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The map label for this gene is manC [H]

Identifier: 189352875

GI number: 189352875

Start: 1014659

End: 1016266

Strand: Reverse

Name: manC [H]

Synonym: BMULJ_04109

Alternate gene names: 189352875

Gene position: 1016266-1014659 (Counterclockwise)

Preceding gene: 189352876

Following gene: 189352873

Centisome position: 41.09

GC content: 69.28

Gene sequence:

>1608_bases
ATGACGCGCACGCTCCGCCCGGTGCCGCAGCCCGATCTGCCGCGCATTCTTCCCGTGATTCTCGCCGGCGGTTCGGGCAC
GCGGCTCTGGCCGCTGTCGCGCGAACAGCATCCGAAGCAGCTGATCGAGCTGGTCTCGGACGAATCGCCGCTATCGGCCA
CCGCGCGCCGGTTGAACGGGATCGCCAACGCATCGCTCGACGACCGGCTGCTGCTCGTCTGCGGCGAGCAGCATCGCTTC
ATGAGCGCCGCCCAAGTCGTCGGCCGCGGCGCGGGCACCGCGCGCATCCTGCTCGAGCCGAGCGCGCGCAACACCGCACC
CGCGCTGACGCTCGCCGCGCTCGACGCATCGGCGGACGCGGACGATCCGGTGCTGGCCGTGATGCCGGCCGACCATGTCA
TTGTCGACGTCGCCGCGTTTCAGGACGCGGTCGGCCGCGCCGCGCGCTATGCGCAGGATGGCGCGATCGTCACGCTCGGC
GTGCTGCCGCGCCGGGCCGAAACCGGCTACGGCTACATCCAGGTCGGCGAACCGCGCGCGGGCCGCCTCGGCGGTCAGGG
CGGCTATGCGATCGGACGCTTCGTCGAGAAGCCCGACGCGACGCTCGCCGAACGCTATCTGCAATCGGGCGACTACTGGT
GGAACAGCGGGATCTTCGTCACGCGCGCGTCGGTCTGGCTCAAGGCGATCGAGGCGCTCGCACCGGAGATCCATGCGGCG
TGCGAAGCCGCGTGGCGCGCCGGCGTCGCCGACGATCCGTTCTTCCGCATCGACGCGGCAGCGTTCGACGCGTGTCCGTC
CGACTCGATCGACTACGCGGTGATGGAGCGTCTCGCGGACAGCCCCACGCTCGGCATCGACGGCATCGTCGTGCCGCTCG
CGGCCGGCTGGTCCGACGTCGGCACCTGGGATGCGATCTGGGAAATCATGCCGAAGGACGCGCACGGCAACGTCGCGCGC
GGCACGGTCGTATTCGAGGACACGCACGACAGTCTCGTGCGTTCCGAAGGACGCCTCGTCGCGTGCGTCGGGATGAAGGA
CGTCGTCGTGATCGAAACGCCCGATGCGGTGCTCGTCGCGAACAAGCACGACGGGCAGCGCGTGAAGAACATCGTCGCGC
GGCTGAAGATGGATCGTCGCCCGCAAGTGAGCGAACACCGCAAGGTGCAGCGGCCGTGGGGGCATTACGATTCGATCGAT
CTCGGCGAGCGCTTCCAGGTGAAGCGGATCGTCGTCGAGCCCGGCAAGCAGCTGTCGCTGCAGATGCACTATCACCGCGC
CGAGCACTGGATCGTCGTGCGCGGCACCGCGCGCGTCACGCGCGGCAGCGACACGTTCCTGCTCAGCGAGAACGAATCGA
CCTATATCGCCGTCGGCGAGGTTCATCGGCTCGAGAATCCGGGGCGCATCCCGCTCGAGATCATCGAGGTGCAGTCGGGC
GACTATCTCGGCGAGGACGACATCGTGCGTTTCGACGACCAGTACGGACGCGCGGTCGTCGATGCCGGGCCGCCGCGCCG
GCCGTCCTCGAGCTTGCCGCCCGAACCGGCCCGGGTCGAGCCGGCAGCGGACGCCGAGACGACGGCCGAGCGCGACATCG
TTCGATAA

