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The map label for this gene is baeR [H]

Identifier: 189352919

GI number: 189352919

Start: 1068541

End: 1069278

Strand: Reverse

Name: baeR [H]

Synonym: BMULJ_04153

Alternate gene names: 189352919

Gene position: 1069278-1068541 (Counterclockwise)

Preceding gene: 189352920

Following gene: 189352918

Centisome position: 43.24

GC content: 67.89

Gene sequence:

>738_bases
ATGCCCGACATGTCTTCCTTTTCCGGCGCCGGCCAGCGTGCCCAGGCGCTCGTCCTCATTGCCGAGGACGAACCCGAGAT
CGCGGAAATCCTGACCGCCTATTTTGCGCGCAGCGGCCTGCGCACCGTGCACGCGGCCGACGGCCGCCGTGCGCTCGAAC
TCCACCTGTCGATCAAGCCCGACCTCGTGCTGCTCGACGTGCAGATGCCGCAAATCGACGGCTGGAAGGTGCTCGCGGAG
ATTCGCCATCGCGGCGACACGCCCGTCATCATGCTGACCGCGCTCGACCAGGACGTCGACAAGCTCACCGGTCTGCGCAT
CGGCGCCGACGACTACGTGGTCAAGCCCTTCAATCCGGCCGAAGTCGTCGCGCGCGCGCAGGCCGTGCTGCGTCGCTCGA
TGGCCGCTTCGCGCGACGATGCGCAGCCGGTGCTGCGCGCCGCGCCGTTCGAGATCGACCTCGAACGCCATGAGGCAACG
GTGGAGATCGACGGCACGCGCCATACGCTTGTGCTGACGCTCACCGAATTCAAGCTGCTCGCGCAACTGGCGCGCGCACC
GCGCCGCGTGTTCACGCGCGCCGAACTGATGGCGACCTGCCTGCCGGAGGGCGATGCGCTGGAGCGCACGGTCGACAGCC
ACGTCAGCAAGCTGCGCAAGAAGCTGGACGATCTCGGTATTGGGGGCGTGCCGGTCAGCGTGCGCGGGGTCGGCTACAAG
CTGTGGAGCGGCGAATGA

Upstream 100 bases:

>100_bases
CCCGCCCGCGCATTCGATGCGCTCCGGCTCGAATCGAACGAACGAGCCGTGCGGTAGTATGGCGGCTCAATGAAACACCG
ACGGATCCGAGCGAGCCGCC

Downstream 100 bases:

>100_bases
AGCTCGACGGGCTGAGCCGCCAGATCGCGCTGACGATGGGCGCGGTCGTGTTCGGCGTCACGCTGCTGCTCGTGCTGACG
GCCTACGTGTTCTATTACCT

Product: signal transduction response regulator

Products: NA

Alternate protein names: Staphylococcal respiratory response protein A [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MPDMSSFSGAGQRAQALVLIAEDEPEIAEILTAYFARSGLRTVHAADGRRALELHLSIKPDLVLLDVQMPQIDGWKVLAE
IRHRGDTPVIMLTALDQDVDKLTGLRIGADDYVVKPFNPAEVVARAQAVLRRSMAASRDDAQPVLRAAPFEIDLERHEAT
VEIDGTRHTLVLTLTEFKLLAQLARAPRRVFTRAELMATCLPEGDALERTVDSHVSKLRKKLDDLGIGGVPVSVRGVGYK
LWSGE

Sequences:

>Translated_245_residues
MPDMSSFSGAGQRAQALVLIAEDEPEIAEILTAYFARSGLRTVHAADGRRALELHLSIKPDLVLLDVQMPQIDGWKVLAE
IRHRGDTPVIMLTALDQDVDKLTGLRIGADDYVVKPFNPAEVVARAQAVLRRSMAASRDDAQPVLRAAPFEIDLERHEAT
VEIDGTRHTLVLTLTEFKLLAQLARAPRRVFTRAELMATCLPEGDALERTVDSHVSKLRKKLDDLGIGGVPVSVRGVGYK
LWSGE
>Mature_244_residues
PDMSSFSGAGQRAQALVLIAEDEPEIAEILTAYFARSGLRTVHAADGRRALELHLSIKPDLVLLDVQMPQIDGWKVLAEI
RHRGDTPVIMLTALDQDVDKLTGLRIGADDYVVKPFNPAEVVARAQAVLRRSMAASRDDAQPVLRAAPFEIDLERHEATV
EIDGTRHTLVLTLTEFKLLAQLARAPRRVFTRAELMATCLPEGDALERTVDSHVSKLRKKLDDLGIGGVPVSVRGVGYKL
WSGE

Specific function: Member of the two-component regulatory system srrA/srrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels. SrrA binds to the agr, spa and tst promoters and represses their transcript

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=36.0869565217391, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=37.0044052863436, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=33.7719298245614, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=38.7931034482759, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=32.5991189427313, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789809, Length=214, Percent_Identity=32.2429906542056, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.4801762114537, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=28.2608695652174, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=31.7180616740088, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.4801762114537, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=30.7359307359307, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=31.858407079646, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=31.1688311688312, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=44.2477876106195, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=43, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=31.4893617021277, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=32.0610687022901, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26918; Mature: 26787

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDMSSFSGAGQRAQALVLIAEDEPEIAEILTAYFARSGLRTVHAADGRRALELHLSIKP
CCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECC
DLVLLDVQMPQIDGWKVLAEIRHRGDTPVIMLTALDQDVDKLTGLRIGADDYVVKPFNPA
CEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCEEECCCCEEECCCCHH
EVVARAQAVLRRSMAASRDDAQPVLRAAPFEIDLERHEATVEIDGTRHTLVLTLTEFKLL
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEECCEEEEEECCCCEEEEEEHHHHHHH
AQLARAPRRVFTRAELMATCLPEGDALERTVDSHVSKLRKKLDDLGIGGVPVSVRGVGYK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECEEE
LWSGE
ECCCC
>Mature Secondary Structure 
PDMSSFSGAGQRAQALVLIAEDEPEIAEILTAYFARSGLRTVHAADGRRALELHLSIKP
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECC
DLVLLDVQMPQIDGWKVLAEIRHRGDTPVIMLTALDQDVDKLTGLRIGADDYVVKPFNPA
CEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCEEECCCCEEECCCCHH
EVVARAQAVLRRSMAASRDDAQPVLRAAPFEIDLERHEATVEIDGTRHTLVLTLTEFKLL
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEECCEEEEEECCCCEEEEEEHHHHHHH
AQLARAPRRVFTRAELMATCLPEGDALERTVDSHVSKLRKKLDDLGIGGVPVSVRGVGYK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECEEE
LWSGE
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA