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The map label for this gene is tcp [H]

Identifier: 189353494

GI number: 189353494

Start: 1712981

End: 1714534

Strand: Direct

Name: tcp [H]

Synonym: BMULJ_04738

Alternate gene names: 189353494

Gene position: 1712981-1714534 (Clockwise)

Preceding gene: 189353485

Following gene: 189353496

Centisome position: 69.26

GC content: 66.67

Gene sequence:

>1554_bases
ATGCGCACTCTCACCCTCAATCAGAAACTGGCTTCGATGATCGTCATCCTGTGGCTCGGCCTGCTCGTCATCGCCGGGCT
CGGTGCATGGCAGACGCGCGCCTCGATGATCGACGACCGTCGCGAGCAACTCGCGTCGCTCGTCGCGCAGGCGACGAGCG
TGGCCGATCATTACTACAAGCTGTCGCAGCAGAACGCGATGCCGGAAGCCGATGCGAAGCAGAAGGCGCTCGAAGCGATC
GCCGCGATGCGCTACGGCAGCGACGGCTACATTTCGATCAACGACTCGAAGCCGGTGATCGTCATGCATCCGATCAAGAC
CGAGCTGAACGGCAAGGACGTGTCGAACTTCGCCGATCCGAACGGCAAGCACCTGTTCGTCGAGATCGTGAAAGTCGGCA
ATGCGGCCGGCGGCAAAGGCTTCGTCGAATATCTGTGGCCGAAACCGGGCGCCGACAAGCCGCAGGACAAGACGAGCGCG
GTCCAGCGTTTCGCGCCGTGGGACTGGTATCTCGTGACCGGCATGTACATGGACGACGTGCGCTCGGCCGTGCTCGCGAG
CATCGGCCGCTGGTTCGGGATGACGGCCGTGCTCGGCGCGATCGCGACCACGGTGATGGTGCTCGTGCTGCGCAGCGTGC
GCGCGAACCTCGGCGGCGAGCTCGAACTGGCGGTCGACACCGCGCGCCGCATCGCGCAGGGCGATCTGACCGCACACGTC
GACGTGAAGCGCGACGATCGCGGCAGCCTGCTGCACGCGCTGCACACGATGCAAAGCGGGCTGATCGACATGGTGTCGCG
CGTGCGCGCCGGCACCGAGAACATCAACGTCGGCGCGAGCGAAATCGCATCGGGCAACACGGACCTGTCGCAGCGCACCG
AGGAACAGGCGGCCGCGCTCGTGCAGACCGCGTCGAGCATGGACCAGATGACGGCCAACGTGAAGCAGAACGCGGAAAGC
GCCGCGCAGGCCGCATCGCTCGCCGATCAGGCGGCGCAGGTCGCGACGCGCGGCAGCGCGGTCGTCGACGACGTGGTGCG
CACGATGAACGAAATCACCGACCGCTCGCACAAGATCGGCGACATCATCGGCGTGATCGACGGCATTGCGTTCCAGACCA
ACATCCTCGCGTTGAACGCGGCGGTCGAAGCCGCGCGTGCCGGCGAACAGGGACGCGGGTTCGCGGTGGTCGCCGCCGAA
GTGCGCTCGCTCGCGCAGCGCTCGGCGACGGCCGCGAAGGAAATCAAGTCGCTGATCGTGTCGTCGAACGAGACGGTCGA
GCAAGGCGCAACGCTCGTCACGCACGCGGGCGAGACGATGGCCGAGATCGTGCAGTCGGTGCGCCGCGTCAATGAGATTC
TCGACGAGATCAGCCACGCGTCGCGCGAACAGAGCGCGGGCATCGAGCAGGTCAATCGCGCGGTCGGCGAAATGGATCAG
GTCACGCAACAGAACGCGGCGCTCGTCGAACAGGCGGCGGCCGCCGCGCACTCGCTGCGCGATCAGGCCGAAGCGCTGCG
CGACGCCGTCACGCGTTTCGCGCTGCCGGCCTGA

Upstream 100 bases:

>100_bases
GGGATTTCCCGCCTACGCCGGCGGCCGCCGCGCGCCGTCAAAAGACTCATCCCGTCACGCCGTTGCGGCACGCCCCGTTC
GACCGACCGACCCAACCACC

Downstream 100 bases:

>100_bases
TCGGCGAACGGCGCCGCGGGCGCGCGATCGCCACGGCAAGCCGACGATCGCGTGCCGGCGGGTGCCGCGCATCGCGGCGT
GCGAGCCGCCGTGTGCGCGC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MRTLTLNQKLASMIVILWLGLLVIAGLGAWQTRASMIDDRREQLASLVAQATSVADHYYKLSQQNAMPEADAKQKALEAI
AAMRYGSDGYISINDSKPVIVMHPIKTELNGKDVSNFADPNGKHLFVEIVKVGNAAGGKGFVEYLWPKPGADKPQDKTSA
VQRFAPWDWYLVTGMYMDDVRSAVLASIGRWFGMTAVLGAIATTVMVLVLRSVRANLGGELELAVDTARRIAQGDLTAHV
DVKRDDRGSLLHALHTMQSGLIDMVSRVRAGTENINVGASEIASGNTDLSQRTEEQAAALVQTASSMDQMTANVKQNAES
AAQAASLADQAAQVATRGSAVVDDVVRTMNEITDRSHKIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAE
VRSLAQRSATAAKEIKSLIVSSNETVEQGATLVTHAGETMAEIVQSVRRVNEILDEISHASREQSAGIEQVNRAVGEMDQ
VTQQNAALVEQAAAAAHSLRDQAEALRDAVTRFALPA

Sequences:

>Translated_517_residues
MRTLTLNQKLASMIVILWLGLLVIAGLGAWQTRASMIDDRREQLASLVAQATSVADHYYKLSQQNAMPEADAKQKALEAI
AAMRYGSDGYISINDSKPVIVMHPIKTELNGKDVSNFADPNGKHLFVEIVKVGNAAGGKGFVEYLWPKPGADKPQDKTSA
VQRFAPWDWYLVTGMYMDDVRSAVLASIGRWFGMTAVLGAIATTVMVLVLRSVRANLGGELELAVDTARRIAQGDLTAHV
DVKRDDRGSLLHALHTMQSGLIDMVSRVRAGTENINVGASEIASGNTDLSQRTEEQAAALVQTASSMDQMTANVKQNAES
AAQAASLADQAAQVATRGSAVVDDVVRTMNEITDRSHKIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAE
VRSLAQRSATAAKEIKSLIVSSNETVEQGATLVTHAGETMAEIVQSVRRVNEILDEISHASREQSAGIEQVNRAVGEMDQ
VTQQNAALVEQAAAAAHSLRDQAEALRDAVTRFALPA
>Mature_517_residues
MRTLTLNQKLASMIVILWLGLLVIAGLGAWQTRASMIDDRREQLASLVAQATSVADHYYKLSQQNAMPEADAKQKALEAI
AAMRYGSDGYISINDSKPVIVMHPIKTELNGKDVSNFADPNGKHLFVEIVKVGNAAGGKGFVEYLWPKPGADKPQDKTSA
VQRFAPWDWYLVTGMYMDDVRSAVLASIGRWFGMTAVLGAIATTVMVLVLRSVRANLGGELELAVDTARRIAQGDLTAHV
DVKRDDRGSLLHALHTMQSGLIDMVSRVRAGTENINVGASEIASGNTDLSQRTEEQAAALVQTASSMDQMTANVKQNAES
AAQAASLADQAAQVATRGSAVVDDVVRTMNEITDRSHKIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAE
VRSLAQRSATAAKEIKSLIVSSNETVEQGATLVTHAGETMAEIVQSVRRVNEILDEISHASREQSAGIEQVNRAVGEMDQ
VTQQNAALVEQAAAAAHSLRDQAEALRDAVTRFALPA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=282, Percent_Identity=59.5744680851064, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI1788194, Length=286, Percent_Identity=58.041958041958, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1788195, Length=290, Percent_Identity=59.6551724137931, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1787690, Length=330, Percent_Identity=52.4242424242424, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1789453, Length=326, Percent_Identity=38.9570552147239, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55230; Mature: 55230

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLTLNQKLASMIVILWLGLLVIAGLGAWQTRASMIDDRREQLASLVAQATSVADHYYK
CCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQQNAMPEADAKQKALEAIAAMRYGSDGYISINDSKPVIVMHPIKTELNGKDVSNFADP
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCC
NGKHLFVEIVKVGNAAGGKGFVEYLWPKPGADKPQDKTSAVQRFAPWDWYLVTGMYMDDV
CCCEEEEEEEHHCCCCCCCCHHHEECCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHH
RSAVLASIGRWFGMTAVLGAIATTVMVLVLRSVRANLGGELELAVDTARRIAQGDLTAHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEE
DVKRDDRGSLLHALHTMQSGLIDMVSRVRAGTENINVGASEIASGNTDLSQRTEEQAAAL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHH
VQTASSMDQMTANVKQNAESAAQAASLADQAAQVATRGSAVVDDVVRTMNEITDRSHKIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRSLAQRSATAAKEIKSLIV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSNETVEQGATLVTHAGETMAEIVQSVRRVNEILDEISHASREQSAGIEQVNRAVGEMDQ
CCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VTQQNAALVEQAAAAAHSLRDQAEALRDAVTRFALPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTLTLNQKLASMIVILWLGLLVIAGLGAWQTRASMIDDRREQLASLVAQATSVADHYYK
CCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQQNAMPEADAKQKALEAIAAMRYGSDGYISINDSKPVIVMHPIKTELNGKDVSNFADP
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCC
NGKHLFVEIVKVGNAAGGKGFVEYLWPKPGADKPQDKTSAVQRFAPWDWYLVTGMYMDDV
CCCEEEEEEEHHCCCCCCCCHHHEECCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHH
RSAVLASIGRWFGMTAVLGAIATTVMVLVLRSVRANLGGELELAVDTARRIAQGDLTAHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEE
DVKRDDRGSLLHALHTMQSGLIDMVSRVRAGTENINVGASEIASGNTDLSQRTEEQAAAL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHH
VQTASSMDQMTANVKQNAESAAQAASLADQAAQVATRGSAVVDDVVRTMNEITDRSHKIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRSLAQRSATAAKEIKSLIV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSNETVEQGATLVTHAGETMAEIVQSVRRVNEILDEISHASREQSAGIEQVNRAVGEMDQ
CCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VTQQNAALVEQAAAAAHSLRDQAEALRDAVTRFALPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]