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The map label for this gene is prpR [H]

Identifier: 189353986

GI number: 189353986

Start: 2309187

End: 2311169

Strand: Direct

Name: prpR [H]

Synonym: BMULJ_05239

Alternate gene names: 189353986

Gene position: 2309187-2311169 (Clockwise)

Preceding gene: 189353980

Following gene: 189353988

Centisome position: 93.37

GC content: 72.21

Gene sequence:

>1983_bases
ATGGACCTCTCTTCGATCAAGCCGGCCGGCGCCGCCGACCGCACGGTGCGCCCGCGCATCTGGGCGATGGGCATCAGCCG
GTTGCGCGACCTGTTTCGCGAAATCGCCGGCGAATTCGACGAACGCGCGGACGTGCGCATCGTCACGCGCGCGTACGAGG
ATGCGCTCGGCGCCATCGCCGAGGCCGGCACCGCGCGGCCCGACGTGATCGTCGCGGCCGGCTCGAACGGCGGCTTCCTG
AAGACGCGCGCGCAGGTGCCCGTCGTCGTCGTGTCGCCGACCGGCTTCGACGTGATGCAGGCGCTCGCGCGCGCACGGCG
CGATGCGACGCGCATCGCGCTCGTCAGCGCCGGCGACACGCCGCCCGAAGTGCGCCGCTTCGTCGCCGCGTACGGTCTGG
ACGTGCAGTTTGCGTCATATCAGACCGCACAGGAAGCCGAAGCGTGCGTGCACGATCTGCGCGATCGCGGCATCGAAACG
ATCGTCGGGCCCGGCCTCGTCACCGATCTCGCGGCAAGCGCCGGGATGGGCGCCGTGTTCCTGTATTCGCACGCATCGGT
GCGCAGGGCCGTCGAAACGGCGCTCGAAGTCGCGTACGCGACGCATGCCGAAGCGTTTCGCCGCCAGCGGCTCGACACGC
TGCTCCAGCATCTGCGCGACGGCGTCGTCGCGCTCGACGCGCAGGGCCGCGTCGAGGCGATCAACGAGCGGCTCGCGTCG
GCGCTCGGCGTCGAGCCGTCGGCCGCGGTCGGCCGCGCGCTCGTCGATCTGCGGCCCGAGCTGCGCACGCTGCGCGGCGA
GGACGGCGATGCGCTCGCGACCGTGCGCGGCGTGCGCTACGTCGTGCATCGCGGGCCGCTCGTCGATCGCGGCGTCACGT
CCGGCAGCGTGCTGACGTTCCAGGAATCGCGCGCGGTCGAGCGGCTCGATCGCGCGCTGCGCTCGCAGCCGAACACGCAG
CAGTTCGCCGCGCGCTATTCGCTCGACGACGTCGTCGGCGCATCCGCGCCGATGACGCGCGTGCGAGAGCTCGTGCGCCG
CTACGCGAAATCCGACGCGACCGTGCTCGTGCTCGGCGAAAGCGGCACCGGCAAGGAGATGATCGCGCAGAGCCTGCATG
CGCTCTCCGCGCGACGCAGCTATCCGTTCGTCGCGGTCAATTGCGGCGCATTTCCGGAAGCGCTGCTCGAAAGCGAGCTG
TTCGGCTACGAGGAAGGCGCGTTTACGGGCGCGCGCCGCGGCGGCAAGACCGGGCTGTTCGAGGCCGCGCATCGCGGCAC
GCTGTTTCTCGACGAGATCGGCGAAATGCCGCCGTCGCTGCAAAGCCGGCTGCTGCGCGTACTGCAGGAGCGCGAGGTGA
TCCGCCTCGGCTCGACCGAACCGATCCGCATCGACGTGCGCGTGATCGCCGCGACGCACCGGCCGCTGCTCGCGGCCGTC
GAGGCCGGCACGTTCCGCGCCGATCTCTATTACCGGCTCAACATCCTGAATGTCGGCCTGCCGCCGCTGCGCGAACGCGC
GGCCGACATTCCCGCGCTCGCCGCGACGCTGCTCGTGCAGGCCGCGCGGCGCGAGCCGCGGCTCGCGGAGCGGCTGCGCG
ACGCCGACGATGCGGCGCGCGTGCTCGGCGCGGTGCAGCCGACGCTCACGCGCTACCGGTGGCCCGGCAACGTGCGCGAA
TTGCAGAACGTGATCGAGCGGATCGCGGTGGAGCTGGCCGACGCGGCCGACGAAGGCGATGCGGCCGCGCCCTGCGCGGC
GCTCGCGCCCGACGCGCTGCAGACGATCGCGCCCGAGCTGTTCGCCGCGCCGCCCGACGGCGGCGACGCCGAGGACGCGC
AGACGCTGCAGGCGCGCCGCCGCCGCGCGGAAGCGGACGAGATCCGTGCGGTGCTCGACGCCTGCGGCGGCGACCGCGAT
CGTGCGTGCGCGATGCTCGGCATCAGCAAGACGACGCTTTGGCGGAAGTTGTCCGCGAAATAA

Upstream 100 bases:

>100_bases
TGATTCTTAAGCGAACGGCGCCGCAGCCGGCGGCCCGTTTCATTTCAATTCGGAAATATCGTATTCCAAAAATGAAATCC
GGCGCGCATAATCGGCGGCC

Downstream 100 bases:

>100_bases
CGGCGAGTCGCACGACGTTGCGGGATGCCGCGGCGCTACGACGCGCCGGCACGCCGGCCGTCAGTCCGTCTTGTGATAGT
GGCGGTACGCCTTCGCGCGA

Product: propionate catabolism operon regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MDLSSIKPAGAADRTVRPRIWAMGISRLRDLFREIAGEFDERADVRIVTRAYEDALGAIAEAGTARPDVIVAAGSNGGFL
KTRAQVPVVVVSPTGFDVMQALARARRDATRIALVSAGDTPPEVRRFVAAYGLDVQFASYQTAQEAEACVHDLRDRGIET
IVGPGLVTDLAASAGMGAVFLYSHASVRRAVETALEVAYATHAEAFRRQRLDTLLQHLRDGVVALDAQGRVEAINERLAS
ALGVEPSAAVGRALVDLRPELRTLRGEDGDALATVRGVRYVVHRGPLVDRGVTSGSVLTFQESRAVERLDRALRSQPNTQ
QFAARYSLDDVVGASAPMTRVRELVRRYAKSDATVLVLGESGTGKEMIAQSLHALSARRSYPFVAVNCGAFPEALLESEL
FGYEEGAFTGARRGGKTGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVIRLGSTEPIRIDVRVIAATHRPLLAAV
EAGTFRADLYYRLNILNVGLPPLRERAADIPALAATLLVQAARREPRLAERLRDADDAARVLGAVQPTLTRYRWPGNVRE
LQNVIERIAVELADAADEGDAAAPCAALAPDALQTIAPELFAAPPDGGDAEDAQTLQARRRRAEADEIRAVLDACGGDRD
RACAMLGISKTTLWRKLSAK

Sequences:

>Translated_660_residues
MDLSSIKPAGAADRTVRPRIWAMGISRLRDLFREIAGEFDERADVRIVTRAYEDALGAIAEAGTARPDVIVAAGSNGGFL
KTRAQVPVVVVSPTGFDVMQALARARRDATRIALVSAGDTPPEVRRFVAAYGLDVQFASYQTAQEAEACVHDLRDRGIET
IVGPGLVTDLAASAGMGAVFLYSHASVRRAVETALEVAYATHAEAFRRQRLDTLLQHLRDGVVALDAQGRVEAINERLAS
ALGVEPSAAVGRALVDLRPELRTLRGEDGDALATVRGVRYVVHRGPLVDRGVTSGSVLTFQESRAVERLDRALRSQPNTQ
QFAARYSLDDVVGASAPMTRVRELVRRYAKSDATVLVLGESGTGKEMIAQSLHALSARRSYPFVAVNCGAFPEALLESEL
FGYEEGAFTGARRGGKTGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVIRLGSTEPIRIDVRVIAATHRPLLAAV
EAGTFRADLYYRLNILNVGLPPLRERAADIPALAATLLVQAARREPRLAERLRDADDAARVLGAVQPTLTRYRWPGNVRE
LQNVIERIAVELADAADEGDAAAPCAALAPDALQTIAPELFAAPPDGGDAEDAQTLQARRRRAEADEIRAVLDACGGDRD
RACAMLGISKTTLWRKLSAK
>Mature_660_residues
MDLSSIKPAGAADRTVRPRIWAMGISRLRDLFREIAGEFDERADVRIVTRAYEDALGAIAEAGTARPDVIVAAGSNGGFL
KTRAQVPVVVVSPTGFDVMQALARARRDATRIALVSAGDTPPEVRRFVAAYGLDVQFASYQTAQEAEACVHDLRDRGIET
IVGPGLVTDLAASAGMGAVFLYSHASVRRAVETALEVAYATHAEAFRRQRLDTLLQHLRDGVVALDAQGRVEAINERLAS
ALGVEPSAAVGRALVDLRPELRTLRGEDGDALATVRGVRYVVHRGPLVDRGVTSGSVLTFQESRAVERLDRALRSQPNTQ
QFAARYSLDDVVGASAPMTRVRELVRRYAKSDATVLVLGESGTGKEMIAQSLHALSARRSYPFVAVNCGAFPEALLESEL
FGYEEGAFTGARRGGKTGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVIRLGSTEPIRIDVRVIAATHRPLLAAV
EAGTFRADLYYRLNILNVGLPPLRERAADIPALAATLLVQAARREPRLAERLRDADDAARVLGAVQPTLTRYRWPGNVRE
LQNVIERIAVELADAADEGDAAAPCAALAPDALQTIAPELFAAPPDGGDAEDAQTLQARRRRAEADEIRAVLDACGGDRD
RACAMLGISKTTLWRKLSAK

