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The map label for this gene is namA [H]

Identifier: 189352950

GI number: 189352950

Start: 1105896

End: 1107005

Strand: Direct

Name: namA [H]

Synonym: BMULJ_04184

Alternate gene names: 189352950

Gene position: 1105896-1107005 (Clockwise)

Preceding gene: 189352949

Following gene: 189352951

Centisome position: 44.72

GC content: 69.64

Gene sequence:

>1110_bases
ATGTCTGCCTTGTTCGAACCGTTCAAACTGAAGGATGTCACGTTGCGCAACCGGATCGCGGTGCCGCCGATGTGTCAGTA
CGTCGCCGAGGACGGCGTCGTCAACGACTGGCATCACGTGCACCTGGCCGGCATCGCCCGCGGCGGCGCGGGCCTCGTGA
TCGCCGAGGCGACGGCCGTGTCGCCGGAAGGCCGCATCACGCCGGGCTGCGCCGGACTCTGGACCGATGCGCAGGCCGAA
GCGTTCGCGCCGTCGGTCGCGGCGATCAAGGCCGCGGGCGCGGTGCCCGGCATCCAGATCGCGCATGCGGGCCGCAAGGC
GAGCGCGAACCGTCCGTGGGAAGGCGACGACCATATCCCCGAAGGCGATCCGCGCGGCTGGCAGACGATTGCGCCGTCGG
CCGTGCCGTTCGGCGCGCATCTGCCGAAGGTACCGCGCGAGATGACGCGCGACGACATCGCACGCGTGCAGGCCGATTTC
GTCGCGGCGGCCAAGCGTGCGCGCGACATCGGCTTCGAATGGCTCGAACTGCATTTCGCACACGGCTACCTCGGCCAGAG
CTTCTTCTCCGTGCACTCGAACCGGCGCACCGACGAATACGGCGGCTCGGCCGAGAATCGCGGCCGCTTCCTCGTCGAGA
CGCTGGCCGCGGTCCGCAAGGTCTGGCCCGAGCATCTGCCGCTGACCGTGCGTTTCGGCGTCATCGAATACGACGGCCGC
GATGAGGAGACGCTCGCCGAATCGATCGCGCTCACGCAGCGGCTGAAGCAGGAAGGGCTCGACATGCTGAGCGTGTCGGT
CGGCTTCTCGACGCCCGATGCGCAGATTCCGTGGGGCCCGGCGTTCCTCGCGCCGGTCGCCGAGCGTGTGCGCCGCGAAG
CGGGGCTGCCGGTGTCGTCCGCGTGGGGCATCGACACGCCGCAACTGGCGAACCGCGTCGTCGCCGACGAGCAGCTCGAT
CTCGTGATGGTCGGCCGCGCGCATCTGGCCGACCCGCACTGGCCGTACTATGCGGCCAAGCAGCTCGGCGTCGAGCGTCC
GTCGTGGACGCTGCCCGCGCCGTATGCCCACTGGCTCGAGCGCTATCGCGTCGCCGAGAAGGCAGCGTAA

Upstream 100 bases:

>100_bases
GCGTCGCGCAAGCGGCGCGCCGGCATCCGTTTCGCGCCGTCGTGCAGCCGCATGACGGCTCAACCCGCCGTTTCGCAGGA
CCAAGCAAAAGGAGTCGTGG

Downstream 100 bases:

>100_bases
GCCCGCGTCGCGCCGCGCCCATGCGCGGCTTCGATGGATAGAATGGCGGTTCGCGCAGTGAGGTTGCTGCGCGAACCGCC
ATTTTTTTCTTTCGACAGAG

Product: NADPH2 dehydrogenase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSALFEPFKLKDVTLRNRIAVPPMCQYVAEDGVVNDWHHVHLAGIARGGAGLVIAEATAVSPEGRITPGCAGLWTDAQAE
AFAPSVAAIKAAGAVPGIQIAHAGRKASANRPWEGDDHIPEGDPRGWQTIAPSAVPFGAHLPKVPREMTRDDIARVQADF
VAAAKRARDIGFEWLELHFAHGYLGQSFFSVHSNRRTDEYGGSAENRGRFLVETLAAVRKVWPEHLPLTVRFGVIEYDGR
DEETLAESIALTQRLKQEGLDMLSVSVGFSTPDAQIPWGPAFLAPVAERVRREAGLPVSSAWGIDTPQLANRVVADEQLD
LVMVGRAHLADPHWPYYAAKQLGVERPSWTLPAPYAHWLERYRVAEKAA

Sequences:

>Translated_369_residues
MSALFEPFKLKDVTLRNRIAVPPMCQYVAEDGVVNDWHHVHLAGIARGGAGLVIAEATAVSPEGRITPGCAGLWTDAQAE
AFAPSVAAIKAAGAVPGIQIAHAGRKASANRPWEGDDHIPEGDPRGWQTIAPSAVPFGAHLPKVPREMTRDDIARVQADF
VAAAKRARDIGFEWLELHFAHGYLGQSFFSVHSNRRTDEYGGSAENRGRFLVETLAAVRKVWPEHLPLTVRFGVIEYDGR
DEETLAESIALTQRLKQEGLDMLSVSVGFSTPDAQIPWGPAFLAPVAERVRREAGLPVSSAWGIDTPQLANRVVADEQLD
LVMVGRAHLADPHWPYYAAKQLGVERPSWTLPAPYAHWLERYRVAEKAA
>Mature_368_residues
SALFEPFKLKDVTLRNRIAVPPMCQYVAEDGVVNDWHHVHLAGIARGGAGLVIAEATAVSPEGRITPGCAGLWTDAQAEA
FAPSVAAIKAAGAVPGIQIAHAGRKASANRPWEGDDHIPEGDPRGWQTIAPSAVPFGAHLPKVPREMTRDDIARVQADFV
AAAKRARDIGFEWLELHFAHGYLGQSFFSVHSNRRTDEYGGSAENRGRFLVETLAAVRKVWPEHLPLTVRFGVIEYDGRD
EETLAESIALTQRLKQEGLDMLSVSVGFSTPDAQIPWGPAFLAPVAERVRREAGLPVSSAWGIDTPQLANRVVADEQLDL
VMVGRAHLADPHWPYYAAKQLGVERPSWTLPAPYAHWLERYRVAEKAA

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=352, Percent_Identity=28.4090909090909, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789463, Length=336, Percent_Identity=26.1904761904762, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=259, Percent_Identity=28.957528957529, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17559802, Length=258, Percent_Identity=28.2945736434109, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540738, Length=256, Percent_Identity=28.90625, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=259, Percent_Identity=26.2548262548263, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=264, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=263, Percent_Identity=26.9961977186312, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17566914, Length=324, Percent_Identity=26.2345679012346, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=238, Percent_Identity=28.9915966386555, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=240, Percent_Identity=28.75, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40328; Mature: 40197

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFEPFKLKDVTLRNRIAVPPMCQYVAEDGVVNDWHHVHLAGIARGGAGLVIAEATAV
CCCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEE
SPEGRITPGCAGLWTDAQAEAFAPSVAAIKAAGAVPGIQIAHAGRKASANRPWEGDDHIP
CCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCC
EGDPRGWQTIAPSAVPFGAHLPKVPREMTRDDIARVQADFVAAAKRARDIGFEWLELHFA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HGYLGQSFFSVHSNRRTDEYGGSAENRGRFLVETLAAVRKVWPEHLPLTVRFGVIEYDGR
HHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCHHHCCEEEEEEEEEECCC
DEETLAESIALTQRLKQEGLDMLSVSVGFSTPDAQIPWGPAFLAPVAERVRREAGLPVSS
CHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
AWGIDTPQLANRVVADEQLDLVMVGRAHLADPHWPYYAAKQLGVERPSWTLPAPYAHWLE
CCCCCCHHHHHHHHCCCCCCEEEECHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
RYRVAEKAA
HHHHHHHCC
>Mature Secondary Structure 
SALFEPFKLKDVTLRNRIAVPPMCQYVAEDGVVNDWHHVHLAGIARGGAGLVIAEATAV
CCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEE
SPEGRITPGCAGLWTDAQAEAFAPSVAAIKAAGAVPGIQIAHAGRKASANRPWEGDDHIP
CCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCC
EGDPRGWQTIAPSAVPFGAHLPKVPREMTRDDIARVQADFVAAAKRARDIGFEWLELHFA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HGYLGQSFFSVHSNRRTDEYGGSAENRGRFLVETLAAVRKVWPEHLPLTVRFGVIEYDGR
HHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCHHHCCEEEEEEEEEECCC
DEETLAESIALTQRLKQEGLDMLSVSVGFSTPDAQIPWGPAFLAPVAERVRREAGLPVSS
CHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
AWGIDTPQLANRVVADEQLDLVMVGRAHLADPHWPYYAAKQLGVERPSWTLPAPYAHWLE
CCCCCCHHHHHHHHCCCCCCEEEECHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
RYRVAEKAA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA