDKVLNAMLAADAIGTRR
HCCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
KSV
CCC
>Mature Secondary Structure
MLNKAMFPGKYLQGAAALNELPALVQLFGRQGLILASATACDRILPDSGIDLKRHNLSLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCCCCHHHCCCHH
RFNGECCEQELTRLAAVIKAKQVDVLVGMGGGKAIDTAKIAADRAGIPVIIVPTIASTDA
HCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCC
PCSGCAVLYSAQGVFESVYYQRSNPAAVLVDSAIIVRAPVRFLVAGMGDALATWFEARSC
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HATRSANACGGLSTLTGLNLARLCYDTLLRYGAAAKTAAEQQIITPALEHIIEANTLLSG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFESGGLASAHSIHNGLTALAETHAFYHGEKVAFGLLAGLQLIDAPPEEINEVYRFCEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VGLPTTLAAVGLAGCGRDRLLQVAQKACAPEECIHHEAGSITPDKVLNAMLAADAIGTRR
HCCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
KSV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12193646 [H]