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The map label for this gene is norG [H]

Identifier: 189353551

GI number: 189353551

Start: 1788885

End: 1790372

Strand: Direct

Name: norG [H]

Synonym: BMULJ_04795

Alternate gene names: 189353551

Gene position: 1788885-1790372 (Clockwise)

Preceding gene: 189353549

Following gene: 189353552

Centisome position: 72.33

GC content: 71.51

Gene sequence:

>1488_bases
ATGACCCGTTCCGTCCCGAACCCGGCCGCACCCGCCGCGTCGCGCACGCGCGTCGAAACCGTGATGGACACGCTGCGCGC
GCGCATCTCGAGCCGCACGTTGATGCCGGGCGCGCGCGTGCCGTCGATCCGCATGATGGCCGACTCGCTGCGCGTGTCGA
AGTCGACCGTCGTCGACGCATACGAGCGGCTCGCCAGCGAAGGCGTGCTCGTCGCACGCCGCGGCTCGGGCTTCTACGTG
TCGGGGCACGCGCCGCCGCTCGCGCTGGCGGATCTCGGCCCGCGGCTCGATCGCGAACTCGATCCCTTATGGCTCACGCG
TCAGTCGCTCGAATCGGCGCCGAGCGCGATGAAGCCCGGCTGCGGGTGGCTGCCGTCGTCGTGGCTGCCCGACGAAAGCC
TGCGCCGTGCGCTGCGCGCCGCGTCGCGCGACGAGTCCGACGCACTGACCGATTACGCGACGCCCGCCGGCCTGCCCGCG
CTGCGTCAGCAGCTCGCGTGGCGTCTCGCGCAGCACGGCGTCCATGCGGAACCCGCGCAGATCATGCTCGCCGACAGCGG
CACGCAGGCGCTCGATTTCGTCTGCCGGCTGCTACTCGAACCGGGCGACACGGTCGTGCTCGACGATCCCTGCTATTTCA
ATTTCCAGGCGCTGCTGCGCGCGCATCGCGCGCGGATCGTCAGCGTGCCCTACACGCCGAACGGCCCCGATCTCGCGCGC
TTCGAGCAGACGCTCGTCGAGCACCGGCCGCGCCTCTACATCACCAACGCGGCGCTGCACAATCCGACCGGCGCGACGCT
GTCGCCGCCCGTCGCGCACCGGCTGCTGACGCTCGCGGCCGACCATGGACTGCTGATCGTCGAGGACGACATCTTCGCGG
ATTTCGAAAGCACGCCCGCGCCGCGGCTCGCCGCATTCGACGGGCTGCAGCGCGTCGTGTCGATCGGCAGCTTCTCGAAG
ACGCTGTCGGCCGCGATCCGCTGCGGCTATGTCGCCGCGCGGCCGGAGTGGATCGACGCGCTCGTCGACCTCAAGCTCGC
GACGTCGTTTGGCCATGCGCAGATCGGCGCGAACGTCGTGCACCGGCTGCTCGTCGACGGCACCTATCGGCGCCATCTGG
ACGCCCTGCGTGCACGTCTCGCGGACGCGATGGGCGAAACGATCCGCCGGCTCGCACGCGCGGGGCTCGCGGTCTGGACC
GAGCCGCGCGGCGGCCTGTTCGTGTGGGCGCAGCTGCCGGACGCGCTCGATGCGGCGCGCGTCGCGCGGCATGCGCTCGA
CGACGATGTCGTGCTCGCGCCCGGCAACGTGTTCAGCGTGTCGCATGGCGCGACGTCGTATCTGCGCTTCAACGTGTCGC
GCTGCAAGGAGCCGGCGGTGTTCGACGCGCTCGCGCGCGCGATGGATGCGGCGCGCGTGTCGACGGCCGGAGTACGTACG
GCCGAGCGGCGCGGCACGCTGGCGTGCGATCGGCACGATACCGCGTAG

Upstream 100 bases:

>100_bases
TGACCGATGATCCGCCGCCCGTGAAATGCGCGTAAGCTACACCGCAATACAATTCCGACAAACTGTACTGGACAACCGGC
CGTACAGTTCAACGCCGACC

Downstream 100 bases:

>100_bases
TCGCGCAATCGACGGCGCGCGCGGCTGTATCGATGGAACCCGCGCTCGACTTGACGAAATCTGAAGAACGGCGCGATTTT
GGCGCGCTACACTCGGCTTC

Product: transcriptional MocR family regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTRSVPNPAAPAASRTRVETVMDTLRARISSRTLMPGARVPSIRMMADSLRVSKSTVVDAYERLASEGVLVARRGSGFYV
SGHAPPLALADLGPRLDRELDPLWLTRQSLESAPSAMKPGCGWLPSSWLPDESLRRALRAASRDESDALTDYATPAGLPA
LRQQLAWRLAQHGVHAEPAQIMLADSGTQALDFVCRLLLEPGDTVVLDDPCYFNFQALLRAHRARIVSVPYTPNGPDLAR
FEQTLVEHRPRLYITNAALHNPTGATLSPPVAHRLLTLAADHGLLIVEDDIFADFESTPAPRLAAFDGLQRVVSIGSFSK
TLSAAIRCGYVAARPEWIDALVDLKLATSFGHAQIGANVVHRLLVDGTYRRHLDALRARLADAMGETIRRLARAGLAVWT
EPRGGLFVWAQLPDALDAARVARHALDDDVVLAPGNVFSVSHGATSYLRFNVSRCKEPAVFDALARAMDAARVSTAGVRT
AERRGTLACDRHDTA

Sequences:

>Translated_495_residues
MTRSVPNPAAPAASRTRVETVMDTLRARISSRTLMPGARVPSIRMMADSLRVSKSTVVDAYERLASEGVLVARRGSGFYV
SGHAPPLALADLGPRLDRELDPLWLTRQSLESAPSAMKPGCGWLPSSWLPDESLRRALRAASRDESDALTDYATPAGLPA
LRQQLAWRLAQHGVHAEPAQIMLADSGTQALDFVCRLLLEPGDTVVLDDPCYFNFQALLRAHRARIVSVPYTPNGPDLAR
FEQTLVEHRPRLYITNAALHNPTGATLSPPVAHRLLTLAADHGLLIVEDDIFADFESTPAPRLAAFDGLQRVVSIGSFSK
TLSAAIRCGYVAARPEWIDALVDLKLATSFGHAQIGANVVHRLLVDGTYRRHLDALRARLADAMGETIRRLARAGLAVWT
EPRGGLFVWAQLPDALDAARVARHALDDDVVLAPGNVFSVSHGATSYLRFNVSRCKEPAVFDALARAMDAARVSTAGVRT
AERRGTLACDRHDTA
>Mature_494_residues
TRSVPNPAAPAASRTRVETVMDTLRARISSRTLMPGARVPSIRMMADSLRVSKSTVVDAYERLASEGVLVARRGSGFYVS
GHAPPLALADLGPRLDRELDPLWLTRQSLESAPSAMKPGCGWLPSSWLPDESLRRALRAASRDESDALTDYATPAGLPAL
RQQLAWRLAQHGVHAEPAQIMLADSGTQALDFVCRLLLEPGDTVVLDDPCYFNFQALLRAHRARIVSVPYTPNGPDLARF
EQTLVEHRPRLYITNAALHNPTGATLSPPVAHRLLTLAADHGLLIVEDDIFADFESTPAPRLAAFDGLQRVVSIGSFSKT
LSAAIRCGYVAARPEWIDALVDLKLATSFGHAQIGANVVHRLLVDGTYRRHLDALRARLADAMGETIRRLARAGLAVWTE
PRGGLFVWAQLPDALDAARVARHALDDDVVLAPGNVFSVSHGATSYLRFNVSRCKEPAVFDALARAMDAARVSTAGVRTA
ERRGTLACDRHDTA

Specific function: Positively regulates the expression of the NorB efflux pump and negatively regulates the expression of the AbcA efflux pump. Binds specifically to the promoters of norA, norB and norC and abcA genes. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=360, Percent_Identity=26.1111111111111, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI33469970, Length=360, Percent_Identity=26.1111111111111, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI1787710, Length=449, Percent_Identity=28.0623608017817, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790797, Length=454, Percent_Identity=25.3303964757709, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356535, Length=360, Percent_Identity=21.3888888888889, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53734; Mature: 53603

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50949 HTH_GNTR ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSVPNPAAPAASRTRVETVMDTLRARISSRTLMPGARVPSIRMMADSLRVSKSTVVDA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YERLASEGVLVARRGSGFYVSGHAPPLALADLGPRLDRELDPLWLTRQSLESAPSAMKPG
HHHHHCCCEEEEECCCCEEEECCCCCCHHHHCCCHHCCCCCHHHHHHHHHHCCCCCCCCC
CGWLPSSWLPDESLRRALRAASRDESDALTDYATPAGLPALRQQLAWRLAQHGVHAEPAQ
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
IMLADSGTQALDFVCRLLLEPGDTVVLDDPCYFNFQALLRAHRARIVSVPYTPNGPDLAR
EEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCEEEECCCCCCCCCHHH
FEQTLVEHRPRLYITNAALHNPTGATLSPPVAHRLLTLAADHGLLIVEDDIFADFESTPA
HHHHHHHCCCCEEEEECCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHCCCCCCCC
PRLAAFDGLQRVVSIGSFSKTLSAAIRCGYVAARPEWIDALVDLKLATSFGHAQIGANVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHH
HRLLVDGTYRRHLDALRARLADAMGETIRRLARAGLAVWTEPRGGLFVWAQLPDALDAAR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHHHH
VARHALDDDVVLAPGNVFSVSHGATSYLRFNVSRCKEPAVFDALARAMDAARVSTAGVRT
HHHHHCCCCEEECCCCEEEECCCCCHHEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCHH
AERRGTLACDRHDTA
HHHCCCEECCCCCCC
>Mature Secondary Structure 
TRSVPNPAAPAASRTRVETVMDTLRARISSRTLMPGARVPSIRMMADSLRVSKSTVVDA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YERLASEGVLVARRGSGFYVSGHAPPLALADLGPRLDRELDPLWLTRQSLESAPSAMKPG
HHHHHCCCEEEEECCCCEEEECCCCCCHHHHCCCHHCCCCCHHHHHHHHHHCCCCCCCCC
CGWLPSSWLPDESLRRALRAASRDESDALTDYATPAGLPALRQQLAWRLAQHGVHAEPAQ
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
IMLADSGTQALDFVCRLLLEPGDTVVLDDPCYFNFQALLRAHRARIVSVPYTPNGPDLAR
EEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCEEEECCCCCCCCCHHH
FEQTLVEHRPRLYITNAALHNPTGATLSPPVAHRLLTLAADHGLLIVEDDIFADFESTPA
HHHHHHHCCCCEEEEECCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHCCCCCCCC
PRLAAFDGLQRVVSIGSFSKTLSAAIRCGYVAARPEWIDALVDLKLATSFGHAQIGANVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHH
HRLLVDGTYRRHLDALRARLADAMGETIRRLARAGLAVWTEPRGGLFVWAQLPDALDAAR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHHHH
VARHALDDDVVLAPGNVFSVSHGATSYLRFNVSRCKEPAVFDALARAMDAARVSTAGVRT
HHHHHCCCCEEECCCCEEEECCCCCHHEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCHH
AERRGTLACDRHDTA
HHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA