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The map label for this gene is alsR [H]

Identifier: 189353366

GI number: 189353366

Start: 1615585

End: 1616463

Strand: Reverse

Name: alsR [H]

Synonym: BMULJ_04606

Alternate gene names: 189353366

Gene position: 1616463-1615585 (Counterclockwise)

Preceding gene: 189353370

Following gene: 189353362

Centisome position: 65.36

GC content: 70.42

Gene sequence:

>879_bases
ATGGAACTTCGGCATCTCCGTTATTTTCTGGCCGTGGCCGCCACGTCCAATTTCACGAAGGCCGCGGAAACGCTCGGAAT
CGGGCAGCCGCCGCTCAGTCAGCAGATCAAGGCGCTCGAGAACGAGCTCGGCGTCGAACTGTTCAGGCGCACCGCGCGTG
GCGCCGAACTGACGACGGCCGGCGAAGTGTTCCGCGACGAGGCGCGCCGCGTGCTCGACGACGCGGAACGCGCATCGCGC
GCGGCAAGGCGCGCCGCACGCGGCGAAATCGGGCATCTGCGCGTCGGCTTCACCGGGACGGCCGCGTTCAATTCGAAGGT
GTCCGATCTGCTGCGTCGTTTCCGCGAAGCGTTTCCGCAGGCCGAGCTCACGTTGCTCGAAGCGACGTCCGGCGTGCTGT
TCGCCGAGCTCGAAGCGGGGCGGCTCGACGTCGCGCTGGTGCGACCGCGGCAGCGCATTGCTCCCGTGCTGCGCATCGCG
GAGTGGGACGAGGAGCCGATGTTCGTTGCGCTGCCGGTCGCGCATCGGCTCGCGCGGAGGCGCCAGATCGCGCTCGCGGA
GCTCGCCGACGAGTCGTTCGTGCAGGTGCCGCGCGAGGCCGGGAGTACGCTGTTCGACGACATCGTCGCCGCGTGCAATG
CGGCCGGGTTCCAGCCGCGGATGGCGCAGCCGGCCCCGCAGATGGCGTCTGCGGTCACGCTGGTCGCCGCGGGCCTCGGC
GTCTCGCTGGTCCCCGATGCAATCACGCAGGTGCGGATTGCCGGCGTCGTCTATCGTCCGATCGCGGACGCCGCGCTGCG
CGCGCGGCTCGGCGTCGCGTCGCGCGCCGACGATCCGTCGCCGGTCGTGCGCAACTTTCTGCAGCTCGCGCTCGGCTAG

Upstream 100 bases:

>100_bases
GCACATATGTCCAATATATGAAAAGAACCGCAACCATATGTTTTTCCACTGGCTGCGGCGTGCCCACCGGTATCTCCGCC
ACGGACGCAGGACGCAACGC

Downstream 100 bases:

>100_bases
GGCTAGCGCCCGCGTCGCGCGCTCACGCGTGCCGTTCGCCGACGCGGTTTTCTTCGGGGCTATAGACGGTCAACCCTTCG
GTCGGATCCATCGGCATCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MELRHLRYFLAVAATSNFTKAAETLGIGQPPLSQQIKALENELGVELFRRTARGAELTTAGEVFRDEARRVLDDAERASR
AARRAARGEIGHLRVGFTGTAAFNSKVSDLLRRFREAFPQAELTLLEATSGVLFAELEAGRLDVALVRPRQRIAPVLRIA
EWDEEPMFVALPVAHRLARRRQIALAELADESFVQVPREAGSTLFDDIVAACNAAGFQPRMAQPAPQMASAVTLVAAGLG
VSLVPDAITQVRIAGVVYRPIADAALRARLGVASRADDPSPVVRNFLQLALG

Sequences:

>Translated_292_residues
MELRHLRYFLAVAATSNFTKAAETLGIGQPPLSQQIKALENELGVELFRRTARGAELTTAGEVFRDEARRVLDDAERASR
AARRAARGEIGHLRVGFTGTAAFNSKVSDLLRRFREAFPQAELTLLEATSGVLFAELEAGRLDVALVRPRQRIAPVLRIA
EWDEEPMFVALPVAHRLARRRQIALAELADESFVQVPREAGSTLFDDIVAACNAAGFQPRMAQPAPQMASAVTLVAAGLG
VSLVPDAITQVRIAGVVYRPIADAALRARLGVASRADDPSPVVRNFLQLALG
>Mature_292_residues
MELRHLRYFLAVAATSNFTKAAETLGIGQPPLSQQIKALENELGVELFRRTARGAELTTAGEVFRDEARRVLDDAERASR
AARRAARGEIGHLRVGFTGTAAFNSKVSDLLRRFREAFPQAELTLLEATSGVLFAELEAGRLDVALVRPRQRIAPVLRIA
EWDEEPMFVALPVAHRLARRRQIALAELADESFVQVPREAGSTLFDDIVAACNAAGFQPRMAQPAPQMASAVTLVAAGLG
VSLVPDAITQVRIAGVVYRPIADAALRARLGVASRADDPSPVVRNFLQLALG

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=287, Percent_Identity=38.6759581881533, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1788887, Length=289, Percent_Identity=37.7162629757785, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI2367136, Length=260, Percent_Identity=33.0769230769231, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=30.8219178082192, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI157672245, Length=251, Percent_Identity=35.8565737051793, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788297, Length=169, Percent_Identity=34.3195266272189, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693105, Length=282, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081904, Length=148, Percent_Identity=34.4594594594595, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787530, Length=271, Percent_Identity=27.3062730627306, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788296, Length=230, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=29.9319727891156, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789506, Length=165, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=27.3092369477912, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=30.8219178082192, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31638; Mature: 31638

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLRYFLAVAATSNFTKAAETLGIGQPPLSQQIKALENELGVELFRRTARGAELTTA
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GEVFRDEARRVLDDAERASRAARRAARGEIGHLRVGFTGTAAFNSKVSDLLRRFREAFPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCC
AELTLLEATSGVLFAELEAGRLDVALVRPRQRIAPVLRIAEWDEEPMFVALPVAHRLARR
HHEEEEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
RQIALAELADESFVQVPREAGSTLFDDIVAACNAAGFQPRMAQPAPQMASAVTLVAAGLG
HHHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
VSLVPDAITQVRIAGVVYRPIADAALRARLGVASRADDPSPVVRNFLQLALG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MELRHLRYFLAVAATSNFTKAAETLGIGQPPLSQQIKALENELGVELFRRTARGAELTTA
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GEVFRDEARRVLDDAERASRAARRAARGEIGHLRVGFTGTAAFNSKVSDLLRRFREAFPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCC
AELTLLEATSGVLFAELEAGRLDVALVRPRQRIAPVLRIAEWDEEPMFVALPVAHRLARR
HHEEEEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
RQIALAELADESFVQVPREAGSTLFDDIVAACNAAGFQPRMAQPAPQMASAVTLVAAGLG
HHHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
VSLVPDAITQVRIAGVVYRPIADAALRARLGVASRADDPSPVVRNFLQLALG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]