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The map label for this gene is nodT [H]

Identifier: 189353329

GI number: 189353329

Start: 1567668

End: 1569143

Strand: Reverse

Name: nodT [H]

Synonym: BMULJ_04569

Alternate gene names: 189353329

Gene position: 1569143-1567668 (Counterclockwise)

Preceding gene: 189353330

Following gene: 189353328

Centisome position: 63.45

GC content: 72.76

Gene sequence:

>1476_bases
ATGAGCGCCGCATTCCGATTTTCAGCGCTCGCGATGGCCGCGATGCTGTCGGCGTGTGCCGTCGGCCCGGACTTCGTGCG
GCCCGATACGGTCACGGCCGCACGCTTCGCGCGCGACGCGCATCCGGCGACGCAGGACGGCTCGCCGCCCGATGCGTCGG
CCGATGCCGACGCCGCATTCTGGCGCGGCTTCGGCGATCCGGCGCTGAGCGCGTTGATCGAGGCCGCGCTCGCCGCGAAC
CAGGATCTGGCGCTGGCGGTGTCGCGCTACGACGCATCGAACGCGCTGCTGTCGCAGGCGCGCTTCGATCGCTATCCGAC
GGTCACCGCGAGCGGCCGGATCGGCCATCAGCTGACGAGCAAGGATCAGGCGTTCGGCGCGCCGCGCAGCGAGCGCGACA
CGTCGATTTCGAGCGTCGGCATCAACGCCGGTTGGGAGCTCGATCTGTTCGGCCGCGTGCGCCGTTCGATCGAATCGCAG
CGCGCCGAAACGGCCGCGAGCGCGGCCGACGTGCGCGCCGTGCGGGTCGCGATCGCGGCCGAGGTCGCGGCCACGTACGT
CGACTTGCGCGGCTCGCAGGAACGGCTGCGGATCGCGCGCGACAACGCCGCGAACCAGCAGCAGACGCTCGCGCTGATCA
ATGCGCGCGTCGCCGCGGGCCGCGGCTCCGAGCTCGATGCGGCGCGCGCACGCGCGCAGTACGAGGCGACGACCTCGCGG
ATCGCCGTCTATGAAGCGGCGATCGGTGTCGACGAGCATCGGCTCGCGGTGCTGACCGGACAGCGGCCCGATGCGCTGGT
CGGTCGATTCGACGTGCCGGCCGGCGCGCCGTTGCCGACGCTTGCCGCCGACGTCGATCCCGGCACGCCCGGTGATCTGC
TGCGCCGGCGTCCCGACGTCGCGGCGGCCGAGGCGCGGCTGCATGCGGCGACCGCGCGGATCGGCGTCGCGACGGCCGAT
TTGTTTCCGCGCTTCACGCTGTCGGGCCTGCTCGGCAGCGCGACGAGCAGCTACGGATTTTTCCGCGCGGGCAGCGACAC
GAACCTGATCGCACTCGGCATCGACTGGTCGTTTCTGGACGTCGGCCGCGTGCGCGCGCGCATCGCCGCAAGCGACGCCG
AAGCGGCGGGACAGCTCGCGCAATACCGGCAAACCGTGCTCGGCGCGCTCGAAGAGACCGAGAACGCGTTGTTGCGCGTC
GCCCGCACGCGCGACGAGGCCGCGCATCTGACGCGCGCGGCCGCCGACAGCGCGCGCGCCGCGCAGCTCGCGCAGACGCG
GTTTTCGGCCGGTGCGATCGACTACTACGAAGTGCTCGATGCACAGCGCACGCTGCTGCAGGCGCAGGATGCGGCGGCCG
ACGGCCGGATGCGCAGCGCCGCGTCGACGGTCGCGCTGTACAAGGCGCTCGCCGGCGGATGGCCGCCTTTGGCCGGGGCG
CGCGAACCGGCGCAGCGGGCGGACGCGCGGCCTTAG

Upstream 100 bases:

>100_bases
TGTTCCTGACGCCGGTGTTCTACGTGACGATCCGCAAGCTCGCGGGCGGCACGCCGACCGTGTGGCACGAACAGCACGGC
ACGCTGGAAGGAGAGAACCG

Downstream 100 bases:

>100_bases
CGGTCGCTGCGGCGGGTGCGGTGGTCGCGGTCGCCAGGTTGCCAGGTCGTCGCAGCGGGGCGCGCCGCCTGCGGACGACC
GGTTCGCGCCCGCCGCCGCA

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSAAFRFSALAMAAMLSACAVGPDFVRPDTVTAARFARDAHPATQDGSPPDASADADAAFWRGFGDPALSALIEAALAAN
QDLALAVSRYDASNALLSQARFDRYPTVTASGRIGHQLTSKDQAFGAPRSERDTSISSVGINAGWELDLFGRVRRSIESQ
RAETAASAADVRAVRVAIAAEVAATYVDLRGSQERLRIARDNAANQQQTLALINARVAAGRGSELDAARARAQYEATTSR
IAVYEAAIGVDEHRLAVLTGQRPDALVGRFDVPAGAPLPTLAADVDPGTPGDLLRRRPDVAAAEARLHAATARIGVATAD
LFPRFTLSGLLGSATSSYGFFRAGSDTNLIALGIDWSFLDVGRVRARIAASDAEAAGQLAQYRQTVLGALEETENALLRV
ARTRDEAAHLTRAAADSARAAQLAQTRFSAGAIDYYEVLDAQRTLLQAQDAAADGRMRSAASTVALYKALAGGWPPLAGA
REPAQRADARP

Sequences:

>Translated_491_residues
MSAAFRFSALAMAAMLSACAVGPDFVRPDTVTAARFARDAHPATQDGSPPDASADADAAFWRGFGDPALSALIEAALAAN
QDLALAVSRYDASNALLSQARFDRYPTVTASGRIGHQLTSKDQAFGAPRSERDTSISSVGINAGWELDLFGRVRRSIESQ
RAETAASAADVRAVRVAIAAEVAATYVDLRGSQERLRIARDNAANQQQTLALINARVAAGRGSELDAARARAQYEATTSR
IAVYEAAIGVDEHRLAVLTGQRPDALVGRFDVPAGAPLPTLAADVDPGTPGDLLRRRPDVAAAEARLHAATARIGVATAD
LFPRFTLSGLLGSATSSYGFFRAGSDTNLIALGIDWSFLDVGRVRARIAASDAEAAGQLAQYRQTVLGALEETENALLRV
ARTRDEAAHLTRAAADSARAAQLAQTRFSAGAIDYYEVLDAQRTLLQAQDAAADGRMRSAASTVALYKALAGGWPPLAGA
REPAQRADARP
>Mature_490_residues
SAAFRFSALAMAAMLSACAVGPDFVRPDTVTAARFARDAHPATQDGSPPDASADADAAFWRGFGDPALSALIEAALAANQ
DLALAVSRYDASNALLSQARFDRYPTVTASGRIGHQLTSKDQAFGAPRSERDTSISSVGINAGWELDLFGRVRRSIESQR
AETAASAADVRAVRVAIAAEVAATYVDLRGSQERLRIARDNAANQQQTLALINARVAAGRGSELDAARARAQYEATTSRI
AVYEAAIGVDEHRLAVLTGQRPDALVGRFDVPAGAPLPTLAADVDPGTPGDLLRRRPDVAAAEARLHAATARIGVATADL
FPRFTLSGLLGSATSSYGFFRAGSDTNLIALGIDWSFLDVGRVRARIAASDAEAAGQLAQYRQTVLGALEETENALLRVA
RTRDEAAHLTRAAADSARAAQLAQTRFSAGAIDYYEVLDAQRTLLQAQDAAADGRMRSAASTVALYKALAGGWPPLAGAR
EPAQRADARP

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=469, Percent_Identity=27.7185501066098, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI2367348, Length=496, Percent_Identity=23.991935483871, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51596; Mature: 51465

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAFRFSALAMAAMLSACAVGPDFVRPDTVTAARFARDAHPATQDGSPPDASADADAAF
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
WRGFGDPALSALIEAALAANQDLALAVSRYDASNALLSQARFDRYPTVTASGRIGHQLTS
HHCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCCHHCC
KDQAFGAPRSERDTSISSVGINAGWELDLFGRVRRSIESQRAETAASAADVRAVRVAIAA
CHHHCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAATYVDLRGSQERLRIARDNAANQQQTLALINARVAAGRGSELDAARARAQYEATTSR
HHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAVYEAAIGVDEHRLAVLTGQRPDALVGRFDVPAGAPLPTLAADVDPGTPGDLLRRRPDV
HEEHHHHCCCCCCEEEEEECCCCCHHEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCH
AAAEARLHAATARIGVATADLFPRFTLSGLLGSATSSYGFFRAGSDTNLIALGIDWSFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCHHH
VGRVRARIAASDAEAAGQLAQYRQTVLGALEETENALLRVARTRDEAAHLTRAAADSARA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLAQTRFSAGAIDYYEVLDAQRTLLQAQDAAADGRMRSAASTVALYKALAGGWPPLAGA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
REPAQRADARP
CCCHHHCCCCC
>Mature Secondary Structure 
SAAFRFSALAMAAMLSACAVGPDFVRPDTVTAARFARDAHPATQDGSPPDASADADAAF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
WRGFGDPALSALIEAALAANQDLALAVSRYDASNALLSQARFDRYPTVTASGRIGHQLTS
HHCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCCHHCC
KDQAFGAPRSERDTSISSVGINAGWELDLFGRVRRSIESQRAETAASAADVRAVRVAIAA
CHHHCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAATYVDLRGSQERLRIARDNAANQQQTLALINARVAAGRGSELDAARARAQYEATTSR
HHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAVYEAAIGVDEHRLAVLTGQRPDALVGRFDVPAGAPLPTLAADVDPGTPGDLLRRRPDV
HEEHHHHCCCCCCEEEEEECCCCCHHEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCH
AAAEARLHAATARIGVATADLFPRFTLSGLLGSATSSYGFFRAGSDTNLIALGIDWSFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCHHH
VGRVRARIAASDAEAAGQLAQYRQTVLGALEETENALLRVARTRDEAAHLTRAAADSARA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLAQTRFSAGAIDYYEVLDAQRTLLQAQDAAADGRMRSAASTVALYKALAGGWPPLAGA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
REPAQRADARP
CCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]