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The map label for this gene is rcsC [H]

Identifier: 189353557

GI number: 189353557

Start: 1795888

End: 1797672

Strand: Direct

Name: rcsC [H]

Synonym: BMULJ_04801

Alternate gene names: 189353557

Gene position: 1795888-1797672 (Clockwise)

Preceding gene: 189353552

Following gene: 189353558

Centisome position: 72.62

GC content: 71.04

Gene sequence:

>1785_bases
ATGCGCCCGCACCGCCTCTTTTCCATCGACTCGACCGACATCGCGCACGATGCCGCCACGGCGAGCATCGCCGCCACCAC
CTTGCTGGCCGTCGCGCTCGCGAGCGCGCTGCATCGGCTCGGCAGTCTCGACGCGACCGTCGGGACCGTGTGGGTGTCGT
ACGTCGCGGGCAGCTCGGCCGGCCTCGCGATCGTCGCGCACCGCGATCGCCGCTCGGCCATGCGCGCCGGCAATCGCACC
GTTTCGAGCGCGTGGCGCGTCGCGTTCGGCGCCGCGGCCGGCATCGGCTGGGGATCGGCCGGCCTTCACGCGACCGCCGT
CGCCGACGCACACACGCAGATCGCCGTCGCGATGGCGACGCTCGCGGTCGTCGCGGCCGCCGCACCGCACTTCAGCCCGT
CGACTCCTGCGCTGCTCGCCTTCGTGCTGCCGGCGACCGCACCGGGCGTCGTCGCCGCCGCGCTGTCGCCACACGCCGCA
CCGCGTGCGATTGCACCGACGTTGTTCGGCATCGCCGCGCTCGCCGGCATCGTTGCGCTGCTCGCGCACCGTACGTTCAT
ACGCCATGCCAGGCTGCAATCGGACGCCGAACGGCGCGCCGACGCGCTGCAGCGCGATCGCGACGCCGCCGTGCAGCGCG
CGGTCGATCTGCGTCGACAGAAGCTGCGCGCGGAAGCCGCGAATCTCGCGAAATCGCGGCTGCTCGCCGCCGCGAGCCAC
GATCTTCGCCAGCCGTCGCACGCGCTCGGCGTGCTGGTCGGCGCGCTTCGCGGCGTACCGATGCCAGATGACGGTCAACG
GCTGCTGCAGCAGATCGAGCTCTCGACGCGCGCGCTCGACACGCTCTTCGGTGCCTTGCTCGACGTGTCGCGGCTCGATG
CCGGCATCGTCGAGGTGCATCGGCGGCCGTTCGCGATCGACACCGTGCTCGCTCGCGTTTGCAACGAATATCTGCTCGAT
GCGTCCGCGAAAGGCCTGCGTCTGTCGCGCGTGCCGTGCCGCGCGATCGTCGATTCCGATCCGGTGCTGATCGAGCGCGT
CGTGCGCAATCTCGTCAGCAATGCGGTGCGCTATACCGACGCGGGCCGCATCGTCGTCGGCTGCCGCTACCGCGGTGCAC
ACATCGCGATCGAAATCCGCGATACGGGCCGCGGCATCGCGCGCGATCAGCTCGAACTCGTCTTTCGCGAGTATTACCGC
GTCGACGGCGCCGCGTCGGACCACGACGGCGGATTCGGGCTTGGGCTCGCGATCGTGCGCCGGCTCGTCGCGCTGCTCGG
ATGCCGGTTGTCGGTGCGGTCGGAACCGGGACGCGGGTCGTGTTTCGTCGTCTCGGTGCCGCGCGCGCGGCCCGCGGGCG
GAGTGCGCCGGCACGCGGCGCGGGCCGCCGCGTTCGTGGTCGTCGTCGACGACACACGCGCCGTACGCGACGCGATCGCA
CGCCGGCTCGCACGATGGGGTTACGACACGCTGTCGGCACGCTCCGCCGACGAAGCGATCGACCGGCTGTCGAGGTGCAC
GACACGCCCGAGCGTGTTCGTCAGCGCATTGCGTCTGCACGGTACGGAGACCGGCATCGACGTGATCGACCGTCTGCGCG
CCGAATACAATCTCGCGATTCCGGCGCTGCTGATCGGCGACGCATCCGATACGGCGCCGCTCGCCGATGCAAACGGCTGC
CTGCTGCTGCACCGCCCGATCGAGAACGGGCAGCTGCGCGCGGCGATCGCGCGACTCGTCGCGACAGGTGCGCCTGCCGG
AGCGGTTGAAGCGATCGACGACTGA

Upstream 100 bases:

>100_bases
CGAATCGGCTCGGCGGCGACTATTCTGTCTAAAGGATCGACTGTCCGCGCACATCGTTCGCCACCCGCCTCGCCCGCGCG
CGACGAACGTGCGCAGCCCC

Downstream 100 bases:

>100_bases
CGCACGGGCGCGCACATGTGCCGCAACGCGCACGTTTATTTCATCGAGAAATATCTCGACGCCGACGCGGCCATCGCACG
CGCCCGCTTCCCGCAAACGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MRPHRLFSIDSTDIAHDAATASIAATTLLAVALASALHRLGSLDATVGTVWVSYVAGSSAGLAIVAHRDRRSAMRAGNRT
VSSAWRVAFGAAAGIGWGSAGLHATAVADAHTQIAVAMATLAVVAAAAPHFSPSTPALLAFVLPATAPGVVAAALSPHAA
PRAIAPTLFGIAALAGIVALLAHRTFIRHARLQSDAERRADALQRDRDAAVQRAVDLRRQKLRAEAANLAKSRLLAAASH
DLRQPSHALGVLVGALRGVPMPDDGQRLLQQIELSTRALDTLFGALLDVSRLDAGIVEVHRRPFAIDTVLARVCNEYLLD
ASAKGLRLSRVPCRAIVDSDPVLIERVVRNLVSNAVRYTDAGRIVVGCRYRGAHIAIEIRDTGRGIARDQLELVFREYYR
VDGAASDHDGGFGLGLAIVRRLVALLGCRLSVRSEPGRGSCFVVSVPRARPAGGVRRHAARAAAFVVVVDDTRAVRDAIA
RRLARWGYDTLSARSADEAIDRLSRCTTRPSVFVSALRLHGTETGIDVIDRLRAEYNLAIPALLIGDASDTAPLADANGC
LLLHRPIENGQLRAAIARLVATGAPAGAVEAIDD

Sequences:

>Translated_594_residues
MRPHRLFSIDSTDIAHDAATASIAATTLLAVALASALHRLGSLDATVGTVWVSYVAGSSAGLAIVAHRDRRSAMRAGNRT
VSSAWRVAFGAAAGIGWGSAGLHATAVADAHTQIAVAMATLAVVAAAAPHFSPSTPALLAFVLPATAPGVVAAALSPHAA
PRAIAPTLFGIAALAGIVALLAHRTFIRHARLQSDAERRADALQRDRDAAVQRAVDLRRQKLRAEAANLAKSRLLAAASH
DLRQPSHALGVLVGALRGVPMPDDGQRLLQQIELSTRALDTLFGALLDVSRLDAGIVEVHRRPFAIDTVLARVCNEYLLD
ASAKGLRLSRVPCRAIVDSDPVLIERVVRNLVSNAVRYTDAGRIVVGCRYRGAHIAIEIRDTGRGIARDQLELVFREYYR
VDGAASDHDGGFGLGLAIVRRLVALLGCRLSVRSEPGRGSCFVVSVPRARPAGGVRRHAARAAAFVVVVDDTRAVRDAIA
RRLARWGYDTLSARSADEAIDRLSRCTTRPSVFVSALRLHGTETGIDVIDRLRAEYNLAIPALLIGDASDTAPLADANGC
LLLHRPIENGQLRAAIARLVATGAPAGAVEAIDD
>Mature_594_residues
MRPHRLFSIDSTDIAHDAATASIAATTLLAVALASALHRLGSLDATVGTVWVSYVAGSSAGLAIVAHRDRRSAMRAGNRT
VSSAWRVAFGAAAGIGWGSAGLHATAVADAHTQIAVAMATLAVVAAAAPHFSPSTPALLAFVLPATAPGVVAAALSPHAA
PRAIAPTLFGIAALAGIVALLAHRTFIRHARLQSDAERRADALQRDRDAAVQRAVDLRRQKLRAEAANLAKSRLLAAASH
DLRQPSHALGVLVGALRGVPMPDDGQRLLQQIELSTRALDTLFGALLDVSRLDAGIVEVHRRPFAIDTVLARVCNEYLLD
ASAKGLRLSRVPCRAIVDSDPVLIERVVRNLVSNAVRYTDAGRIVVGCRYRGAHIAIEIRDTGRGIARDQLELVFREYYR
VDGAASDHDGGFGLGLAIVRRLVALLGCRLSVRSEPGRGSCFVVSVPRARPAGGVRRHAARAAAFVVVVDDTRAVRDAIA
RRLARWGYDTLSARSADEAIDRLSRCTTRPSVFVSALRLHGTETGIDVIDRLRAEYNLAIPALLIGDASDTAPLADANGC
LLLHRPIENGQLRAAIARLVATGAPAGAVEAIDD

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=30.6818181818182, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=30.8695652173913, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=32.7067669172932, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=34.6613545816733, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788713, Length=343, Percent_Identity=25.6559766763848, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=29.5833333333333, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=29.2035398230088, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=30.2631578947368, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=128, Percent_Identity=35.15625, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790436, Length=298, Percent_Identity=24.496644295302, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=25.6756756756757, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62706; Mature: 62706

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00527 RIBOSOMAL_S14 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPHRLFSIDSTDIAHDAATASIAATTLLAVALASALHRLGSLDATVGTVWVSYVAGSSA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GLAIVAHRDRRSAMRAGNRTVSSAWRVAFGAAAGIGWGSAGLHATAVADAHTQIAVAMAT
CEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
LAVVAAAAPHFSPSTPALLAFVLPATAPGVVAAALSPHAAPRAIAPTLFGIAALAGIVAL
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LAHRTFIRHARLQSDAERRADALQRDRDAAVQRAVDLRRQKLRAEAANLAKSRLLAAASH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRQPSHALGVLVGALRGVPMPDDGQRLLQQIELSTRALDTLFGALLDVSRLDAGIVEVH
HHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRPFAIDTVLARVCNEYLLDASAKGLRLSRVPCRAIVDSDPVLIERVVRNLVSNAVRYTD
CCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCC
AGRIVVGCRYRGAHIAIEIRDTGRGIARDQLELVFREYYRVDGAASDHDGGFGLGLAIVR
CCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
RLVALLGCRLSVRSEPGRGSCFVVSVPRARPAGGVRRHAARAAAFVVVVDDTRAVRDAIA
HHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHEEEEEEECCHHHHHHHHH
RRLARWGYDTLSARSADEAIDRLSRCTTRPSVFVSALRLHGTETGIDVIDRLRAEYNLAI
HHHHHCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
PALLIGDASDTAPLADANGCLLLHRPIENGQLRAAIARLVATGAPAGAVEAIDD
CEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRPHRLFSIDSTDIAHDAATASIAATTLLAVALASALHRLGSLDATVGTVWVSYVAGSSA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GLAIVAHRDRRSAMRAGNRTVSSAWRVAFGAAAGIGWGSAGLHATAVADAHTQIAVAMAT
CEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
LAVVAAAAPHFSPSTPALLAFVLPATAPGVVAAALSPHAAPRAIAPTLFGIAALAGIVAL
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LAHRTFIRHARLQSDAERRADALQRDRDAAVQRAVDLRRQKLRAEAANLAKSRLLAAASH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRQPSHALGVLVGALRGVPMPDDGQRLLQQIELSTRALDTLFGALLDVSRLDAGIVEVH
HHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRPFAIDTVLARVCNEYLLDASAKGLRLSRVPCRAIVDSDPVLIERVVRNLVSNAVRYTD
CCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCC
AGRIVVGCRYRGAHIAIEIRDTGRGIARDQLELVFREYYRVDGAASDHDGGFGLGLAIVR
CCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
RLVALLGCRLSVRSEPGRGSCFVVSVPRARPAGGVRRHAARAAAFVVVVDDTRAVRDAIA
HHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHEEEEEEECCHHHHHHHHH
RRLARWGYDTLSARSADEAIDRLSRCTTRPSVFVSALRLHGTETGIDVIDRLRAEYNLAI
HHHHHCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
PALLIGDASDTAPLADANGCLLLHRPIENGQLRAAIARLVATGAPAGAVEAIDD
CEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]