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The map label for this gene is uppP

Identifier: 189423595

GI number: 189423595

Start: 495683

End: 496501

Strand: Reverse

Name: uppP

Synonym: Glov_0524

Alternate gene names: 189423595

Gene position: 496501-495683 (Counterclockwise)

Preceding gene: 189423596

Following gene: 189423594

Centisome position: 12.67

GC content: 58.36

Gene sequence:

>819_bases
ATGGACCTGCTGCATGCCGCCCTGCTGGGCCTGATTCAGGGTGCCACTGAAGTACTGCCGATCAGCAGCTCCGGCCACCT
GATCCTGATCCCCCGCCTGCTGGGCTGGCCCGATTCCGGGTTGACCTTTGATGTTGCCCTGCACTTTGGTACCTTTCTGG
CCATTTTTGTCTACTTCCGCAAAGACGTTGTTAGCCTGGTACAGGATGGCCTGACCGGTTTTTTCCAGCCGGAAGCCCCC
CGTAGGCTGCGGCTGCCCTGGATGATCGTACTGGCCTCGATACCTGCGGCCATTGCAGGTAAAACCCTTGAACAGCCGAT
TGAAGAACTCTTCCGCAGCAGCCCGCTGATGATCGCCCTGATGCTGATTCTGTTCGGACTGGGGTTAGGACTGACTGACC
GTTACGGCAAAAAACTGCACGACGTTGCCTCAATCACCCTGGGCACAGCCATGCTGGTGGGTTGTTTTCAATGCCTGGCC
CTGGTGCCGGGGGTTTCCCGTTCCGGTATCACCATCACTGCCGGACTGCTGCTGGGGCTGGCCCGCACTGATGCGGCCCG
TTTTTCATTCCTGCTCTCGCTGCCGATTGTGTTTGGCGCTGCCCTGCTGAAAGGGCTCCACCTGTTGAAACATGGTATTG
AACCGGGTATGGCGATGCCGATGCTGGTGGGGGTAGCAGTTTCGGCGGTTGTCGGCTATATCAGCGTTGCCTTTTTGCTG
AAGTTTGTACAGAGCCGCACGCTCTGGCCGTTTGTCTGGTATCGGGTGGCAGCAGGTATCGGGGTTATGGCACTTCTGGG
GGTTGGCCTGCTGTCATGA

Upstream 100 bases:

>100_bases
TCCACTGTCGTTTCAGAGGCGTTCCATCAGGGCAGGCAGGATGGCGCGTCTCTACGCTTGCACCCCACCATGAAACACCT
TCCTAAGGAGTAAGAGACCA

Downstream 100 bases:

>100_bases
GCAACAATGCCATCAAAGACTGGCCGGAAGATGAACGGCCACGGGAAAAGCTGCTCAAACGTGGCGCTGCAGCCCTGTCC
GATGCAGAGCTGCTGGCCCT

Product: undecaprenol kinase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MDLLHAALLGLIQGATEVLPISSSGHLILIPRLLGWPDSGLTFDVALHFGTFLAIFVYFRKDVVSLVQDGLTGFFQPEAP
RRLRLPWMIVLASIPAAIAGKTLEQPIEELFRSSPLMIALMLILFGLGLGLTDRYGKKLHDVASITLGTAMLVGCFQCLA
LVPGVSRSGITITAGLLLGLARTDAARFSFLLSLPIVFGAALLKGLHLLKHGIEPGMAMPMLVGVAVSAVVGYISVAFLL
KFVQSRTLWPFVWYRVAAGIGVMALLGVGLLS

Sequences:

>Translated_272_residues
MDLLHAALLGLIQGATEVLPISSSGHLILIPRLLGWPDSGLTFDVALHFGTFLAIFVYFRKDVVSLVQDGLTGFFQPEAP
RRLRLPWMIVLASIPAAIAGKTLEQPIEELFRSSPLMIALMLILFGLGLGLTDRYGKKLHDVASITLGTAMLVGCFQCLA
LVPGVSRSGITITAGLLLGLARTDAARFSFLLSLPIVFGAALLKGLHLLKHGIEPGMAMPMLVGVAVSAVVGYISVAFLL
KFVQSRTLWPFVWYRVAAGIGVMALLGVGLLS
>Mature_272_residues
MDLLHAALLGLIQGATEVLPISSSGHLILIPRLLGWPDSGLTFDVALHFGTFLAIFVYFRKDVVSLVQDGLTGFFQPEAP
RRLRLPWMIVLASIPAAIAGKTLEQPIEELFRSSPLMIALMLILFGLGLGLTDRYGKKLHDVASITLGTAMLVGCFQCLA
LVPGVSRSGITITAGLLLGLARTDAARFSFLLSLPIVFGAALLKGLHLLKHGIEPGMAMPMLVGVAVSAVVGYISVAFLL
KFVQSRTLWPFVWYRVAAGIGVMALLGVGLLS

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=273, Percent_Identity=36.6300366300366, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_GEOLS (B3E340)

Other databases:

- EMBL:   CP001089
- RefSeq:   YP_001950772.1
- GeneID:   6367544
- GenomeReviews:   CP001089_GR
- KEGG:   glo:Glov_0524
- HOGENOM:   HBG391969
- OMA:   FALLWYF
- ProtClustDB:   CLSK827794
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29044; Mature: 29044

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1274edac)-; HASH(0x13256b3c)-; HASH(0x13259e0c)-; HASH(0x13262014)-; HASH(0x13259dc4)-; HASH(0x13259ef0)-; HASH(0x12966e04)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLHAALLGLIQGATEVLPISSSGHLILIPRLLGWPDSGLTFDVALHFGTFLAIFVYFR
CHHHHHHHHHHHHCCHHEEEECCCCCEEEEHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KDVVSLVQDGLTGFFQPEAPRRLRLPWMIVLASIPAAIAGKTLEQPIEELFRSSPLMIAL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLILFGLGLGLTDRYGKKLHDVASITLGTAMLVGCFQCLALVPGVSRSGITITAGLLLGL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ARTDAARFSFLLSLPIVFGAALLKGLHLLKHGIEPGMAMPMLVGVAVSAVVGYISVAFLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KFVQSRTLWPFVWYRVAAGIGVMALLGVGLLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDLLHAALLGLIQGATEVLPISSSGHLILIPRLLGWPDSGLTFDVALHFGTFLAIFVYFR
CHHHHHHHHHHHHCCHHEEEECCCCCEEEEHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KDVVSLVQDGLTGFFQPEAPRRLRLPWMIVLASIPAAIAGKTLEQPIEELFRSSPLMIAL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLILFGLGLGLTDRYGKKLHDVASITLGTAMLVGCFQCLALVPGVSRSGITITAGLLLGL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ARTDAARFSFLLSLPIVFGAALLKGLHLLKHGIEPGMAMPMLVGVAVSAVVGYISVAFLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KFVQSRTLWPFVWYRVAAGIGVMALLGVGLLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA