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The map label for this gene is dtpB [H]

Identifier: 189354011

GI number: 189354011

Start: 2339766

End: 2341286

Strand: Direct

Name: dtpB [H]

Synonym: BMULJ_05264

Alternate gene names: 189354011

Gene position: 2339766-2341286 (Clockwise)

Preceding gene: 189354003

Following gene: 189354012

Centisome position: 94.61

GC content: 65.75

Gene sequence:

>1521_bases
ATGATGCACGCACCTGTTTCACAAACCCGATCGTTTACGACGGTCTTCCTCATCGAAATGTGGGAGCGCTTCGGCTACTA
CGGCATGGCCGCGCTCCTGGTCCTCTTCATGGTCGACAGGCTCGGTTTCACCGACAGCCATGCGAACCTCACGTGGGGTG
CGTTCACCGCACTCGTCTACGCCTCGCCGTCGATCGGCGGCTGGATCGGCGACAAGGTGCTCGGCGCGCGCCGCACGATG
ATCCTCGGCGCGGCCGTGCTGTGCGCCGGCTACCTGATGCTGTCGATTCCGAACGACGCGCTCGCCTATATGTATGCGTC
GCTCGGCGTGATCGTCGTCGGCAACGGGCTGTTCAAGGCCAACGCGGCGAACCTCGTGCGCCGCATCTACGAAGGCGACG
ACGCGCGCATCGACAGCGCGTTCACGATCTACTACATGGCGGTCAACATCGGCTCGACGGTGTCGATGCTCGCGACGCCG
TGGATCAAGGATCACTGGGGCTGGCACACCGCGTTCGCGGTCTGCTGCGGCGGCATGCTGCTCGCGATCCTGAACTTCAT
GCTGATGCATCGCACGCTCGCGCACATCGGCTCGCAGCCCGACGACGAGCCGATCCGCTGGAAGCGCCTCGGCGCGGTCG
CGGCAGGCGGCGTCGCGCTTGCGCTCGTCACGCTGTACGTGCTGCAGCACAAGCAACTGGCAGTGGCAAGCGTGTGGACG
GCCGCGGTCGCGATCCTCGCGATCTTCGCGTACATGATCGCGAAGTCGGAACGCTCGGAGCGCGCCGGCCTGATCGCCGC
GCTCGTGCTGATCGCGCAGGTGATCCTGTTCTTCATCTTCTACGTGCAGATGTCGACGTCGCTGACGCTGTTCGCGCTGC
GCAACGTCGATCCACGCTTCATCCTGTTCGGCACGACGCTGTTTACGTGGAGCGCCGCCCAGTTCCAGGCGCTGAACCCG
ATCTGGATCATGCTGCTGAGCCCGGTGCTCGTGTGGATCTACAACGCGTTCTCGAAGGGCGGCCGCGATCTGCCGGTCGC
CGCGAAGTACGCGCTCGGCTTTGGCGCCGTCGCCGCCGGCTATCTCGTGTTCACGATCAGCGGCCGCTATGCGGTCGACG
GCCGCGTGTCGTCGTGGTTCATGGTGGGGGGCTACGGCCTCTACTCGCTCGGCGAACTGCTCGTGAGCGGCCTCGGCCTC
GCGATGATCGCGCGCTACGTGCCGGCGCGGATGAGCGGCTTCATGATGGGCGCGTACTTCGTCGCGACCGGCGTGTCGCA
GTATCTCGGCAGCGTCGTCGCGAACTTCGCGCAGATGCCGTCGCACGATCTGCCGGCCGTCGATTCGCTGCCGCTCTATC
TGTCGCTGTTCGAGAAGCTCGGCTGGCTCGCCGCGATCGGCATGGTGCTCGCGCTGCTGCTGCTGCCGATGATGAACCGC
CTGTCGCGCCAGCATCAGCGCTGCGCGGAAGAGCGCCGCGACGAAGCGCTGCAGGCGCAGAACGTCGCCGCCGTTCAGTA
A

