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The map label for this gene is marR [H]

Identifier: 189352725

GI number: 189352725

Start: 828493

End: 829014

Strand: Direct

Name: marR [H]

Synonym: BMULJ_03957

Alternate gene names: 189352725

Gene position: 828493-829014 (Clockwise)

Preceding gene: 189352722

Following gene: 189352731

Centisome position: 33.5

GC content: 64.18

Gene sequence:

>522_bases
ATGCACCGCTTGCGCCGATTTGAGGGTGTACACTCCATGTCTTTCGGTTTTCATGCGGTGCGAGCCGCGACTTTCATGGC
GTCTTCCAGGGATTCCTACGACTTTCACGACCAGATCGGGCACTTGCTGCGCCGCGCGTATCAGCGACACGTCGCGATCT
TCCAGGAAGCGATTCCGGATTCGGATCTGACGGCCGCGCAGTTCGTCACGCTGTGCGCCGTGAAGGAGCGGCAGGCGAGT
TCGCTGAACGACATCGTGAAGGCGACCGCGATCGACCAGGCGACGATACGCGGCGTCGTCGAGCGGTTGAAGACGCGCGC
GCTGATCGAGGTGTTGCCCGATCCGAACGACGGCCGCAAGCTGCTCGTGCGTGCGACGGCCGCCGGCCTCGCACTGATCG
ACCGCACGGTGCCGTTCGCGCGTCAGGTGACGGAACGCACGTACGGGACGCTCAATCCGGGCGAGCGCGTCGCGCTGCAG
TTTCTGCTGCGCAAGATGATGGACGAAGAGGGCGCCGAGTGA

Upstream 100 bases:

>100_bases
GAACGCGCCGGAGTCGCGCGGCGCGGGTTACACCGCGATGCGCGCGCCAACCGGGCGCATCGCGCCGCCGTCCGTTGACG
CACCGCAATGAGGCATCGCC

Downstream 100 bases:

>100_bases
CGCGTGATCGGCGCGTTCGGTTCGCGGCCGCCTCGATCGCGACGAACGGCGGCTAGGCCGTATCGGCCGCCGCGCGCGTG
CCGGCCGCCTCGCCTGCGAG

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MHRLRRFEGVHSMSFGFHAVRAATFMASSRDSYDFHDQIGHLLRRAYQRHVAIFQEAIPDSDLTAAQFVTLCAVKERQAS
SLNDIVKATAIDQATIRGVVERLKTRALIEVLPDPNDGRKLLVRATAAGLALIDRTVPFARQVTERTYGTLNPGERVALQ
FLLRKMMDEEGAE

Sequences:

>Translated_173_residues
MHRLRRFEGVHSMSFGFHAVRAATFMASSRDSYDFHDQIGHLLRRAYQRHVAIFQEAIPDSDLTAAQFVTLCAVKERQAS
SLNDIVKATAIDQATIRGVVERLKTRALIEVLPDPNDGRKLLVRATAAGLALIDRTVPFARQVTERTYGTLNPGERVALQ
FLLRKMMDEEGAE
>Mature_173_residues
MHRLRRFEGVHSMSFGFHAVRAATFMASSRDSYDFHDQIGHLLRRAYQRHVAIFQEAIPDSDLTAAQFVTLCAVKERQAS
SLNDIVKATAIDQATIRGVVERLKTRALIEVLPDPNDGRKLLVRATAAGLALIDRTVPFARQVTERTYGTLNPGERVALQ
FLLRKMMDEEGAE

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=143, Percent_Identity=26.5734265734266, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 19437; Mature: 19437

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRLRRFEGVHSMSFGFHAVRAATFMASSRDSYDFHDQIGHLLRRAYQRHVAIFQEAIPD
CCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SDLTAAQFVTLCAVKERQASSLNDIVKATAIDQATIRGVVERLKTRALIEVLPDPNDGRK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LLVRATAAGLALIDRTVPFARQVTERTYGTLNPGERVALQFLLRKMMDEEGAE
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHRLRRFEGVHSMSFGFHAVRAATFMASSRDSYDFHDQIGHLLRRAYQRHVAIFQEAIPD
CCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SDLTAAQFVTLCAVKERQASSLNDIVKATAIDQATIRGVVERLKTRALIEVLPDPNDGRK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LLVRATAAGLALIDRTVPFARQVTERTYGTLNPGERVALQFLLRKMMDEEGAE
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]