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The map label for this gene is mdtO [H]

Identifier: 189353288

GI number: 189353288

Start: 1525050

End: 1527212

Strand: Direct

Name: mdtO [H]

Synonym: BMULJ_04528

Alternate gene names: 189353288

Gene position: 1525050-1527212 (Clockwise)

Preceding gene: 189353287

Following gene: 189353289

Centisome position: 61.66

GC content: 70.92

Gene sequence:

>2163_bases
ATGGCGCAGCCTGCCGCTGAGGTCCGCTCGCCCGGCCTGCGCGAAGTCCTGCGACTGCTCGCGCCGTTTCCGGGACGCAC
GGCGATCGCCGTGCGCGTCGCGCTGATCTGCACGCTGACCGTGCTGGTGACGAGCGCGTACGGCACACCCGAAGCCGCGC
TGTCCGCGTACGTCGTGTTCTTCATGATCCGCGCCGACCGCGTGACGAGCATCGTGCTCGAGGTCGCGCTGCTGCTGATC
GTCACGATCGTGATCGCGCTCGTGCTCGGCATCGCGATCGTCAGCATCGACTATTCGATCCTGCGCGTCGCGTGCATGGT
CGTGATGTCGGTCGGGCTGCTGTACCTGACGTCGGCCAGCAAGCTGCGCCCGGTCGGCGCGATTCTCGCGATGATCGTCG
GCTTCGGGCTCGACGAGCTCGGCCTCGCGCCGTTCGGCGAAGCGGCGACGCGCGCGCTGCTCTATATCTGGCTGACGGTC
GCGATTCCGGTCGGCGTCGCGATCGTCGTCAATCTGCTGATCGCACCGTCGCCGCGCAAGCTCGCGCTCGCGCAGCTCGC
CAAGCGGCTGCGGCTCGCCGCGCGGCGACTGCGCGGCGACGACGACGCGCGCGCCGGTTTCGACGCCAGCCTGCGCGAGG
GCGACAAGCAACTGCTGACCTGGCTCAAGCTGTCGAAGCTCGAAGGCTCGTCGTCCGCCGCCGACATCCTCGCGCTGCGG
CAGGCCGTTGCATCGAGCACCGCGCTGCTCGTCGCGGTCGCGCTCGCCGATCGCGAAGCGGATGCGCGGCTACCCGACAC
GTTCGCGACACCGATCGCCGCCACGCTCGACGACATGGCCGCCATCCTCGAACGCGGCGGCTATCCCGTCGACATCACGC
TCGCGCTGCCGCCGGCGGACACGCTGCCGCCGCTCGCGCGCGTCGCCGCAGCGGACCTGCACGCGGCGATCACGCGCTTC
GCCGAGCCTGATGCAACTGCCGGCACGCCACCGGTCGATACCGCAAAACCGACCGCCCCGTCCGACGAACCGTCCGCTGC
GCCGACGCCGCAACCCGCGCCCTCCGCATCGCCACGCGGCGGCTTCTTCCTGCCCGACGCGCGCACCAATCCGGACCACA
TCCGCTACGCGCTGAAAACGACGGCCGCGGCGATGTTCTGCTACCTGCTGTACTCGCAGCTCGACTGGTCGGGCATCCAT
ACCTGCTTCATCACCTGCTACATCGTGTCGCTCGGCTCGACGGCCGAAACGGTCGAGAAGCTGACGCTGCGGATCGCCGG
CTGCATCGTCGGCGCGCTGCTCGGCACTGCCGCGCTCGTGTTCGTCGTGCCGTCGCTGACGTCGATCGGTCAACTGATGA
TGCTCGTGTTCGTCGGCGCGTGGCTGTCCGCGTGGGTCTCGTTCGGCTCGCCGCGCATCGCCTACGCAGGCTTCCAGATC
GCGTTCGCGTTCTTCCTCTGCGTGATCCAGGGCGCCGGGCCGGGCTTCGATCTGACGATCGCGCGCGACCGCACGATCGG
CATCCTGCTCGGCAACGTCGTCGTGTATCTCGTGTTCACGCGCATCTGGCCCGTCAGCATCGGCAAGCAGATCGACGTCG
CGCTCGCGGCGCTGCGCGAGCAGTGGCGACGGCTCGTGCAGGTCGCGCAGCCGGCGGAGCGGCGCACACTCGCGGCCGAG
GCATTCGCGCGCCACGGCGCGATCGCGCAGGAACTCGGCCTCGTTCACTACGAACCGTCGTGGGTGCGACCGAGCGCGGC
CTGGCTCGATTCGCGCCGACGCGTGCTGGCCGAGCTCGGCGCGCTCGAAGGTCCGCTGTTCCTGCTCGCCGAGCGTGCGC
CGGGCGACGCGGCGATCGGCACGCGGCTCGCGCGCGTGGCCGAATTGCGCGACGACGAAGCGACGCCGGCCGCACACGAT
GCGCGGGAAGAAGCAAGCCCGACGGCGGCCGACGCGCCTTCGTCGTCGCAACCGGCCGCGCCGCCCGTGCCGAACGCCGA
GCGTGCGCGTGCGCCTGCGCCTGGGCTTGGGCCGCACCCCGCCGGGCCGCCCGACCCTGCGCGCGACGCACTGCTGAACC
TCATCGACGCGCGACTCGCCGCCATCGCCGACGCCGCGCGCCAAGCCACTTCGAAGGAGTCTGCCGCTCATGCGCCGACC
TGA

Upstream 100 bases:

>100_bases
TGGGTGCATGTCGCGCAGCGCTTCCCCGTGCGCGTGAAGCTCGACGAACCCGACGCGGGGCTCGTGCGCGTCGGCGCCAG
CGCGATCGTCGAGGTCCGGC

Downstream 100 bases:

>100_bases
ACCGCCGGCCGCGTCGATCGTCGCAGCCGCCCTCGCAAGCGCCGTCGCGCTGGCCGGCTGCGCGACCTCGTCGATCGATC
TCGCGCCCAACGCATCGGAC

Product: putative fusaric acid resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MAQPAAEVRSPGLREVLRLLAPFPGRTAIAVRVALICTLTVLVTSAYGTPEAALSAYVVFFMIRADRVTSIVLEVALLLI
VTIVIALVLGIAIVSIDYSILRVACMVVMSVGLLYLTSASKLRPVGAILAMIVGFGLDELGLAPFGEAATRALLYIWLTV
AIPVGVAIVVNLLIAPSPRKLALAQLAKRLRLAARRLRGDDDARAGFDASLREGDKQLLTWLKLSKLEGSSSAADILALR
QAVASSTALLVAVALADREADARLPDTFATPIAATLDDMAAILERGGYPVDITLALPPADTLPPLARVAAADLHAAITRF
AEPDATAGTPPVDTAKPTAPSDEPSAAPTPQPAPSASPRGGFFLPDARTNPDHIRYALKTTAAAMFCYLLYSQLDWSGIH
TCFITCYIVSLGSTAETVEKLTLRIAGCIVGALLGTAALVFVVPSLTSIGQLMMLVFVGAWLSAWVSFGSPRIAYAGFQI
AFAFFLCVIQGAGPGFDLTIARDRTIGILLGNVVVYLVFTRIWPVSIGKQIDVALAALREQWRRLVQVAQPAERRTLAAE
AFARHGAIAQELGLVHYEPSWVRPSAAWLDSRRRVLAELGALEGPLFLLAERAPGDAAIGTRLARVAELRDDEATPAAHD
AREEASPTAADAPSSSQPAAPPVPNAERARAPAPGLGPHPAGPPDPARDALLNLIDARLAAIADAARQATSKESAAHAPT

Sequences:

>Translated_720_residues
MAQPAAEVRSPGLREVLRLLAPFPGRTAIAVRVALICTLTVLVTSAYGTPEAALSAYVVFFMIRADRVTSIVLEVALLLI
VTIVIALVLGIAIVSIDYSILRVACMVVMSVGLLYLTSASKLRPVGAILAMIVGFGLDELGLAPFGEAATRALLYIWLTV
AIPVGVAIVVNLLIAPSPRKLALAQLAKRLRLAARRLRGDDDARAGFDASLREGDKQLLTWLKLSKLEGSSSAADILALR
QAVASSTALLVAVALADREADARLPDTFATPIAATLDDMAAILERGGYPVDITLALPPADTLPPLARVAAADLHAAITRF
AEPDATAGTPPVDTAKPTAPSDEPSAAPTPQPAPSASPRGGFFLPDARTNPDHIRYALKTTAAAMFCYLLYSQLDWSGIH
TCFITCYIVSLGSTAETVEKLTLRIAGCIVGALLGTAALVFVVPSLTSIGQLMMLVFVGAWLSAWVSFGSPRIAYAGFQI
AFAFFLCVIQGAGPGFDLTIARDRTIGILLGNVVVYLVFTRIWPVSIGKQIDVALAALREQWRRLVQVAQPAERRTLAAE
AFARHGAIAQELGLVHYEPSWVRPSAAWLDSRRRVLAELGALEGPLFLLAERAPGDAAIGTRLARVAELRDDEATPAAHD
AREEASPTAADAPSSSQPAAPPVPNAERARAPAPGLGPHPAGPPDPARDALLNLIDARLAAIADAARQATSKESAAHAPT
>Mature_719_residues
AQPAAEVRSPGLREVLRLLAPFPGRTAIAVRVALICTLTVLVTSAYGTPEAALSAYVVFFMIRADRVTSIVLEVALLLIV
TIVIALVLGIAIVSIDYSILRVACMVVMSVGLLYLTSASKLRPVGAILAMIVGFGLDELGLAPFGEAATRALLYIWLTVA
IPVGVAIVVNLLIAPSPRKLALAQLAKRLRLAARRLRGDDDARAGFDASLREGDKQLLTWLKLSKLEGSSSAADILALRQ
AVASSTALLVAVALADREADARLPDTFATPIAATLDDMAAILERGGYPVDITLALPPADTLPPLARVAAADLHAAITRFA
EPDATAGTPPVDTAKPTAPSDEPSAAPTPQPAPSASPRGGFFLPDARTNPDHIRYALKTTAAAMFCYLLYSQLDWSGIHT
CFITCYIVSLGSTAETVEKLTLRIAGCIVGALLGTAALVFVVPSLTSIGQLMMLVFVGAWLSAWVSFGSPRIAYAGFQIA
FAFFLCVIQGAGPGFDLTIARDRTIGILLGNVVVYLVFTRIWPVSIGKQIDVALAALREQWRRLVQVAQPAERRTLAAEA
FARHGAIAQELGLVHYEPSWVRPSAAWLDSRRRVLAELGALEGPLFLLAERAPGDAAIGTRLARVAELRDDEATPAAHDA
REEASPTAADAPSSSQPAAPPVPNAERARAPAPGLGPHPAGPPDPARDALLNLIDARLAAIADAARQATSKESAAHAPT

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MdtO family [H]

Homologues:

Organism=Escherichia coli, GI87082367, Length=539, Percent_Identity=26.530612244898, Blast_Score=145, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 75778; Mature: 75647

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPAAEVRSPGLREVLRLLAPFPGRTAIAVRVALICTLTVLVTSAYGTPEAALSAYVVF
CCCCCHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FMIRADRVTSIVLEVALLLIVTIVIALVLGIAIVSIDYSILRVACMVVMSVGLLYLTSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KLRPVGAILAMIVGFGLDELGLAPFGEAATRALLYIWLTVAIPVGVAIVVNLLIAPSPRK
HHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LALAQLAKRLRLAARRLRGDDDARAGFDASLREGDKQLLTWLKLSKLEGSSSAADILALR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QAVASSTALLVAVALADREADARLPDTFATPIAATLDDMAAILERGGYPVDITLALPPAD
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
TLPPLARVAAADLHAAITRFAEPDATAGTPPVDTAKPTAPSDEPSAAPTPQPAPSASPRG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFFLPDARTNPDHIRYALKTTAAAMFCYLLYSQLDWSGIHTCFITCYIVSLGSTAETVEK
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHH
LTLRIAGCIVGALLGTAALVFVVPSLTSIGQLMMLVFVGAWLSAWVSFGSPRIAYAGFQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHH
AFAFFLCVIQGAGPGFDLTIARDRTIGILLGNVVVYLVFTRIWPVSIGKQIDVALAALRE
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QWRRLVQVAQPAERRTLAAEAFARHGAIAQELGLVHYEPSWVRPSAAWLDSRRRVLAELG
HHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHC
ALEGPLFLLAERAPGDAAIGTRLARVAELRDDEATPAAHDAREEASPTAADAPSSSQPAA
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
PPVPNAERARAPAPGLGPHPAGPPDPARDALLNLIDARLAAIADAARQATSKESAAHAPT
CCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQPAAEVRSPGLREVLRLLAPFPGRTAIAVRVALICTLTVLVTSAYGTPEAALSAYVVF
CCCCHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FMIRADRVTSIVLEVALLLIVTIVIALVLGIAIVSIDYSILRVACMVVMSVGLLYLTSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KLRPVGAILAMIVGFGLDELGLAPFGEAATRALLYIWLTVAIPVGVAIVVNLLIAPSPRK
HHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LALAQLAKRLRLAARRLRGDDDARAGFDASLREGDKQLLTWLKLSKLEGSSSAADILALR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QAVASSTALLVAVALADREADARLPDTFATPIAATLDDMAAILERGGYPVDITLALPPAD
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
TLPPLARVAAADLHAAITRFAEPDATAGTPPVDTAKPTAPSDEPSAAPTPQPAPSASPRG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFFLPDARTNPDHIRYALKTTAAAMFCYLLYSQLDWSGIHTCFITCYIVSLGSTAETVEK
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHH
LTLRIAGCIVGALLGTAALVFVVPSLTSIGQLMMLVFVGAWLSAWVSFGSPRIAYAGFQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHH
AFAFFLCVIQGAGPGFDLTIARDRTIGILLGNVVVYLVFTRIWPVSIGKQIDVALAALRE
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QWRRLVQVAQPAERRTLAAEAFARHGAIAQELGLVHYEPSWVRPSAAWLDSRRRVLAELG
HHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHC
ALEGPLFLLAERAPGDAAIGTRLARVAELRDDEATPAAHDAREEASPTAADAPSSSQPAA
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
PPVPNAERARAPAPGLGPHPAGPPDPARDALLNLIDARLAAIADAARQATSKESAAHAPT
CCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]