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The map label for this gene is degA [H]

Identifier: 189354073

GI number: 189354073

Start: 2409001

End: 2410017

Strand: Reverse

Name: degA [H]

Synonym: BMULJ_05326

Alternate gene names: 189354073

Gene position: 2410017-2409001 (Counterclockwise)

Preceding gene: 189354081

Following gene: 189354070

Centisome position: 97.45

GC content: 72.76

Gene sequence:

>1017_bases
ATGGCGACTCTCGATGAAGTGGCGCGCCGTGCGGGCGTGACGGCCGCGACGGTGTCGAACGTGCTGCGCGGCCGCGGGCG
CGTCGGCGATGCGACGCGCGCGCGCGTGCTGGAAGCCGTGCAGACGCTCGGCTACCGCCCGCATCTCGCCGCGCGGGCGC
TCGCGGAGGGACGCGCGCCGACGGTCGCGCTGATGGTGTCGAGCATCGCGAACCCGTTCTATCCCGAGTTCGCGCTCGCG
GTCGAGCGCGCGGTGCGGCGCAACGGGCAGTTTCTGATCGTCTGCAATACCAACGACGATCCGGCGCAGGGGCGCGCCTA
TCTGGACCAGATTGCCGGCACGGTGTCCGAAGGCATCCTCGTGACGAACGCGAGCCATCTGCCGGACCTGCTCGAGGTGA
CGCGGCGCGGCGTGCCGGTCGTGCTCTGCATGTGGGAGCGGCCGGACGCGCCGCCCGACGGGCTGCCGTGCGTCGCGGTC
GATTTCCGCGAGGCGGGGCGGATCGCGACGCGCCATCTGCTCGAGCTCGGTCACGAGCGGATCGGCGCGATCGTCGGCGG
GTGCGCGGGCGGCGTGCAGGCCGCGCGTTACGACGGTTTCGCCGACGTGATGCGCGAAGCGGGGCTCGACGCGTCGATCG
TCGAGGCCGAGCCCGATTCGATCGAAGGCGGGCTGCGCGCGGCAGCGCGATTGCTCGATGCGCATCCCGAACTCACGGCG
CTGCTTGCGACCAACGATCTGCCGGCGATCGGCGCGCTGCATGCGGCCGCCGATCGCGGGCTGCGCGTGCCGGACGATCT
GTCGATCGTCGGCATCACCGACATTCAGCTCGCGCGCGATACGCGTCCGACGCTGACGACGGTCGCGATCCCGACCGCCG
AGGCCGCGGCGCTCGCGGTGGATCTGCTCAATGCGTTGCGCGAGGCCGGCGGTCGGGTCGACGATGCGGCGCGCGTCAGG
ACGGCGTCGGCGCCGCGGCTCGTGGTGCGCGGCACGACAGGCGTGGCGCGACGGTGA

Upstream 100 bases:

>100_bases
CTTGGGCGCCCGGCGGTCGGACAGCAGGGCGTGCGACGATAGTGCGCCGCTTCGCACGGCGAAGCAAATACTGGATGGGC
TTCTCAGATAGTGAGCAAAC

Downstream 100 bases:

>100_bases
CGTACCGGCACGGCGCGTACCACGCACGGCGGCGGTCGCCGTGCGCGGCGCGCAGCGGGACTAGAACGTGTAAGAGAGCG
ACGCGAACAGGCTGCGCGGC

Product: LacI family putative ribose operon repressor

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MATLDEVARRAGVTAATVSNVLRGRGRVGDATRARVLEAVQTLGYRPHLAARALAEGRAPTVALMVSSIANPFYPEFALA
VERAVRRNGQFLIVCNTNDDPAQGRAYLDQIAGTVSEGILVTNASHLPDLLEVTRRGVPVVLCMWERPDAPPDGLPCVAV
DFREAGRIATRHLLELGHERIGAIVGGCAGGVQAARYDGFADVMREAGLDASIVEAEPDSIEGGLRAAARLLDAHPELTA
LLATNDLPAIGALHAAADRGLRVPDDLSIVGITDIQLARDTRPTLTTVAIPTAEAAALAVDLLNALREAGGRVDDAARVR
TASAPRLVVRGTTGVARR

Sequences:

>Translated_338_residues
MATLDEVARRAGVTAATVSNVLRGRGRVGDATRARVLEAVQTLGYRPHLAARALAEGRAPTVALMVSSIANPFYPEFALA
VERAVRRNGQFLIVCNTNDDPAQGRAYLDQIAGTVSEGILVTNASHLPDLLEVTRRGVPVVLCMWERPDAPPDGLPCVAV
DFREAGRIATRHLLELGHERIGAIVGGCAGGVQAARYDGFADVMREAGLDASIVEAEPDSIEGGLRAAARLLDAHPELTA
LLATNDLPAIGALHAAADRGLRVPDDLSIVGITDIQLARDTRPTLTTVAIPTAEAAALAVDLLNALREAGGRVDDAARVR
TASAPRLVVRGTTGVARR
>Mature_337_residues
ATLDEVARRAGVTAATVSNVLRGRGRVGDATRARVLEAVQTLGYRPHLAARALAEGRAPTVALMVSSIANPFYPEFALAV
ERAVRRNGQFLIVCNTNDDPAQGRAYLDQIAGTVSEGILVTNASHLPDLLEVTRRGVPVVLCMWERPDAPPDGLPCVAVD
FREAGRIATRHLLELGHERIGAIVGGCAGGVQAARYDGFADVMREAGLDASIVEAEPDSIEGGLRAAARLLDAHPELTAL
LATNDLPAIGALHAAADRGLRVPDDLSIVGITDIQLARDTRPTLTTVAIPTAEAAALAVDLLNALREAGGRVDDAARVRT
ASAPRLVVRGTTGVARR

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789202, Length=301, Percent_Identity=33.5548172757475, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787948, Length=310, Percent_Identity=33.5483870967742, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1790194, Length=316, Percent_Identity=33.5443037974684, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788474, Length=335, Percent_Identity=32.8358208955224, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790369, Length=335, Percent_Identity=31.6417910447761, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=28.476821192053, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI48994940, Length=308, Percent_Identity=26.6233766233766, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790715, Length=308, Percent_Identity=25.3246753246753, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787906, Length=255, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787580, Length=313, Percent_Identity=25.8785942492013, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786540, Length=288, Percent_Identity=25.6944444444444, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789456, Length=322, Percent_Identity=27.9503105590062, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786268, Length=279, Percent_Identity=24.3727598566308, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35489; Mature: 35358

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLDEVARRAGVTAATVSNVLRGRGRVGDATRARVLEAVQTLGYRPHLAARALAEGRAP
CCCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
TVALMVSSIANPFYPEFALAVERAVRRNGQFLIVCNTNDDPAQGRAYLDQIAGTVSEGIL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEE
VTNASHLPDLLEVTRRGVPVVLCMWERPDAPPDGLPCVAVDFREAGRIATRHLLELGHER
EECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
IGAIVGGCAGGVQAARYDGFADVMREAGLDASIVEAEPDSIEGGLRAAARLLDAHPELTA
HHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEE
LLATNDLPAIGALHAAADRGLRVPDDLSIVGITDIQLARDTRPTLTTVAIPTAEAAALAV
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHH
DLLNALREAGGRVDDAARVRTASAPRLVVRGTTGVARR
HHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
ATLDEVARRAGVTAATVSNVLRGRGRVGDATRARVLEAVQTLGYRPHLAARALAEGRAP
CCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
TVALMVSSIANPFYPEFALAVERAVRRNGQFLIVCNTNDDPAQGRAYLDQIAGTVSEGIL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEE
VTNASHLPDLLEVTRRGVPVVLCMWERPDAPPDGLPCVAVDFREAGRIATRHLLELGHER
EECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
IGAIVGGCAGGVQAARYDGFADVMREAGLDASIVEAEPDSIEGGLRAAARLLDAHPELTA
HHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEE
LLATNDLPAIGALHAAADRGLRVPDDLSIVGITDIQLARDTRPTLTTVAIPTAEAAALAV
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHH
DLLNALREAGGRVDDAARVRTASAPRLVVRGTTGVARR
HHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]