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The map label for this gene is fkpB [C]

Identifier: 189423483

GI number: 189423483

Start: 394784

End: 395281

Strand: Reverse

Name: fkpB [C]

Synonym: Glov_0412

Alternate gene names: 189423483

Gene position: 395281-394784 (Counterclockwise)

Preceding gene: 189423484

Following gene: 189423474

Centisome position: 10.09

GC content: 58.43

Gene sequence:

>498_bases
ATGGCACAGGCACAACAGGGCGATACCGTCCGGGTACACTACACCGGCACCCTGCAGGACGGCTCAATTTTCGACTCTTC
CGAGACAGTAGAACAGGACAGCTGCGGCTGTAGCTGCAGCAGTTCCGGCGGCTGCGGCACCGGCAGCGACTGCGGCTGCG
AGCCGCTTGAATTCACCATCGGCGGCGGCAACGTCATACCCGGTTTTGAAAAAGCGGTGCTGGGACTTTCCGTAGGCGAG
AGCATCAAGGTGACCATTCCGGCTGACGAGGCCTATGGCCCCCGGCATGAGCAGATGGTTGCAGTGGTCGACCGGTCAGA
GCTGAGCGGCGAAATAGAACCGATTGAAGGACAGCAACTTGAGGTGGTTTTGCAGGATGATTCATCCATGCCGGTCCTGA
TCACCGAAGTAACCGAGACCACCGTCACCCTGGATGCCAACCATCCGCTGGCCGGACAGGATCTGACCTTTGAGATCAAA
CTGGTAGAGATCGTTTAG

Upstream 100 bases:

>100_bases
GAGCCACCACGCAACAGATTGAACAGCTGATCCCCCCCGCATAACTTCAGTTCCTGCTCCCTGGAAGGGCAGGTTATTTA
TGGCATGAAAGGACATTCCA

Downstream 100 bases:

>100_bases
CCTTCTTGACGGAAACGCCGTAAAAGACCTCGTTTCCGGAATCAATCAGTGCAGCAGGTGCAGTACAAACAAAAGGGCTG
CCCGGATTACCGGGCAGCCC

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MAQAQQGDTVRVHYTGTLQDGSIFDSSETVEQDSCGCSCSSSGGCGTGSDCGCEPLEFTIGGGNVIPGFEKAVLGLSVGE
SIKVTIPADEAYGPRHEQMVAVVDRSELSGEIEPIEGQQLEVVLQDDSSMPVLITEVTETTVTLDANHPLAGQDLTFEIK
LVEIV

Sequences:

>Translated_165_residues
MAQAQQGDTVRVHYTGTLQDGSIFDSSETVEQDSCGCSCSSSGGCGTGSDCGCEPLEFTIGGGNVIPGFEKAVLGLSVGE
SIKVTIPADEAYGPRHEQMVAVVDRSELSGEIEPIEGQQLEVVLQDDSSMPVLITEVTETTVTLDANHPLAGQDLTFEIK
LVEIV
>Mature_164_residues
AQAQQGDTVRVHYTGTLQDGSIFDSSETVEQDSCGCSCSSSGGCGTGSDCGCEPLEFTIGGGNVIPGFEKAVLGLSVGES
IKVTIPADEAYGPRHEQMVAVVDRSELSGEIEPIEGQQLEVVLQDDSSMPVLITEVTETTVTLDANHPLAGQDLTFEIKL
VEIV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=160, Percent_Identity=28.75, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789748, Length=110, Percent_Identity=36.3636363636364, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17308; Mature: 17177

Theoretical pI: Translated: 3.72; Mature: 3.72

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAQQGDTVRVHYTGTLQDGSIFDSSETVEQDSCGCSCSSSGGCGTGSDCGCEPLEFTI
CCCCCCCCEEEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
GGGNVIPGFEKAVLGLSVGESIKVTIPADEAYGPRHEQMVAVVDRSELSGEIEPIEGQQL
CCCCCCCCHHHEEEEEECCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEE
EVVLQDDSSMPVLITEVTETTVTLDANHPLAGQDLTFEIKLVEIV
EEEEECCCCCCEEEEEECEEEEEEECCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
AQAQQGDTVRVHYTGTLQDGSIFDSSETVEQDSCGCSCSSSGGCGTGSDCGCEPLEFTI
CCCCCCCEEEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
GGGNVIPGFEKAVLGLSVGESIKVTIPADEAYGPRHEQMVAVVDRSELSGEIEPIEGQQL
CCCCCCCCHHHEEEEEECCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEE
EVVLQDDSSMPVLITEVTETTVTLDANHPLAGQDLTFEIKLVEIV
EEEEECCCCCCEEEEEECEEEEEEECCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]