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The map label for this gene is soxR [H]

Identifier: 189353332

GI number: 189353332

Start: 1573609

End: 1574088

Strand: Direct

Name: soxR [H]

Synonym: BMULJ_04572

Alternate gene names: 189353332

Gene position: 1573609-1574088 (Clockwise)

Preceding gene: 189353327

Following gene: 189353334

Centisome position: 63.63

GC content: 66.46

Gene sequence:

>480_bases
ATGGGTATCCAGGAAGTTCCGCAATGGCCGCTGATGTCGATCCGCGAAGTCGCCGCGCGCAGCGGCGTGCCGGCTTCGAC
GCTGCGCTTCTATGAAGCGCGCGGACTCATCAAGTCGCACCGGAACGGGTCGAGCCACCGTCACTATTCGCGCGCCGTGC
TGCGGCTGATCGCATTCATCGTGTTCGCGCAGAAGATCGGCTATACGCTCGACGAAATCGCCGAGCAGCTCGTGAGCCTG
CCGGAAGATACCGCGCCGACGAACAAGGACTGGCAGCGGCTGTCGCGCGGCTGGAAGCAGCGCGTCGCCAGCCGCATCGA
GGAATTGCAGCGGCTTTACATCAACCTCGACGAATGCATCGGCTGCGGCTGCCTGTCGCTGAAGCGCTGCAAGCTGACCA
ATCCCGAGGACCGCGCGGGCCGCAACGGGCCCGGCGCGCGGCGCTGGCTCGGCGATCCGCCGCCGGCCGTTCCGGAATGA

Upstream 100 bases:

>100_bases
GCGGAAAGAGAGGGAGAGCATGTTGCCTCGCGACGGGTTAAACTGCCGCGTAGCTTAAAAGTTCAAGTTAACTTCAAGTC
AAGCTTTCCCGGAGGGCATC

Downstream 100 bases:

>100_bases
AGTGCGTGATGCGGATCACGGCCGGCGCCGGCCGGCATGTCACCCGACCCGCCAGCCGCCGTTCACCGCAATCGTCGCGC
CCGTGACGAACGCCGCGCGC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MGIQEVPQWPLMSIREVAARSGVPASTLRFYEARGLIKSHRNGSSHRHYSRAVLRLIAFIVFAQKIGYTLDEIAEQLVSL
PEDTAPTNKDWQRLSRGWKQRVASRIEELQRLYINLDECIGCGCLSLKRCKLTNPEDRAGRNGPGARRWLGDPPPAVPE

Sequences:

>Translated_159_residues
MGIQEVPQWPLMSIREVAARSGVPASTLRFYEARGLIKSHRNGSSHRHYSRAVLRLIAFIVFAQKIGYTLDEIAEQLVSL
PEDTAPTNKDWQRLSRGWKQRVASRIEELQRLYINLDECIGCGCLSLKRCKLTNPEDRAGRNGPGARRWLGDPPPAVPE
>Mature_158_residues
GIQEVPQWPLMSIREVAARSGVPASTLRFYEARGLIKSHRNGSSHRHYSRAVLRLIAFIVFAQKIGYTLDEIAEQLVSLP
EDTAPTNKDWQRLSRGWKQRVASRIEELQRLYINLDECIGCGCLSLKRCKLTNPEDRAGRNGPGARRWLGDPPPAVPE

Specific function: Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron-sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster i

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790498, Length=137, Percent_Identity=48.9051094890511, Blast_Score=126, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR010211
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17978; Mature: 17847

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIQEVPQWPLMSIREVAARSGVPASTLRFYEARGLIKSHRNGSSHRHYSRAVLRLIAFI
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VFAQKIGYTLDEIAEQLVSLPEDTAPTNKDWQRLSRGWKQRVASRIEELQRLYINLDECI
HHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCGCLSLKRCKLTNPEDRAGRNGPGARRWLGDPPPAVPE
CCCHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GIQEVPQWPLMSIREVAARSGVPASTLRFYEARGLIKSHRNGSSHRHYSRAVLRLIAFI
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VFAQKIGYTLDEIAEQLVSLPEDTAPTNKDWQRLSRGWKQRVASRIEELQRLYINLDECI
HHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCGCLSLKRCKLTNPEDRAGRNGPGARRWLGDPPPAVPE
CCCHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9045804; 10984043 [H]