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The map label for this gene is betT [C]

Identifier: 189352845

GI number: 189352845

Start: 968528

End: 970549

Strand: Reverse

Name: betT [C]

Synonym: BMULJ_04079

Alternate gene names: 189352845

Gene position: 970549-968528 (Counterclockwise)

Preceding gene: 189352854

Following gene: 189352844

Centisome position: 39.24

GC content: 68.5

Gene sequence:

>2022_bases
ATGCCCGATTCCCGTTCCTCGCCACGTACGACGTTCAAGCCCCAGGTCGTGCTGCCGTCGCTCGCGCTGATCGGCGCGTT
GCTCGTCGTCTGTGCGCTGCTGCCCGACGAGGCCGGCGCGCTGTTCAGCGCCGGCCAGCAATGGGTCGTCGCGCGCTTCG
ACTGGTTCTATGTGCTGGCCGTCACGGCGTTTCTCGTGTTCCTCGTGCTGATCGCGGCCAGCGATTTCGGCAACATCCGG
CTCGGCCCCGACGATGCGGAGCCCGAATTCAGCTTCGTCTCGTGGACGGCGATGCTGTTCGCGGCCGGCATGGGTATCGG
CCTGATGTACTTCGGCGTCGGCGAGCCGATGCAGCACTTCCTGAAGCCGCCGACCGTCGAGCCCGCTTCGCCCGGCGCCG
CGCGCGAAGCGATGCTGATGACGTTCTTTCACTGGGGCTTTCATGCGTGGGCGATCTACGGGCTGATGGGCCTCGTGCTC
GCGTACTTCGGCTTTCGCTACAACCTGCCGCTCACGCTGCGCTCGGGGCTCTATCCGGTGCTGCGCGAGCGCGTGAACGG
CTGGATCGGCCACGCGGTCGATGCGTTCGCGCTGGTCGGCACGGTCGCCGGCATTGCGACGACGCTCGGCTACGGCGTGA
TGCAGATCAGCGCCGGGCTGCACACCGTCGCCGGCTGGGATACGGGCGGCAACGCGTTTCGCGTCGGACTCGTCGCGCTG
GTCGTGATCCTCGCGGGGCTGTCGGCGGCGAGCGGCCTCGACAAGGGCGTGCGGCGCCTGTCCGAGCTGAATCTGCTGCT
GGCATTCCTGCTGCTCGCGTTCGTCGCGATCGCCGGGCCGACCACGTTCCTGTTGCGCGCGCTCAGCGACAACATCGGCC
AGTATCTGTCGAGCCTCGTCGACCTGTCGTTCCGGACGTATGCGTATGCGCCGCCGCGCGACGAAGGCTGGTTCGGCGGC
TGGACGATTCTCTACTGGGCGTGGTGGGTGTCGTGGTCGCCGTTCGTCGGGATGTTCATCGCGCGCATTTCGCGCGGCCG
CACGATCCGTCAGTTCGTGATCGGCGTGCTGCTCGTGCCGACCGCGTTCAACCTCGTCTGGATGACCGTGTTCGGCAACA
GCGCGATCTGGCTCGACGCGCACGACGCGGCCGGTGCGCTCGCGCAGACGGCCACCAACGTCGACGCCCTGCTGTTCCGC
TTCTTCGATTTCCTGCCGCTGTCGCAGTTGCTTTCGATCGTGGCGATCCTGCTGATCGCGGTGTTCTTCGTCACGTCGGC
CGATTCCGGCGCGTTCGTGATCGATCAGATCGCGACGCGCGGCGCCGCGCGCTCGCCGGTCTGGCAGCGGCTGTTCTGGG
CCGCGCTGCTCGGCGTGACGGCAGCCGTGCTGCTCGTCGCCGGCGGCCTCGGCGCGCTGCAGGCGATGACGCTGATGGCC
GCGTTGCCGGTGGCCATCATCATGCTCGCGTTGTGCTACGGCCTCTGGCGCGGGCTCGCCGCCGATCGCGCGCACTACTC
GCAGGACGTCGCGCCCGCGACGAGCTTCTGGACCGGCCAGCACTGGCGCCATCGTCTGACGCATATCCTGCGCCAGACGA
CCGAAGCCGATGCGCGCCAGTTCGTCGCCGACACCGTGATGCCCGCGCTGCGCAAGGTCGCCGACGAATTGCGCGCGGGC
GGCGTCGATGCGCACGTGCAGCGCGACAGCGACGATGCGGTGCGGCTCACGGTGCCGACCGCCGAGCAGCGCGACTTCGT
CTACGGCGTGCGCGTGACCGCCAAAACCGCGCCCGCGTTCCTGATGCGCGAAGCGGCGGAGCCGCAGTCGGCGCGCCCGC
ATGTGTACGGGATCATTACGTTCTTCGAGGACGGGCGGCTCGGTTACGACATCGAATACCTGCGCGGCGACGAAGTGATC
GCCGACGTGCTGCGCCAGTACGAGCGCTACGTGTCGCTCGCGGCCGACAAGCGCACGCATCTGCTGAGCCGCGCGCCGGG
ACACGCGACGGAGTCGGAATGA

Upstream 100 bases:

>100_bases
ACACCGGGGTACATTCGATGCACGCCGCATCAGGGTCCGGCGCGCGATGCGCGGCCGGAGCGGCGTCGCGCTTCGTTGCA
CCCGCTACTGGATGCCCGCC

Downstream 100 bases:

>100_bases
ACGCGCGCCCCATCCCGCCCGCGACGCATGCAGGATCCGTGCGATGAGCGGCATCCTGCACGATCGCACTGCCGACTTCG
TCGCGCTCGGCACGCTCGTT

Product: high-affinity choline transport protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MPDSRSSPRTTFKPQVVLPSLALIGALLVVCALLPDEAGALFSAGQQWVVARFDWFYVLAVTAFLVFLVLIAASDFGNIR
LGPDDAEPEFSFVSWTAMLFAAGMGIGLMYFGVGEPMQHFLKPPTVEPASPGAAREAMLMTFFHWGFHAWAIYGLMGLVL
AYFGFRYNLPLTLRSGLYPVLRERVNGWIGHAVDAFALVGTVAGIATTLGYGVMQISAGLHTVAGWDTGGNAFRVGLVAL
VVILAGLSAASGLDKGVRRLSELNLLLAFLLLAFVAIAGPTTFLLRALSDNIGQYLSSLVDLSFRTYAYAPPRDEGWFGG
WTILYWAWWVSWSPFVGMFIARISRGRTIRQFVIGVLLVPTAFNLVWMTVFGNSAIWLDAHDAAGALAQTATNVDALLFR
FFDFLPLSQLLSIVAILLIAVFFVTSADSGAFVIDQIATRGAARSPVWQRLFWAALLGVTAAVLLVAGGLGALQAMTLMA
ALPVAIIMLALCYGLWRGLAADRAHYSQDVAPATSFWTGQHWRHRLTHILRQTTEADARQFVADTVMPALRKVADELRAG
GVDAHVQRDSDDAVRLTVPTAEQRDFVYGVRVTAKTAPAFLMREAAEPQSARPHVYGIITFFEDGRLGYDIEYLRGDEVI
ADVLRQYERYVSLAADKRTHLLSRAPGHATESE

Sequences:

>Translated_673_residues
MPDSRSSPRTTFKPQVVLPSLALIGALLVVCALLPDEAGALFSAGQQWVVARFDWFYVLAVTAFLVFLVLIAASDFGNIR
LGPDDAEPEFSFVSWTAMLFAAGMGIGLMYFGVGEPMQHFLKPPTVEPASPGAAREAMLMTFFHWGFHAWAIYGLMGLVL
AYFGFRYNLPLTLRSGLYPVLRERVNGWIGHAVDAFALVGTVAGIATTLGYGVMQISAGLHTVAGWDTGGNAFRVGLVAL
VVILAGLSAASGLDKGVRRLSELNLLLAFLLLAFVAIAGPTTFLLRALSDNIGQYLSSLVDLSFRTYAYAPPRDEGWFGG
WTILYWAWWVSWSPFVGMFIARISRGRTIRQFVIGVLLVPTAFNLVWMTVFGNSAIWLDAHDAAGALAQTATNVDALLFR
FFDFLPLSQLLSIVAILLIAVFFVTSADSGAFVIDQIATRGAARSPVWQRLFWAALLGVTAAVLLVAGGLGALQAMTLMA
ALPVAIIMLALCYGLWRGLAADRAHYSQDVAPATSFWTGQHWRHRLTHILRQTTEADARQFVADTVMPALRKVADELRAG
GVDAHVQRDSDDAVRLTVPTAEQRDFVYGVRVTAKTAPAFLMREAAEPQSARPHVYGIITFFEDGRLGYDIEYLRGDEVI
ADVLRQYERYVSLAADKRTHLLSRAPGHATESE
>Mature_672_residues
PDSRSSPRTTFKPQVVLPSLALIGALLVVCALLPDEAGALFSAGQQWVVARFDWFYVLAVTAFLVFLVLIAASDFGNIRL
GPDDAEPEFSFVSWTAMLFAAGMGIGLMYFGVGEPMQHFLKPPTVEPASPGAAREAMLMTFFHWGFHAWAIYGLMGLVLA
YFGFRYNLPLTLRSGLYPVLRERVNGWIGHAVDAFALVGTVAGIATTLGYGVMQISAGLHTVAGWDTGGNAFRVGLVALV
VILAGLSAASGLDKGVRRLSELNLLLAFLLLAFVAIAGPTTFLLRALSDNIGQYLSSLVDLSFRTYAYAPPRDEGWFGGW
TILYWAWWVSWSPFVGMFIARISRGRTIRQFVIGVLLVPTAFNLVWMTVFGNSAIWLDAHDAAGALAQTATNVDALLFRF
FDFLPLSQLLSIVAILLIAVFFVTSADSGAFVIDQIATRGAARSPVWQRLFWAALLGVTAAVLLVAGGLGALQAMTLMAA
LPVAIIMLALCYGLWRGLAADRAHYSQDVAPATSFWTGQHWRHRLTHILRQTTEADARQFVADTVMPALRKVADELRAGG
VDAHVQRDSDDAVRLTVPTAEQRDFVYGVRVTAKTAPAFLMREAAEPQSARPHVYGIITFFEDGRLGYDIEYLRGDEVIA
DVLRQYERYVSLAADKRTHLLSRAPGHATESE

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=680, Percent_Identity=37.9411764705882, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1788102, Length=482, Percent_Identity=29.253112033195, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786224, Length=491, Percent_Identity=29.3279022403259, Blast_Score=169, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 73437; Mature: 73306

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCCCC
>Mature Secondary Structure 
PDSRSSPRTTFKPQVVLPSLALIGALLVVCALLPDEAGALFSAGQQWVVARFDWFYVLA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEHHHHHHHHHH
VTAFLVFLVLIAASDFGNIRLGPDDAEPEFSFVSWTAMLFAAGMGIGLMYFGVGEPMQHF
HHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKPPTVEPASPGAAREAMLMTFFHWGFHAWAIYGLMGLVLAYFGFRYNLPLTLRSGLYPV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHH
LRERVNGWIGHAVDAFALVGTVAGIATTLGYGVMQISAGLHTVAGWDTGGNAFRVGLVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHH
VVILAGLSAASGLDKGVRRLSELNLLLAFLLLAFVAIAGPTTFLLRALSDNIGQYLSSLV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DLSFRTYAYAPPRDEGWFGGWTILYWAWWVSWSPFVGMFIARISRGRTIRQFVIGVLLVP
HHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TAFNLVWMTVFGNSAIWLDAHDAAGALAQTATNVDALLFRFFDFLPLSQLLSIVAILLIA
HHHHHHEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VFFVTSADSGAFVIDQIATRGAARSPVWQRLFWAALLGVTAAVLLVAGGLGALQAMTLMA
HHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ALPVAIIMLALCYGLWRGLAADRAHYSQDVAPATSFWTGQHWRHRLTHILRQTTEADARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
FVADTVMPALRKVADELRAGGVDAHVQRDSDDAVRLTVPTAEQRDFVYGVRVTAKTAPAF
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCEEEEEEEECCHHHHH
LMREAAEPQSARPHVYGIITFFEDGRLGYDIEYLRGDEVIADVLRQYERYVSLAADKRTH
HHHHHCCCCCCCCCEEEEEEEEECCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LLSRAPGHATESE
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]