BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is budC [H]

Identifier: 189352996

GI number: 189352996

Start: 1159345

End: 1160142

Strand: Reverse

Name: budC [H]

Synonym: BMULJ_04230

Alternate gene names: 189352996

Gene position: 1160142-1159345 (Counterclockwise)

Preceding gene: 189352997

Following gene: 189352995

Centisome position: 46.91

GC content: 69.67

Gene sequence:

>798_bases
ATGACCGCTTCCGACCTGCTGAAACCCTATGACGGCCTTCGCGTCCTCGTGACCGGCGGCGCATCCGGCATCGGCCTCGC
CATCGCCGATGCGTTCGCCGAATGCGGTGCGCGCGTGCATGTCTGCGACGCGTCGCAGGCCGCGATCGCGGCGCTCGCCG
ACCGGCCGTCGCGTGCCGCGATCGGCGCAACGCTTGCCGACGTATCGGACCGCGCGGCGGTCGAGCGCGTGTTCGCGGAC
GTCGCGGCAACGCTCGGCGGCCTCGACGTACTGGTCAACAACGCGGGCATCGCGGGCCCGACCGGCGGCATCGACGAGAT
CGATCCCGCGCAGTGGGAGCAGACGGTCGCGATCAATCTGAACGCGCAATTCGAATTCGCGCGACGCGCTGTGCCGCTGC
TGCGCGAGTCGAAGCACGGTGGCGCCATCATCGCGCTGTCGTCGGTCGCGGGCCGGCTCGGCTATGCGTACCGCACGCCT
TACGCGGCCACCAAATGGGCGGTCGTCGGTCTCGTGAAGAGCCTCGCGATCGAACTGGGGCCGCTCGGCATTCGCGTGAA
TGCGATCCAGCCCGGCATCGTGCGCGGCCCGCGCATCCGCCGCGTGATCGAAGCGCGCGCGCAACAGCTCGGCATCGGCT
ACGACGAGATGGAGCAGCGCTATCTCGAACGGATTTCGCTGCGCCGGATGACCGAGCCGGCCGAAATCGCGGCGACCGCG
CTGTTCCTGTGCTCGCCCGGCGGGCACGGCATCACCGGCCAGGCGATCTCCGTCTGCGGCAACGTCGAAGTGCTCTGA

Upstream 100 bases:

>100_bases
TGCGTGCCGAGCAGGCGCCGCGCCGCGTGAACGCCAAACCGTAACGCCGCGCGCAACGGCGCGCCGCATCCGACAACATC
AACGATGGAGACAACCGCGC

Downstream 100 bases:

>100_bases
GCCCTCCTGCACCGTCCACCGAAAGGAACCGATCCGTGGCAAACGCTCGCAAAGTCATCATCACCTGTGCGCCGACCGGC
GCGATCCATACGCCGTCGAT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTASDLLKPYDGLRVLVTGGASGIGLAIADAFAECGARVHVCDASQAAIAALADRPSRAAIGATLADVSDRAAVERVFAD
VAATLGGLDVLVNNAGIAGPTGGIDEIDPAQWEQTVAINLNAQFEFARRAVPLLRESKHGGAIIALSSVAGRLGYAYRTP
YAATKWAVVGLVKSLAIELGPLGIRVNAIQPGIVRGPRIRRVIEARAQQLGIGYDEMEQRYLERISLRRMTEPAEIAATA
LFLCSPGGHGITGQAISVCGNVEVL

Sequences:

>Translated_265_residues
MTASDLLKPYDGLRVLVTGGASGIGLAIADAFAECGARVHVCDASQAAIAALADRPSRAAIGATLADVSDRAAVERVFAD
VAATLGGLDVLVNNAGIAGPTGGIDEIDPAQWEQTVAINLNAQFEFARRAVPLLRESKHGGAIIALSSVAGRLGYAYRTP
YAATKWAVVGLVKSLAIELGPLGIRVNAIQPGIVRGPRIRRVIEARAQQLGIGYDEMEQRYLERISLRRMTEPAEIAATA
LFLCSPGGHGITGQAISVCGNVEVL
>Mature_264_residues
TASDLLKPYDGLRVLVTGGASGIGLAIADAFAECGARVHVCDASQAAIAALADRPSRAAIGATLADVSDRAAVERVFADV
AATLGGLDVLVNNAGIAGPTGGIDEIDPAQWEQTVAINLNAQFEFARRAVPLLRESKHGGAIIALSSVAGRLGYAYRTPY
AATKWAVVGLVKSLAIELGPLGIRVNAIQPGIVRGPRIRRVIEARAQQLGIGYDEMEQRYLERISLRRMTEPAEIAATAL
FLCSPGGHGITGQAISVCGNVEVL

Specific function: Catalyzes the reversible reduction of (S)-acetoin to 2,3-butanediol in the presence of NADH [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.9317269076305, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=31.2741312741313, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=30, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=30.2788844621514, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI31542939, Length=236, Percent_Identity=31.3559322033898, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=26.7716535433071, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI126723750, Length=269, Percent_Identity=29.368029739777, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=32.1608040201005, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI142976729, Length=199, Percent_Identity=28.1407035175879, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=29.9610894941634, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI210032110, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=31.8918918918919, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=29.9465240641711, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=26.3374485596708, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=33.8541666666667, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4504503, Length=191, Percent_Identity=31.413612565445, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=32.5581395348837, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4503301, Length=207, Percent_Identity=27.536231884058, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI40548397, Length=262, Percent_Identity=27.8625954198473, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI214010158, Length=262, Percent_Identity=27.8625954198473, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI214010156, Length=262, Percent_Identity=27.8625954198473, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI22758144, Length=262, Percent_Identity=27.8625954198473, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4758504, Length=208, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=28.2868525896414, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI157739938, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI38348362, Length=172, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI302344755, Length=110, Percent_Identity=34.5454545454545, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI38424085, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.9352226720648, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=25.7281553398058, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787905, Length=263, Percent_Identity=33.4600760456274, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=31.0756972111554, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=29.8804780876494, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=35.8870967741936, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=32.5581395348837, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=29.1666666666667, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=28.1746031746032, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.9212598425197, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=31.6205533596838, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=32.9787234042553, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367175, Length=262, Percent_Identity=29.3893129770992, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788459, Length=176, Percent_Identity=30.6818181818182, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787526, Length=188, Percent_Identity=31.3829787234043, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=24.5136186770428, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=32.7868852459016, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=35.8870967741936, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=31.7269076305221, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=33.6032388663968, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=29.4339622641509, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=210, Percent_Identity=34.7619047619048, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=30.2681992337165, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=197, Percent_Identity=33.502538071066, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=190, Percent_Identity=33.6842105263158, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=174, Percent_Identity=31.6091954022989, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=198, Percent_Identity=31.8181818181818, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=28.2945736434109, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=196, Percent_Identity=29.5918367346939, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=195, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=29.1828793774319, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=193, Percent_Identity=31.6062176165803, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=284, Percent_Identity=28.169014084507, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=31.6326530612245, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=27.1653543307087, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=199, Percent_Identity=28.1407035175879, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=179, Percent_Identity=32.4022346368715, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=173, Percent_Identity=32.3699421965318, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=190, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=234, Percent_Identity=24.7863247863248, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=200, Percent_Identity=32, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=169, Percent_Identity=28.4023668639053, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=29.296875, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=187, Percent_Identity=28.8770053475936, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=194, Percent_Identity=28.8659793814433, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=30, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=202, Percent_Identity=26.2376237623762, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=190, Percent_Identity=31.0526315789474, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=27.4131274131274, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=29.9465240641711, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=221, Percent_Identity=25.7918552036199, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=27.2251308900524, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=30.5555555555556, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=31.3008130081301, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=30.2325581395349, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=31.1023622047244, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=29.9212598425197, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281364892, Length=205, Percent_Identity=32.1951219512195, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644337, Length=187, Percent_Identity=35.2941176470588, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=28.8537549407115, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643142, Length=267, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=31, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581726, Length=214, Percent_Identity=30.8411214953271, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665243, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331218, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356301, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.304 [H]

Molecular weight: Translated: 27607; Mature: 27476

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00061 ADH_SHORT ; PS00196 COPPER_BLUE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASDLLKPYDGLRVLVTGGASGIGLAIADAFAECGARVHVCDASQAAIAALADRPSRAA
CCHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCHHH
IGATLADVSDRAAVERVFADVAATLGGLDVLVNNAGIAGPTGGIDEIDPAQWEQTVAINL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
NAQFEFARRAVPLLRESKHGGAIIALSSVAGRLGYAYRTPYAATKWAVVGLVKSLAIELG
CCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHCC
PLGIRVNAIQPGIVRGPRIRRVIEARAQQLGIGYDEMEQRYLERISLRRMTEPAEIAATA
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHE
LFLCSPGGHGITGQAISVCGNVEVL
EEEECCCCCCCCCHHHHHCCCEEEC
>Mature Secondary Structure 
TASDLLKPYDGLRVLVTGGASGIGLAIADAFAECGARVHVCDASQAAIAALADRPSRAA
CHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCHHH
IGATLADVSDRAAVERVFADVAATLGGLDVLVNNAGIAGPTGGIDEIDPAQWEQTVAINL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
NAQFEFARRAVPLLRESKHGGAIIALSSVAGRLGYAYRTPYAATKWAVVGLVKSLAIELG
CCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHCC
PLGIRVNAIQPGIVRGPRIRRVIEARAQQLGIGYDEMEQRYLERISLRRMTEPAEIAATA
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHE
LFLCSPGGHGITGQAISVCGNVEVL
EEEECCCCCCCCCHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11173520 [H]