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The map label for this gene is ndh [H]

Identifier: 189353336

GI number: 189353336

Start: 1576735

End: 1578027

Strand: Direct

Name: ndh [H]

Synonym: BMULJ_04576

Alternate gene names: 189353336

Gene position: 1576735-1578027 (Clockwise)

Preceding gene: 189353334

Following gene: 189353337

Centisome position: 63.75

GC content: 68.6

Gene sequence:

>1293_bases
ATGACAACCCCTACTCGCATCGTGATCGTCGGCGGCGGGATCGCCGGATTGCAGCTCGCCACGCGTCTGGGCGAACGGCT
CGGCAAGTCCGGCCGCGCGCAGGTCACGGTCGTCGACCGCAGCCCGACCCACGTGTGGAAGCCGATGCTGCACACGATCG
CGGCCGGCACGCGCGACGTGCAGCAACAGCAGGTGATCTTCGTCGCGCATGCGTGCGAGCACGGTTACACGTATCAGCCC
GGCGAGCTTCAAGGGCTCGACCGCACTCGCCGGCGCGTGCGGCTCGGCGAGATCCGTTCCCAGGACGGCGCAGTGGTGCT
CGAGGCGCGCGAGCTCGAATACGACGTGCTGATCCTCGCGCTCGGCAGCCAGGCCAACGACTTCGGCGTACCGGGCGTGC
GCGAGCATTGCTATTTCATCGACAGCCAGCGTCAGGCCGAGGCCTTCAACGAAGCGTTGCGGATGCGCGTGTTTCGCAGC
GTGGCGCGCGACGAAGCGCTGCGCGTCGCGATCGTCGGCGCGGGCGCGACCGGCGTCGAGCTCGCGGCGGAACTGAGCCG
GCTGCTCGAAGTCGCGCAGGCGTACGGCGATGCAACCGTCCGCGAGCGGCTGCAGCTCACGCTGCTCGAAAGCGGCCCGC
GCATCCTCGCCGCGTTTCCGCCGAAGATTTCCGCGTCGGCGCAGCAACAGCTCGAACGGATCGGCTTCCGGGTGCTGACG
TCCACGCGCGTGACGTCGGCCGCGCCGAACGGCTTCCACTACGGCGACGATTCTTTTGCCGAAGCGGACCTGATGGTGTG
GGCGGCGGGCGTGAAAGCGCCCGAGTTCATGCAGGCGCTCGGCGGCCTCGACACGAATCGCGCGAACCAGATCGTCGTCG
GCCCGACGCTGCAGGCAACGGCCGACGAGCACATCTTCGCGATCGGCGATTGCGCGAGCCTGCTGCCCGACGGCCAGGAG
CGGCCGCTGCCGCCAACCGCGCAGGTCGCGACGCAGCAGGCCGAACATCTGGCGAAGCATCTGCCGGCATGGCTCGACGG
CAAGCCGATGCCGGCTTTCGCGTTCCACGACTTCGGTGCGCTCGTATCGCTGAGCGACTACGACGCGTTCGGCACGCTCG
GGCAGTTCGGCTTCTTTCGCGGCGGGTTCATTCGCGGCCGGTTCGCGCAACTCAGTCATCTGATGCTGTACCGGCGACAC
CAGCAGGCGCTGCACGGGGTCCGCAAGGCCACGATGCTGTGGATCGCCGAACGCATCAACGGCTGCGTGCAGCCGCGCAT
CCGCCTGTCCTGA

Upstream 100 bases:

>100_bases
GTTTCATGCGATCAGAAAAACGGGGCCGGCTCGACTCCGTTGACACCCGGAGCCCGAAAGCGCTAGGATCATACATTATT
CATCACTTGATGATTTATTC

Downstream 100 bases:

>100_bases
TGCCGTGCGCCCGGCATCGCATAGTGTTTCGAGGAAAACAGACATGGACAACAGTGCAACATCCTGGATCAGAACCGTCG
CCGAGATCGGCAGCTTCGAC

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTTPTRIVIVGGGIAGLQLATRLGERLGKSGRAQVTVVDRSPTHVWKPMLHTIAAGTRDVQQQQVIFVAHACEHGYTYQP
GELQGLDRTRRRVRLGEIRSQDGAVVLEARELEYDVLILALGSQANDFGVPGVREHCYFIDSQRQAEAFNEALRMRVFRS
VARDEALRVAIVGAGATGVELAAELSRLLEVAQAYGDATVRERLQLTLLESGPRILAAFPPKISASAQQQLERIGFRVLT
STRVTSAAPNGFHYGDDSFAEADLMVWAAGVKAPEFMQALGGLDTNRANQIVVGPTLQATADEHIFAIGDCASLLPDGQE
RPLPPTAQVATQQAEHLAKHLPAWLDGKPMPAFAFHDFGALVSLSDYDAFGTLGQFGFFRGGFIRGRFAQLSHLMLYRRH
QQALHGVRKATMLWIAERINGCVQPRIRLS

Sequences:

>Translated_430_residues
MTTPTRIVIVGGGIAGLQLATRLGERLGKSGRAQVTVVDRSPTHVWKPMLHTIAAGTRDVQQQQVIFVAHACEHGYTYQP
GELQGLDRTRRRVRLGEIRSQDGAVVLEARELEYDVLILALGSQANDFGVPGVREHCYFIDSQRQAEAFNEALRMRVFRS
VARDEALRVAIVGAGATGVELAAELSRLLEVAQAYGDATVRERLQLTLLESGPRILAAFPPKISASAQQQLERIGFRVLT
STRVTSAAPNGFHYGDDSFAEADLMVWAAGVKAPEFMQALGGLDTNRANQIVVGPTLQATADEHIFAIGDCASLLPDGQE
RPLPPTAQVATQQAEHLAKHLPAWLDGKPMPAFAFHDFGALVSLSDYDAFGTLGQFGFFRGGFIRGRFAQLSHLMLYRRH
QQALHGVRKATMLWIAERINGCVQPRIRLS
>Mature_429_residues
TTPTRIVIVGGGIAGLQLATRLGERLGKSGRAQVTVVDRSPTHVWKPMLHTIAAGTRDVQQQQVIFVAHACEHGYTYQPG
ELQGLDRTRRRVRLGEIRSQDGAVVLEARELEYDVLILALGSQANDFGVPGVREHCYFIDSQRQAEAFNEALRMRVFRSV
ARDEALRVAIVGAGATGVELAAELSRLLEVAQAYGDATVRERLQLTLLESGPRILAAFPPKISASAQQQLERIGFRVLTS
TRVTSAAPNGFHYGDDSFAEADLMVWAAGVKAPEFMQALGGLDTNRANQIVVGPTLQATADEHIFAIGDCASLLPDGQER
PLPPTAQVATQQAEHLAKHLPAWLDGKPMPAFAFHDFGALVSLSDYDAFGTLGQFGFFRGGFIRGRFAQLSHLMLYRRHQ
QALHGVRKATMLWIAERINGCVQPRIRLS

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=435, Percent_Identity=44.367816091954, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1789065, Length=271, Percent_Identity=29.1512915129151, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323515, Length=445, Percent_Identity=24.9438202247191, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323794, Length=359, Percent_Identity=27.2980501392758, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320118, Length=355, Percent_Identity=25.0704225352113, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47034; Mature: 46903

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPTRIVIVGGGIAGLQLATRLGERLGKSGRAQVTVVDRSPTHVWKPMLHTIAAGTRDV
CCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHH
QQQQVIFVAHACEHGYTYQPGELQGLDRTRRRVRLGEIRSQDGAVVLEARELEYDVLILA
HHHHEEEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEE
LGSQANDFGVPGVREHCYFIDSQRQAEAFNEALRMRVFRSVARDEALRVAIVGAGATGVE
ECCCCCCCCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH
LAAELSRLLEVAQAYGDATVRERLQLTLLESGPRILAAFPPKISASAQQQLERIGFRVLT
HHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHEE
STRVTSAAPNGFHYGDDSFAEADLMVWAAGVKAPEFMQALGGLDTNRANQIVVGPTLQAT
CCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCCCCC
ADEHIFAIGDCASLLPDGQERPLPPTAQVATQQAEHLAKHLPAWLDGKPMPAFAFHDFGA
CCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEHECCCCC
LVSLSDYDAFGTLGQFGFFRGGFIRGRFAQLSHLMLYRRHQQALHGVRKATMLWIAERIN
EEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCVQPRIRLS
HHCCCCEECC
>Mature Secondary Structure 
TTPTRIVIVGGGIAGLQLATRLGERLGKSGRAQVTVVDRSPTHVWKPMLHTIAAGTRDV
CCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHH
QQQQVIFVAHACEHGYTYQPGELQGLDRTRRRVRLGEIRSQDGAVVLEARELEYDVLILA
HHHHEEEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEE
LGSQANDFGVPGVREHCYFIDSQRQAEAFNEALRMRVFRSVARDEALRVAIVGAGATGVE
ECCCCCCCCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHH
LAAELSRLLEVAQAYGDATVRERLQLTLLESGPRILAAFPPKISASAQQQLERIGFRVLT
HHHHHHHHHHHHHHHCCHHHHHHHHEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHEE
STRVTSAAPNGFHYGDDSFAEADLMVWAAGVKAPEFMQALGGLDTNRANQIVVGPTLQAT
CCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCCCCC
ADEHIFAIGDCASLLPDGQERPLPPTAQVATQQAEHLAKHLPAWLDGKPMPAFAFHDFGA
CCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEHECCCCC
LVSLSDYDAFGTLGQFGFFRGGFIRGRFAQLSHLMLYRRHQQALHGVRKATMLWIAERIN
EEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCVQPRIRLS
HHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]