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The map label for this gene is ttuB [H]

Identifier: 189352994

GI number: 189352994

Start: 1156827

End: 1158155

Strand: Reverse

Name: ttuB [H]

Synonym: BMULJ_04228

Alternate gene names: 189352994

Gene position: 1158155-1156827 (Counterclockwise)

Preceding gene: 189352995

Following gene: 189352989

Centisome position: 46.83

GC content: 68.62

Gene sequence:

>1329_bases
ATGTCCACTCATCACGCTCAGGCCCTGCCGTCCGCCGCGCAAGATGCAAGCGCGTCGCTGAACCGGCTGCTGTTCCGCAA
ACTGATGCCGCTGCTGATCGCCGCCTATGTCATCAGCTTTCTCGATCGCACCAACATCGCCTTCGCGAAGCATTCGATGG
GCGTCGATCTCGGCATCTCGTCCGCCGCCTACGGCCTCGGCGCCGGACTGTTCTTCCTGACTTACGCGCTATTCGAAATC
CCGAGCAACCTGATCATGCACCGCGTCGGCGCGCGCTTCTGGATCACGCGGATCATGATCACGTGGGGCGCACTGTCGGT
TGCGATGGCGTTCGTGCGCGGCGAAACATCGTTCTACGTCATGCGGCTGCTGCTCGGCGCAGCCGAAGCCGGGCTCTTTC
CCGGCGTGATGCTCTATCTGACGTACTGGTTCGGCCGCGAACAGCGCGCGCGCGCGACCGGCTATTTCCTACTCGGCGTA
TGCATCGCGAACGTGGTCGGCGGCCCGCTGGCCGGCGCGCTGATCGAACTCGACGGCACGCTGGGCTTTCACGGCTGGCA
ATGGCTGTTCGTCGTCGAAGGGATTCCGGCGATCCTGCTCGCGTTCGTCGTGTGGACACGGCTGCCGGACCGTCCGAGCA
CCGCGCCGTGGCTCGCGCCGGACACGGGCCGTGCGCTCGAGCGCGCGCTCGCCGCGGAACAGGACGCCGGTGCCGCCTCG
CACGGCGGCCATGCATTCGGTGCCGCGCTGCGCGACCCGCAGATCTGGCTCGCGATCTTCGTCTACTTCTGTCATCAACT
GACGATCTACACGGTGATCTTTTTTCTGCCGGCGATCATCGGCGCATCGGGCCGGCTGTCGCCGATCGCGGTCGGCCTGC
TCACCGCGCTGCCGTGGCTGGCCGCCGCGCTCGGCGCCGCGACGCTGCCGCGCTTCGCGCGCGAATCGCGGCATTCGCGC
GCGCTGCTGTGCGCGGGCCTCGTCGTGATGGCGGCCGGCATGGTCGGCGCCGCGCACGCGTCGCCGCTCGCGGGACTGCT
ATGCGTGTGCGTCGCCGCGTCGATGTTCTTCGTCGTCCAGTCGATCGTATTTACGTTTCCCGCCTCGCGGCTGGCCGGCA
GCGCGCTCGCGGGCGGCCTCGGCCTCGTCAACACCTGCGGCCTGCTCGGCGGCTTCGTCGGCCCGACCGTCGTCGGCGCA
ATCGAACAGGCGACCGGCGATGCGAAGAACGGCCTGACGCTGCTGGCGGCCGCACTCGTCGTCGCGGCGCTCGCGAGCCT
GGCGCTGCGTCACGGACACGAACGGCAGCGCGCGCGTTCTGCCGCATGA

Upstream 100 bases:

>100_bases
GTCGTCTGCTCGTTCGCCGCGCCCCGCGCGGCGGCCTCTGTCGAACGCGGCACGTCGTGCTTGCCGTGCGCGCCGGTTCG
CCCTTAACGGAGTCGTCCGC

Downstream 100 bases:

>100_bases
CGGGTGCAGCTCGGGCCGGCGCGCGCGAGAGCCGACGCTCGCCCGCGCGCACCGGCCGTTCGGAACGCGCTCAGAACAGA
TACATCCCCGCGACGAACAC

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSTHHAQALPSAAQDASASLNRLLFRKLMPLLIAAYVISFLDRTNIAFAKHSMGVDLGISSAAYGLGAGLFFLTYALFEI
PSNLIMHRVGARFWITRIMITWGALSVAMAFVRGETSFYVMRLLLGAAEAGLFPGVMLYLTYWFGREQRARATGYFLLGV
CIANVVGGPLAGALIELDGTLGFHGWQWLFVVEGIPAILLAFVVWTRLPDRPSTAPWLAPDTGRALERALAAEQDAGAAS
HGGHAFGAALRDPQIWLAIFVYFCHQLTIYTVIFFLPAIIGASGRLSPIAVGLLTALPWLAAALGAATLPRFARESRHSR
ALLCAGLVVMAAGMVGAAHASPLAGLLCVCVAASMFFVVQSIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGA
IEQATGDAKNGLTLLAAALVVAALASLALRHGHERQRARSAA

Sequences:

>Translated_442_residues
MSTHHAQALPSAAQDASASLNRLLFRKLMPLLIAAYVISFLDRTNIAFAKHSMGVDLGISSAAYGLGAGLFFLTYALFEI
PSNLIMHRVGARFWITRIMITWGALSVAMAFVRGETSFYVMRLLLGAAEAGLFPGVMLYLTYWFGREQRARATGYFLLGV
CIANVVGGPLAGALIELDGTLGFHGWQWLFVVEGIPAILLAFVVWTRLPDRPSTAPWLAPDTGRALERALAAEQDAGAAS
HGGHAFGAALRDPQIWLAIFVYFCHQLTIYTVIFFLPAIIGASGRLSPIAVGLLTALPWLAAALGAATLPRFARESRHSR
ALLCAGLVVMAAGMVGAAHASPLAGLLCVCVAASMFFVVQSIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGA
IEQATGDAKNGLTLLAAALVVAALASLALRHGHERQRARSAA
>Mature_441_residues
STHHAQALPSAAQDASASLNRLLFRKLMPLLIAAYVISFLDRTNIAFAKHSMGVDLGISSAAYGLGAGLFFLTYALFEIP
SNLIMHRVGARFWITRIMITWGALSVAMAFVRGETSFYVMRLLLGAAEAGLFPGVMLYLTYWFGREQRARATGYFLLGVC
IANVVGGPLAGALIELDGTLGFHGWQWLFVVEGIPAILLAFVVWTRLPDRPSTAPWLAPDTGRALERALAAEQDAGAASH
GGHAFGAALRDPQIWLAIFVYFCHQLTIYTVIFFLPAIIGASGRLSPIAVGLLTALPWLAAALGAATLPRFARESRHSRA
LLCAGLVVMAAGMVGAAHASPLAGLLCVCVAASMFFVVQSIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGAI
EQATGDAKNGLTLLAAALVVAALASLALRHGHERQRARSAA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=426, Percent_Identity=38.7323943661972, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI87082320, Length=437, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI2367379, Length=296, Percent_Identity=23.3108108108108, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789515, Length=275, Percent_Identity=22.9090909090909, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789152, Length=477, Percent_Identity=20.7547169811321, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569727, Length=182, Percent_Identity=25.8241758241758, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=246, Percent_Identity=23.1707317073171, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=246, Percent_Identity=23.1707317073171, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=316, Percent_Identity=24.6835443037975, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322025, Length=180, Percent_Identity=30.5555555555556, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322612, Length=236, Percent_Identity=25, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=265, Percent_Identity=22.2641509433962, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319876, Length=241, Percent_Identity=21.9917012448133, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46499; Mature: 46368

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHHAQALPSAAQDASASLNRLLFRKLMPLLIAAYVISFLDRTNIAFAKHSMGVDLGIS
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCH
SAAYGLGAGLFFLTYALFEIPSNLIMHRVGARFWITRIMITWGALSVAMAFVRGETSFYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MRLLLGAAEAGLFPGVMLYLTYWFGREQRARATGYFLLGVCIANVVGGPLAGALIELDGT
HHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCC
LGFHGWQWLFVVEGIPAILLAFVVWTRLPDRPSTAPWLAPDTGRALERALAAEQDAGAAS
CCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
HGGHAFGAALRDPQIWLAIFVYFCHQLTIYTVIFFLPAIIGASGRLSPIAVGLLTALPWL
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAALGAATLPRFARESRHSRALLCAGLVVMAAGMVGAAHASPLAGLLCVCVAASMFFVVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGAIEQATGDAKNGLTLLAAALV
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VAALASLALRHGHERQRARSAA
HHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure 
STHHAQALPSAAQDASASLNRLLFRKLMPLLIAAYVISFLDRTNIAFAKHSMGVDLGIS
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCH
SAAYGLGAGLFFLTYALFEIPSNLIMHRVGARFWITRIMITWGALSVAMAFVRGETSFYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MRLLLGAAEAGLFPGVMLYLTYWFGREQRARATGYFLLGVCIANVVGGPLAGALIELDGT
HHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCC
LGFHGWQWLFVVEGIPAILLAFVVWTRLPDRPSTAPWLAPDTGRALERALAAEQDAGAAS
CCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
HGGHAFGAALRDPQIWLAIFVYFCHQLTIYTVIFFLPAIIGASGRLSPIAVGLLTALPWL
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAALGAATLPRFARESRHSRALLCAGLVVMAAGMVGAAHASPLAGLLCVCVAASMFFVVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGAIEQATGDAKNGLTLLAAALV
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VAALASLALRHGHERQRARSAA
HHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]