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The map label for this gene is aroF [H]

Identifier: 189354039

GI number: 189354039

Start: 2367341

End: 2368471

Strand: Reverse

Name: aroF [H]

Synonym: BMULJ_05292

Alternate gene names: 189354039

Gene position: 2368471-2367341 (Counterclockwise)

Preceding gene: 189354040

Following gene: 189354038

Centisome position: 95.77

GC content: 67.64

Gene sequence:

>1131_bases
ATGCAGAAGCTCGACAATCCCACGCACGATCGCGAGGTCGGCGTCGCCGACGCGACGCTCGATACGACGCGCATCGACGA
CGTCCGTATCGGCGCCGTGCGTCCGCTGATTTCGCCGGCGCTGCTGCTCGACGAACTGCCGGTGCCGGCGGCCACGCAGA
CGCTCGTCGAAGATACGCGCAAGGCGATCGGCGACATCCTGCACGGTCGCGACGACCGGTTGCTGCTCGTCGTCGGCCCA
TGCTCGATCCACGATCACGACCAGGCGCTCGACTACGCGCGCCGCCTCAAGGCCGCCGCCGATGCGCTGAAGGACGATCT
GCTGATCACGATGCGCGTGTACTTCGAGAAGCCGCGCACGACGGTCGGCTGGAAGGGCTACATCAACGATCCGCGTCTCG
ACGGCAGCTTCCGCATCAACGAAGGGCTGCGCGCCGCGCGGCAGCTGCTGCTCGACATCAACGCGCTCGGCCTGCCCGCC
TCGACCGAATTCCTCGATCTGCTGAGCCCGCAGTACATCGCGGACCTGATCGCGTGGGGTGCGATCGGCGCACGCACGAC
CGAGAGCCAGAGCCATCGTCAGCTCGCGTCGGGGCTCAGCTGCCCGATCGGCTTCAAGAACGGCACCGACGGCGGCGTGC
AGGTCGCGTCGGACGCGATCGTCGCCGCGCGCGCGAGCCATGCGTTCATGGGGATGACGAAGATGGGCATGGCCGCGATC
TTCGAGACGCGCGGCAACGACGACGCTCATGTGATTTTGCGCGGCGGCAAGAACGGCCCGAACTACGACGCGGCGCACGT
CGACGCGAGCTGCGCCGTGCTGCGCGCGGCGGGCCTGCGCGAGCAGGTGATGGTCGACTGCTCGCATGCGAATTCGAACA
AGTCGCACGAGCGGCAGATCGAGGTCGCGCAGGATCTCGCGCGCCAGCTGTCGCAGGGCGAGCACCGCATCGTCGGCGTG
ATGATCGAGAGCCATCTCGAAGCCGGCCGTCAGGATCTGAAGCCCGGCGTGCCGTTGAAGTACGGCGTATCGATCACCGA
TGCATGCCTGAGCTGGGCGCAGACCGAACCGGTGCTCGACGTGCTCGCCGAAGCCGTGCGTCATCGCCGCGTGTTCGCGC
GCAACGCGTGA

Upstream 100 bases:

>100_bases
TCGGGATCGACGCCGACGCGCCGGGCGACGCGAACTGACGCCCGATGCGGGTGCCATAATCGAGCCTGCCGATCCATCCA
GACGCCCGCGGAGAATTCCC

Downstream 100 bases:

>100_bases
CGGTGCGCGCGCACTGCGACATCGTGCTCGCTGCAGCGCTTTCGCGCAAACGTTAACATGGGCCGTGCGACGTATCGACG
GCCCGCGATGCCGGCCCCGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MQKLDNPTHDREVGVADATLDTTRIDDVRIGAVRPLISPALLLDELPVPAATQTLVEDTRKAIGDILHGRDDRLLLVVGP
CSIHDHDQALDYARRLKAAADALKDDLLITMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRAARQLLLDINALGLPA
STEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIVAARASHAFMGMTKMGMAAI
FETRGNDDAHVILRGGKNGPNYDAAHVDASCAVLRAAGLREQVMVDCSHANSNKSHERQIEVAQDLARQLSQGEHRIVGV
MIESHLEAGRQDLKPGVPLKYGVSITDACLSWAQTEPVLDVLAEAVRHRRVFARNA

