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The map label for this gene is dapA [C]

Identifier: 189353868

GI number: 189353868

Start: 2174213

End: 2175127

Strand: Direct

Name: dapA [C]

Synonym: BMULJ_05120

Alternate gene names: 189353868

Gene position: 2174213-2175127 (Clockwise)

Preceding gene: 189353863

Following gene: 189353871

Centisome position: 87.91

GC content: 65.36

Gene sequence:

>915_bases
ATGACCTCACCGCAAGAACTCAAACAGATCATTTCCCACGGCCTGCTGTCGTTTCCGCTGACGGACTTCGACGCCGACGG
CAGCTTCCGCCCGACCACGTACGCCGAGCGTCTGGAATGGCTTGCGCCGTATGGCGCGAGCGCGCTGTTCGCCGCCGGCG
GCACCGGCGAATTCTTCTCGCTCACGCAGCGCGAGTATTCGGACGTGATCCGCGTCGCGACCGAAACCTGCAAGGGCAAG
GTGCCGATCCTCGCCGGTGCGGGCGGCGCGACGCGCGTCGCGATCGAATATGCGCAGGAAGCCGAGCGCCTCGGCGCGAG
CGGCGTGCTGCTGATGCCGCACTATCTGACCGAAGCGAGCCAGGAAGGGATTGCCGAGCACGTCGAGCAGGTGTGCCGCG
CGCTGAAGATCGGCGTCGTCGTGTACAACCGCGCGAATTCGAAGCTCAATGCGGACATGCTCGAACGCCTCGCCGATCGC
TGCCCGAACCTGATCGGCTTCAAGGACGGCGTCGGCGACATCGAAAGCATGGTCACGATCCGCCGCCGCCTCGGCGAGCG
TTTCGCGTATCTCGGCGGCCTGCCGACGGCCGAAGTCTATGCGGCCGCGTACAAGGCGCTCGGCGTGCCGGTGTATTCGT
CGGCCGTGTTCAACTTCATCCCGAAGACGGCGATGACGTTCTACGAAGCGATCGCGAAGGACGATCACGCGACCGTCGGC
CGCCTGATCGACGAGTTCTTCCTGCCGTATCTGAAGATCCGCAACCGCCGCGCGGGCTATGCGGTCAGCATCGTGAAGGC
CGGCGCGAAGCTGGTCGGCCACGATGCGGGCCCGGTGCGCGCGCCGCTCGTCGATCTGACCGAAGAAGAAGTCGCGCAGC
TCGATGTGCTGATCAAGAAGATGGGCCCGCAGTAA

Upstream 100 bases:

>100_bases
CGGTTCTTGCGTTGTACGATGACATACAACGACATCGCCACTATGGCTCGTATGCCGTTCCCGACGAACCCAGCACTCGC
GCTAGACGGACGACCCAACC

Downstream 100 bases:

>100_bases
AAACGACGCGGCCGGCGGCGGCGCCATCGCGGCGCAGCGGCCGGCCCGCTCGCATCGACGCGGCCGCGCGGCTCGAAGCG
CCGGCGCAGCCGTCACATCC

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTSPQELKQIISHGLLSFPLTDFDADGSFRPTTYAERLEWLAPYGASALFAAGGTGEFFSLTQREYSDVIRVATETCKGK
VPILAGAGGATRVAIEYAQEAERLGASGVLLMPHYLTEASQEGIAEHVEQVCRALKIGVVVYNRANSKLNADMLERLADR
CPNLIGFKDGVGDIESMVTIRRRLGERFAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMTFYEAIAKDDHATVG
RLIDEFFLPYLKIRNRRAGYAVSIVKAGAKLVGHDAGPVRAPLVDLTEEEVAQLDVLIKKMGPQ

Sequences:

>Translated_304_residues
MTSPQELKQIISHGLLSFPLTDFDADGSFRPTTYAERLEWLAPYGASALFAAGGTGEFFSLTQREYSDVIRVATETCKGK
VPILAGAGGATRVAIEYAQEAERLGASGVLLMPHYLTEASQEGIAEHVEQVCRALKIGVVVYNRANSKLNADMLERLADR
CPNLIGFKDGVGDIESMVTIRRRLGERFAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMTFYEAIAKDDHATVG
RLIDEFFLPYLKIRNRRAGYAVSIVKAGAKLVGHDAGPVRAPLVDLTEEEVAQLDVLIKKMGPQ
>Mature_303_residues
TSPQELKQIISHGLLSFPLTDFDADGSFRPTTYAERLEWLAPYGASALFAAGGTGEFFSLTQREYSDVIRVATETCKGKV
PILAGAGGATRVAIEYAQEAERLGASGVLLMPHYLTEASQEGIAEHVEQVCRALKIGVVVYNRANSKLNADMLERLADRC
PNLIGFKDGVGDIESMVTIRRRLGERFAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMTFYEAIAKDDHATVGR
LIDEFFLPYLKIRNRRAGYAVSIVKAGAKLVGHDAGPVRAPLVDLTEEEVAQLDVLIKKMGPQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=234, Percent_Identity=25.6410256410256, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786463, Length=224, Percent_Identity=29.0178571428571, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87082415, Length=298, Percent_Identity=25.1677852348993, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.41 [H]

Molecular weight: Translated: 33038; Mature: 32907

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPQELKQIISHGLLSFPLTDFDADGSFRPTTYAERLEWLAPYGASALFAAGGTGEFFS
CCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCHHHH
LTQREYSDVIRVATETCKGKVPILAGAGGATRVAIEYAQEAERLGASGVLLMPHYLTEAS
HHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
QEGIAEHVEQVCRALKIGVVVYNRANSKLNADMLERLADRCPNLIGFKDGVGDIESMVTI
HHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RRRLGERFAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMTFYEAIAKDDHATVG
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLIDEFFLPYLKIRNRRAGYAVSIVKAGAKLVGHDAGPVRAPLVDLTEEEVAQLDVLIKK
HHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHH
MGPQ
HCCC
>Mature Secondary Structure 
TSPQELKQIISHGLLSFPLTDFDADGSFRPTTYAERLEWLAPYGASALFAAGGTGEFFS
CCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCHHHH
LTQREYSDVIRVATETCKGKVPILAGAGGATRVAIEYAQEAERLGASGVLLMPHYLTEAS
HHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
QEGIAEHVEQVCRALKIGVVVYNRANSKLNADMLERLADRCPNLIGFKDGVGDIESMVTI
HHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RRRLGERFAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMTFYEAIAKDDHATVG
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLIDEFFLPYLKIRNRRAGYAVSIVKAGAKLVGHDAGPVRAPLVDLTEEEVAQLDVLIKK
HHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHH
MGPQ
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA