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The map label for this gene is manA [H]

Identifier: 189353978

GI number: 189353978

Start: 2298260

End: 2299369

Strand: Direct

Name: manA [H]

Synonym: BMULJ_05231

Alternate gene names: 189353978

Gene position: 2298260-2299369 (Clockwise)

Preceding gene: 189353973

Following gene: 189353980

Centisome position: 92.93

GC content: 71.17

Gene sequence:

>1110_bases
ATGTCCGTTTCCGACTCCGCATCCGCCCAGGCCGCCCAGTTGCGCCACCACTTCGCGCACGTCGTCTTGCCGATCTGGCG
AGGTTCAGGGTTCGACCATACATTACGTTTGCCGTTCGAGGCGGTCGATCCGGCCACGCATGCGCCGCTGCCCGTCACGC
GCTATCGCGCGATGGCCTGCGCGCGGCAGTTGTTCGTGTTCGCCCAGGCCGGCGATGCCGCGCACGCGGCCGTGCTGTTC
GACACGCTGCGCAGCCGCTTCCGCGACGCGCAGCACGGCGGCTGGTTCTACAGCGTCGATGCGCACGGCGCACCGCTCGA
CACGACGAAGGATCTGTACACGCACGCGTTCGTCGTCTTCGCGTGCGCCGCGTGGTATGCGGCATCGGGCGACGGCGACG
CGCGCACGGTTGCCGAGGAGACGGCCGCGCTGATTCAGGACCGCTTTGCGCCGCAGCCGGGCGACGCGCTGCTCGATGCC
GCGCGCGCGGCCGACTTCTCGTCGTCGGGCAGCGGCGCGCTGCAGAATCCGCTGATGCATCTCACCGAAGCGTGGCTCGC
GGCCGCCGACGCGTTCGGCGATACCGCATTCGACGATGCGCTCGCACGCACCGCGGCGGCCGTCGAGCGCACGTTCGTCG
ATCCGGCGACCGGCTGCGTCGCCGAACTGCCGCTCGGCGCGGCCGACAACCGTTTCGAGCCCGGCCATCAGTTCGAGTGG
TTTTATCTGGTCGATGCGGCCGGCGCGCGGCTCGCGCAAACGACGCTCCCCGAGGCGCTCACGCGCGCGTTTGCATTCGC
GGAACGACACGGCGTCGATCCGCAGACGGGCGGCGTCTGCGCGGCGCTCGACGCGCAAGGCACCTGCATCGACGGCACGC
AGCGGATCTGGGCGCAGACCGAATACCTGCGCGCGCTGGCGACGCACGGCGGCACGCCGGCGTCCGCGCCGCTCGCGACG
CAAATCGCGCGTTTCGCCGCGCGCTTCCTGCATCCGCGCGGCTGGTTCGAGTGCAAGACGGCCGACGGCCAGGTGTCGCG
CGCCGACATGCCGTCGACGACGCCGTACCACCTCGCGACCGCTTACGCGGCGCTGCCGACCGGCGCGTAA

Upstream 100 bases:

>100_bases
CTTTTTATGGTGCCGGCCGCGCGGAATGTTTTATCCTTGGGCCCGGTCGCGCCGATTCGGGCCGCGCCGACACGAATCGA
TCCCAGCGCACAACCCCGCC

Downstream 100 bases:

>100_bases
CGCGGCTCGGCGGCCGACGTCGCGACACGCGGCGCATACGCCCCGCGCGCGTCGCCGAGCTCGAAGACCGACACCGCGCG
CATCAGCTGCGCGGTCTGTT

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSVSDSASAQAAQLRHHFAHVVLPIWRGSGFDHTLRLPFEAVDPATHAPLPVTRYRAMACARQLFVFAQAGDAAHAAVLF
DTLRSRFRDAQHGGWFYSVDAHGAPLDTTKDLYTHAFVVFACAAWYAASGDGDARTVAEETAALIQDRFAPQPGDALLDA
ARAADFSSSGSGALQNPLMHLTEAWLAAADAFGDTAFDDALARTAAAVERTFVDPATGCVAELPLGAADNRFEPGHQFEW
FYLVDAAGARLAQTTLPEALTRAFAFAERHGVDPQTGGVCAALDAQGTCIDGTQRIWAQTEYLRALATHGGTPASAPLAT
QIARFAARFLHPRGWFECKTADGQVSRADMPSTTPYHLATAYAALPTGA

Sequences:

>Translated_369_residues
MSVSDSASAQAAQLRHHFAHVVLPIWRGSGFDHTLRLPFEAVDPATHAPLPVTRYRAMACARQLFVFAQAGDAAHAAVLF
DTLRSRFRDAQHGGWFYSVDAHGAPLDTTKDLYTHAFVVFACAAWYAASGDGDARTVAEETAALIQDRFAPQPGDALLDA
ARAADFSSSGSGALQNPLMHLTEAWLAAADAFGDTAFDDALARTAAAVERTFVDPATGCVAELPLGAADNRFEPGHQFEW
FYLVDAAGARLAQTTLPEALTRAFAFAERHGVDPQTGGVCAALDAQGTCIDGTQRIWAQTEYLRALATHGGTPASAPLAT
QIARFAARFLHPRGWFECKTADGQVSRADMPSTTPYHLATAYAALPTGA
>Mature_368_residues
SVSDSASAQAAQLRHHFAHVVLPIWRGSGFDHTLRLPFEAVDPATHAPLPVTRYRAMACARQLFVFAQAGDAAHAAVLFD
TLRSRFRDAQHGGWFYSVDAHGAPLDTTKDLYTHAFVVFACAAWYAASGDGDARTVAEETAALIQDRFAPQPGDALLDAA
RAADFSSSGSGALQNPLMHLTEAWLAAADAFGDTAFDDALARTAAAVERTFVDPATGCVAELPLGAADNRFEPGHQFEWF
YLVDAAGARLAQTTLPEALTRAFAFAERHGVDPQTGGVCAALDAQGTCIDGTQRIWAQTEYLRALATHGGTPASAPLATQ
IARFAARFLHPRGWFECKTADGQVSRADMPSTTPYHLATAYAALPTGA

Specific function: Unknown

COG id: COG2942

COG function: function code G; N-acyl-D-glucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acylglucosamine 2-epimerase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819 [H]

Pfam domain/function: PF07221 GlcNAc_2-epim [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 39290; Mature: 39159

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSDSASAQAAQLRHHFAHVVLPIWRGSGFDHTLRLPFEAVDPATHAPLPVTRYRAMAC
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCCCCCCCHHHHHHHHH
ARQLFVFAQAGDAAHAAVLFDTLRSRFRDAQHGGWFYSVDAHGAPLDTTKDLYTHAFVVF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
ACAAWYAASGDGDARTVAEETAALIQDRFAPQPGDALLDAARAADFSSSGSGALQNPLMH
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
LTEAWLAAADAFGDTAFDDALARTAAAVERTFVDPATGCVAELPLGAADNRFEPGHQFEW
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCEEE
FYLVDAAGARLAQTTLPEALTRAFAFAERHGVDPQTGGVCAALDAQGTCIDGTQRIWAQT
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEECCHHHHHHHH
EYLRALATHGGTPASAPLATQIARFAARFLHPRGWFECKTADGQVSRADMPSTTPYHLAT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHH
AYAALPTGA
HHHHCCCCC
>Mature Secondary Structure 
SVSDSASAQAAQLRHHFAHVVLPIWRGSGFDHTLRLPFEAVDPATHAPLPVTRYRAMAC
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCCCCCCCHHHHHHHHH
ARQLFVFAQAGDAAHAAVLFDTLRSRFRDAQHGGWFYSVDAHGAPLDTTKDLYTHAFVVF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
ACAAWYAASGDGDARTVAEETAALIQDRFAPQPGDALLDAARAADFSSSGSGALQNPLMH
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
LTEAWLAAADAFGDTAFDDALARTAAAVERTFVDPATGCVAELPLGAADNRFEPGHQFEW
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCEEE
FYLVDAAGARLAQTTLPEALTRAFAFAERHGVDPQTGGVCAALDAQGTCIDGTQRIWAQT
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEECCHHHHHHHH
EYLRALATHGGTPASAPLATQIARFAARFLHPRGWFECKTADGQVSRADMPSTTPYHLAT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHH
AYAALPTGA
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1452036; 11481430 [H]