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The map label for this gene is ephD [H]

Identifier: 189353248

GI number: 189353248

Start: 1482887

End: 1483798

Strand: Direct

Name: ephD [H]

Synonym: BMULJ_04488

Alternate gene names: 189353248

Gene position: 1482887-1483798 (Clockwise)

Preceding gene: 189353247

Following gene: 189353250

Centisome position: 59.96

GC content: 69.3

Gene sequence:

>912_bases
ATGGCGCGCGATCGCGACATGCTGACCGTCCGCTCCGGCGACGTGAAGCTCGCCGTCTACGTCAGCGGCCCGCGTCGCGC
GCCGCCGCTGATTCTCGTGCACGGCTATCCCGATTCGGCCGCCGTGTGGGCGCCGATTCGCGCACGGCTTGCCGGGCGCT
ATCGCGTGATCGCCTACGACGTGCGCGGCGCGGGGGCGTCCGATGCACCGCGACACCGCGCCGACTACGCGCTCGCGCGC
CTGGCGGACGACCTGAAGGCGGTTGCCGATGCGACCTGCGGCGACCGTCCGTTTCATCTCGTCGGCCACGACTGGGGGTC
GATCCAGTGCTGGGAGGCTGTGACCGACCCTGCGTTTCGCGGGCGGATCGCGTCGTATACGTCGATCTCGGGCCCGTGCC
TCGATCACGTGTTCCGCGCGAGGATGCGGCTCAAGCAGAGCCTGAAATCGTGGTACATCGCGTTCTTTCATCTGCCGATC
GTGCCGTCGCTGGTCTGGCGGCTCGGCGGCGCCGCGCTGTGGCCGCGCTGGTTGCAGCTGACCGAACGCGTGCGCGTCGA
GCGCGATCCGTCGCAATTGAAGAATGCGCTGAACGGGTTGCAGTTGTACCGCGCGAATTTCATCGCGCGCGCAAGCAAGC
CGCGCGAGCGGTATGCGCAGGCGCCGGTGCAGATTCTCGTGCCGGTGCGCGACCGCTACGTGACGCCCGAGATGACGATC
GATCTCGATCGCTGGCTCGGCGAGCATGTGCGCGAGGAGCTCGACGGGGCCCACTGGATCGTGCTGCGCGATCCCGACCT
GATCGCGTCGCGGATCGACCGCTTCGCGTCCGCACACGAAGGCACGACCGCGCCGTCGGCCGCGGCCGCCGCTCAGGCGG
GCATCGGCAGACGCCTGAACAGCGTCTCGTAG

Upstream 100 bases:

>100_bases
GACACGCTGCTCGCGAACATCGACGCGACCAACGCGCGCTATGCGGCGCAGGCCGCGCCGCGTCGCGTGCCGCTGCATCC
CGTCGCGCAGGCATGATGCG

Downstream 100 bases:

>100_bases
TCGATCACGAGGCCATCGTCGTCGACGTCCATCTCGGCCGTGAAGTTGCGGAAGATCCCTTCATAGCGGTAGCGCCGGCC
CGGCTCGAGGCAGGTGTACG

Product: haloacetate dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MARDRDMLTVRSGDVKLAVYVSGPRRAPPLILVHGYPDSAAVWAPIRARLAGRYRVIAYDVRGAGASDAPRHRADYALAR
LADDLKAVADATCGDRPFHLVGHDWGSIQCWEAVTDPAFRGRIASYTSISGPCLDHVFRARMRLKQSLKSWYIAFFHLPI
VPSLVWRLGGAALWPRWLQLTERVRVERDPSQLKNALNGLQLYRANFIARASKPRERYAQAPVQILVPVRDRYVTPEMTI
DLDRWLGEHVREELDGAHWIVLRDPDLIASRIDRFASAHEGTTAPSAAAAAQAGIGRRLNSVS

Sequences:

>Translated_303_residues
MARDRDMLTVRSGDVKLAVYVSGPRRAPPLILVHGYPDSAAVWAPIRARLAGRYRVIAYDVRGAGASDAPRHRADYALAR
LADDLKAVADATCGDRPFHLVGHDWGSIQCWEAVTDPAFRGRIASYTSISGPCLDHVFRARMRLKQSLKSWYIAFFHLPI
VPSLVWRLGGAALWPRWLQLTERVRVERDPSQLKNALNGLQLYRANFIARASKPRERYAQAPVQILVPVRDRYVTPEMTI
DLDRWLGEHVREELDGAHWIVLRDPDLIASRIDRFASAHEGTTAPSAAAAAQAGIGRRLNSVS
>Mature_302_residues
ARDRDMLTVRSGDVKLAVYVSGPRRAPPLILVHGYPDSAAVWAPIRARLAGRYRVIAYDVRGAGASDAPRHRADYALARL
ADDLKAVADATCGDRPFHLVGHDWGSIQCWEAVTDPAFRGRIASYTSISGPCLDHVFRARMRLKQSLKSWYIAFFHLPIV
PSLVWRLGGAALWPRWLQLTERVRVERDPSQLKNALNGLQLYRANFIARASKPRERYAQAPVQILVPVRDRYVTPEMTID
LDRWLGEHVREELDGAHWIVLRDPDLIASRIDRFASAHEGTTAPSAAAAAQAGIGRRLNSVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=287, Percent_Identity=25.0871080139373, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI218777840, Length=161, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI13376164, Length=161, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17554012, Length=293, Percent_Identity=22.8668941979522, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562298, Length=159, Percent_Identity=27.6729559748428, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 33870; Mature: 33739

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDRDMLTVRSGDVKLAVYVSGPRRAPPLILVHGYPDSAAVWAPIRARLAGRYRVIAYD
CCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
VRGAGASDAPRHRADYALARLADDLKAVADATCGDRPFHLVGHDWGSIQCWEAVTDPAFR
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEHHHHCCHHHH
GRIASYTSISGPCLDHVFRARMRLKQSLKSWYIAFFHLPIVPSLVWRLGGAALWPRWLQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TERVRVERDPSQLKNALNGLQLYRANFIARASKPRERYAQAPVQILVPVRDRYVTPEMTI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCCCCCCCCEE
DLDRWLGEHVREELDGAHWIVLRDPDLIASRIDRFASAHEGTTAPSAAAAAQAGIGRRLN
EHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
SVS
CCC
>Mature Secondary Structure 
ARDRDMLTVRSGDVKLAVYVSGPRRAPPLILVHGYPDSAAVWAPIRARLAGRYRVIAYD
CCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
VRGAGASDAPRHRADYALARLADDLKAVADATCGDRPFHLVGHDWGSIQCWEAVTDPAFR
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEHHHHCCHHHH
GRIASYTSISGPCLDHVFRARMRLKQSLKSWYIAFFHLPIVPSLVWRLGGAALWPRWLQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TERVRVERDPSQLKNALNGLQLYRANFIARASKPRERYAQAPVQILVPVRDRYVTPEMTI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCCCCCCCCEE
DLDRWLGEHVREELDGAHWIVLRDPDLIASRIDRFASAHEGTTAPSAAAAAQAGIGRRLN
EHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
SVS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]