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The map label for this gene is yjiA [H]

Identifier: 189353665

GI number: 189353665

Start: 1926078

End: 1927205

Strand: Direct

Name: yjiA [H]

Synonym: BMULJ_04910

Alternate gene names: 189353665

Gene position: 1926078-1927205 (Clockwise)

Preceding gene: 189353664

Following gene: 189353666

Centisome position: 77.88

GC content: 66.13

Gene sequence:

>1128_bases
ATGACGCATATCCACACCACGCACAGCGACGTCGAGAAGATCCCGGTCACCGTGCTCACCGGCTTTCTCGGCGCGGGCAA
GACCACGCTGCTCAACTACATCCTGCGCGAAAAGCACGGCCGCAAGATCGCGGTGATCGAGAACGAGTTCGGCGAGATCG
GCATCGACGGCGGCCTCGTGCTGGAATCGACCGAGGAAATCTACGAGATGACGAACGGCTGCGTGTGCTGCGTCGGCGCC
GTGCGCGAGGATCTGGTACGCATCGTGCGGATGCTCGTCGCGCGGCCCGACCGGCTCGATCACATCATCGTCGAGACGAG
CGGCCTCGCCGATCCGTATCCGGTCGCGCAGACGTTCTTTCTCGACGATCCGATCGCGAAGGAGGTCGCGCTCGATGCAG
TCGTCACGATGGTCGATGCGAAACACATTCGCGCGCATCTCGACGATCTCGTGCTCGACGGCCGCGACAACCAGGCGGTC
GATCAGATCGTCTGCGCGGACCGCATCGTGATCAACAAGGTCGATCTCGTCGACGCAGCGGACGTCGAATCGCTGAGCGC
GCGGCTGCGCGAACTGAACGCGACGGCCGAAATCGTCACGTCGAGCTACGCGCAGGTCGATCTCGATCGCATTCTCGGCG
TCGGCGCGAACGAATTCGCACAGATTCTCGTCGAGAGCGACGGGCTGCACGCGGACACGGACGCGCATGTCGACAACCAT
GCGGACGAACACGCGACGCACGACGCGCACGGCGGCCACGATACGCACGCGCACGGCGATCACCCCAGCCACGACGATCA
CGACGACCACGAACACGACGCGAGCGTGTCGTCGGTCGGGATCGAAGTCGACGCCGACGTCGATCTCGACGCGCTCGAAG
CGTGGCTCGCGGAGCTGCGCGACGCCGACACGGCGAACCTGTTCCGGATGAAAGGGATTCTCGCGGTGCACGGCCGCGCG
CAGCGCTACGTGCTGCAGGGCGTGCACGGCGTGATCGAGCTGCGCGCCGCGCAGGCGTGGGGCACGGAGCCGCGTGCGTC
GCGCATCGTCTTCATCGGCCGCGATCTCGATCGCGCCGCGCTGACCGACCGTTTCCATGCCTGTCTCGCCGCGCCGGTCG
CGGCCTGA

Upstream 100 bases:

>100_bases
CGCTCGGCCGCGTGCTCGATCTGTTCGACATCGATTCCCGCACCGTCCATCGCTGGAAGGACAACGATTCGCTGCCCCAC
CGACTCAACGGAGACGCATC

Downstream 100 bases:

>100_bases
CGAGGCGCCAGGCGCGCGCATGCCGCGCGCGCCGGATCACGAACATCAGGAGACACGCCCATGCACTCTGCCTCACATCC
CGTCGACCGCATACTGCCGC

Product: cobalamin biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTHIHTTHSDVEKIPVTVLTGFLGAGKTTLLNYILREKHGRKIAVIENEFGEIGIDGGLVLESTEEIYEMTNGCVCCVGA
VREDLVRIVRMLVARPDRLDHIIVETSGLADPYPVAQTFFLDDPIAKEVALDAVVTMVDAKHIRAHLDDLVLDGRDNQAV
DQIVCADRIVINKVDLVDAADVESLSARLRELNATAEIVTSSYAQVDLDRILGVGANEFAQILVESDGLHADTDAHVDNH
ADEHATHDAHGGHDTHAHGDHPSHDDHDDHEHDASVSSVGIEVDADVDLDALEAWLAELRDADTANLFRMKGILAVHGRA
QRYVLQGVHGVIELRAAQAWGTEPRASRIVFIGRDLDRAALTDRFHACLAAPVAA

Sequences:

>Translated_375_residues
MTHIHTTHSDVEKIPVTVLTGFLGAGKTTLLNYILREKHGRKIAVIENEFGEIGIDGGLVLESTEEIYEMTNGCVCCVGA
VREDLVRIVRMLVARPDRLDHIIVETSGLADPYPVAQTFFLDDPIAKEVALDAVVTMVDAKHIRAHLDDLVLDGRDNQAV
DQIVCADRIVINKVDLVDAADVESLSARLRELNATAEIVTSSYAQVDLDRILGVGANEFAQILVESDGLHADTDAHVDNH
ADEHATHDAHGGHDTHAHGDHPSHDDHDDHEHDASVSSVGIEVDADVDLDALEAWLAELRDADTANLFRMKGILAVHGRA
QRYVLQGVHGVIELRAAQAWGTEPRASRIVFIGRDLDRAALTDRFHACLAAPVAA
>Mature_374_residues
THIHTTHSDVEKIPVTVLTGFLGAGKTTLLNYILREKHGRKIAVIENEFGEIGIDGGLVLESTEEIYEMTNGCVCCVGAV
REDLVRIVRMLVARPDRLDHIIVETSGLADPYPVAQTFFLDDPIAKEVALDAVVTMVDAKHIRAHLDDLVLDGRDNQAVD
QIVCADRIVINKVDLVDAADVESLSARLRELNATAEIVTSSYAQVDLDRILGVGANEFAQILVESDGLHADTDAHVDNHA
DEHATHDAHGGHDTHAHGDHPSHDDHDDHEHDASVSSVGIEVDADVDLDALEAWLAELRDADTANLFRMKGILAVHGRAQ
RYVLQGVHGVIELRAAQAWGTEPRASRIVFIGRDLDRAALTDRFHACLAAPVAA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=390, Percent_Identity=32.8205128205128, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI126722884, Length=393, Percent_Identity=32.5699745547074, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI148727351, Length=393, Percent_Identity=32.5699745547074, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI146231952, Length=389, Percent_Identity=32.3907455012853, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI223941779, Length=390, Percent_Identity=31.5384615384615, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI223941776, Length=362, Percent_Identity=31.2154696132597, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI119120938, Length=175, Percent_Identity=40.5714285714286, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI310124599, Length=228, Percent_Identity=25.8771929824561, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI87082430, Length=348, Percent_Identity=31.3218390804598, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788499, Length=197, Percent_Identity=30.4568527918782, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=230, Percent_Identity=33.9130434782609, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 40805; Mature: 40674

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIHTTHSDVEKIPVTVLTGFLGAGKTTLLNYILREKHGRKIAVIENEFGEIGIDGGLV
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEE
LESTEEIYEMTNGCVCCVGAVREDLVRIVRMLVARPDRLDHIIVETSGLADPYPVAQTFF
ECCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHEEE
LDDPIAKEVALDAVVTMVDAKHIRAHLDDLVLDGRDNQAVDQIVCADRIVINKVDLVDAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCHHEEEEECCCCCC
DVESLSARLRELNATAEIVTSSYAQVDLDRILGVGANEFAQILVESDGLHADTDAHVDNH
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCC
ADEHATHDAHGGHDTHAHGDHPSHDDHDDHEHDASVSSVGIEVDADVDLDALEAWLAELR
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCEEEECCCCHHHHHHHHHHHH
DADTANLFRMKGILAVHGRAQRYVLQGVHGVIELRAAQAWGTEPRASRIVFIGRDLDRAA
CCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
LTDRFHACLAAPVAA
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
THIHTTHSDVEKIPVTVLTGFLGAGKTTLLNYILREKHGRKIAVIENEFGEIGIDGGLV
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEE
LESTEEIYEMTNGCVCCVGAVREDLVRIVRMLVARPDRLDHIIVETSGLADPYPVAQTFF
ECCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHEEE
LDDPIAKEVALDAVVTMVDAKHIRAHLDDLVLDGRDNQAVDQIVCADRIVINKVDLVDAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCHHEEEEECCCCCC
DVESLSARLRELNATAEIVTSSYAQVDLDRILGVGANEFAQILVESDGLHADTDAHVDNH
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCC
ADEHATHDAHGGHDTHAHGDHPSHDDHDDHEHDASVSSVGIEVDADVDLDALEAWLAELR
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCEEEECCCCHHHHHHHHHHHH
DADTANLFRMKGILAVHGRAQRYVLQGVHGVIELRAAQAWGTEPRASRIVFIGRDLDRAA
CCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
LTDRFHACLAAPVAA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]