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The map label for this gene is yccK [H]

Identifier: 189353225

GI number: 189353225

Start: 1453881

End: 1454894

Strand: Reverse

Name: yccK [H]

Synonym: BMULJ_04463

Alternate gene names: 189353225

Gene position: 1454894-1453881 (Counterclockwise)

Preceding gene: 189353227

Following gene: 189353224

Centisome position: 58.83

GC content: 69.23

Gene sequence:

>1014_bases
ATGAAAACACGTCAATTGGGCCGCACGCGCCCGCAGGTATCGGCGATCGGGCTCGGCTGCATGGGCATGTCGGATCTCTA
CGGCCCGGCCGACCGCGACGAAAGCATCGCGACGCTGCACGCCGCGCTCGATCACGGGATCACGCTGCTCGACACCGGCG
ATTTCTACGGGATGGGCGACAACGAAATGCTGATCCGCGATGCGCTGCGCGGCCGCACGCGCGAGCAGGTGCTGATCAGC
GTGAAGTTCGGCGCGCTGCGCGATCCGGCCGGCGGCTTCGCCGGCTACGATGCGCGGCCGGTCGCGATCCGCAACTTCGT
CGCCTATACGCTGAAGCGGCTCGGCACCGACTACATCGATCTCTACCGGCCGGCGCGCGTCGATCCGGCGGTGCCGATCG
AGGAGACGGTCGGCGCGATCGCCGATCTCGTGAAGGCCGGCTACGTGCGCCATATCGGCTTGTCGGAGGTCGGCGCCGAC
ACGCTTCGCCGCGCGGCGGCCGTCGCGCCGATCGCCGATCTGCAGATCGAATATTCGCTGCTGTCGCGCGGGATCGAGGA
CGCGATCCTGCCGACGTGCCGCGCGCTCGGCATCGGCGTGACCGCGTACGGCGTGCTGTCGCGCGGCCTGCTGGGCGGCG
GCTGGAATAGGGCGCAGCCGCGCGAGCGCGATTTCCGTGCAGCGAGCCCGCGCTTCCAGGGCGCGAATCTCGAACACAAT
CTCGCGCTCGTCGACGCGTTGCGCACGATTGCCGACGAAAAGGACAGCAACCCCGCGCAGATCGCGATCGCCTGGGCGCT
GTCGCGCGGCGACGACATCGTGCCGTTGATCGGCGCGCGCAAGCGCACGCAGCTCCGCGATGCGTTGCAAGCCTCGTCGA
TGCAACTAACGGTCGATGACCTCGCGCGTATCGAAGCGGCGGTTCCCGCCGGGGCCGCGGCGGGCGAACGCTATCCGGCC
GCACAGATGGCGCACCTCGATAGCGAGCAGGGACGGGGGGCTCACGAGGGCTGA

Upstream 100 bases:

>100_bases
GTTAATCAGCGTCGAATGATTTGGTTGCGCGTTTCGCGTTTATCGCGCGCGGCGTTCCGTCCAGAATGCGGTCCATCGGT
CACCACGCGAAGGAACGCAC

Downstream 100 bases:

>100_bases
GCGCTGGGCCGGCGAGCTGCCCCGCGCGCCGGACCCTAGCCGGACTCAGGCAAAACCAGATGGTGGACGGCGCGCGGGCG
GTGCACCATCGGCACCGTAG

Product: pyridoxine 4-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKTRQLGRTRPQVSAIGLGCMGMSDLYGPADRDESIATLHAALDHGITLLDTGDFYGMGDNEMLIRDALRGRTREQVLIS
VKFGALRDPAGGFAGYDARPVAIRNFVAYTLKRLGTDYIDLYRPARVDPAVPIEETVGAIADLVKAGYVRHIGLSEVGAD
TLRRAAAVAPIADLQIEYSLLSRGIEDAILPTCRALGIGVTAYGVLSRGLLGGGWNRAQPRERDFRAASPRFQGANLEHN
LALVDALRTIADEKDSNPAQIAIAWALSRGDDIVPLIGARKRTQLRDALQASSMQLTVDDLARIEAAVPAGAAAGERYPA
AQMAHLDSEQGRGAHEG

Sequences:

>Translated_337_residues
MKTRQLGRTRPQVSAIGLGCMGMSDLYGPADRDESIATLHAALDHGITLLDTGDFYGMGDNEMLIRDALRGRTREQVLIS
VKFGALRDPAGGFAGYDARPVAIRNFVAYTLKRLGTDYIDLYRPARVDPAVPIEETVGAIADLVKAGYVRHIGLSEVGAD
TLRRAAAVAPIADLQIEYSLLSRGIEDAILPTCRALGIGVTAYGVLSRGLLGGGWNRAQPRERDFRAASPRFQGANLEHN
LALVDALRTIADEKDSNPAQIAIAWALSRGDDIVPLIGARKRTQLRDALQASSMQLTVDDLARIEAAVPAGAAAGERYPA
AQMAHLDSEQGRGAHEG
>Mature_337_residues
MKTRQLGRTRPQVSAIGLGCMGMSDLYGPADRDESIATLHAALDHGITLLDTGDFYGMGDNEMLIRDALRGRTREQVLIS
VKFGALRDPAGGFAGYDARPVAIRNFVAYTLKRLGTDYIDLYRPARVDPAVPIEETVGAIADLVKAGYVRHIGLSEVGAD
TLRRAAAVAPIADLQIEYSLLSRGIEDAILPTCRALGIGVTAYGVLSRGLLGGGWNRAQPRERDFRAASPRFQGANLEHN
LALVDALRTIADEKDSNPAQIAIAWALSRGDDIVPLIGARKRTQLRDALQASSMQLTVDDLARIEAAVPAGAAAGERYPA
AQMAHLDSEQGRGAHEG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=26.537216828479, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI4504825, Length=306, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=28.1345565749235, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI27436964, Length=309, Percent_Identity=25.2427184466019, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=24.9190938511327, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=24.9190938511327, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI223718702, Length=242, Percent_Identity=29.7520661157025, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=32.3899371069182, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=30.6501547987616, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=27.4390243902439, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=29.5977011494253, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788081, Length=300, Percent_Identity=27.6666666666667, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787674, Length=315, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=25.8823529411765, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=340, Percent_Identity=27.6470588235294, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=24.8344370860927, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=261, Percent_Identity=27.2030651340996, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325384, Length=336, Percent_Identity=25.297619047619, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=337, Percent_Identity=24.3323442136499, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646159, Length=238, Percent_Identity=31.0924369747899, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646155, Length=159, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36091; Mature: 36091

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRQLGRTRPQVSAIGLGCMGMSDLYGPADRDESIATLHAALDHGITLLDTGDFYGMGD
CCCCCCCCCCCCHHHHEECCCCHHHHCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCC
NEMLIRDALRGRTREQVLISVKFGALRDPAGGFAGYDARPVAIRNFVAYTLKRLGTDYID
CHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
LYRPARVDPAVPIEETVGAIADLVKAGYVRHIGLSEVGADTLRRAAAVAPIADLQIEYSL
HCCCCCCCCCCCHHHHHHHHHHHHHHCHHHCCCHHHHCHHHHHHHHHHCCHHHHEEEHHH
LSRGIEDAILPTCRALGIGVTAYGVLSRGLLGGGWNRAQPRERDFRAASPRFQGANLEHN
HHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
LALVDALRTIADEKDSNPAQIAIAWALSRGDDIVPLIGARKRTQLRDALQASSMQLTVDD
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHCCCEEEHHH
LARIEAAVPAGAAAGERYPAAQMAHLDSEQGRGAHEG
HHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKTRQLGRTRPQVSAIGLGCMGMSDLYGPADRDESIATLHAALDHGITLLDTGDFYGMGD
CCCCCCCCCCCCHHHHEECCCCHHHHCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCC
NEMLIRDALRGRTREQVLISVKFGALRDPAGGFAGYDARPVAIRNFVAYTLKRLGTDYID
CHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
LYRPARVDPAVPIEETVGAIADLVKAGYVRHIGLSEVGADTLRRAAAVAPIADLQIEYSL
HCCCCCCCCCCCHHHHHHHHHHHHHHCHHHCCCHHHHCHHHHHHHHHHCCHHHHEEEHHH
LSRGIEDAILPTCRALGIGVTAYGVLSRGLLGGGWNRAQPRERDFRAASPRFQGANLEHN
HHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
LALVDALRTIADEKDSNPAQIAIAWALSRGDDIVPLIGARKRTQLRDALQASSMQLTVDD
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHCCCEEEHHH
LARIEAAVPAGAAAGERYPAAQMAHLDSEQGRGAHEG
HHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]