Sequences:

>Translated_376_residues
MQKLDNPTHDREVGVADATLDTTRIDDVRIGAVRPLISPALLLDELPVPAATQTLVEDTRKAIGDILHGRDDRLLLVVGP
CSIHDHDQALDYARRLKAAADALKDDLLITMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRAARQLLLDINALGLPA
STEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIVAARASHAFMGMTKMGMAAI
FETRGNDDAHVILRGGKNGPNYDAAHVDASCAVLRAAGLREQVMVDCSHANSNKSHERQIEVAQDLARQLSQGEHRIVGV
MIESHLEAGRQDLKPGVPLKYGVSITDACLSWAQTEPVLDVLAEAVRHRRVFARNA
>Mature_376_residues
MQKLDNPTHDREVGVADATLDTTRIDDVRIGAVRPLISPALLLDELPVPAATQTLVEDTRKAIGDILHGRDDRLLLVVGP
CSIHDHDQALDYARRLKAAADALKDDLLITMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRAARQLLLDINALGLPA
STEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIVAARASHAFMGMTKMGMAAI
FETRGNDDAHVILRGGKNGPNYDAAHVDASCAVLRAAGLREQVMVDCSHANSNKSHERQIEVAQDLARQLSQGEHRIVGV
MIESHLEAGRQDLKPGVPLKYGVSITDACLSWAQTEPVLDVLAEAVRHRRVFARNA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=59.1304347826087, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=51.7341040462428, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1788953, Length=336, Percent_Identity=52.3809523809524, Blast_Score=361, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320240, Length=357, Percent_Identity=52.3809523809524, Blast_Score=373, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6319726, Length=352, Percent_Identity=55.3977272727273, Blast_Score=371, Evalue=1e-103,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 40818; Mature: 40818

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLDNPTHDREVGVADATLDTTRIDDVRIGAVRPLISPALLLDELPVPAATQTLVEDTR
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KAIGDILHGRDDRLLLVVGPCSIHDHDQALDYARRLKAAADALKDDLLITMRVYFEKPRT
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
TVGWKGYINDPRLDGSFRINEGLRAARQLLLDINALGLPASTEFLDLLSPQYIADLIAWG
CCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHH
AIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIVAARASHAFMGMTKMGMAAI
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FETRGNDDAHVILRGGKNGPNYDAAHVDASCAVLRAAGLREQVMVDCSHANSNKSHERQI
HHCCCCCCEEEEEECCCCCCCCCCHHCCHHHHHHHHCCCCHHHEEEECCCCCCCHHHHHH
EVAQDLARQLSQGEHRIVGVMIESHLEAGRQDLKPGVPLKYGVSITDACLSWAQTEPVLD
HHHHHHHHHHHCCCCEEEHHHHHHHHHHCHHHCCCCCCEEECCCHHHHHHHHHCCCHHHH
VLAEAVRHRRVFARNA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKLDNPTHDREVGVADATLDTTRIDDVRIGAVRPLISPALLLDELPVPAATQTLVEDTR
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KAIGDILHGRDDRLLLVVGPCSIHDHDQALDYARRLKAAADALKDDLLITMRVYFEKPRT
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCC
TVGWKGYINDPRLDGSFRINEGLRAARQLLLDINALGLPASTEFLDLLSPQYIADLIAWG
CCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHH
AIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIVAARASHAFMGMTKMGMAAI
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FETRGNDDAHVILRGGKNGPNYDAAHVDASCAVLRAAGLREQVMVDCSHANSNKSHERQI
HHCCCCCCEEEEEECCCCCCCCCCHHCCHHHHHHHHCCCCHHHEEEECCCCCCCHHHHHH
EVAQDLARQLSQGEHRIVGVMIESHLEAGRQDLKPGVPLKYGVSITDACLSWAQTEPVLD
HHHHHHHHHHHCCCCEEEHHHHHHHHHHCHHHCCCCCCEEECCCHHHHHHHHHCCCHHHH
VLAEAVRHRRVFARNA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]