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The map label for this gene is hexR [H]

Identifier: 189352846

GI number: 189352846

Start: 970858

End: 971802

Strand: Direct

Name: hexR [H]

Synonym: BMULJ_04080

Alternate gene names: 189352846

Gene position: 970858-971802 (Clockwise)

Preceding gene: 189352843

Following gene: 189352847

Centisome position: 39.26

GC content: 70.9

Gene sequence:

>945_bases
ATGACGCTTTCCGTTCCTCCCGATGTCGGTGCCGACGAACCCGCGATCGCCGAGCGCATTGCGGCCGCGATGCCGTCGAT
GACGCCGATCCACCGGCGCATGGGCGAGTTCGTGCTGGCGAATCCGTTTCGCGCGGCGACGATGCGGATCGACGAGCTCG
CCCTTGCGGTGAACGCGTCGATCGCGACCGCGAACCGCTTCGCGAAGGCGCTCGGCTTCGACGGCTATCCGGCGATGCGC
GCGGCGCTCGTGCGCGGTTTCGAGGCGACGCTCGCGCCGGTCGAACGGCTGCGCTCCGCGCAGGAGCAGGAACCCGGCGT
GCGCGGCAGCGCCTGGATCGACACGGTGTTCGATCAGGCGGTCGCGAATATCGAGAACACGCGCGCGCAGCTGAACGCCG
CCGACGTCGAGGCCGCCGTCGAGGCGATCGTCGGCGCGCGGCGCGTGCTGATTCTCGGCGCCGGGTCGAGCGCGTTTCTC
GCGGGGCTGATGGAGCACGGGCTCTCGGTGTGTCACGACAACGTGCAGTCGCTCGCGCTGCTCGGCGGCCCGTCGCATGC
GGCGCGGCGCCTCTACACGGCCGATGCGCGCGACCTCGTGATCGCGCTCGCGTTTCCGCGCTACGTGAAGGACACGGTCG
AGCTCGCCACGCGGGCGGCTGCGCGCGGCGCACGCGTGCTCGCGATCACCGACGGCCGCGAATCGCCGCTCGCGCCGATC
GCCTCGCTGAGTCTGTACGTGAAGGCCGAGCGGCGCTTCGCGGCGACGTCCGAAGCGGCCGTGCTGGCGACGATCGAAGC
GCTGATCGACGCGGTCGCGCTGCGCACGCACCGTTCCGCGAAATCCGCGGCCGAGATGACCGAATTCGTGCTGCCGTGGC
TCGTGCAGCCGCAAGCGGCCGTTCCCGCTCCGAACCTTTCCTTTCCCCGCCCGGACCCATCATGA

Upstream 100 bases:

>100_bases
CGGCGAGCGCGCACCCGCGTGACAACCCTGATGAAAGTTTATTTTTTCCGCCTTGCGGATTGTGTAAATTGATTTACATC
TTCGTTGCGGCCTTCCGTCC

Downstream 100 bases:

>100_bases
CTTCACCCGCGATCGTCGCGATTCACGGCGGCGCAGGCACGATCCTGCGCGATGCAATGGACACCGACACCGAACGGCAG
TACCGCGCGGAGCTGACTGC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTLSVPPDVGADEPAIAERIAAAMPSMTPIHRRMGEFVLANPFRAATMRIDELALAVNASIATANRFAKALGFDGYPAMR
AALVRGFEATLAPVERLRSAQEQEPGVRGSAWIDTVFDQAVANIENTRAQLNAADVEAAVEAIVGARRVLILGAGSSAFL
AGLMEHGLSVCHDNVQSLALLGGPSHAARRLYTADARDLVIALAFPRYVKDTVELATRAAARGARVLAITDGRESPLAPI
ASLSLYVKAERRFAATSEAAVLATIEALIDAVALRTHRSAKSAAEMTEFVLPWLVQPQAAVPAPNLSFPRPDPS

Sequences:

>Translated_314_residues
MTLSVPPDVGADEPAIAERIAAAMPSMTPIHRRMGEFVLANPFRAATMRIDELALAVNASIATANRFAKALGFDGYPAMR
AALVRGFEATLAPVERLRSAQEQEPGVRGSAWIDTVFDQAVANIENTRAQLNAADVEAAVEAIVGARRVLILGAGSSAFL
AGLMEHGLSVCHDNVQSLALLGGPSHAARRLYTADARDLVIALAFPRYVKDTVELATRAAARGARVLAITDGRESPLAPI
ASLSLYVKAERRFAATSEAAVLATIEALIDAVALRTHRSAKSAAEMTEFVLPWLVQPQAAVPAPNLSFPRPDPS
>Mature_313_residues
TLSVPPDVGADEPAIAERIAAAMPSMTPIHRRMGEFVLANPFRAATMRIDELALAVNASIATANRFAKALGFDGYPAMRA
ALVRGFEATLAPVERLRSAQEQEPGVRGSAWIDTVFDQAVANIENTRAQLNAADVEAAVEAIVGARRVLILGAGSSAFLA
GLMEHGLSVCHDNVQSLALLGGPSHAARRLYTADARDLVIALAFPRYVKDTVELATRAAARGARVLAITDGRESPLAPIA
SLSLYVKAERRFAATSEAAVLATIEALIDAVALRTHRSAKSAAEMTEFVLPWLVQPQAAVPAPNLSFPRPDPS

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=235, Percent_Identity=24.6808510638298, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 33234; Mature: 33103

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSVPPDVGADEPAIAERIAAAMPSMTPIHRRMGEFVLANPFRAATMRIDELALAVNAS
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCH
IATANRFAKALGFDGYPAMRAALVRGFEATLAPVERLRSAQEQEPGVRGSAWIDTVFDQA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VANIENTRAQLNAADVEAAVEAIVGARRVLILGAGSSAFLAGLMEHGLSVCHDNVQSLAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
LGGPSHAARRLYTADARDLVIALAFPRYVKDTVELATRAAARGARVLAITDGRESPLAPI
CCCCHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHH
ASLSLYVKAERRFAATSEAAVLATIEALIDAVALRTHRSAKSAAEMTEFVLPWLVQPQAA
HHHHHEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VPAPNLSFPRPDPS
CCCCCCCCCCCCCC
>Mature Secondary Structure 
TLSVPPDVGADEPAIAERIAAAMPSMTPIHRRMGEFVLANPFRAATMRIDELALAVNAS
CCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCH
IATANRFAKALGFDGYPAMRAALVRGFEATLAPVERLRSAQEQEPGVRGSAWIDTVFDQA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VANIENTRAQLNAADVEAAVEAIVGARRVLILGAGSSAFLAGLMEHGLSVCHDNVQSLAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
LGGPSHAARRLYTADARDLVIALAFPRYVKDTVELATRAAARGARVLAITDGRESPLAPI
CCCCHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHH
ASLSLYVKAERRFAATSEAAVLATIEALIDAVALRTHRSAKSAAEMTEFVLPWLVQPQAA
HHHHHEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VPAPNLSFPRPDPS
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]