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The map label for this gene is 189352891

Identifier: 189352891

GI number: 189352891

Start: 1035582

End: 1037360

Strand: Direct

Name: 189352891

Synonym: BMULJ_04125

Alternate gene names: NA

Gene position: 1035582-1037360 (Clockwise)

Preceding gene: 189352890

Following gene: 189352892

Centisome position: 41.87

GC content: 64.53

Gene sequence:

>1779_bases
ATGGCCGCAGAGAAAAAGCCGCATGTCGATGCGGTGATCGTCGGCTTCGGCTGGACCGGCGCGATTCTCGCGAAGGAACT
GACCGAAGCAGGACTGAAAGTCGTCGCGCTCGAGCGCGGCGAATATCGCGACACCTATCCGGATGGCGCGTATCCGAACA
CGATCGACGAGCTGACCTACAACATCCGCAAGAAGCTGTTCCTCGACCTGTCGAAGACGACCGTGTCGATCCGCCACGGC
ATCAACGACACCGCGCTGCCGTATCGGCAGCTCGCCGCGTTTCTGCCGGGCGAGGGCGTCGGCGGCGCGGGGCTGCACTG
GTCCGGCGTGCATTTCCGCATCACGCCCGAGGAGCTGCGGCTGCGCAGCCACTATGAAGAGCGCTACGGAAAGAAGTTCA
TTCCGGAAGGGATGACGATCCAGGACACCGGCGTCAGCTACGACGAGCTCGAGCCGCATTTCGACTTCGCGGAGAAGGTG
TTCGGCACGTCGGGGCAGGCGTACAAGGTCGGCGGCAAGGTGGTCGGCGACGGCAACGTGTTCGAGGCGAACCGCAGCGA
TCATTTTCCGCTGCCGCCGCAGCTCAACACGTATTCGGCGCAGCGCTTCTACGATGCCGCGAAGTCGCTCGGGCTGCATC
CGTACCGGCTGCCGTCGGCGAACACGTCGGGCCCGTACACGAATCCGTACGGCGTGCAGATGGGGCCGTGCAACTTCTGC
GGCTACTGCAGCGGCTACGCGTGCTACATGTATTCGAAGGCGTCGCCGAACCTGAACATCCTGCCCGCGCTGAAGCAGAC
GCCGAACTTCGAGCTGCGCTCGAAGTGCCACGTGCTGCGCGTCGACCTCGACGACACGAAGAAGCGCGCGACCGGCGTCA
CCTACGTCGATCCGACCGGCCGTGAAGTGCATCAGCCGGCCGATCTCGTGATCGTCGCCGCGTTCCAGTATCACAACGTG
CATCTGCTGCTGCTGTCGGGCATCGGCAAGCCGTACGATCCGATCTCGGGCGAAGGCGTCGTGGGCCGCAATTTCGCGTA
CCAGAACCTGTCGACGATCAAGGCGTTCTTCGACCGCGATACGTTCACGAACCCGTTCGTGGGCGCCGGCGGCAACGGCG
TCGCGGTCGACGACTTCAACGCGGACAACTTCGATCACGGCCCGCTCGGCTTCGTCGGCGGCTCGCCGCTGTGGGTGAAC
CAGGCCGGCGTGAAGCCGGTGAGCGGGATCGCGGTGCCGCCGGGCACGCCGGGCTGGGGTTCCGCGTGGAAGAAGGCGGT
GAAGGATTACTACGCGCACACGATCTCGATGGACGCGCACGGCACGAACATGTCGTACCGCGACGTCTATCTCGATCTCG
ATCCGACCTATCGCGATTCGTACGGGCAGCCGCTGCTGCGCATGACCTTCGACTGGAAGGACAACGACATCCGGATGGCG
CAGTACGTGACAGGCCAGATGAAGAAGATCGCGGAAGCGATGGGGCCGAAGGCGATCGGCGTGTCGACGCGCGAGTTCGG
CAAGCACTTCGATACGCGTGCGTACCAGACGACGCACCTGGTCGGCGGCGCCGTGATGGGCACCGATCCGAAGACGAGCG
TGCTGAACCGCTATCTGCAGTGCTGGGACGTGCACAACGTGTTCGTGATGGGCGCGTCGGCGCTGCCGCAGGGCATCGGC
TACAACCCGACCGGCATCGTCGCGGCGCTCGCGTACTGGTCGGCGCGCGCGATCCGTGAGCAATACCTGAAAAATCCCGC
TCCGCTGGTGACCGTATGA

Upstream 100 bases:

>100_bases
TCGGCTTTCCGGGCGCGCGCGCCGATTTCATGGATTTCGTCAACCAGAACGGCAAGCCGTATCCGTACGGCCCCGTGTCG
ATCAACGGGGAGCGTAGCTG

Downstream 100 bases:

>100_bases
AGAGGATCGTGACCCACCGTATCGCGCGCCGCCTGTCGCGCGCATTGGCCGCGAGCGCTGCATGCGTGGCGCTCGGCTTC
GGCAGCGCGGCGGCGCTCGC

Product: gluconate 2-dehydrogenase alpha chain

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MAAEKKPHVDAVIVGFGWTGAILAKELTEAGLKVVALERGEYRDTYPDGAYPNTIDELTYNIRKKLFLDLSKTTVSIRHG
INDTALPYRQLAAFLPGEGVGGAGLHWSGVHFRITPEELRLRSHYEERYGKKFIPEGMTIQDTGVSYDELEPHFDFAEKV
FGTSGQAYKVGGKVVGDGNVFEANRSDHFPLPPQLNTYSAQRFYDAAKSLGLHPYRLPSANTSGPYTNPYGVQMGPCNFC
GYCSGYACYMYSKASPNLNILPALKQTPNFELRSKCHVLRVDLDDTKKRATGVTYVDPTGREVHQPADLVIVAAFQYHNV
HLLLLSGIGKPYDPISGEGVVGRNFAYQNLSTIKAFFDRDTFTNPFVGAGGNGVAVDDFNADNFDHGPLGFVGGSPLWVN
QAGVKPVSGIAVPPGTPGWGSAWKKAVKDYYAHTISMDAHGTNMSYRDVYLDLDPTYRDSYGQPLLRMTFDWKDNDIRMA
QYVTGQMKKIAEAMGPKAIGVSTREFGKHFDTRAYQTTHLVGGAVMGTDPKTSVLNRYLQCWDVHNVFVMGASALPQGIG
YNPTGIVAALAYWSARAIREQYLKNPAPLVTV

Sequences:

>Translated_592_residues
MAAEKKPHVDAVIVGFGWTGAILAKELTEAGLKVVALERGEYRDTYPDGAYPNTIDELTYNIRKKLFLDLSKTTVSIRHG
INDTALPYRQLAAFLPGEGVGGAGLHWSGVHFRITPEELRLRSHYEERYGKKFIPEGMTIQDTGVSYDELEPHFDFAEKV
FGTSGQAYKVGGKVVGDGNVFEANRSDHFPLPPQLNTYSAQRFYDAAKSLGLHPYRLPSANTSGPYTNPYGVQMGPCNFC
GYCSGYACYMYSKASPNLNILPALKQTPNFELRSKCHVLRVDLDDTKKRATGVTYVDPTGREVHQPADLVIVAAFQYHNV
HLLLLSGIGKPYDPISGEGVVGRNFAYQNLSTIKAFFDRDTFTNPFVGAGGNGVAVDDFNADNFDHGPLGFVGGSPLWVN
QAGVKPVSGIAVPPGTPGWGSAWKKAVKDYYAHTISMDAHGTNMSYRDVYLDLDPTYRDSYGQPLLRMTFDWKDNDIRMA
QYVTGQMKKIAEAMGPKAIGVSTREFGKHFDTRAYQTTHLVGGAVMGTDPKTSVLNRYLQCWDVHNVFVMGASALPQGIG
YNPTGIVAALAYWSARAIREQYLKNPAPLVTV
>Mature_591_residues
AAEKKPHVDAVIVGFGWTGAILAKELTEAGLKVVALERGEYRDTYPDGAYPNTIDELTYNIRKKLFLDLSKTTVSIRHGI
NDTALPYRQLAAFLPGEGVGGAGLHWSGVHFRITPEELRLRSHYEERYGKKFIPEGMTIQDTGVSYDELEPHFDFAEKVF
GTSGQAYKVGGKVVGDGNVFEANRSDHFPLPPQLNTYSAQRFYDAAKSLGLHPYRLPSANTSGPYTNPYGVQMGPCNFCG
YCSGYACYMYSKASPNLNILPALKQTPNFELRSKCHVLRVDLDDTKKRATGVTYVDPTGREVHQPADLVIVAAFQYHNVH
LLLLSGIGKPYDPISGEGVVGRNFAYQNLSTIKAFFDRDTFTNPFVGAGGNGVAVDDFNADNFDHGPLGFVGGSPLWVNQ
AGVKPVSGIAVPPGTPGWGSAWKKAVKDYYAHTISMDAHGTNMSYRDVYLDLDPTYRDSYGQPLLRMTFDWKDNDIRMAQ
YVTGQMKKIAEAMGPKAIGVSTREFGKHFDTRAYQTTHLVGGAVMGTDPKTSVLNRYLQCWDVHNVFVMGASALPQGIGY
NPTGIVAALAYWSARAIREQYLKNPAPLVTV

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 65108; Mature: 64977

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAEKKPHVDAVIVGFGWTGAILAKELTEAGLKVVALERGEYRDTYPDGAYPNTIDELTY
CCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHH
NIRKKLFLDLSKTTVSIRHGINDTALPYRQLAAFLPGEGVGGAGLHWSGVHFRITPEELR
HHHHHHHEEHHHHEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCEEECCEEEEECHHHHH
LRSHYEERYGKKFIPEGMTIQDTGVSYDELEPHFDFAEKVFGTSGQAYKVGGKVVGDGNV
HHHHHHHHHCCCCCCCCCEEEECCCCHHHCCCCHHHHHHHHCCCCCEEEECCEEEECCCE
FEANRSDHFPLPPQLNTYSAQRFYDAAKSLGLHPYRLPSANTSGPYTNPYGVQMGPCNFC
EECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCEECCCCCC
GYCSGYACYMYSKASPNLNILPALKQTPNFELRSKCHVLRVDLDDTKKRATGVTYVDPTG
CCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHCCCEEECCCC
REVHQPADLVIVAAFQYHNVHLLLLSGIGKPYDPISGEGVVGRNFAYQNLSTIKAFFDRD
CCCCCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCC
TFTNPFVGAGGNGVAVDDFNADNFDHGPLGFVGGSPLWVNQAGVKPVSGIAVPPGTPGWG
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCCCH
SAWKKAVKDYYAHTISMDAHGTNMSYRDVYLDLDPTYRDSYGQPLLRMTFDWKDNDIRMA
HHHHHHHHHHHHHEEEECCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEHH
QYVTGQMKKIAEAMGPKAIGVSTREFGKHFDTRAYQTTHLVGGAVMGTDPKTSVLNRYLQ
HHHHHHHHHHHHHHCCCEECCCHHHHHHHHCCCCEEEHEEECCEEECCCCHHHHHHHHHH
CWDVHNVFVMGASALPQGIGYNPTGIVAALAYWSARAIREQYLKNPAPLVTV
HHCCCEEEEEECHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
>Mature Secondary Structure 
AAEKKPHVDAVIVGFGWTGAILAKELTEAGLKVVALERGEYRDTYPDGAYPNTIDELTY
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHH
NIRKKLFLDLSKTTVSIRHGINDTALPYRQLAAFLPGEGVGGAGLHWSGVHFRITPEELR
HHHHHHHEEHHHHEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCEEECCEEEEECHHHHH
LRSHYEERYGKKFIPEGMTIQDTGVSYDELEPHFDFAEKVFGTSGQAYKVGGKVVGDGNV
HHHHHHHHHCCCCCCCCCEEEECCCCHHHCCCCHHHHHHHHCCCCCEEEECCEEEECCCE
FEANRSDHFPLPPQLNTYSAQRFYDAAKSLGLHPYRLPSANTSGPYTNPYGVQMGPCNFC
EECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCEECCCCCC
GYCSGYACYMYSKASPNLNILPALKQTPNFELRSKCHVLRVDLDDTKKRATGVTYVDPTG
CCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHCCCEEECCCC
REVHQPADLVIVAAFQYHNVHLLLLSGIGKPYDPISGEGVVGRNFAYQNLSTIKAFFDRD
CCCCCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCC
TFTNPFVGAGGNGVAVDDFNADNFDHGPLGFVGGSPLWVNQAGVKPVSGIAVPPGTPGWG
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCCCH
SAWKKAVKDYYAHTISMDAHGTNMSYRDVYLDLDPTYRDSYGQPLLRMTFDWKDNDIRMA
HHHHHHHHHHHHHEEEECCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEHH
QYVTGQMKKIAEAMGPKAIGVSTREFGKHFDTRAYQTTHLVGGAVMGTDPKTSVLNRYLQ
HHHHHHHHHHHHHHCCCEECCCHHHHHHHHCCCCEEEHEEECCEEECCCCHHHHHHHHHH
CWDVHNVFVMGASALPQGIGYNPTGIVAALAYWSARAIREQYLKNPAPLVTV
HHCCCEEEEEECHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]