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The map label for this gene is ytnA [H]

Identifier: 189353022

GI number: 189353022

Start: 1188080

End: 1189459

Strand: Direct

Name: ytnA [H]

Synonym: BMULJ_04256

Alternate gene names: 189353022

Gene position: 1188080-1189459 (Clockwise)

Preceding gene: 189353021

Following gene: 189353023

Centisome position: 48.04

GC content: 65.36

Gene sequence:

>1380_bases
TTGAAACAGCAAGAAGACCAGCTTCACCGCGGGCTGGAAGAACGGCACATCAACCTGATGGCGCTCGGCGCGACGATCGG
CGTCGGCCTGTTCCTCGGCTCGGCCACCGCGATCCGCGCGGCCGGCCCCGCGATCCTGCTGACCTATCTGCTCGGCGGCA
TCGTGATCTTCCTGATCATGCGCGCGCTTGGCGAAATGGCGATCACCAATCCCGTCGCGGGCGCGTTCAGCCGCTATGCG
CGCGACTATCTCGGCCCGCTCGCGGGCTATCTGACCGGCTGGACCTACTGGTTCGTCTGGATCGTCACCTGCATGGCCGA
GATCACCGCAGTCGGCGTCTACATGCACATGTGGTTCCCCGCCGTACCGAACTGGATCTGGGCGCTCGCCGCGCTCAGCG
CGATGGGCGCGGTGAACTTCATCGCGGTCAAGCTGTACGGCGAATTCGAGTTCTGGTTCGCGCTGATCAAGATCGTCACG
ATCGTGCTGATGATCGTCGGCGGTGCGCTGATGATCGTGTTCGGGATCGGCAACGGCGGCGTCGCGACCGGCATTTCGAA
CCTCTGGACTCACGGCGGCTTCATGCCGCACGGCATCGGCGGCGTGATCGACGCGCTGCCGATCGTGATGTTCGCGTATC
TCGGCGTCGAAATGCTCGGCCTCACCGCGGGCGAAGCGCGCAACCCCGAGAAGTCGCTGACGAAGGCCGTGAACTCGGTG
TTCTGGCGCGTGCTGATTTTCTACATCGGCGCGCTGTCGGTGATCATGTCGATCTATCCGTGGGACCAGATCGGCACGCA
GGGCAGCCCGTTCGTGATGACGTTCTCGCGGCTCGGCATTCCGGCCGCGGCCGGCATCATCAACTTCGTCGTGCTGACGG
CGGCGCTGTCGTCGTGCAACAGCGGCCTGTTCAGCACCGCGCGGATGCTCTACAACCTCGCGCAGCAAGGCCAGGCCCCG
CGCGTGCTCGGCCGCGTCAATGCGAGCGGCGTGCCCGTCTATGGCGTGATCGTCTCGGTCGCGCTGCTGCTGGTCGGCGT
GCTGCTGAACTATCTCGCGCCGCAGCACGTCTTCGTGTGGCTCACGTCGGTGTCGACGTTCGGCGCGATCTGGACGTGGT
GCGTGATCCTGATCGCGCAGATGCGCTTTCGCCGCACGCTGTCGGCCGACCGCATCGCGCGCCTGCCGATTCGCGTGCCG
TTCTATCCGCTCGGCTCGTACGTGGCGCTCGCGTTTCTCGCGTTCGTCGTCGTGCTGATGGCGTTCACGCCCGATACGCG
CGTCGCGCTCGTGATCGGCCCGCTGTGGATCGTGCTGCTCGGTATCGCGTACACGATGTTCTACGCGAATCGCCCCGCGG
TATCGACGCCGAAGTCCTGA

Upstream 100 bases:

>100_bases
GCGCCTCCTTTTCGTTTTCGGCAGCCGATAACGGCATCGACGCTCGCGCATCGACTTCGACACAATGACGCGGCCGCCGT
GCGGCCGCCAGGAGACGGAC

Downstream 100 bases:

>100_bases
GCGGCCGACGCCCGCGCGCGTCCTGCGTGCGGCATCCGGGCCCGCGCGTGCGCTGATCTCGATCATGCACGCACGGGCCG
ATACGCTTTATCCTGTCCCG

Product: AAT family amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKQQEDQLHRGLEERHINLMALGATIGVGLFLGSATAIRAAGPAILLTYLLGGIVIFLIMRALGEMAITNPVAGAFSRYA
RDYLGPLAGYLTGWTYWFVWIVTCMAEITAVGVYMHMWFPAVPNWIWALAALSAMGAVNFIAVKLYGEFEFWFALIKIVT
IVLMIVGGALMIVFGIGNGGVATGISNLWTHGGFMPHGIGGVIDALPIVMFAYLGVEMLGLTAGEARNPEKSLTKAVNSV
FWRVLIFYIGALSVIMSIYPWDQIGTQGSPFVMTFSRLGIPAAAGIINFVVLTAALSSCNSGLFSTARMLYNLAQQGQAP
RVLGRVNASGVPVYGVIVSVALLLVGVLLNYLAPQHVFVWLTSVSTFGAIWTWCVILIAQMRFRRTLSADRIARLPIRVP
FYPLGSYVALAFLAFVVVLMAFTPDTRVALVIGPLWIVLLGIAYTMFYANRPAVSTPKS

Sequences:

>Translated_459_residues
MKQQEDQLHRGLEERHINLMALGATIGVGLFLGSATAIRAAGPAILLTYLLGGIVIFLIMRALGEMAITNPVAGAFSRYA
RDYLGPLAGYLTGWTYWFVWIVTCMAEITAVGVYMHMWFPAVPNWIWALAALSAMGAVNFIAVKLYGEFEFWFALIKIVT
IVLMIVGGALMIVFGIGNGGVATGISNLWTHGGFMPHGIGGVIDALPIVMFAYLGVEMLGLTAGEARNPEKSLTKAVNSV
FWRVLIFYIGALSVIMSIYPWDQIGTQGSPFVMTFSRLGIPAAAGIINFVVLTAALSSCNSGLFSTARMLYNLAQQGQAP
RVLGRVNASGVPVYGVIVSVALLLVGVLLNYLAPQHVFVWLTSVSTFGAIWTWCVILIAQMRFRRTLSADRIARLPIRVP
FYPLGSYVALAFLAFVVVLMAFTPDTRVALVIGPLWIVLLGIAYTMFYANRPAVSTPKS
>Mature_459_residues
MKQQEDQLHRGLEERHINLMALGATIGVGLFLGSATAIRAAGPAILLTYLLGGIVIFLIMRALGEMAITNPVAGAFSRYA
RDYLGPLAGYLTGWTYWFVWIVTCMAEITAVGVYMHMWFPAVPNWIWALAALSAMGAVNFIAVKLYGEFEFWFALIKIVT
IVLMIVGGALMIVFGIGNGGVATGISNLWTHGGFMPHGIGGVIDALPIVMFAYLGVEMLGLTAGEARNPEKSLTKAVNSV
FWRVLIFYIGALSVIMSIYPWDQIGTQGSPFVMTFSRLGIPAAAGIINFVVLTAALSSCNSGLFSTARMLYNLAQQGQAP
RVLGRVNASGVPVYGVIVSVALLLVGVLLNYLAPQHVFVWLTSVSTFGAIWTWCVILIAQMRFRRTLSADRIARLPIRVP
FYPLGSYVALAFLAFVVVLMAFTPDTRVALVIGPLWIVLLGIAYTMFYANRPAVSTPKS

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=436, Percent_Identity=20.6422018348624, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI258614005, Length=437, Percent_Identity=20.5949656750572, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI258614003, Length=437, Percent_Identity=20.5949656750572, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI114326544, Length=430, Percent_Identity=21.1627906976744, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI114326550, Length=430, Percent_Identity=21.1627906976744, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI181337167, Length=340, Percent_Identity=22.0588235294118, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI48994972, Length=453, Percent_Identity=51.6556291390728, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1786602, Length=442, Percent_Identity=50.9049773755656, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1786302, Length=455, Percent_Identity=44.8351648351648, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1786789, Length=444, Percent_Identity=46.6216216216216, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1790653, Length=455, Percent_Identity=42.8571428571429, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI87081915, Length=447, Percent_Identity=40.0447427293065, Blast_Score=334, Evalue=6e-93,
Organism=Escherichia coli, GI1789017, Length=431, Percent_Identity=37.5870069605568, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI87081708, Length=455, Percent_Identity=36.9230769230769, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1788480, Length=435, Percent_Identity=37.4712643678161, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI87081869, Length=192, Percent_Identity=23.9583333333333, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI2367353, Length=371, Percent_Identity=23.989218328841, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790575, Length=291, Percent_Identity=26.1168384879725, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=364, Percent_Identity=23.3516483516484, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=357, Percent_Identity=21.5686274509804, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17540018, Length=457, Percent_Identity=24.945295404814, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=424, Percent_Identity=21.4622641509434, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=441, Percent_Identity=32.4263038548753, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320772, Length=447, Percent_Identity=32.662192393736, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6324924, Length=448, Percent_Identity=31.9196428571429, Blast_Score=213, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6324059, Length=440, Percent_Identity=32.2727272727273, Blast_Score=200, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6324990, Length=446, Percent_Identity=28.9237668161435, Blast_Score=189, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6322892, Length=434, Percent_Identity=31.5668202764977, Blast_Score=189, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6319824, Length=401, Percent_Identity=28.1795511221945, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6321053, Length=468, Percent_Identity=29.0598290598291, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6320717, Length=404, Percent_Identity=26.7326732673267, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324553, Length=395, Percent_Identity=29.620253164557, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321629, Length=419, Percent_Identity=26.0143198090692, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319542, Length=399, Percent_Identity=28.8220551378446, Blast_Score=166, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6320251, Length=402, Percent_Identity=27.363184079602, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6319543, Length=400, Percent_Identity=27, Blast_Score=163, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6322967, Length=401, Percent_Identity=27.6807980049875, Blast_Score=163, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6319608, Length=442, Percent_Identity=28.0542986425339, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324981, Length=405, Percent_Identity=26.4197530864197, Blast_Score=146, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320364, Length=503, Percent_Identity=24.8508946322068, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221512776, Length=421, Percent_Identity=19.9524940617577, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24666159, Length=421, Percent_Identity=19.9524940617577, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24667468, Length=424, Percent_Identity=24.0566037735849, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668806, Length=413, Percent_Identity=22.0338983050847, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356285, Length=413, Percent_Identity=22.0338983050847, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24668802, Length=413, Percent_Identity=22.0338983050847, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI161077963, Length=377, Percent_Identity=23.342175066313, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49733; Mature: 49733

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQEDQLHRGLEERHINLMALGATIGVGLFLGSATAIRAAGPAILLTYLLGGIVIFLIM
CCCCHHHHHCCHHHHCCHHEEEHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHH
RALGEMAITNPVAGAFSRYARDYLGPLAGYLTGWTYWFVWIVTCMAEITAVGVYMHMWFP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVPNWIWALAALSAMGAVNFIAVKLYGEFEFWFALIKIVTIVLMIVGGALMIVFGIGNGG
HHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCH
VATGISNLWTHGGFMPHGIGGVIDALPIVMFAYLGVEMLGLTAGEARNPEKSLTKAVNSV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FWRVLIFYIGALSVIMSIYPWDQIGTQGSPFVMTFSRLGIPAAAGIINFVVLTAALSSCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHC
SGLFSTARMLYNLAQQGQAPRVLGRVNASGVPVYGVIVSVALLLVGVLLNYLAPQHVFVW
CHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LTSVSTFGAIWTWCVILIAQMRFRRTLSADRIARLPIRVPFYPLGSYVALAFLAFVVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
AFTPDTRVALVIGPLWIVLLGIAYTMFYANRPAVSTPKS
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKQQEDQLHRGLEERHINLMALGATIGVGLFLGSATAIRAAGPAILLTYLLGGIVIFLIM
CCCCHHHHHCCHHHHCCHHEEEHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHH
RALGEMAITNPVAGAFSRYARDYLGPLAGYLTGWTYWFVWIVTCMAEITAVGVYMHMWFP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVPNWIWALAALSAMGAVNFIAVKLYGEFEFWFALIKIVTIVLMIVGGALMIVFGIGNGG
HHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCH
VATGISNLWTHGGFMPHGIGGVIDALPIVMFAYLGVEMLGLTAGEARNPEKSLTKAVNSV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FWRVLIFYIGALSVIMSIYPWDQIGTQGSPFVMTFSRLGIPAAAGIINFVVLTAALSSCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHC
SGLFSTARMLYNLAQQGQAPRVLGRVNASGVPVYGVIVSVALLLVGVLLNYLAPQHVFVW
CHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LTSVSTFGAIWTWCVILIAQMRFRRTLSADRIARLPIRVPFYPLGSYVALAFLAFVVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
AFTPDTRVALVIGPLWIVLLGIAYTMFYANRPAVSTPKS
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]