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The map label for this gene is hcrC [H]

Identifier: 189353071

GI number: 189353071

Start: 1243480

End: 1244148

Strand: Reverse

Name: hcrC [H]

Synonym: BMULJ_04305

Alternate gene names: 189353071

Gene position: 1244148-1243480 (Counterclockwise)

Preceding gene: 189353072

Following gene: 189353070

Centisome position: 50.31

GC content: 68.01

Gene sequence:

>669_bases
ATGACGACCGCCCAAACCGACGCGTCGGGCGCGAGCGCCGCCGCGGCAGCGACCGGCGCATCCGCGCCGAACGCGGCTTC
GGCCGCATCCGCCGCGGCCGCCGTCGAGCGTCCGCTGGTCCGCTTCCAGCAGAAGCCGCTGTCGGTCAACATCAACGGCA
AGGCCGTCGGCCCGATGCAGGTGCCGGAAGGGCTGATGATGATCGAGTTCCTGCACGAGTATGCGGGGCTCACGGGTTCG
CGGCTCGGCTGCGGGCAGGGGATCTGCCACGCGTGCGTGGTGATTCTCGACAAGCCGGACGGCACGAGCGAGGAAGTGCG
CACCTGCATCACCGGCGCGCATTTCTTCCACGGGCGTGCGATCCGCACGGTCGAAGGCCATGCGAAGCGCAACGAAGCCG
GCGAAGTGGTCGAGCTGTCGCCGATCCAGCAGAAGTTCCTCGAGCACTTCAGCTTCCAGTGCGGCTACTGCACGCCCGGC
TTCGTGAACGCGGCGACGGTGCTGATCGAGCGGCTGAAGCGCGAGCCGATCGCGAAGGCCGACGTCGAGCGCACGATCAC
CGAGGCGCTGAACGCGCATCTGTGCCGCTGCACGGGCTACGTCCGCTACTACCAAGCCGTGAAGGACGTCGTGATGACGA
CGCCGGGACTCGTAAAGGACGCCGCATGA

Upstream 100 bases:

>100_bases
TTCCCGTCGTCGGCGCGATCGTGAACGGCATCGCTCACGCGACCGGCCATCGTTTCACCGATCTGCCGGTGACCCCGCAA
AAGATTCAGGAGGTGCTCGC

Downstream 100 bases:

>100_bases
AACGCACACTCGCTCATCGTGTCGCGCGCTTCGCCGGCTTGCCCGCGCTCGCCGCGGCGTGCGCACTGACGCTCGCCGCG
TGCGGCGGCGACGCACCCGC

Product: 4-hydroxybenzoyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTTAQTDASGASAAAAATGASAPNAASAASAAAAVERPLVRFQQKPLSVNINGKAVGPMQVPEGLMMIEFLHEYAGLTGS
RLGCGQGICHACVVILDKPDGTSEEVRTCITGAHFFHGRAIRTVEGHAKRNEAGEVVELSPIQQKFLEHFSFQCGYCTPG
FVNAATVLIERLKREPIAKADVERTITEALNAHLCRCTGYVRYYQAVKDVVMTTPGLVKDAA

Sequences:

>Translated_222_residues
MTTAQTDASGASAAAAATGASAPNAASAASAAAAVERPLVRFQQKPLSVNINGKAVGPMQVPEGLMMIEFLHEYAGLTGS
RLGCGQGICHACVVILDKPDGTSEEVRTCITGAHFFHGRAIRTVEGHAKRNEAGEVVELSPIQQKFLEHFSFQCGYCTPG
FVNAATVLIERLKREPIAKADVERTITEALNAHLCRCTGYVRYYQAVKDVVMTTPGLVKDAA
>Mature_221_residues
TTAQTDASGASAAAAATGASAPNAASAASAAAAVERPLVRFQQKPLSVNINGKAVGPMQVPEGLMMIEFLHEYAGLTGSR
LGCGQGICHACVVILDKPDGTSEEVRTCITGAHFFHGRAIRTVEGHAKRNEAGEVVELSPIQQKFLEHFSFQCGYCTPGF
VNAATVLIERLKREPIAKADVERTITEALNAHLCRCTGYVRYYQAVKDVVMTTPGLVKDAA

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789232, Length=165, Percent_Identity=33.9393939393939, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1786480, Length=196, Percent_Identity=28.0612244897959, Blast_Score=84, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32566215, Length=156, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=32.6923076923077, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=178, Percent_Identity=29.2134831460674, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17737937, Length=155, Percent_Identity=31.6129032258064, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647193, Length=167, Percent_Identity=31.1377245508982, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24647199, Length=163, Percent_Identity=30.0613496932515, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647195, Length=169, Percent_Identity=29.585798816568, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647197, Length=169, Percent_Identity=29.585798816568, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 23505; Mature: 23374

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAQTDASGASAAAAATGASAPNAASAASAAAAVERPLVRFQQKPLSVNINGKAVGPMQ
CCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCC
VPEGLMMIEFLHEYAGLTGSRLGCGQGICHACVVILDKPDGTSEEVRTCITGAHFFHGRA
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCE
IRTVEGHAKRNEAGEVVELSPIQQKFLEHFSFQCGYCTPGFVNAATVLIERLKREPIAKA
EEEECCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
DVERTITEALNAHLCRCTGYVRYYQAVKDVVMTTPGLVKDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure 
TTAQTDASGASAAAAATGASAPNAASAASAAAAVERPLVRFQQKPLSVNINGKAVGPMQ
CCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCC
VPEGLMMIEFLHEYAGLTGSRLGCGQGICHACVVILDKPDGTSEEVRTCITGAHFFHGRA
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCE
IRTVEGHAKRNEAGEVVELSPIQQKFLEHFSFQCGYCTPGFVNAATVLIERLKREPIAKA
EEEECCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
DVERTITEALNAHLCRCTGYVRYYQAVKDVVMTTPGLVKDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]