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The map label for this gene is fnr [H]

Identifier: 189353007

GI number: 189353007

Start: 1170989

End: 1171768

Strand: Reverse

Name: fnr [H]

Synonym: BMULJ_04241

Alternate gene names: 189353007

Gene position: 1171768-1170989 (Counterclockwise)

Preceding gene: 189353008

Following gene: 189353002

Centisome position: 47.38

GC content: 66.67

Gene sequence:

>780_bases
ATGTCCACTGCTACCGCCAGCGTCCTCGACGCGCCCGTGATCGCCCCGCAACCGATTGAGCTTCACGCCCTCGCGCGCGC
CGATTCGGCCAAGCCGGCGGCCACGCGCTGCTCGGCGTGCGCGATGCGCGCGATGTGCCTGCCGCCGCATCTGACCGCGG
CCGAATACAGCCGGCTCGACGCGATCATCTGTGCGACACGCCATGTGCGTCAGGGCGATGCGCTGTTCCGCGCGGACGAT
CCGTTCCACAGCCTGTACGCGGTGCGCGCCGGCTCGTTCAAGACGGTGATGATGCATCGCGACGGCCGCGAGCACGTGAC
GGGTTTCCAGATCGCCGGCGAAACGCTCGGCCTCGACGGCATCGGCAGCGGTCAGCACTGCTGCGACGCGATCGCGCTCG
AGGACAGCGTCGTGTGCATCATCCCGTTCGACGCGCTCGAAGCGGCGTGCCGCGAGATCAAGCCGATGCAGCAGTTTCTC
TATCAGCTGCTCAGCAGCGAGATCGTGCGCGAATCGAGCCAGATGCTGCTGCTCGGCACGATGTCGGCCGAGCAGCGCGT
CGCGCATTTTCTGCTGAATCTGTCGTCGCGCTTCCAGGCGCGCGGCTATTCGGCGTCGGAATTCAATCTGCGGATGACGC
GCGAGGAAATCGGCTGCTATCTCGGGATGAAGCTGGAAACGGTCAGCCGGATGTTCTCGCGCTTCCATCGCGACGCGCTC
GTCGAAACGCGCGGCAAGCGCGTGCGGATTCTCGACGCGCAGGCGCTCGCCCGCGTGTGA

Upstream 100 bases:

>100_bases
ATTTCTTCGACAAGACCGTCGAGTTCGACGCCGCCTGCCGCCTGATCGAATCGCTGGTGCACGCGCGCGCGCACCGACCC
TGACCGTGCCGGAGTGTCTC

Downstream 100 bases:

>100_bases
CGCACGCGAACCGACGCGCGCCGGCGGCGGCCCGTTCGCGGCCGGCCGCGGCGCGTGAAGCTCAGACGTTGAACGCCTGC
GACATCTTCAGTTCGATCCA

Product: CRP/FNR family anaerobic regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSTATASVLDAPVIAPQPIELHALARADSAKPAATRCSACAMRAMCLPPHLTAAEYSRLDAIICATRHVRQGDALFRADD
PFHSLYAVRAGSFKTVMMHRDGREHVTGFQIAGETLGLDGIGSGQHCCDAIALEDSVVCIIPFDALEAACREIKPMQQFL
YQLLSSEIVRESSQMLLLGTMSAEQRVAHFLLNLSSRFQARGYSASEFNLRMTREEIGCYLGMKLETVSRMFSRFHRDAL
VETRGKRVRILDAQALARV

Sequences:

>Translated_259_residues
MSTATASVLDAPVIAPQPIELHALARADSAKPAATRCSACAMRAMCLPPHLTAAEYSRLDAIICATRHVRQGDALFRADD
PFHSLYAVRAGSFKTVMMHRDGREHVTGFQIAGETLGLDGIGSGQHCCDAIALEDSVVCIIPFDALEAACREIKPMQQFL
YQLLSSEIVRESSQMLLLGTMSAEQRVAHFLLNLSSRFQARGYSASEFNLRMTREEIGCYLGMKLETVSRMFSRFHRDAL
VETRGKRVRILDAQALARV
>Mature_258_residues
STATASVLDAPVIAPQPIELHALARADSAKPAATRCSACAMRAMCLPPHLTAAEYSRLDAIICATRHVRQGDALFRADDP
FHSLYAVRAGSFKTVMMHRDGREHVTGFQIAGETLGLDGIGSGQHCCDAIALEDSVVCIIPFDALEAACREIKPMQQFLY
QLLSSEIVRESSQMLLLGTMSAEQRVAHFLLNLSSRFQARGYSASEFNLRMTREEIGCYLGMKLETVSRMFSRFHRDALV
ETRGKRVRILDAQALARV

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=226, Percent_Identity=40.7079646017699, Blast_Score=190, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28548; Mature: 28417

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATASVLDAPVIAPQPIELHALARADSAKPAATRCSACAMRAMCLPPHLTAAEYSRLD
CCCCHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AIICATRHVRQGDALFRADDPFHSLYAVRAGSFKTVMMHRDGREHVTGFQIAGETLGLDG
HHHHHHHHCCCCCCEEECCCCHHHHHHEECCCEEEEEEECCCCHHCCCEEEECCEECCCC
IGSGQHCCDAIALEDSVVCIIPFDALEAACREIKPMQQFLYQLLSSEIVRESSQMLLLGT
CCCCHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
MSAEQRVAHFLLNLSSRFQARGYSASEFNLRMTREEIGCYLGMKLETVSRMFSRFHRDAL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCHHHCCHHHHHHHHHHHHHHHHH
VETRGKRVRILDAQALARV
HHCCCCEEEEECHHHHHCC
>Mature Secondary Structure 
STATASVLDAPVIAPQPIELHALARADSAKPAATRCSACAMRAMCLPPHLTAAEYSRLD
CCCHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AIICATRHVRQGDALFRADDPFHSLYAVRAGSFKTVMMHRDGREHVTGFQIAGETLGLDG
HHHHHHHHCCCCCCEEECCCCHHHHHHEECCCEEEEEEECCCCHHCCCEEEECCEECCCC
IGSGQHCCDAIALEDSVVCIIPFDALEAACREIKPMQQFLYQLLSSEIVRESSQMLLLGT
CCCCHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
MSAEQRVAHFLLNLSSRFQARGYSASEFNLRMTREEIGCYLGMKLETVSRMFSRFHRDAL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCHHHCCHHHHHHHHHHHHHHHHH
VETRGKRVRILDAQALARV
HHCCCCEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]