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The map label for this gene is clcB [H]

Identifier: 189352992

GI number: 189352992

Start: 1153896

End: 1155242

Strand: Direct

Name: clcB [H]

Synonym: BMULJ_04226

Alternate gene names: 189352992

Gene position: 1153896-1155242 (Clockwise)

Preceding gene: 189352991

Following gene: 189352993

Centisome position: 46.66

GC content: 72.01

Gene sequence:

>1347_bases
ATGCGCGCCGATCTGCCGTCCGCTCCGTCCTCATCGTCCTCGTCCTCCGCGCCCGCCGTGAGCCCGTTCGCGCGGATCGC
GGCCGTCACGATCGTCACGGGCATCGGCGCGGGCCTCGGCGGCATGCTGCTCGCGCTGCTGCTGCACGCGATCCAGCATC
TCGCGTACGGCTATGGCGCCGCGCATCTGGTTGGCACCGAAAGCTTTCTCATCGGCGTGACGGATGCCGATCCGCTGCGT
CGCGTCGCGGCGATGATCGTCTGCGGCATCGTCGCGGGCGGCGGCTGGTGGGCGCTTTACCGCTACGGGCAGCCGCTCGT
CGGCATTCGTCGCGCGGTGCAGGCCGCCGACCCGCGGATGCCGTTGGTCAGCACCACGATGCATGCGCTGCTGCAGATCG
TCACCGTCGCGCTCGGCTCGCCGCTCGGCCGCGAAGTCGCGCCGCGCGAGATCGGCGCACTGATCGCGGGCCGGCTCGCG
CATCGCGCGGGGCTGAGGTGCGACGATTGCCGCTTGATGGTCGCGTGCGGCGCCGGTGCAGGCCTCGCGGCCGTGTACAA
CGTGCCGCTCGGCGGCGCGGTGTTCGTGCTCGAGGTGTTGCTCGGCACGTTCGCCGCGCGCGCGGTGGCCGTCGCGCTCG
TCACGTCGACGATCGCCGCCGTCGTCGCGTGGATCGGGCTCGGCAACGAACACCAGTACACGATCGCGCCGTTCGTGCCG
AGTGCGCCGCTCGTCGCCTGGTCGATCGTCTGCGGACCGCTGTTCGGCTTCGCCGCCTACGGTTTCGTGCGGCTCACGAC
GCGGGCGCGCGCCGATGCGCCGAAGGACATACGGCTGCCGATTCTCTCGCTCGTCAATTTCGCGGCGATCGGCGTGCTCG
CGATGCGCTTTCCGTCATTGCTCGGCAACGGCAAGGGGCCCGCATCGCTCGGCTTCGACGGCACGCTGACGATCGGCATC
GCCGCGACGCTGCTCGTGCTGAAGGTCGCGATCGAAGCGGCCAGCCTGCGCGCCGGTGCCGAAGGCGGCCTGCTGACGCC
GGGCCTCGCCAACGGCGCGCTGCTCGGCGTCGTGCTCGGCGGGCTGTGGAGCGCCGTCTGGCCCGGCGCGTCGCTGGGCG
GCTGCGCGCTCGTCGGCGCGACCGCATTCCTGGCCGCGTCGATGCAGATGCCGATCACGGCCGTCGTGCTGCTGCTCGAG
TTCACGCGCGCGAATCACGACAGCCTCGTGCCGATGCTGCTCGCGGTGGCCGGTTCGCTCGTCGCATACCGGTTTGCGCA
GCAGCGTGCCGAACGGCGCGCGACGACACGCGCCACGCTCGTCACGCGCGCGACCGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
AAAAATACGTTTGTCTCATGGTGGGCGCGCGCCTACGATTCGGTGCTGACGACGGCGCGCGCGGTGCGCGCCGTGTCGAT
CCCCTCCGGTCACCGAACTC

Downstream 100 bases:

>100_bases
CGCGCTGATGCGCGTTCGCGCGATACGGTCGCGGCGGCACGCTCCGCCGCTTGGCGCCTGCCTCGTTTCCCGTTCACGCC
GGTTCGCACGTCGAAGCGCA

Product: putative chloride channel protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRADLPSAPSSSSSSSAPAVSPFARIAAVTIVTGIGAGLGGMLLALLLHAIQHLAYGYGAAHLVGTESFLIGVTDADPLR
RVAAMIVCGIVAGGGWWALYRYGQPLVGIRRAVQAADPRMPLVSTTMHALLQIVTVALGSPLGREVAPREIGALIAGRLA
HRAGLRCDDCRLMVACGAGAGLAAVYNVPLGGAVFVLEVLLGTFAARAVAVALVTSTIAAVVAWIGLGNEHQYTIAPFVP
SAPLVAWSIVCGPLFGFAAYGFVRLTTRARADAPKDIRLPILSLVNFAAIGVLAMRFPSLLGNGKGPASLGFDGTLTIGI
AATLLVLKVAIEAASLRAGAEGGLLTPGLANGALLGVVLGGLWSAVWPGASLGGCALVGATAFLAASMQMPITAVVLLLE
FTRANHDSLVPMLLAVAGSLVAYRFAQQRAERRATTRATLVTRATAAR

Sequences:

>Translated_448_residues
MRADLPSAPSSSSSSSAPAVSPFARIAAVTIVTGIGAGLGGMLLALLLHAIQHLAYGYGAAHLVGTESFLIGVTDADPLR
RVAAMIVCGIVAGGGWWALYRYGQPLVGIRRAVQAADPRMPLVSTTMHALLQIVTVALGSPLGREVAPREIGALIAGRLA
HRAGLRCDDCRLMVACGAGAGLAAVYNVPLGGAVFVLEVLLGTFAARAVAVALVTSTIAAVVAWIGLGNEHQYTIAPFVP
SAPLVAWSIVCGPLFGFAAYGFVRLTTRARADAPKDIRLPILSLVNFAAIGVLAMRFPSLLGNGKGPASLGFDGTLTIGI
AATLLVLKVAIEAASLRAGAEGGLLTPGLANGALLGVVLGGLWSAVWPGASLGGCALVGATAFLAASMQMPITAVVLLLE
FTRANHDSLVPMLLAVAGSLVAYRFAQQRAERRATTRATLVTRATAAR
>Mature_448_residues
MRADLPSAPSSSSSSSAPAVSPFARIAAVTIVTGIGAGLGGMLLALLLHAIQHLAYGYGAAHLVGTESFLIGVTDADPLR
RVAAMIVCGIVAGGGWWALYRYGQPLVGIRRAVQAADPRMPLVSTTMHALLQIVTVALGSPLGREVAPREIGALIAGRLA
HRAGLRCDDCRLMVACGAGAGLAAVYNVPLGGAVFVLEVLLGTFAARAVAVALVTSTIAAVVAWIGLGNEHQYTIAPFVP
SAPLVAWSIVCGPLFGFAAYGFVRLTTRARADAPKDIRLPILSLVNFAAIGVLAMRFPSLLGNGKGPASLGFDGTLTIGI
AATLLVLKVAIEAASLRAGAEGGLLTPGLANGALLGVVLGGLWSAVWPGASLGGCALVGATAFLAASMQMPITAVVLLLE
FTRANHDSLVPMLLAVAGSLVAYRFAQQRAERRATTRATLVTRATAAR

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 45686; Mature: 45686

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADLPSAPSSSSSSSAPAVSPFARIAAVTIVTGIGAGLGGMLLALLLHAIQHLAYGYGA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
AHLVGTESFLIGVTDADPLRRVAAMIVCGIVAGGGWWALYRYGQPLVGIRRAVQAADPRM
HHEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCC
PLVSTTMHALLQIVTVALGSPLGREVAPREIGALIAGRLAHRAGLRCDDCRLMVACGAGA
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
GLAAVYNVPLGGAVFVLEVLLGTFAARAVAVALVTSTIAAVVAWIGLGNEHQYTIAPFVP
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
SAPLVAWSIVCGPLFGFAAYGFVRLTTRARADAPKDIRLPILSLVNFAAIGVLAMRFPSL
CCHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGNGKGPASLGFDGTLTIGIAATLLVLKVAIEAASLRAGAEGGLLTPGLANGALLGVVLG
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
GLWSAVWPGASLGGCALVGATAFLAASMQMPITAVVLLLEFTRANHDSLVPMLLAVAGSL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VAYRFAQQRAERRATTRATLVTRATAAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRADLPSAPSSSSSSSAPAVSPFARIAAVTIVTGIGAGLGGMLLALLLHAIQHLAYGYGA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
AHLVGTESFLIGVTDADPLRRVAAMIVCGIVAGGGWWALYRYGQPLVGIRRAVQAADPRM
HHEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCC
PLVSTTMHALLQIVTVALGSPLGREVAPREIGALIAGRLAHRAGLRCDDCRLMVACGAGA
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
GLAAVYNVPLGGAVFVLEVLLGTFAARAVAVALVTSTIAAVVAWIGLGNEHQYTIAPFVP
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
SAPLVAWSIVCGPLFGFAAYGFVRLTTRARADAPKDIRLPILSLVNFAAIGVLAMRFPSL
CCHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGNGKGPASLGFDGTLTIGIAATLLVLKVAIEAASLRAGAEGGLLTPGLANGALLGVVLG
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
GLWSAVWPGASLGGCALVGATAFLAASMQMPITAVVLLLEFTRANHDSLVPMLLAVAGSL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VAYRFAQQRAERRATTRATLVTRATAAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA