BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fabG [H]

Identifier: 189353313

GI number: 189353313

Start: 1551422

End: 1552132

Strand: Reverse

Name: fabG [H]

Synonym: BMULJ_04553

Alternate gene names: 189353313

Gene position: 1552132-1551422 (Counterclockwise)

Preceding gene: 189353315

Following gene: 189353311

Centisome position: 62.76

GC content: 61.74

Gene sequence:

>711_bases
ATGAATACATCGAAGAAGGTTGTGGTCGTCACCGGTGCATCTCAGGGCATCGGCGCGAAAGTCGTCGACGCCTTTCGACG
GCTCGACTACCGCGTCGTCGCGACCTCGCGGTCGATCAAGCCTTCGAACGACGACGACATGCTCTGTATCGCCGGCGACA
TCGGCGATCGAGCGACGGCCCGTCGCGTGATTGCCGAAGGCATCGCGCGGTTCGGGCGAATCGATACGCTGGTCAACAAC
GCGGGCCTTTACATCGGCAGGCCGTTCACCGAGCACACGGCTGAAGACTATGCAGCGGTGATGAACGTCAACATGGCGGG
TTTTTATCACGTCACGCAGCTCGCGATCGCCGAGATGGAAAAGCATGGAAGCGGCCACGTGGTGAGCGTCACGGCAAGCA
TCGACCAGGTCGCGATCGGCGGCGTCTACTCGGTGCTGGCTGCGTTGACGAAGGGCGGCATCAATGCGGCGACGAAGTCG
CTCGCGATCGAATATGCAAAGAAGGGGATTCGCGTCAACGCCGTTGCGCCCGGCAACATCAAAACACCGATGCACGCGCC
GGAACTCCATGAAGCGCTGAGCGCGTTCAATCCTGTCGGCCGCCTCGGCGAAGCGAGCGATATCGCCGACGCGATCCTGT
TTCTCGACGCAGCACCGTTCATCACCGGCGAGATCCTCCATGTGGACGGCGGGCAGAGCGCGGGTCATTGA

Upstream 100 bases:

>100_bases
CAATCTTGGTTCTTCCGCGCGCACAGTCGATGATGAAGAATGACAAGACGGCACGGCGGAGTGCAGCCGTGGTTCTTTGT
CCGATCCTCGCGGGTAAAGC

Downstream 100 bases:

>100_bases
GATGCGCGATCTGTCGAATGCCGACGAGACGACCGGCCGAACCGCGCGATGCGCTACTGCGGCGCGTCGAGTTTGGCGGC
GGCATCCATGAGCGCGGTAC

Product: putative short-chain alcohol dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MNTSKKVVVVTGASQGIGAKVVDAFRRLDYRVVATSRSIKPSNDDDMLCIAGDIGDRATARRVIAEGIARFGRIDTLVNN
AGLYIGRPFTEHTAEDYAAVMNVNMAGFYHVTQLAIAEMEKHGSGHVVSVTASIDQVAIGGVYSVLAALTKGGINAATKS
LAIEYAKKGIRVNAVAPGNIKTPMHAPELHEALSAFNPVGRLGEASDIADAILFLDAAPFITGEILHVDGGQSAGH

Sequences:

>Translated_236_residues
MNTSKKVVVVTGASQGIGAKVVDAFRRLDYRVVATSRSIKPSNDDDMLCIAGDIGDRATARRVIAEGIARFGRIDTLVNN
AGLYIGRPFTEHTAEDYAAVMNVNMAGFYHVTQLAIAEMEKHGSGHVVSVTASIDQVAIGGVYSVLAALTKGGINAATKS
LAIEYAKKGIRVNAVAPGNIKTPMHAPELHEALSAFNPVGRLGEASDIADAILFLDAAPFITGEILHVDGGQSAGH
>Mature_236_residues
MNTSKKVVVVTGASQGIGAKVVDAFRRLDYRVVATSRSIKPSNDDDMLCIAGDIGDRATARRVIAEGIARFGRIDTLVNN
AGLYIGRPFTEHTAEDYAAVMNVNMAGFYHVTQLAIAEMEKHGSGHVVSVTASIDQVAIGGVYSVLAALTKGGINAATKS
LAIEYAKKGIRVNAVAPGNIKTPMHAPELHEALSAFNPVGRLGEASDIADAILFLDAAPFITGEILHVDGGQSAGH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=32.0512820512821, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI59889578, Length=207, Percent_Identity=33.8164251207729, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=33.0543933054393, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.968253968254, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=28.4552845528455, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=31.8725099601594, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI15277342, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=31.0880829015544, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI66933014, Length=245, Percent_Identity=29.7959183673469, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=30, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4503301, Length=247, Percent_Identity=26.7206477732794, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=33.4710743801653, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=32, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=30.7053941908714, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788459, Length=189, Percent_Identity=31.2169312169312, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790717, Length=167, Percent_Identity=32.9341317365269, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.5081967213115, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=30.0395256916996, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=29.4573643410853, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=25.3112033195021, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=28.1767955801105, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=26.4227642276423, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=235, Percent_Identity=25.531914893617, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=31.6205533596838, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=30.7086614173228, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=31.8181818181818, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=33.469387755102, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=32.0610687022901, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=30.1587301587302, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=27.3076923076923, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.811320754717, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=26.0377358490566, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=28.6259541984733, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=29.7619047619048, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=27.1653543307087, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=25.4752851711027, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=27.7153558052434, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=26.4150943396226, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.9693486590038, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=27.8884462151394, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=28.3524904214559, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=27.9693486590038, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=28.6821705426357, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.9961977186312, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=26.4150943396226, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=191, Percent_Identity=27.7486910994764, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=33.976833976834, Blast_Score=120, Evalue=7e-28,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=33.2, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.6771653543307, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=32.6771653543307, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=30.7053941908714, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=30.1652892561983, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=30.3501945525292, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=28.8461538461538, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356301, Length=191, Percent_Identity=31.9371727748691, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737361, Length=245, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641232, Length=235, Percent_Identity=25.9574468085106, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24724; Mature: 24724

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSKKVVVVTGASQGIGAKVVDAFRRLDYRVVATSRSIKPSNDDDMLCIAGDIGDRATA
CCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
RRVIAEGIARFGRIDTLVNNAGLYIGRPFTEHTAEDYAAVMNVNMAGFYHVTQLAIAEME
HHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KHGSGHVVSVTASIDQVAIGGVYSVLAALTKGGINAATKSLAIEYAKKGIRVNAVAPGNI
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
KTPMHAPELHEALSAFNPVGRLGEASDIADAILFLDAAPFITGEILHVDGGQSAGH
CCCCCCHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MNTSKKVVVVTGASQGIGAKVVDAFRRLDYRVVATSRSIKPSNDDDMLCIAGDIGDRATA
CCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
RRVIAEGIARFGRIDTLVNNAGLYIGRPFTEHTAEDYAAVMNVNMAGFYHVTQLAIAEME
HHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KHGSGHVVSVTASIDQVAIGGVYSVLAALTKGGINAATKSLAIEYAKKGIRVNAVAPGNI
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
KTPMHAPELHEALSAFNPVGRLGEASDIADAILFLDAAPFITGEILHVDGGQSAGH
CCCCCCHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]