Specific function: Involved In The Transcriptional Regulation Of The Propionate Catabolism Operon. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1786524, Length=344, Percent_Identity=47.6744186046512, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1789233, Length=368, Percent_Identity=37.7717391304348, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788550, Length=343, Percent_Identity=42.2740524781341, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1790437, Length=330, Percent_Identity=45.1515151515152, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1788905, Length=328, Percent_Identity=44.8170731707317, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI87082117, Length=266, Percent_Identity=48.4962406015038, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1789087, Length=281, Percent_Identity=48.3985765124555, Blast_Score=229, Evalue=5e-61,
Organism=Escherichia coli, GI1790299, Length=375, Percent_Identity=39.2, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI87082152, Length=250, Percent_Identity=45.6, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI87081872, Length=244, Percent_Identity=45.9016393442623, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1787583, Length=345, Percent_Identity=35.3623188405797, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI87081858, Length=465, Percent_Identity=31.1827956989247, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1789828, Length=239, Percent_Identity=36.4016736401674, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 71274; Mature: 71274

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSSIKPAGAADRTVRPRIWAMGISRLRDLFREIAGEFDERADVRIVTRAYEDALGAIA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHH
EAGTARPDVIVAAGSNGGFLKTRAQVPVVVVSPTGFDVMQALARARRDATRIALVSAGDT
HCCCCCCCEEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHCCHHEEEEEECCCC
PPEVRRFVAAYGLDVQFASYQTAQEAEACVHDLRDRGIETIVGPGLVTDLAASAGMGAVF
CHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCEEE
LYSHASVRRAVETALEVAYATHAEAFRRQRLDTLLQHLRDGVVALDAQGRVEAINERLAS
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHH
ALGVEPSAAVGRALVDLRPELRTLRGEDGDALATVRGVRYVVHRGPLVDRGVTSGSVLTF
HHCCCCHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
QESRAVERLDRALRSQPNTQQFAARYSLDDVVGASAPMTRVRELVRRYAKSDATVLVLGE
HHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECC
SGTGKEMIAQSLHALSARRSYPFVAVNCGAFPEALLESELFGYEEGAFTGARRGGKTGLF
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVIRLGSTEPIRIDVRVIAATHRPLLAAV
HHHCCCCEEHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEEEEEEECCCCHHHHH
EAGTFRADLYYRLNILNVGLPPLRERAADIPALAATLLVQAARREPRLAERLRDADDAAR
HCCCEEEEEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCHHHHHH
VLGAVQPTLTRYRWPGNVRELQNVIERIAVELADAADEGDAAAPCAALAPDALQTIAPEL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHH
FAAPPDGGDAEDAQTLQARRRRAEADEIRAVLDACGGDRDRACAMLGISKTTLWRKLSAK
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MDLSSIKPAGAADRTVRPRIWAMGISRLRDLFREIAGEFDERADVRIVTRAYEDALGAIA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHH
EAGTARPDVIVAAGSNGGFLKTRAQVPVVVVSPTGFDVMQALARARRDATRIALVSAGDT
HCCCCCCCEEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHCCHHEEEEEECCCC
PPEVRRFVAAYGLDVQFASYQTAQEAEACVHDLRDRGIETIVGPGLVTDLAASAGMGAVF
CHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCEEE
LYSHASVRRAVETALEVAYATHAEAFRRQRLDTLLQHLRDGVVALDAQGRVEAINERLAS
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHH
ALGVEPSAAVGRALVDLRPELRTLRGEDGDALATVRGVRYVVHRGPLVDRGVTSGSVLTF
HHCCCCHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
QESRAVERLDRALRSQPNTQQFAARYSLDDVVGASAPMTRVRELVRRYAKSDATVLVLGE
HHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECC
SGTGKEMIAQSLHALSARRSYPFVAVNCGAFPEALLESELFGYEEGAFTGARRGGKTGLF
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVIRLGSTEPIRIDVRVIAATHRPLLAAV
HHHCCCCEEHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEEEEEEECCCCHHHHH
EAGTFRADLYYRLNILNVGLPPLRERAADIPALAATLLVQAARREPRLAERLRDADDAAR
HCCCEEEEEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCHHHHHH
VLGAVQPTLTRYRWPGNVRELQNVIERIAVELADAADEGDAAAPCAALAPDALQTIAPEL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHH
FAAPPDGGDAEDAQTLQARRRRAEADEIRAVLDACGGDRDRACAMLGISKTTLWRKLSAK
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA