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The map label for this gene is uxuR [H]

Identifier: 189353669

GI number: 189353669

Start: 1931903

End: 1932664

Strand: Reverse

Name: uxuR [H]

Synonym: BMULJ_04914

Alternate gene names: 189353669

Gene position: 1932664-1931903 (Counterclockwise)

Preceding gene: 189353670

Following gene: 189353660

Centisome position: 78.15

GC content: 68.77

Gene sequence:

>762_bases
ATGTCCATCCAGCCGATTCAAAACCGCCGCCTTTACCAGCAGATCGCCGACCGGCTCACCGCGATGATCGAGTCCGGCGA
TTTTCCGCCGGGCAGCTATCTGCCGCCGGAGCGCGAGCTGGCCGAGCAGTTCGGCGTGTCGCGCACGTCGGTGCGCGAGG
CGCTGATCGCGCTCGAAGTGGGCGGGCGCGTCAGCGTGCGCGTCGGCGACGGCGTGAAGGTGCGCCATCCGGAGGCCGCG
ACGGCACCGGCGCCTGCCGCCGCCGCGAAGGCCGCGCCGCTTGCGGTCGTCGAGATCGATCCCGAGCTGGGGATCGCGCT
CGATCTCGATACCGAAATCCCGCCGTTCGCGCTGCTGCAGGCACGGCGCCTGATCGAGCCCGAAGCCGCGTCGCTCGCCG
CGAAGCATGCCTCGGACGCGCAGATCGAGGCGATCGGCGCCGCGTTCGAGCGCAATCAGGCGGACAATCGCAGCGGCTCG
GTCACGCATCCGGGCGACCGGCTGTTCCATATCCGCATCGCGGAGGCGAGCGACAACGCGGCCTATGCGCTGATGGTCAA
GCAACTGCTCGCGCATAAATACGATCCGATGTTTCAGCGATTGCAGTCGCTGTACATGCCGCACGACATGCCGCATCGGT
CGGAACTCGAACATCGCGCGATCCTCGACGCGATCCGCGCGCGCGACCCCGAGGCCGCGCGCCGCGCGATGGCGGAGCAT
CTCGACGAGGTGATCCGGATCTTCGGGCGCGCGCTCGACTGA

Upstream 100 bases:

>100_bases
CGCTGCCGGAACCGGCCGACGCGCGCCTATAAAATACGCGCGCACGATCCGCCCGCTTCGCCGGCCCGTTCGCCACGCAA
CCGATTTTCCGCATCGACGT

Downstream 100 bases:

>100_bases
CGCGCGGCGCGGTGCGCGTGCGCGCGCCGCGTCAGAAGCGATCGGCGCGATACGGCGCCGGATCGGTGAACGGCGTGTCG
CCCGTCATCATTTCGGCGAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSIQPIQNRRLYQQIADRLTAMIESGDFPPGSYLPPERELAEQFGVSRTSVREALIALEVGGRVSVRVGDGVKVRHPEAA
TAPAPAAAAKAAPLAVVEIDPELGIALDLDTEIPPFALLQARRLIEPEAASLAAKHASDAQIEAIGAAFERNQADNRSGS
VTHPGDRLFHIRIAEASDNAAYALMVKQLLAHKYDPMFQRLQSLYMPHDMPHRSELEHRAILDAIRARDPEAARRAMAEH
LDEVIRIFGRALD

Sequences:

>Translated_253_residues
MSIQPIQNRRLYQQIADRLTAMIESGDFPPGSYLPPERELAEQFGVSRTSVREALIALEVGGRVSVRVGDGVKVRHPEAA
TAPAPAAAAKAAPLAVVEIDPELGIALDLDTEIPPFALLQARRLIEPEAASLAAKHASDAQIEAIGAAFERNQADNRSGS
VTHPGDRLFHIRIAEASDNAAYALMVKQLLAHKYDPMFQRLQSLYMPHDMPHRSELEHRAILDAIRARDPEAARRAMAEH
LDEVIRIFGRALD
>Mature_252_residues
SIQPIQNRRLYQQIADRLTAMIESGDFPPGSYLPPERELAEQFGVSRTSVREALIALEVGGRVSVRVGDGVKVRHPEAAT
APAPAAAAKAAPLAVVEIDPELGIALDLDTEIPPFALLQARRLIEPEAASLAAKHASDAQIEAIGAAFERNQADNRSGSV
THPGDRLFHIRIAEASDNAAYALMVKQLLAHKYDPMFQRLQSLYMPHDMPHRSELEHRAILDAIRARDPEAARRAMAEHL
DEVIRIFGRALD

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=252, Percent_Identity=34.5238095238095, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790780, Length=243, Percent_Identity=34.156378600823, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790032, Length=237, Percent_Identity=31.2236286919831, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789621, Length=249, Percent_Identity=32.5301204819277, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789353, Length=243, Percent_Identity=24.6913580246914, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786303, Length=253, Percent_Identity=28.4584980237154, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27751; Mature: 27620

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQPIQNRRLYQQIADRLTAMIESGDFPPGSYLPPERELAEQFGVSRTSVREALIALEV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHEEC
GGRVSVRVGDGVKVRHPEAATAPAPAAAAKAAPLAVVEIDPELGIALDLDTEIPPFALLQ
CCEEEEEECCCEEEECCCCCCCCCCHHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHHH
ARRLIEPEAASLAAKHASDAQIEAIGAAFERNQADNRSGSVTHPGDRLFHIRIAEASDNA
HHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCH
AYALMVKQLLAHKYDPMFQRLQSLYMPHDMPHRSELEHRAILDAIRARDPEAARRAMAEH
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LDEVIRIFGRALD
HHHHHHHHHHHCC
>Mature Secondary Structure 
SIQPIQNRRLYQQIADRLTAMIESGDFPPGSYLPPERELAEQFGVSRTSVREALIALEV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHEEC
GGRVSVRVGDGVKVRHPEAATAPAPAAAAKAAPLAVVEIDPELGIALDLDTEIPPFALLQ
CCEEEEEECCCEEEECCCCCCCCCCHHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHHH
ARRLIEPEAASLAAKHASDAQIEAIGAAFERNQADNRSGSVTHPGDRLFHIRIAEASDNA
HHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCH
AYALMVKQLLAHKYDPMFQRLQSLYMPHDMPHRSELEHRAILDAIRARDPEAARRAMAEH
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LDEVIRIFGRALD
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]