Upstream 100 bases:

>100_bases
TGCTGTCGCGCGTCGTGTCGGCGGCCGCGCCGGCCGACGACGATGCACGTACGGGCAGCCGCGCGCCGCATCGGCTGCCG
GCCGACACGGGAGTCAATCG

Downstream 100 bases:

>100_bases
GTCGTACGAATCGCGGCGGCGCAGCGCAGCCATGCTCGACCGCCCGCGCGTTGCATCAGCATGCCGCCAGCGCTGATCGC
GATGCGCGATGGGCCGACCG

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MTRTLRPVPQPDLPRILPVILAGGSGTRLWPLSREQHPKQLIELVSDESPLSATARRLNGIANASLDDRLLLVCGEQHRF
MSAAQVVGRGAGTARILLEPSARNTAPALTLAALDASADADDPVLAVMPADHVIVDVAAFQDAVGRAARYAQDGAIVTLG
VLPRRAETGYGYIQVGEPRAGRLGGQGGYAIGRFVEKPDATLAERYLQSGDYWWNSGIFVTRASVWLKAIEALAPEIHAA
CEAAWRAGVADDPFFRIDAAAFDACPSDSIDYAVMERLADSPTLGIDGIVVPLAAGWSDVGTWDAIWEIMPKDAHGNVAR
GTVVFEDTHDSLVRSEGRLVACVGMKDVVVIETPDAVLVANKHDGQRVKNIVARLKMDRRPQVSEHRKVQRPWGHYDSID
LGERFQVKRIVVEPGKQLSLQMHYHRAEHWIVVRGTARVTRGSDTFLLSENESTYIAVGEVHRLENPGRIPLEIIEVQSG
DYLGEDDIVRFDDQYGRAVVDAGPPRRPSSSLPPEPARVEPAADAETTAERDIVR

Sequences:

>Translated_535_residues
MTRTLRPVPQPDLPRILPVILAGGSGTRLWPLSREQHPKQLIELVSDESPLSATARRLNGIANASLDDRLLLVCGEQHRF
MSAAQVVGRGAGTARILLEPSARNTAPALTLAALDASADADDPVLAVMPADHVIVDVAAFQDAVGRAARYAQDGAIVTLG
VLPRRAETGYGYIQVGEPRAGRLGGQGGYAIGRFVEKPDATLAERYLQSGDYWWNSGIFVTRASVWLKAIEALAPEIHAA
CEAAWRAGVADDPFFRIDAAAFDACPSDSIDYAVMERLADSPTLGIDGIVVPLAAGWSDVGTWDAIWEIMPKDAHGNVAR
GTVVFEDTHDSLVRSEGRLVACVGMKDVVVIETPDAVLVANKHDGQRVKNIVARLKMDRRPQVSEHRKVQRPWGHYDSID
LGERFQVKRIVVEPGKQLSLQMHYHRAEHWIVVRGTARVTRGSDTFLLSENESTYIAVGEVHRLENPGRIPLEIIEVQSG
DYLGEDDIVRFDDQYGRAVVDAGPPRRPSSSLPPEPARVEPAADAETTAERDIVR
>Mature_534_residues
TRTLRPVPQPDLPRILPVILAGGSGTRLWPLSREQHPKQLIELVSDESPLSATARRLNGIANASLDDRLLLVCGEQHRFM
SAAQVVGRGAGTARILLEPSARNTAPALTLAALDASADADDPVLAVMPADHVIVDVAAFQDAVGRAARYAQDGAIVTLGV
LPRRAETGYGYIQVGEPRAGRLGGQGGYAIGRFVEKPDATLAERYLQSGDYWWNSGIFVTRASVWLKAIEALAPEIHAAC
EAAWRAGVADDPFFRIDAAAFDACPSDSIDYAVMERLADSPTLGIDGIVVPLAAGWSDVGTWDAIWEIMPKDAHGNVARG
TVVFEDTHDSLVRSEGRLVACVGMKDVVVIETPDAVLVANKHDGQRVKNIVARLKMDRRPQVSEHRKVQRPWGHYDSIDL
GERFQVKRIVVEPGKQLSLQMHYHRAEHWIVVRGTARVTRGSDTFLLSENESTYIAVGEVHRLENPGRIPLEIIEVQSGD
YLGEDDIVRFDDQYGRAVVDAGPPRRPSSSLPPEPARVEPAADAETTAERDIVR

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=485, Percent_Identity=50.9278350515464, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 58320; Mature: 58188

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTLRPVPQPDLPRILPVILAGGSGTRLWPLSREQHPKQLIELVSDESPLSATARRLNG
CCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
IANASLDDRLLLVCGEQHRFMSAAQVVGRGAGTARILLEPSARNTAPALTLAALDASADA
HCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCC
DDPVLAVMPADHVIVDVAAFQDAVGRAARYAQDGAIVTLGVLPRRAETGYGYIQVGEPRA
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCC
GRLGGQGGYAIGRFVEKPDATLAERYLQSGDYWWNSGIFVTRASVWLKAIEALAPEIHAA
CCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHH
CEAAWRAGVADDPFFRIDAAAFDACPSDSIDYAVMERLADSPTLGIDGIVVPLAAGWSDV
HHHHHHCCCCCCCCEEEEHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCC
GTWDAIWEIMPKDAHGNVARGTVVFEDTHDSLVRSEGRLVACVGMKDVVVIETPDAVLVA
CCHHHHHHHCCCCCCCCEEECEEEEECCHHHHHHCCCCEEEEECCCCEEEEECCCEEEEE
NKHDGQRVKNIVARLKMDRRPQVSEHRKVQRPWGHYDSIDLGERFQVKRIVVEPGKQLSL
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEE
QMHYHRAEHWIVVRGTARVTRGSDTFLLSENESTYIAVGEVHRLENPGRIPLEIIEVQSG
EEEEECCCEEEEEECCEEEECCCCEEEEECCCCCEEEEEEEEECCCCCCCCEEEEEECCC
DYLGEDDIVRFDDQYGRAVVDAGPPRRPSSSLPPEPARVEPAADAETTAERDIVR
CCCCCCCEEEECHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
TRTLRPVPQPDLPRILPVILAGGSGTRLWPLSREQHPKQLIELVSDESPLSATARRLNG
CCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
IANASLDDRLLLVCGEQHRFMSAAQVVGRGAGTARILLEPSARNTAPALTLAALDASADA
HCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCC
DDPVLAVMPADHVIVDVAAFQDAVGRAARYAQDGAIVTLGVLPRRAETGYGYIQVGEPRA
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCC
GRLGGQGGYAIGRFVEKPDATLAERYLQSGDYWWNSGIFVTRASVWLKAIEALAPEIHAA
CCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHH
CEAAWRAGVADDPFFRIDAAAFDACPSDSIDYAVMERLADSPTLGIDGIVVPLAAGWSDV
HHHHHHCCCCCCCCEEEEHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCC
GTWDAIWEIMPKDAHGNVARGTVVFEDTHDSLVRSEGRLVACVGMKDVVVIETPDAVLVA
CCHHHHHHHCCCCCCCCEEECEEEEECCHHHHHHCCCCEEEEECCCCEEEEECCCEEEEE
NKHDGQRVKNIVARLKMDRRPQVSEHRKVQRPWGHYDSIDLGERFQVKRIVVEPGKQLSL
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEE
QMHYHRAEHWIVVRGTARVTRGSDTFLLSENESTYIAVGEVHRLENPGRIPLEIIEVQSG
EEEEECCCEEEEEECCEEEECCCCEEEEECCCCCEEEEEEEEECCCCCCCCEEEEEECCC
DYLGEDDIVRFDDQYGRAVVDAGPPRRPSSSLPPEPARVEPAADAETTAERDIVR
CCCCCCCEEEECHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]