Upstream 100 bases:

>100_bases
TGCCATTGCCTGCGTAGCGGCCTACCCGGCCCACGCGCCCAGGCGCCAGTTCTACCCTCAGGCGACGCGCGATCCGCGCC
GTCCGTTTCAACCGAGATTG

Downstream 100 bases:

>100_bases
GTCCGGCGGCCGGCGTGCTGCGCGCACGCCACAGGGCGCCACATTCTCCTGCCGGCACCGCAATCGCGTCCTACACTGAT
TGCAAGCGGCGCATCCCCCG

Product: POT family proton-dependent oligopeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MMHAPVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDRLGFTDSHANLTWGAFTALVYASPSIGGWIGDKVLGARRTM
ILGAAVLCAGYLMLSIPNDALAYMYASLGVIVVGNGLFKANAANLVRRIYEGDDARIDSAFTIYYMAVNIGSTVSMLATP
WIKDHWGWHTAFAVCCGGMLLAILNFMLMHRTLAHIGSQPDDEPIRWKRLGAVAAGGVALALVTLYVLQHKQLAVASVWT
AAVAILAIFAYMIAKSERSERAGLIAALVLIAQVILFFIFYVQMSTSLTLFALRNVDPRFILFGTTLFTWSAAQFQALNP
IWIMLLSPVLVWIYNAFSKGGRDLPVAAKYALGFGAVAAGYLVFTISGRYAVDGRVSSWFMVGGYGLYSLGELLVSGLGL
AMIARYVPARMSGFMMGAYFVATGVSQYLGSVVANFAQMPSHDLPAVDSLPLYLSLFEKLGWLAAIGMVLALLLLPMMNR
LSRQHQRCAEERRDEALQAQNVAAVQ

Sequences:

>Translated_506_residues
MMHAPVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDRLGFTDSHANLTWGAFTALVYASPSIGGWIGDKVLGARRTM
ILGAAVLCAGYLMLSIPNDALAYMYASLGVIVVGNGLFKANAANLVRRIYEGDDARIDSAFTIYYMAVNIGSTVSMLATP
WIKDHWGWHTAFAVCCGGMLLAILNFMLMHRTLAHIGSQPDDEPIRWKRLGAVAAGGVALALVTLYVLQHKQLAVASVWT
AAVAILAIFAYMIAKSERSERAGLIAALVLIAQVILFFIFYVQMSTSLTLFALRNVDPRFILFGTTLFTWSAAQFQALNP
IWIMLLSPVLVWIYNAFSKGGRDLPVAAKYALGFGAVAAGYLVFTISGRYAVDGRVSSWFMVGGYGLYSLGELLVSGLGL
AMIARYVPARMSGFMMGAYFVATGVSQYLGSVVANFAQMPSHDLPAVDSLPLYLSLFEKLGWLAAIGMVLALLLLPMMNR
LSRQHQRCAEERRDEALQAQNVAAVQ
>Mature_506_residues
MMHAPVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDRLGFTDSHANLTWGAFTALVYASPSIGGWIGDKVLGARRTM
ILGAAVLCAGYLMLSIPNDALAYMYASLGVIVVGNGLFKANAANLVRRIYEGDDARIDSAFTIYYMAVNIGSTVSMLATP
WIKDHWGWHTAFAVCCGGMLLAILNFMLMHRTLAHIGSQPDDEPIRWKRLGAVAAGGVALALVTLYVLQHKQLAVASVWT
AAVAILAIFAYMIAKSERSERAGLIAALVLIAQVILFFIFYVQMSTSLTLFALRNVDPRFILFGTTLFTWSAAQFQALNP
IWIMLLSPVLVWIYNAFSKGGRDLPVAAKYALGFGAVAAGYLVFTISGRYAVDGRVSSWFMVGGYGLYSLGELLVSGLGL
AMIARYVPARMSGFMMGAYFVATGVSQYLGSVVANFAQMPSHDLPAVDSLPLYLSLFEKLGWLAAIGMVLALLLLPMMNR
LSRQHQRCAEERRDEALQAQNVAAVQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=391, Percent_Identity=23.7851662404092, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI226371746, Length=347, Percent_Identity=24.207492795389, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787922, Length=478, Percent_Identity=39.3305439330544, Blast_Score=356, Evalue=2e-99,
Organism=Escherichia coli, GI1789911, Length=478, Percent_Identity=37.2384937238494, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1786927, Length=495, Percent_Identity=30.3030303030303, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1790572, Length=482, Percent_Identity=32.1576763485477, Blast_Score=203, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71987453, Length=351, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639585, Length=209, Percent_Identity=29.6650717703349, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639583, Length=209, Percent_Identity=29.6650717703349, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639581, Length=209, Percent_Identity=29.6650717703349, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571098, Length=386, Percent_Identity=24.3523316062176, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28571102, Length=386, Percent_Identity=24.3523316062176, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28571100, Length=386, Percent_Identity=24.3523316062176, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55263; Mature: 55263

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHAPVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDRLGFTDSHANLTWGAFTALVY
CCCCCCHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ASPSIGGWIGDKVLGARRTMILGAAVLCAGYLMLSIPNDALAYMYASLGVIVVGNGLFKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCEEEEECCCCCC
NAANLVRRIYEGDDARIDSAFTIYYMAVNIGSTVSMLATPWIKDHWGWHTAFAVCCGGML
CHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHCCCHHHCCCHHHHHHHHHHHHH
LAILNFMLMHRTLAHIGSQPDDEPIRWKRLGAVAAGGVALALVTLYVLQHKQLAVASVWT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVAILAIFAYMIAKSERSERAGLIAALVLIAQVILFFIFYVQMSTSLTLFALRNVDPRF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCE
ILFGTTLFTWSAAQFQALNPIWIMLLSPVLVWIYNAFSKGGRDLPVAAKYALGFGAVAAG
EEEEHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
YLVFTISGRYAVDGRVSSWFMVGGYGLYSLGELLVSGLGLAMIARYVPARMSGFMMGAYF
EEEEEECCCEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATGVSQYLGSVVANFAQMPSHDLPAVDSLPLYLSLFEKLGWLAAIGMVLALLLLPMMNR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRQHQRCAEERRDEALQAQNVAAVQ
HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMHAPVSQTRSFTTVFLIEMWERFGYYGMAALLVLFMVDRLGFTDSHANLTWGAFTALVY
CCCCCCHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ASPSIGGWIGDKVLGARRTMILGAAVLCAGYLMLSIPNDALAYMYASLGVIVVGNGLFKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCEEEEECCCCCC
NAANLVRRIYEGDDARIDSAFTIYYMAVNIGSTVSMLATPWIKDHWGWHTAFAVCCGGML
CHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHCCCHHHCCCHHHHHHHHHHHHH
LAILNFMLMHRTLAHIGSQPDDEPIRWKRLGAVAAGGVALALVTLYVLQHKQLAVASVWT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVAILAIFAYMIAKSERSERAGLIAALVLIAQVILFFIFYVQMSTSLTLFALRNVDPRF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCE
ILFGTTLFTWSAAQFQALNPIWIMLLSPVLVWIYNAFSKGGRDLPVAAKYALGFGAVAAG
EEEEHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
YLVFTISGRYAVDGRVSSWFMVGGYGLYSLGELLVSGLGLAMIARYVPARMSGFMMGAYF
EEEEEECCCEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATGVSQYLGSVVANFAQMPSHDLPAVDSLPLYLSLFEKLGWLAAIGMVLALLLLPMMNR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRQHQRCAEERRDEALQAQNVAAVQ
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA