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The map label for this gene is lgrD [H]

Identifier: 189353754

GI number: 189353754

Start: 2032560

End: 2035547

Strand: Direct

Name: lgrD [H]

Synonym: BMULJ_05001

Alternate gene names: 189353754

Gene position: 2032560-2035547 (Clockwise)

Preceding gene: 189353753

Following gene: 189353757

Centisome position: 82.18

GC content: 67.97

Gene sequence:

>2988_bases
ATGGGAATTGAAACAGTCGAGTCGACCGTTCTGCACGCCTTTGCTGCACGCGCAGCAGAAGCGCCGAATCGCACCGCGGT
TCTCTCGCGCGATGCATCGCTGACCTACGGCGAACTGGACGCGCGCAGCAATCGCGTCGCGCGGGCGCTGATCGCACGCG
GCGTCGCGCCGGGCAGCCTCGTCCCGGTCGAAGCCGTGCGCTCCGCCGATTTCCTCGTGGCACTGCTCGGCGTGCTGAAG
GCCGGCGCCGCCTACATTCCGATCGACGATGCGTATCCGGCGGAGCGCAAACGCCACATCTACGAACAAAGCGGTGCGAC
CGTCGCGCTCCACGCGCGCGCCAATGCGGCCGCCGAACCGTCGAGCGCGGGCGTCGCGCCGCTCGCGGTCGCGTCGCTGA
TCGGCGACGATGCGCCCGACGGCGAGTTGCGCACACCGGCGCCGCACGATCTGCTCTACGTGATTTTCACGTCGGGCACG
ACCGGCCGGCCGAAGGGCGTCGAAATCGAGCATCATGCGGTCGCGCGGCTAGTCGACTGGCACAACCGGCAGTTCGGCGT
GACGGCCGCGAGCCGGATGCCGCTAATGGCAGGGCTGAGTTTCGACATCTCGCAGTGGGAGATCTGGTCGGCACTGACGG
CCGGCGCGACGCTGCTGTTGCCCGACGAAGAGATCCGCCCCGACGCCGATGCGCTGGTCGCGTTTCATCGCGACCATGCG
ACCACGCACGCGTTCGTCCCGACCGTGATGGTGCCCGACTTCGTGCGCGCCTCGCGCGGCAGCGATCTGGCGCTGCGCTA
CCTGTTCACGGCCGGCGAAAAGCTGCAGCCGGTCGACACCGACGGCACGACCTACACGCTGATCGATTTCTACGGACCGA
CCGAGACGACGATCTTCGCGACGATGCATCGCGTGCCGCGCGCGACGCTCGGCCGCCCTTCGTCGATCGGTCATCCGGTG
CCCGGCGCGACGATCCATGTGCTCGACGCACAGCTCGCGCCGCTGCCCGACGGCCAGGTCGGCGAGCTCTGCATCGCGGG
CCCGTGCGTCGCGCGCGGCTATCTGAACGACCCGTCGCTCACGCACGACAAGTTCGTCGCGCTGCCGCACGATCGCTCGC
AGCGGCTGTACCGCACCGGCGATCTCGGACGCCGGCTGCCCGACGGCACGATCCAGTATCTCGGCCGCATGGACGATCAG
TTGAAGATCCGCGGCCACCGTGTCGAGCTCGGCGAGATCGCGTCGGTGCTGTCGACGCAGCCCGGCATCCGCAAGTGCGC
GGTGATTGCCGTCGAGGACGCGTCGAATGCGAAGGAGATCGTCGCGTTCGTCGTGCCCGACGCCGAGCACGCGAACGGCG
ACGTGATCGGCTCGATCCGCACGCGGATCCGCGCGTGCCTGCCGCACTACATGCGTCCGCGCCGCTACGTCGTGCTGCCC
GAGCTTCCCGTCACGCTGAACGGCAAGGTCGACAAGGCCGCGCTGCGCGAACTCGACGACGGCAGCGCGGCGCGCGCATC
GCACGCGGGCTGGCGCGACGACCGCATCGACACCGCGATCGCGCGGACGCTCGCACCGATCCTCGGTCATACCGATTTCG
GGCCGGCCGACAATTTCTTCGACATCGGCGGCCACTCGCTGCTGATCGCGGAGTTCGTGCGCCGCCTCGGCGAAACGTTG
CGGATGAAGGTCTACGTGCGCGACGTGTACGAGTGTCCGACGGGCGCCGCGCTGCGCGAGCGCCTCGAAGCGCGGCTCAA
CGAGCGGCAGTCGCTGCTCGATGCGGAGCCGGCGCGCGCGCTGCGCGACGACATCGCGCTGCCGGACGGCATCGCGTCGT
TCCGCCCGTTCGATACGCGCCGGCTCGAACGGCCCGCGCATATCTTGCTGACGGGCGCGACGGGCTTCGTCGGCGTGCAT
CTGCTGGCCGATCTGCTCGAGCGCACCGACGCGGTCGTGCACTGTACGGTGCGCGCGGCCGACGGCGCATCCGCCCGCGC
GCGGATCGTCGAACAGGCGCAGCGCTATCGCGTCGCGCTGCCCGACTCGTCGCGCTGGGTCGCACATGCGGCCGACCTGT
CGCTGCCGCGGCTCGGCATGAGCGATGCCGATTACCGCACGCTGGCGGGCTGCGTCGATGTGATCTATCACTCGGCGAGC
GCGGTCAACTTCATTCAGCCGTATTCGTACATGCGCACCGACAACGTCGACGGGCTCAAGCGCGTGCTCGCGTTCGCGGC
GGACGGCCAGCCGAAGGCGCTCATGCTGCTGTCGACGATTTCGGTCTACAGCTGGGGCCATCTGCACACCGGCAAGACGA
CGGTGTCCGAAGACGACGACATCGATCAGAACCTGCCGGCCGTGATGACGGACATCGGCTACGTGCGCAGCAAATGGGTG
ATGGAGAAAGTGGCCGATCTCGCGGCGTCGCGCGGGTTGCCGCTGATGACGTTCCGCCTCGGCTACGCGACGTTCCATCG
CGACACGGGGCTCAGCGCGAACTATCAGTGGTGGGGCCGGCTCGTGCGCACCTGCATCGACCAGCAGCAGATTCCCGATC
TGCGCAATCTGCGCGAAGGGCTGACGACGGTCGATTACATGACGCATGCGATCGCGCATATTTCGCGCAATCCGTCGGCG
CTCGGCCACAAGTACAACCTCGTGCATACCGACGACAACAACCTGACGCTCCGGCAGTTCTTCGAGCGCCTCGAACGGCA
TTTCGGATTGCGCTTCGAGACCGTGCCGTTCCGTCAATGGCTCGACGGCTGGCAGCACGACACGGCCGCGCCGCTCTATC
CGCTGCTGAGCCTGTTCCGCGACGTGATGTACGACGGACGCTCCACCGTCGAGCTCTATCAGGACACGTACCGGTGGCGC
TGCGACCGCGTGCAGGCGGCACTACAGGGCAGCGGCATCGAGGAGCCGACGTTTACGCGCGACGAACTCGCGCGCTATCT
GACGCAGTCGATCGGCCATCGCGTGTAA

Upstream 100 bases:

>100_bases
GCAGTGATCGTCTATTGGACGATCATTTGCCCGCTATTTACCCAACGATTTTTCATCCGTATTTGAAACTCGCTCACCGC
AGTATCAAAGGAGGATTTTC

Downstream 100 bases:

>100_bases
CACACGGCACGACCGCCGCAGCACGCACGATCGCGCGAGCGGTCGTGCGTGCGCGTCTACGGTGCACTCATTGCGCGCGA
TGTTCCCACGTCCCTTCGAC

Product: non-ribosomal peptide synthetase module protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 995; Mature: 994

Protein sequence:

>995_residues
MGIETVESTVLHAFAARAAEAPNRTAVLSRDASLTYGELDARSNRVARALIARGVAPGSLVPVEAVRSADFLVALLGVLK
AGAAYIPIDDAYPAERKRHIYEQSGATVALHARANAAAEPSSAGVAPLAVASLIGDDAPDGELRTPAPHDLLYVIFTSGT
TGRPKGVEIEHHAVARLVDWHNRQFGVTAASRMPLMAGLSFDISQWEIWSALTAGATLLLPDEEIRPDADALVAFHRDHA
TTHAFVPTVMVPDFVRASRGSDLALRYLFTAGEKLQPVDTDGTTYTLIDFYGPTETTIFATMHRVPRATLGRPSSIGHPV
PGATIHVLDAQLAPLPDGQVGELCIAGPCVARGYLNDPSLTHDKFVALPHDRSQRLYRTGDLGRRLPDGTIQYLGRMDDQ
LKIRGHRVELGEIASVLSTQPGIRKCAVIAVEDASNAKEIVAFVVPDAEHANGDVIGSIRTRIRACLPHYMRPRRYVVLP
ELPVTLNGKVDKAALRELDDGSAARASHAGWRDDRIDTAIARTLAPILGHTDFGPADNFFDIGGHSLLIAEFVRRLGETL
RMKVYVRDVYECPTGAALRERLEARLNERQSLLDAEPARALRDDIALPDGIASFRPFDTRRLERPAHILLTGATGFVGVH
LLADLLERTDAVVHCTVRAADGASARARIVEQAQRYRVALPDSSRWVAHAADLSLPRLGMSDADYRTLAGCVDVIYHSAS
AVNFIQPYSYMRTDNVDGLKRVLAFAADGQPKALMLLSTISVYSWGHLHTGKTTVSEDDDIDQNLPAVMTDIGYVRSKWV
MEKVADLAASRGLPLMTFRLGYATFHRDTGLSANYQWWGRLVRTCIDQQQIPDLRNLREGLTTVDYMTHAIAHISRNPSA
LGHKYNLVHTDDNNLTLRQFFERLERHFGLRFETVPFRQWLDGWQHDTAAPLYPLLSLFRDVMYDGRSTVELYQDTYRWR
CDRVQAALQGSGIEEPTFTRDELARYLTQSIGHRV

Sequences:

>Translated_995_residues
MGIETVESTVLHAFAARAAEAPNRTAVLSRDASLTYGELDARSNRVARALIARGVAPGSLVPVEAVRSADFLVALLGVLK
AGAAYIPIDDAYPAERKRHIYEQSGATVALHARANAAAEPSSAGVAPLAVASLIGDDAPDGELRTPAPHDLLYVIFTSGT
TGRPKGVEIEHHAVARLVDWHNRQFGVTAASRMPLMAGLSFDISQWEIWSALTAGATLLLPDEEIRPDADALVAFHRDHA
TTHAFVPTVMVPDFVRASRGSDLALRYLFTAGEKLQPVDTDGTTYTLIDFYGPTETTIFATMHRVPRATLGRPSSIGHPV
PGATIHVLDAQLAPLPDGQVGELCIAGPCVARGYLNDPSLTHDKFVALPHDRSQRLYRTGDLGRRLPDGTIQYLGRMDDQ
LKIRGHRVELGEIASVLSTQPGIRKCAVIAVEDASNAKEIVAFVVPDAEHANGDVIGSIRTRIRACLPHYMRPRRYVVLP
ELPVTLNGKVDKAALRELDDGSAARASHAGWRDDRIDTAIARTLAPILGHTDFGPADNFFDIGGHSLLIAEFVRRLGETL
RMKVYVRDVYECPTGAALRERLEARLNERQSLLDAEPARALRDDIALPDGIASFRPFDTRRLERPAHILLTGATGFVGVH
LLADLLERTDAVVHCTVRAADGASARARIVEQAQRYRVALPDSSRWVAHAADLSLPRLGMSDADYRTLAGCVDVIYHSAS
AVNFIQPYSYMRTDNVDGLKRVLAFAADGQPKALMLLSTISVYSWGHLHTGKTTVSEDDDIDQNLPAVMTDIGYVRSKWV
MEKVADLAASRGLPLMTFRLGYATFHRDTGLSANYQWWGRLVRTCIDQQQIPDLRNLREGLTTVDYMTHAIAHISRNPSA
LGHKYNLVHTDDNNLTLRQFFERLERHFGLRFETVPFRQWLDGWQHDTAAPLYPLLSLFRDVMYDGRSTVELYQDTYRWR
CDRVQAALQGSGIEEPTFTRDELARYLTQSIGHRV
>Mature_994_residues
GIETVESTVLHAFAARAAEAPNRTAVLSRDASLTYGELDARSNRVARALIARGVAPGSLVPVEAVRSADFLVALLGVLKA
GAAYIPIDDAYPAERKRHIYEQSGATVALHARANAAAEPSSAGVAPLAVASLIGDDAPDGELRTPAPHDLLYVIFTSGTT
GRPKGVEIEHHAVARLVDWHNRQFGVTAASRMPLMAGLSFDISQWEIWSALTAGATLLLPDEEIRPDADALVAFHRDHAT
THAFVPTVMVPDFVRASRGSDLALRYLFTAGEKLQPVDTDGTTYTLIDFYGPTETTIFATMHRVPRATLGRPSSIGHPVP
GATIHVLDAQLAPLPDGQVGELCIAGPCVARGYLNDPSLTHDKFVALPHDRSQRLYRTGDLGRRLPDGTIQYLGRMDDQL
KIRGHRVELGEIASVLSTQPGIRKCAVIAVEDASNAKEIVAFVVPDAEHANGDVIGSIRTRIRACLPHYMRPRRYVVLPE
LPVTLNGKVDKAALRELDDGSAARASHAGWRDDRIDTAIARTLAPILGHTDFGPADNFFDIGGHSLLIAEFVRRLGETLR
MKVYVRDVYECPTGAALRERLEARLNERQSLLDAEPARALRDDIALPDGIASFRPFDTRRLERPAHILLTGATGFVGVHL
LADLLERTDAVVHCTVRAADGASARARIVEQAQRYRVALPDSSRWVAHAADLSLPRLGMSDADYRTLAGCVDVIYHSASA
VNFIQPYSYMRTDNVDGLKRVLAFAADGQPKALMLLSTISVYSWGHLHTGKTTVSEDDDIDQNLPAVMTDIGYVRSKWVM
EKVADLAASRGLPLMTFRLGYATFHRDTGLSANYQWWGRLVRTCIDQQQIPDLRNLREGLTTVDYMTHAIAHISRNPSAL
GHKYNLVHTDDNNLTLRQFFERLERHFGLRFETVPFRQWLDGWQHDTAAPLYPLLSLFRDVMYDGRSTVELYQDTYRWRC
DRVQAALQGSGIEEPTFTRDELARYLTQSIGHRV

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=548, Percent_Identity=23.5401459854015, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI45580730, Length=368, Percent_Identity=27.445652173913, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI38505220, Length=507, Percent_Identity=23.2741617357002, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI115511026, Length=506, Percent_Identity=22.7272727272727, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI42544132, Length=369, Percent_Identity=25.4742547425474, Blast_Score=97, Evalue=9e-20,
Organism=Homo sapiens, GI187761345, Length=540, Percent_Identity=24.8148148148148, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI187761343, Length=540, Percent_Identity=24.8148148148148, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI157311624, Length=522, Percent_Identity=22.6053639846743, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI157311622, Length=522, Percent_Identity=22.6053639846743, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI58082049, Length=522, Percent_Identity=22.4137931034483, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI13375727, Length=548, Percent_Identity=22.4452554744526, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI28416953, Length=383, Percent_Identity=25.5874673629243, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI122937307, Length=247, Percent_Identity=25.5060728744939, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI8923896, Length=368, Percent_Identity=22.8260869565217, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1786801, Length=609, Percent_Identity=32.512315270936, Blast_Score=254, Evalue=2e-68,
Organism=Escherichia coli, GI145693145, Length=519, Percent_Identity=24.6628131021195, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1790505, Length=553, Percent_Identity=24.4122965641953, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786810, Length=515, Percent_Identity=25.631067961165, Blast_Score=90, Evalue=9e-19,
Organism=Escherichia coli, GI221142682, Length=501, Percent_Identity=23.3532934131737, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786529, Length=378, Percent_Identity=27.5132275132275, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1788107, Length=546, Percent_Identity=21.7948717948718, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17556356, Length=562, Percent_Identity=25.9786476868327, Blast_Score=137, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17550940, Length=429, Percent_Identity=24.4755244755245, Blast_Score=110, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17538037, Length=553, Percent_Identity=23.869801084991, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17557194, Length=539, Percent_Identity=22.0779220779221, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17560308, Length=532, Percent_Identity=23.3082706766917, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994690, Length=377, Percent_Identity=24.9336870026525, Blast_Score=90, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994694, Length=377, Percent_Identity=24.9336870026525, Blast_Score=90, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994703, Length=547, Percent_Identity=21.3893967093236, Blast_Score=90, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71985884, Length=384, Percent_Identity=26.0416666666667, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71982997, Length=387, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983001, Length=387, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559526, Length=379, Percent_Identity=23.2189973614776, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25147511, Length=168, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17556552, Length=166, Percent_Identity=31.3253012048193, Blast_Score=68, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1081, Percent_Identity=26.4569842738205, Blast_Score=280, Evalue=8e-76,
Organism=Saccharomyces cerevisiae, GI6319264, Length=386, Percent_Identity=23.0569948186528, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319699, Length=360, Percent_Identity=22.5, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323182, Length=582, Percent_Identity=22.5085910652921, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648676, Length=671, Percent_Identity=27.7198211624441, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24581924, Length=364, Percent_Identity=27.1978021978022, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24582852, Length=375, Percent_Identity=25.0666666666667, Blast_Score=94, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24667955, Length=369, Percent_Identity=22.7642276422764, Blast_Score=83, Evalue=9e-16,
Organism=Drosophila melanogaster, GI62472339, Length=369, Percent_Identity=22.7642276422764, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667959, Length=369, Percent_Identity=22.7642276422764, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62471679, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62471683, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62471685, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24586636, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62471681, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62471687, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24586634, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI22026970, Length=177, Percent_Identity=31.638418079096, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62471689, Length=174, Percent_Identity=32.183908045977, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 109650; Mature: 109518

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIETVESTVLHAFAARAAEAPNRTAVLSRDASLTYGELDARSNRVARALIARGVAPGSL
CCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VPVEAVRSADFLVALLGVLKAGAAYIPIDDAYPAERKRHIYEQSGATVALHARANAAAEP
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
SSAGVAPLAVASLIGDDAPDGELRTPAPHDLLYVIFTSGTTGRPKGVEIEHHAVARLVDW
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHH
HNRQFGVTAASRMPLMAGLSFDISQWEIWSALTAGATLLLPDEEIRPDADALVAFHRDHA
CCCEECCCHHHCCCEEECCCCCCCHHHHHHHHHCCEEEEECCHHCCCCHHHHHEECCCCC
TTHAFVPTVMVPDFVRASRGSDLALRYLFTAGEKLQPVDTDGTTYTLIDFYGPTETTIFA
CHHHHCCHHHHHHHHHHCCCCCCEEHEEHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHH
TMHRVPRATLGRPSSIGHPVPGATIHVLDAQLAPLPDGQVGELCIAGPCVARGYLNDPSL
HHHHCCHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCHHHCCCCCCCCC
THDKFVALPHDRSQRLYRTGDLGRRLPDGTIQYLGRMDDQLKIRGHRVELGEIASVLSTQ
CCCCEEECCCCCCHHHHHCCCHHCCCCCHHHHHHHCCCCCEEEECCEECHHHHHHHHHCC
PGIRKCAVIAVEDASNAKEIVAFVVPDAEHANGDVIGSIRTRIRACLPHYMRPRRYVVLP
CCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
ELPVTLNGKVDKAALRELDDGSAARASHAGWRDDRIDTAIARTLAPILGHTDFGPADNFF
CCCEEECCCCCHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEE
DIGGHSLLIAEFVRRLGETLRMKVYVRDVYECPTGAALRERLEARLNERQSLLDAEPARA
ECCCCHHHHHHHHHHHHHHHEEHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
LRDDIALPDGIASFRPFDTRRLERPAHILLTGATGFVGVHLLADLLERTDAVVHCTVRAA
HHHHCCCCCCCHHCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEC
DGASARARIVEQAQRYRVALPDSSRWVAHAADLSLPRLGMSDADYRTLAGCVDVIYHSAS
CCCHHHHHHHHHHHHCEEECCCCCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
AVNFIQPYSYMRTDNVDGLKRVLAFAADGQPKALMLLSTISVYSWGHLHTGKTTVSEDDD
HHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCEECCCCCCCCCCC
IDQNLPAVMTDIGYVRSKWVMEKVADLAASRGLPLMTFRLGYATFHRDTGLSANYQWWGR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHEECCCCCCCCHHHHHH
LVRTCIDQQQIPDLRNLREGLTTVDYMTHAIAHISRNPSALGHKYNLVHTDDNNLTLRQF
HHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEEECCCCCHHHHH
FERLERHFGLRFETVPFRQWLDGWQHDTAAPLYPLLSLFRDVMYDGRSTVELYQDTYRWR
HHHHHHHHCCEEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
CDRVQAALQGSGIEEPTFTRDELARYLTQSIGHRV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GIETVESTVLHAFAARAAEAPNRTAVLSRDASLTYGELDARSNRVARALIARGVAPGSL
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VPVEAVRSADFLVALLGVLKAGAAYIPIDDAYPAERKRHIYEQSGATVALHARANAAAEP
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
SSAGVAPLAVASLIGDDAPDGELRTPAPHDLLYVIFTSGTTGRPKGVEIEHHAVARLVDW
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHH
HNRQFGVTAASRMPLMAGLSFDISQWEIWSALTAGATLLLPDEEIRPDADALVAFHRDHA
CCCEECCCHHHCCCEEECCCCCCCHHHHHHHHHCCEEEEECCHHCCCCHHHHHEECCCCC
TTHAFVPTVMVPDFVRASRGSDLALRYLFTAGEKLQPVDTDGTTYTLIDFYGPTETTIFA
CHHHHCCHHHHHHHHHHCCCCCCEEHEEHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHH
TMHRVPRATLGRPSSIGHPVPGATIHVLDAQLAPLPDGQVGELCIAGPCVARGYLNDPSL
HHHHCCHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCHHHCCCCCCCCC
THDKFVALPHDRSQRLYRTGDLGRRLPDGTIQYLGRMDDQLKIRGHRVELGEIASVLSTQ
CCCCEEECCCCCCHHHHHCCCHHCCCCCHHHHHHHCCCCCEEEECCEECHHHHHHHHHCC
PGIRKCAVIAVEDASNAKEIVAFVVPDAEHANGDVIGSIRTRIRACLPHYMRPRRYVVLP
CCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
ELPVTLNGKVDKAALRELDDGSAARASHAGWRDDRIDTAIARTLAPILGHTDFGPADNFF
CCCEEECCCCCHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEE
DIGGHSLLIAEFVRRLGETLRMKVYVRDVYECPTGAALRERLEARLNERQSLLDAEPARA
ECCCCHHHHHHHHHHHHHHHEEHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
LRDDIALPDGIASFRPFDTRRLERPAHILLTGATGFVGVHLLADLLERTDAVVHCTVRAA
HHHHCCCCCCCHHCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEC
DGASARARIVEQAQRYRVALPDSSRWVAHAADLSLPRLGMSDADYRTLAGCVDVIYHSAS
CCCHHHHHHHHHHHHCEEECCCCCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
AVNFIQPYSYMRTDNVDGLKRVLAFAADGQPKALMLLSTISVYSWGHLHTGKTTVSEDDD
HHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCEECCCCCCCCCCC
IDQNLPAVMTDIGYVRSKWVMEKVADLAASRGLPLMTFRLGYATFHRDTGLSANYQWWGR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHEECCCCCCCCHHHHHH
LVRTCIDQQQIPDLRNLREGLTTVDYMTHAIAHISRNPSALGHKYNLVHTDDNNLTLRQF
HHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEEECCCCCHHHHH
FERLERHFGLRFETVPFRQWLDGWQHDTAAPLYPLLSLFRDVMYDGRSTVELYQDTYRWR
HHHHHHHHCCEEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
CDRVQAALQGSGIEEPTFTRDELARYLTQSIGHRV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA