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The map label for this gene is nahR [H]

Identifier: 189353234

GI number: 189353234

Start: 1464572

End: 1465516

Strand: Direct

Name: nahR [H]

Synonym: BMULJ_04472

Alternate gene names: 189353234

Gene position: 1464572-1465516 (Clockwise)

Preceding gene: 189353232

Following gene: 189353235

Centisome position: 59.22

GC content: 67.2

Gene sequence:

>945_bases
ATGGAACTGAGCGACCTCGACCTCAACCTGCTGTTGTTGTTCCAGCGGCTGATGCAGGAACGGCGCGTGTCGACCGTCGC
CGAGCAGATGAACATGAGTCAGCCGGGGGTCAGCAACGCGCTTGCGAAGCTGCGTCGACGGCTCGGCGATCCGCTCTTCG
TGCGCGCGCCGGGCGGTGTCGTGCCGACGCCGTTCGCGCTGCGTCTGGCCGAACCCGTTTCGCACGCGCTCGCGACGCTG
CACGCCGCGCTCAATCCCGAGACGGGCTTCGACCCGCAGCATGCCGTGCGCACGATCACGATCGGCATGACCGATATCGG
CGAAGTCGTGTTCCTGCCCGCGTTGCTGGAACGCCTCGCGCAGACGGCGCCCGGTATCGTCCTGAACACCGTGCGGAACA
CGAGCGTGAACCTGAGCGACGAAATGGCCGAGGGCCGCGTCGACCTCGCGATCGGGCTGCTGCCGCAGCTACAGGGCGGT
TTCTATCAGCGCCGGCTGTTCGATCAACGGTATGTGTGCCTGTTTCGGCGCGGGCATCCGCTCGAGGCCGCGCCGCTCAC
GCTCGACGCGTGGCGCGACGCCGGCCATCTGGTCGTGGTGTCGGCCGGGACCGGCCACGGGCAAGTGGACGAATGGCTGA
AGCGGCGACGCGTGACGCGCAACGTGCGGCTGACGGTGCCGCATTTCATGAGCGTCGGCTATATCCTGCAACGCACCGAC
CTGATCGCGACGGTGCCGGAGCATCTCGCGCTGCAGCTCGCGACGCCGTTTTCGCTAAGCTGGCGTGCGCTGCCGGTGAC
GCTGCCCGGCGCACCGATTCATATGCTGTGGCACGCGCGCATGAATCAGGACGAGGGCAACCGCTGGCTGCGGGACGTCG
TGGTCGAATTGTTCGCAGAGGCCGGCGTGCGGCAGCGGAAATCGGGACCGGCGCGAAAGAAATAG

Upstream 100 bases:

>100_bases
GCGTCGTACCGGTATTGTCGGGAGCGGGGTTTCATCCCACAATAAAATGCAAGGAATCCGCTTCATCACAGAACGAAATA
ATCGGGAGCCACGCCAAACC

Downstream 100 bases:

>100_bases
GCGCGTGTACGATGTCGCGTCATGGGCGACGGCATCTTGCGACGGCATCTTGCGACGACATCGCGCGTGCGTCCGCGCCA
TCCCTCTTCAACCAGCAGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MELSDLDLNLLLLFQRLMQERRVSTVAEQMNMSQPGVSNALAKLRRRLGDPLFVRAPGGVVPTPFALRLAEPVSHALATL
HAALNPETGFDPQHAVRTITIGMTDIGEVVFLPALLERLAQTAPGIVLNTVRNTSVNLSDEMAEGRVDLAIGLLPQLQGG
FYQRRLFDQRYVCLFRRGHPLEAAPLTLDAWRDAGHLVVVSAGTGHGQVDEWLKRRRVTRNVRLTVPHFMSVGYILQRTD
LIATVPEHLALQLATPFSLSWRALPVTLPGAPIHMLWHARMNQDEGNRWLRDVVVELFAEAGVRQRKSGPARKK

Sequences:

>Translated_314_residues
MELSDLDLNLLLLFQRLMQERRVSTVAEQMNMSQPGVSNALAKLRRRLGDPLFVRAPGGVVPTPFALRLAEPVSHALATL
HAALNPETGFDPQHAVRTITIGMTDIGEVVFLPALLERLAQTAPGIVLNTVRNTSVNLSDEMAEGRVDLAIGLLPQLQGG
FYQRRLFDQRYVCLFRRGHPLEAAPLTLDAWRDAGHLVVVSAGTGHGQVDEWLKRRRVTRNVRLTVPHFMSVGYILQRTD
LIATVPEHLALQLATPFSLSWRALPVTLPGAPIHMLWHARMNQDEGNRWLRDVVVELFAEAGVRQRKSGPARKK
>Mature_314_residues
MELSDLDLNLLLLFQRLMQERRVSTVAEQMNMSQPGVSNALAKLRRRLGDPLFVRAPGGVVPTPFALRLAEPVSHALATL
HAALNPETGFDPQHAVRTITIGMTDIGEVVFLPALLERLAQTAPGIVLNTVRNTSVNLSDEMAEGRVDLAIGLLPQLQGG
FYQRRLFDQRYVCLFRRGHPLEAAPLTLDAWRDAGHLVVVSAGTGHGQVDEWLKRRRVTRNVRLTVPHFMSVGYILQRTD
LIATVPEHLALQLATPFSLSWRALPVTLPGAPIHMLWHARMNQDEGNRWLRDVVVELFAEAGVRQRKSGPARKK

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=297, Percent_Identity=25.9259259259259, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87081766, Length=260, Percent_Identity=25, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790147, Length=306, Percent_Identity=24.5098039215686, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787601, Length=224, Percent_Identity=24.1071428571429, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34987; Mature: 34987

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSDLDLNLLLLFQRLMQERRVSTVAEQMNMSQPGVSNALAKLRRRLGDPLFVRAPGGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
VPTPFALRLAEPVSHALATLHAALNPETGFDPQHAVRTITIGMTDIGEVVFLPALLERLA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCHHHHHHHHHHHHHHHHH
QTAPGIVLNTVRNTSVNLSDEMAEGRVDLAIGLLPQLQGGFYQRRLFDQRYVCLFRRGHP
HHCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCC
LEAAPLTLDAWRDAGHLVVVSAGTGHGQVDEWLKRRRVTRNVRLTVPHFMSVGYILQRTD
CCCCCEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHH
LIATVPEHLALQLATPFSLSWRALPVTLPGAPIHMLWHARMNQDEGNRWLRDVVVELFAE
HHHHCHHHHEEEECCCCCCCEEEEEEECCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHH
AGVRQRKSGPARKK
HCHHHHCCCCCCCC
>Mature Secondary Structure
MELSDLDLNLLLLFQRLMQERRVSTVAEQMNMSQPGVSNALAKLRRRLGDPLFVRAPGGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
VPTPFALRLAEPVSHALATLHAALNPETGFDPQHAVRTITIGMTDIGEVVFLPALLERLA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCHHHHHHHHHHHHHHHHH
QTAPGIVLNTVRNTSVNLSDEMAEGRVDLAIGLLPQLQGGFYQRRLFDQRYVCLFRRGHP
HHCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCC
LEAAPLTLDAWRDAGHLVVVSAGTGHGQVDEWLKRRRVTRNVRLTVPHFMSVGYILQRTD
CCCCCEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHH
LIATVPEHLALQLATPFSLSWRALPVTLPGAPIHMLWHARMNQDEGNRWLRDVVVELFAE
HHHHCHHHHEEEECCCCCCCEEEEEEECCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHH
AGVRQRKSGPARKK
HCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]