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The map label for this gene is btuB [H]

Identifier: 189353096

GI number: 189353096

Start: 1278415

End: 1280331

Strand: Direct

Name: btuB [H]

Synonym: BMULJ_04332

Alternate gene names: 189353096

Gene position: 1278415-1280331 (Clockwise)

Preceding gene: 189353094

Following gene: 189353098

Centisome position: 51.69

GC content: 66.35

Gene sequence:

>1917_bases
ATGAATCTCCGACATCTCCTTGCCACGACCAGCATCACCGCGTTCCTGTCGCCGCTCGCGCACGCCGCCGGCGACGGCGC
GGCGCAGCCGTCGAACGACACCGCGCTGCCGGCCATCACCGTTACCGACACGCGCCATCTGCCCGAATCGTTCGATCGCC
GCTATGCGAGCACGCAGGTGCTCACGCGCGACGATCTCGACCGCCTGTCGCCGAGCGATCCGAGCATCACGCAGGCGCTC
GCGACGCTGCCGGGCGTCACGGTGTCGCAGAACGGCGGTCCGGGCTCGACCGCGTCGGTCAGCATCCGCGGCTCGTCGGC
GAACCAGGTCGCGGTGTTCGTCGACGGCATCCGGATCGGCTCGCCGACCACCGGGATCGCGCCGTGGTCCGACCTGCCGA
CCGAAGCATTCGAACGCGTCGAGGTGATTTCCGGGCCGGCCGCCGCATCGTTCGGCGCAAACGCAATGGGCGGCGTCGTG
CAATTGTTCACACGCCGGGCGTCGAACCAACCGAACCGCACGACGGCATCGTTCGGCGGCGGCTCGAACAAGACGTTCGA
CACGCAGCTGCGCACGTCGGGCACCGTGCCGTCGACCGGACCGCTCGCCGCGCTCGGCGGCCTCACCTACTCGCTCGGCC
TGCACGATTACGCGACGGCCGGCATCGACGCGACGCGGCCGTTCGCATACGGTCACGAGGACGGCCGCAATCCGTACCAC
GCGCAGGACGTCGACGCGCGGCTCGGCTACGCGCGCGACAACTGGTCGGTCTCGACGTTCGCGCTCTATCACCGCTCCGA
TCTGTCGTACGACAATGCCGGCGGCGCGAACCGCGAGCTCGATCATCAGCTGACGACCGGCGTATCGCTCCACGTCGACA
TCACGCCCGACACGCAGTTCGATCAGTCCTTCGGTTATGCGAACGATCGACAGTTCTTCTATGCGGGCGATCGGACCATC
GCGACCGACCGGATCGACTCGCAGCGAATCAGCACGTCGACGTCGCTGACGCATCAGACGCGCGGGCTCACGCTGTTCGG
GCAGCCGCTGTCCGGCGAGACGAAGCTCGCGTACGACTTCACGCGCGAGCAGGCATTCCTGCCGAATGACGTGGCGGGCG
GCGTGCCGACGCGCAACGACTCCGCGTTCTCGCTGCATCAGTCGATCACGCTCGGCAAGGTCACGATGTTCATGGCCGGC
CGTCACGAGATCATCGCCGGCCGCGCGGTGAACACTGGCAACGCGGCGCTCGCATGGGCGATCACGCCCGTCTACACCGC
GCGCGTGTCGTACGGCAACGCATTCCGGCTGCCGACCTTCAACGATCTGTACTACCCCGGTTACGGCAATCCGCGGCTCA
GCCCCGAGCGCAGCAATTCGGTCGAAGCCGCACTCGACGCGAACACGGCGATCGGCACGTTCACGGCCGCGCTCTACGAC
ACGCGCGTTCACAACCTGATCGCATACGATCCCGTCACGTTCGGGCCAATCAATATCGGCCGCGCGCATATTCGCGGGAT
CGATCTGTCGTACAAGGGCACGCTCGGCCGCTCGACGCCTGTCAGCGTTGCGGTCGGCTTCCTGAATCCGCAGGACGTGA
CGAATCGGACATGGTTGAACCGCCGGCCGCGTCAGACGGTCAGCGTCAGCGTCGATCACACGTGGGACGAACTGCATCTG
CATGCGCTGAGCACCGGCGCATCGCTGCTGTACGGCGGCACGACGTTCGACGATCCGGCCAACGCGACCTATCTGCCGTC
GTACCTGACCGTGAGCCTGCGTGCGTCGTACCGGATCAATTCGCATCTGACGGTGTCGGCGCTGCTGTCGAATCTGTTCG
ACCGGCAATACATGACGGCCTACGGTTACAACACGGTCGGCCGCAGCGCGTTCGGCAAGATCACCTATACGTTCTGA

Upstream 100 bases:

>100_bases
ACGTGCCGGCCTCGCCGGGCCACGCCACCGCCGCGCGACAGCGGCGCGCCCTGCGCCCACGTCGCCGCCACGCCCGCATC
ACGATAACGACTCACGCTTC

Downstream 100 bases:

>100_bases
TCGGACCGAGCGCGCTTAGGGACGCTTCGCTGCGCGGCGTTGCTCGAGTCGGTCATCTCGGCGATTCCGATTTGCTGCAT
GCGTCGATGTGCGGCTCGCA

Product: iron complex outer membrane receptor protein

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MNLRHLLATTSITAFLSPLAHAAGDGAAQPSNDTALPAITVTDTRHLPESFDRRYASTQVLTRDDLDRLSPSDPSITQAL
ATLPGVTVSQNGGPGSTASVSIRGSSANQVAVFVDGIRIGSPTTGIAPWSDLPTEAFERVEVISGPAAASFGANAMGGVV
QLFTRRASNQPNRTTASFGGGSNKTFDTQLRTSGTVPSTGPLAALGGLTYSLGLHDYATAGIDATRPFAYGHEDGRNPYH
AQDVDARLGYARDNWSVSTFALYHRSDLSYDNAGGANRELDHQLTTGVSLHVDITPDTQFDQSFGYANDRQFFYAGDRTI
ATDRIDSQRISTSTSLTHQTRGLTLFGQPLSGETKLAYDFTREQAFLPNDVAGGVPTRNDSAFSLHQSITLGKVTMFMAG
RHEIIAGRAVNTGNAALAWAITPVYTARVSYGNAFRLPTFNDLYYPGYGNPRLSPERSNSVEAALDANTAIGTFTAALYD
TRVHNLIAYDPVTFGPINIGRAHIRGIDLSYKGTLGRSTPVSVAVGFLNPQDVTNRTWLNRRPRQTVSVSVDHTWDELHL
HALSTGASLLYGGTTFDDPANATYLPSYLTVSLRASYRINSHLTVSALLSNLFDRQYMTAYGYNTVGRSAFGKITYTF

Sequences:

>Translated_638_residues
MNLRHLLATTSITAFLSPLAHAAGDGAAQPSNDTALPAITVTDTRHLPESFDRRYASTQVLTRDDLDRLSPSDPSITQAL
ATLPGVTVSQNGGPGSTASVSIRGSSANQVAVFVDGIRIGSPTTGIAPWSDLPTEAFERVEVISGPAAASFGANAMGGVV
QLFTRRASNQPNRTTASFGGGSNKTFDTQLRTSGTVPSTGPLAALGGLTYSLGLHDYATAGIDATRPFAYGHEDGRNPYH
AQDVDARLGYARDNWSVSTFALYHRSDLSYDNAGGANRELDHQLTTGVSLHVDITPDTQFDQSFGYANDRQFFYAGDRTI
ATDRIDSQRISTSTSLTHQTRGLTLFGQPLSGETKLAYDFTREQAFLPNDVAGGVPTRNDSAFSLHQSITLGKVTMFMAG
RHEIIAGRAVNTGNAALAWAITPVYTARVSYGNAFRLPTFNDLYYPGYGNPRLSPERSNSVEAALDANTAIGTFTAALYD
TRVHNLIAYDPVTFGPINIGRAHIRGIDLSYKGTLGRSTPVSVAVGFLNPQDVTNRTWLNRRPRQTVSVSVDHTWDELHL
HALSTGASLLYGGTTFDDPANATYLPSYLTVSLRASYRINSHLTVSALLSNLFDRQYMTAYGYNTVGRSAFGKITYTF
>Mature_638_residues
MNLRHLLATTSITAFLSPLAHAAGDGAAQPSNDTALPAITVTDTRHLPESFDRRYASTQVLTRDDLDRLSPSDPSITQAL
ATLPGVTVSQNGGPGSTASVSIRGSSANQVAVFVDGIRIGSPTTGIAPWSDLPTEAFERVEVISGPAAASFGANAMGGVV
QLFTRRASNQPNRTTASFGGGSNKTFDTQLRTSGTVPSTGPLAALGGLTYSLGLHDYATAGIDATRPFAYGHEDGRNPYH
AQDVDARLGYARDNWSVSTFALYHRSDLSYDNAGGANRELDHQLTTGVSLHVDITPDTQFDQSFGYANDRQFFYAGDRTI
ATDRIDSQRISTSTSLTHQTRGLTLFGQPLSGETKLAYDFTREQAFLPNDVAGGVPTRNDSAFSLHQSITLGKVTMFMAG
RHEIIAGRAVNTGNAALAWAITPVYTARVSYGNAFRLPTFNDLYYPGYGNPRLSPERSNSVEAALDANTAIGTFTAALYD
TRVHNLIAYDPVTFGPINIGRAHIRGIDLSYKGTLGRSTPVSVAVGFLNPQDVTNRTWLNRRPRQTVSVSVDHTWDELHL
HALSTGASLLYGGTTFDDPANATYLPSYLTVSLRASYRINSHLTVSALLSNLFDRQYMTAYGYNTVGRSAFGKITYTF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=232, Percent_Identity=31.0344827586207, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786798, Length=194, Percent_Identity=28.8659793814433, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788478, Length=117, Percent_Identity=31.6239316239316, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 68615; Mature: 68615

