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The map label for this gene is hemR [H]

Identifier: 189353935

GI number: 189353935

Start: 2250111

End: 2252378

Strand: Direct

Name: hemR [H]

Synonym: BMULJ_05188

Alternate gene names: 189353935

Gene position: 2250111-2252378 (Clockwise)

Preceding gene: 189353934

Following gene: 189353936

Centisome position: 90.98

GC content: 68.12

Gene sequence:

>2268_bases
GTGCATCGCTCTACGCTGGCGCGCCAGCCGATCTTTGCCGCGCTCATCGGCGCGGTCGGATTGTCCGCCGCCACGGCTCA
CGCCGATTCTTCGCCGTCCCACACCGCCGCCTCGTCCGTCACGGCCGACGCGGCAGCCGCACGCGCCAGCAGCGCGCTGC
TCGACCCGGTCACCGTCACGGCGACGCGCACCGCGACGGCCGCGAGCCGCACCGCCGCTTCCGTGTCGGTGATCGACGCG
GACGACCTCGACGAACAGCAGGCCACCAACATCAAGGACGCCTTGCGCTACGAGCCCGGCATCACGGTGCGGCGCACCGC
GTACCGTCCCGGCAACGCGGCGCTCGGCGGCGGCCGCGACGGCGATTCGAGCATCAACATCCGCGGCCTCGAAGGCAATC
GCGTGATGCTGATGGAAGACGGCATCCGCCTGCCGAACGCATTCTCGTTCGGCCCGCTCGAGGCGGGCCGCGGCGACTAC
ACCGATCTCGATACGCTGAAGCGCATCGAGATCGTGCGCGGGCCGGCGTCGGCGCTGTACGGCAGCGACGGACTGACCGG
TGCCGTCAACTTCATCACGAAGGATCCGCAGGACCTGCTGTCGATCTACCACAAGCCGACCTACTTCTCGTTCCGGCCGA
GCTACGATTCGACCGACCGCAGCATCGGCGCGACCGTGTCGGCCGCCGGCGGCAACGATCGCATCCAGGGGATGATCATC
GCCGACGGCCGCCGCGGTCACGAGATCGACACGCGCGGCAGCAACAACTCCGCAGGCAAGCTGCGCACGACGTCGAACCC
GCAGCACGTGTACAGCGAATCGCTGCTCGGCAAGCTCGTGCTGACGCCCACCGTGCGCGACACGATCAGGCTGACCGCCG
AAACCGTGCAGCGGCGCGTCGGCACCGACGTGCTATCTGCGATCGTCGCGCCCGCGACGCTCGGCCTCACGACGAGCGAC
CGGCTCGAACGCAACCGCTTCAGCGCCGATTACGCCTTTCACGACGACGCCTCGCGCTGGCTGCAGAACGCGCACGTGCA
GTTCTATTACCAGGAAGCGACGCAGGACCAGTACGCGTTCGAAACGCGCGGCACGCTGCCGTCACGCTCGCGCGACAACC
GCTACCGCGAACGCACGTTCGGCGGCTCCGCGTTCGCCGAAAGCGGATTCTCGACCGGCCCGCTTGCGCACAAGCTGCTG
GGCGGCGTCGACGGCAGCCTGTCGCGGATCACGAACCTGCGCGACGGCACGGTGCCCGGCGTCGGCGAGACGTTCCCGAA
CAAGGCCTTCCCCGACACCGACTACACGCTGTTCGGCGCGTTCGTGCAGGATCAGATCGGCTACGGCCGCCTGCTCGTCA
CGCCGGGGCTGCGCTTCGACACGTACCGGCTGAAGCCGTCGGGCAACGATCCGCTGTTCACCGGCCGCGCGGTGTCGACG
CACGCGAACGAACTGTCGCCGCGCGTCGCGGTGCTGTACGAGATCGCGCCTGCGCTGATTCCGTATCTGCAGTACGCACA
TGGATTCCGCGCGCCGACGCCCGATCAGGTCAACAGCAGCTTCTCGAATCCCGTGCAGGGCTATACCTCGATCGGCAATC
CGAACCTGAAGCCCGAGACCAGCGACACGTTCGAAGCCGGGCTGCGCGGGCGGGCCGGCACCGGCTACGGCACGATTCGC
TACAGCGCGGCCGCGTTCACCGGCCGCTACCGCAACTTCATCGCGCGTACGACGATCGCCGGCAGCGGCCGGCCGACCGA
TCCGTTCGTGTTCCAGTACGTGAACTTCGCCGATGCGCGCGTTCACGGCATCGAAGGCCGCGCCGACTGGGCGATGCCGA
ACGGCATCACGCTGCGCACCGCGCTCGCGCTGACGCGCGGCTCGACGCAAAACGACGGCGCCGCGAGCCAGCCGCTCAAC
ACCGTGAATCCGTTTTCTGCCGTGTTCGGCGTGCGCTACGAGCCGACCGAACGCTGGTTCGTGCAGACCGATCTGCTGTT
CCAGGCCGCGAAGCGCGACAAGGACATCGACCGGTCCGACTGTTCGAAGCGAGCCTGCTTCGCGCCGCCTTCGTCGTTTG
TCGTCGATCTGCGCGGCGGCTATCGCTTCAACAAGCACGTGAGCGCGACGGTCGGCATCCGCAACCTGTTCGACCGCAAG
TACTGGAACTGGTCCGACGTGCGCGGCATCGCCGCCGACTCGCCGGTGCTCGACGCCTATACGTCGCCCGGCCGTACCGT
CGCAGTCAGCATGAAGGTCGATTTCTGA

Upstream 100 bases:

>100_bases
CCTTTCAATTTGCCGTGCGCCGCATCGCGCGCATGGGCCAGCCAGGTGAACGCGTCGCCCAGCCAGCCTTCGGGCTTGTT
TCAACCATGGGAGACCACCT

Downstream 100 bases:

>100_bases
TGCGCGCCGGCTGCACGCGCGTCCCACCGTCCGTCAAGGAGTCCGACATGATGCAATCCCCCGTTTCCGCGTCGTCCGTG
CGCACGTCCACCTCGCTGCG

Product: iron complex outer membrane receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 755

Protein sequence:

>755_residues
MHRSTLARQPIFAALIGAVGLSAATAHADSSPSHTAASSVTADAAAARASSALLDPVTVTATRTATAASRTAASVSVIDA
DDLDEQQATNIKDALRYEPGITVRRTAYRPGNAALGGGRDGDSSINIRGLEGNRVMLMEDGIRLPNAFSFGPLEAGRGDY
TDLDTLKRIEIVRGPASALYGSDGLTGAVNFITKDPQDLLSIYHKPTYFSFRPSYDSTDRSIGATVSAAGGNDRIQGMII
ADGRRGHEIDTRGSNNSAGKLRTTSNPQHVYSESLLGKLVLTPTVRDTIRLTAETVQRRVGTDVLSAIVAPATLGLTTSD
RLERNRFSADYAFHDDASRWLQNAHVQFYYQEATQDQYAFETRGTLPSRSRDNRYRERTFGGSAFAESGFSTGPLAHKLL
GGVDGSLSRITNLRDGTVPGVGETFPNKAFPDTDYTLFGAFVQDQIGYGRLLVTPGLRFDTYRLKPSGNDPLFTGRAVST
HANELSPRVAVLYEIAPALIPYLQYAHGFRAPTPDQVNSSFSNPVQGYTSIGNPNLKPETSDTFEAGLRGRAGTGYGTIR
YSAAAFTGRYRNFIARTTIAGSGRPTDPFVFQYVNFADARVHGIEGRADWAMPNGITLRTALALTRGSTQNDGAASQPLN
TVNPFSAVFGVRYEPTERWFVQTDLLFQAAKRDKDIDRSDCSKRACFAPPSSFVVDLRGGYRFNKHVSATVGIRNLFDRK
YWNWSDVRGIAADSPVLDAYTSPGRTVAVSMKVDF

Sequences:

>Translated_755_residues
MHRSTLARQPIFAALIGAVGLSAATAHADSSPSHTAASSVTADAAAARASSALLDPVTVTATRTATAASRTAASVSVIDA
DDLDEQQATNIKDALRYEPGITVRRTAYRPGNAALGGGRDGDSSINIRGLEGNRVMLMEDGIRLPNAFSFGPLEAGRGDY
TDLDTLKRIEIVRGPASALYGSDGLTGAVNFITKDPQDLLSIYHKPTYFSFRPSYDSTDRSIGATVSAAGGNDRIQGMII
ADGRRGHEIDTRGSNNSAGKLRTTSNPQHVYSESLLGKLVLTPTVRDTIRLTAETVQRRVGTDVLSAIVAPATLGLTTSD
RLERNRFSADYAFHDDASRWLQNAHVQFYYQEATQDQYAFETRGTLPSRSRDNRYRERTFGGSAFAESGFSTGPLAHKLL
GGVDGSLSRITNLRDGTVPGVGETFPNKAFPDTDYTLFGAFVQDQIGYGRLLVTPGLRFDTYRLKPSGNDPLFTGRAVST
HANELSPRVAVLYEIAPALIPYLQYAHGFRAPTPDQVNSSFSNPVQGYTSIGNPNLKPETSDTFEAGLRGRAGTGYGTIR
YSAAAFTGRYRNFIARTTIAGSGRPTDPFVFQYVNFADARVHGIEGRADWAMPNGITLRTALALTRGSTQNDGAASQPLN
TVNPFSAVFGVRYEPTERWFVQTDLLFQAAKRDKDIDRSDCSKRACFAPPSSFVVDLRGGYRFNKHVSATVGIRNLFDRK
YWNWSDVRGIAADSPVLDAYTSPGRTVAVSMKVDF
>Mature_755_residues
MHRSTLARQPIFAALIGAVGLSAATAHADSSPSHTAASSVTADAAAARASSALLDPVTVTATRTATAASRTAASVSVIDA
DDLDEQQATNIKDALRYEPGITVRRTAYRPGNAALGGGRDGDSSINIRGLEGNRVMLMEDGIRLPNAFSFGPLEAGRGDY
TDLDTLKRIEIVRGPASALYGSDGLTGAVNFITKDPQDLLSIYHKPTYFSFRPSYDSTDRSIGATVSAAGGNDRIQGMII
ADGRRGHEIDTRGSNNSAGKLRTTSNPQHVYSESLLGKLVLTPTVRDTIRLTAETVQRRVGTDVLSAIVAPATLGLTTSD
RLERNRFSADYAFHDDASRWLQNAHVQFYYQEATQDQYAFETRGTLPSRSRDNRYRERTFGGSAFAESGFSTGPLAHKLL
GGVDGSLSRITNLRDGTVPGVGETFPNKAFPDTDYTLFGAFVQDQIGYGRLLVTPGLRFDTYRLKPSGNDPLFTGRAVST
HANELSPRVAVLYEIAPALIPYLQYAHGFRAPTPDQVNSSFSNPVQGYTSIGNPNLKPETSDTFEAGLRGRAGTGYGTIR
YSAAAFTGRYRNFIARTTIAGSGRPTDPFVFQYVNFADARVHGIEGRADWAMPNGITLRTALALTRGSTQNDGAASQPLN
TVNPFSAVFGVRYEPTERWFVQTDLLFQAAKRDKDIDRSDCSKRACFAPPSSFVVDLRGGYRFNKHVSATVGIRNLFDRK
YWNWSDVRGIAADSPVLDAYTSPGRTVAVSMKVDF

Specific function: This protein is involved in the initial step of iron uptake by binding hemin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=157, Percent_Identity=35.6687898089172, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788478, Length=140, Percent_Identity=33.5714285714286, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR011276
- InterPro:   IPR010949 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81687; Mature: 81687

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRSTLARQPIFAALIGAVGLSAATAHADSSPSHTAASSVTADAAAARASSALLDPVTVT
CCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
ATRTATAASRTAASVSVIDADDLDEQQATNIKDALRYEPGITVRRTAYRPGNAALGGGRD
EECCHHHHHHCCCEEEEEECCCCCHHHHCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
GDSSINIRGLEGNRVMLMEDGIRLPNAFSFGPLEAGRGDYTDLDTLKRIEIVRGPASALY
CCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCHHHHC
GSDGLTGAVNFITKDPQDLLSIYHKPTYFSFRPSYDSTDRSIGATVSAAGGNDRIQGMII
CCCCCCEEEHEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCCEEEEEE
ADGRRGHEIDTRGSNNSAGKLRTTSNPQHVYSESLLGKLVLTPTVRDTIRLTAETVQRRV
ECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHH
GTDVLSAIVAPATLGLTTSDRLERNRFSADYAFHDDASRWLQNAHVQFYYQEATQDQYAF
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCHHHHHHCCCEEEEEECCCCCCEEE
ETRGTLPSRSRDNRYRERTFGGSAFAESGFSTGPLAHKLLGGVDGSLSRITNLRDGTVPG
HHCCCCCCCCCCCHHHHHHCCCCHHHHCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCC
VGETFPNKAFPDTDYTLFGAFVQDQIGYGRLLVTPGLRFDTYRLKPSGNDPLFTGRAVST
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCEEECCCCCC
HANELSPRVAVLYEIAPALIPYLQYAHGFRAPTPDQVNSSFSNPVQGYTSIGNPNLKPET
CHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHCCCCCCCCCCC
SDTFEAGLRGRAGTGYGTIRYSAAAFTGRYRNFIARTTIAGSGRPTDPFVFQYVNFADAR
CHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHEEECCCCCCCCCHHEEECCCCCCE
VHGIEGRADWAMPNGITLRTALALTRGSTQNDGAASQPLNTVNPFSAVFGVRYEPTERWF
EECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCEECCCCCEE
VQTDLLFQAAKRDKDIDRSDCSKRACFAPPSSFVVDLRGGYRFNKHVSATVGIRNLFDRK
EEHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEEECCCCEEECCEEEEEHHHHHHHHCC
YWNWSDVRGIAADSPVLDAYTSPGRTVAVSMKVDF
CCCHHHCCCCCCCCCCCEEECCCCCEEEEEEEECC
>Mature Secondary Structure
MHRSTLARQPIFAALIGAVGLSAATAHADSSPSHTAASSVTADAAAARASSALLDPVTVT
CCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
ATRTATAASRTAASVSVIDADDLDEQQATNIKDALRYEPGITVRRTAYRPGNAALGGGRD
EECCHHHHHHCCCEEEEEECCCCCHHHHCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
GDSSINIRGLEGNRVMLMEDGIRLPNAFSFGPLEAGRGDYTDLDTLKRIEIVRGPASALY
CCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCHHHHC
GSDGLTGAVNFITKDPQDLLSIYHKPTYFSFRPSYDSTDRSIGATVSAAGGNDRIQGMII
CCCCCCEEEHEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCCEEEEEE
ADGRRGHEIDTRGSNNSAGKLRTTSNPQHVYSESLLGKLVLTPTVRDTIRLTAETVQRRV
ECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHH
GTDVLSAIVAPATLGLTTSDRLERNRFSADYAFHDDASRWLQNAHVQFYYQEATQDQYAF
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCHHHHHHCCCEEEEEECCCCCCEEE
ETRGTLPSRSRDNRYRERTFGGSAFAESGFSTGPLAHKLLGGVDGSLSRITNLRDGTVPG
HHCCCCCCCCCCCHHHHHHCCCCHHHHCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCC
VGETFPNKAFPDTDYTLFGAFVQDQIGYGRLLVTPGLRFDTYRLKPSGNDPLFTGRAVST
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCEEECCCCCC
HANELSPRVAVLYEIAPALIPYLQYAHGFRAPTPDQVNSSFSNPVQGYTSIGNPNLKPET
CHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHCCCCCCCCCCC
SDTFEAGLRGRAGTGYGTIRYSAAAFTGRYRNFIARTTIAGSGRPTDPFVFQYVNFADAR
CHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHEEECCCCCCCCCHHEEECCCCCCE
VHGIEGRADWAMPNGITLRTALALTRGSTQNDGAASQPLNTVNPFSAVFGVRYEPTERWF
EECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCEECCCCCEE
VQTDLLFQAAKRDKDIDRSDCSKRACFAPPSSFVVDLRGGYRFNKHVSATVGIRNLFDRK
EEHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEEECCCCEEECCEEEEEHHHHHHHHCC
YWNWSDVRGIAADSPVLDAYTSPGRTVAVSMKVDF
CCCHHHCCCCCCCCCCCEEECCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1425573 [H]