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The map label for this gene is uxuR [H]

Identifier: 189353114

GI number: 189353114

Start: 1298155

End: 1298877

Strand: Reverse

Name: uxuR [H]

Synonym: BMULJ_04350

Alternate gene names: 189353114

Gene position: 1298877-1298155 (Counterclockwise)

Preceding gene: 189353118

Following gene: 189353113

Centisome position: 52.52

GC content: 67.22

Gene sequence:

>723_bases
ATGACCGATCTTTCCAGCCTGCCCACTTCCCGCGATACCGATGCCGCCGACCGTTCCTATATCGGTCTCGCACGGCAGAT
TCACGCGATGATCGCGTCCGGCGCGCTCGAAGCCGGCGCGCGGCTGCCGTCGGAGCGCAGCCTGGCCGACCAGTTCGGCG
TGAGCCGCACGCAGGTGCGCGAGGCGATCATTGCGCTCGAGGTGCAGGGCATCGTCGAGGTGCGCGTCGGGTCGGGGATC
TACGTGTCGGCCGCGGATGCCGCGCGGCCCGTTTCGTTCGAGCTGCCGCGCGGACCGGGCCCGATCGAGACGCTGCGCGC
GCGCGGGCTGATCGAGGCGGAAGTCGCGGCGCTCGCGGCAACCGAGCGCAAGGACGCCGATCTCGACCGGCTGTTCTTCT
CGTTGACGACGATGCGCGAGCAGATGGGCGACAAGGCCGCCTACCACGCGGCCGACCGCCAGTTTCATCTGCGCATTGCC
GAATCGACGGGCAATACGGTGCTGCTGCATATGGTCACGGCCATGTGGGACTGTGCGCGCAGCGATCCGCTGTGGGACAA
GATCGAGCAGCACTTTCATTCGCCGGCATTGCGCGAGGCGTCGCAGGAAGATCACCAGCGAATCTTCTCGGCGATCATGG
CGCGCGATGCAGACGGCGCACGCGAGGCGATGCGTGCACATCTGTCGCGCGTGATCGCGGAATTTACGCAGGCGTGGCGT
TAG

Upstream 100 bases:

>100_bases
ATGATGAGAACCGACGCGAGTAGGGCGGCAGCGGAAATTGGTGTACCATTTTCGCGACCCGGTGCCGCGACGATGCCGGC
CCGCCCGTGACGAGCTTTCG

Downstream 100 bases:

>100_bases
CGCGGAGTCGACGTCGCGTGGGCGCGAGACGATGTGCCGCTGTCGGACCTCGCCGCCCTCGATCGGCGATCGGGCGTGCG
CCCGCGACGTCGCGCACGAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTDLSSLPTSRDTDAADRSYIGLARQIHAMIASGALEAGARLPSERSLADQFGVSRTQVREAIIALEVQGIVEVRVGSGI
YVSAADAARPVSFELPRGPGPIETLRARGLIEAEVAALAATERKDADLDRLFFSLTTMREQMGDKAAYHAADRQFHLRIA
ESTGNTVLLHMVTAMWDCARSDPLWDKIEQHFHSPALREASQEDHQRIFSAIMARDADGAREAMRAHLSRVIAEFTQAWR

Sequences:

>Translated_240_residues
MTDLSSLPTSRDTDAADRSYIGLARQIHAMIASGALEAGARLPSERSLADQFGVSRTQVREAIIALEVQGIVEVRVGSGI
YVSAADAARPVSFELPRGPGPIETLRARGLIEAEVAALAATERKDADLDRLFFSLTTMREQMGDKAAYHAADRQFHLRIA
ESTGNTVLLHMVTAMWDCARSDPLWDKIEQHFHSPALREASQEDHQRIFSAIMARDADGAREAMRAHLSRVIAEFTQAWR
>Mature_239_residues
TDLSSLPTSRDTDAADRSYIGLARQIHAMIASGALEAGARLPSERSLADQFGVSRTQVREAIIALEVQGIVEVRVGSGIY
VSAADAARPVSFELPRGPGPIETLRARGLIEAEVAALAATERKDADLDRLFFSLTTMREQMGDKAAYHAADRQFHLRIAE
STGNTVLLHMVTAMWDCARSDPLWDKIEQHFHSPALREASQEDHQRIFSAIMARDADGAREAMRAHLSRVIAEFTQAWR

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=231, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI87082208, Length=221, Percent_Identity=37.10407239819, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790032, Length=217, Percent_Identity=34.5622119815668, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786303, Length=220, Percent_Identity=31.8181818181818, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789353, Length=222, Percent_Identity=29.2792792792793, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789621, Length=220, Percent_Identity=28.6363636363636, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI48994955, Length=236, Percent_Identity=25.4237288135593, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26438; Mature: 26307

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSSLPTSRDTDAADRSYIGLARQIHAMIASGALEAGARLPSERSLADQFGVSRTQVR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
EAIIALEVQGIVEVRVGSGIYVSAADAARPVSFELPRGPGPIETLRARGLIEAEVAALAA
HHHHHHHHHCEEEEEECCCEEEEECCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHH
TERKDADLDRLFFSLTTMREQMGDKAAYHAADRQFHLRIAESTGNTVLLHMVTAMWDCAR
HCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
SDPLWDKIEQHFHSPALREASQEDHQRIFSAIMARDADGAREAMRAHLSRVIAEFTQAWR
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDLSSLPTSRDTDAADRSYIGLARQIHAMIASGALEAGARLPSERSLADQFGVSRTQVR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
EAIIALEVQGIVEVRVGSGIYVSAADAARPVSFELPRGPGPIETLRARGLIEAEVAALAA
HHHHHHHHHCEEEEEECCCEEEEECCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHH
TERKDADLDRLFFSLTTMREQMGDKAAYHAADRQFHLRIAESTGNTVLLHMVTAMWDCAR
HCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
SDPLWDKIEQHFHSPALREASQEDHQRIFSAIMARDADGAREAMRAHLSRVIAEFTQAWR
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]