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRHLLATTSITAFLSPLAHAAGDGAAQPSNDTALPAITVTDTRHLPESFDRRYASTQV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHEE
LTRDDLDRLSPSDPSITQALATLPGVTVSQNGGPGSTASVSIRGSSANQVAVFVDGIRIG
EEHHHHHHCCCCCCHHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCCEEEEEEEEEEEC
SPTTGIAPWSDLPTEAFERVEVISGPAAASFGANAMGGVVQLFTRRASNQPNRTTASFGG
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
GSNKTFDTQLRTSGTVPSTGPLAALGGLTYSLGLHDYATAGIDATRPFAYGHEDGRNPYH
CCCCEEEEEEECCCCCCCCCCHHHHCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCC
AQDVDARLGYARDNWSVSTFALYHRSDLSYDNAGGANRELDHQLTTGVSLHVDITPDTQF
CCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCC
DQSFGYANDRQFFYAGDRTIATDRIDSQRISTSTSLTHQTRGLTLFGQPLSGETKLAYDF
HHHCCCCCCCEEEEECCCEEEECCCCCHHHCCCCCCEECCCCEEEEECCCCCCEEEEEEE
TREQAFLPNDVAGGVPTRNDSAFSLHQSITLGKVTMFMAGRHEIIAGRAVNTGNAALAWA
CCCCCCCCCCCCCCCCCCCCCCEEEECCEEECEEEEEECCCCEEEEEEEECCCCCEEEEE
ITPVYTARVSYGNAFRLPTFNDLYYPGYGNPRLSPERSNSVEAALDANTAIGTFTAALYD
EEEEEEEEECCCCEECCCCCCCEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
TRVHNLIAYDPVTFGPINIGRAHIRGIDLSYKGTLGRSTPVSVAVGFLNPQDVTNRTWLN
HHHHCEEEECCEEECCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCHHCC
RRPRQTVSVSVDHTWDELHLHALSTGASLLYGGTTFDDPANATYLPSYLTVSLRASYRIN
CCCCCEEEEEECCCCCCEEEEEECCCCEEEECCCCCCCCCCCEECCCEEEEEEEEEEEEC
SHLTVSALLSNLFDRQYMTAYGYNTVGRSAFGKITYTF
CCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MNLRHLLATTSITAFLSPLAHAAGDGAAQPSNDTALPAITVTDTRHLPESFDRRYASTQV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHEE
LTRDDLDRLSPSDPSITQALATLPGVTVSQNGGPGSTASVSIRGSSANQVAVFVDGIRIG
EEHHHHHHCCCCCCHHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCCEEEEEEEEEEEC
SPTTGIAPWSDLPTEAFERVEVISGPAAASFGANAMGGVVQLFTRRASNQPNRTTASFGG
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
GSNKTFDTQLRTSGTVPSTGPLAALGGLTYSLGLHDYATAGIDATRPFAYGHEDGRNPYH
CCCCEEEEEEECCCCCCCCCCHHHHCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCC
AQDVDARLGYARDNWSVSTFALYHRSDLSYDNAGGANRELDHQLTTGVSLHVDITPDTQF
CCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCC
DQSFGYANDRQFFYAGDRTIATDRIDSQRISTSTSLTHQTRGLTLFGQPLSGETKLAYDF
HHHCCCCCCCEEEEECCCEEEECCCCCHHHCCCCCCEECCCCEEEEECCCCCCEEEEEEE
TREQAFLPNDVAGGVPTRNDSAFSLHQSITLGKVTMFMAGRHEIIAGRAVNTGNAALAWA
CCCCCCCCCCCCCCCCCCCCCCEEEECCEEECEEEEEECCCCEEEEEEEECCCCCEEEEE
ITPVYTARVSYGNAFRLPTFNDLYYPGYGNPRLSPERSNSVEAALDANTAIGTFTAALYD
EEEEEEEEECCCCEECCCCCCCEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
TRVHNLIAYDPVTFGPINIGRAHIRGIDLSYKGTLGRSTPVSVAVGFLNPQDVTNRTWLN
HHHHCEEEECCEEECCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCHHCC
RRPRQTVSVSVDHTWDELHLHALSTGASLLYGGTTFDDPANATYLPSYLTVSLRASYRIN
CCCCCEEEEEECCCCCCEEEEEECCCCEEEECCCCCCCCCCCEECCCEEEEEEEEEEEEC
SHLTVSALLSNLFDRQYMTAYGYNTVGRSAFGKITYTF
CCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA