Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 189352720

GI number: 189352720

Start: 822967

End: 824127

Strand: Reverse

Name: nahR [H]

Synonym: BMULJ_03952

Alternate gene names: 189352720

Gene position: 824127-822967 (Counterclockwise)

Preceding gene: 189352721

Following gene: 189352718

Centisome position: 33.32

GC content: 70.2

Gene sequence:

>1161_bases
ATGCGTGAGCGCGTAGCACCGCGCGCCGCCGAGCGCGACGCCGCCGACGCCGACGCAGCGAACGCGCTCGACGTGCTCGA
TGCGCGGCTGATGCGCATGCTGCTCGTGCTGCTGACCGAGCGCACGGTGTCGCGCGCGGCCGTGCGGCTGAACATGTCGC
AGCCGGCGACGAGTGCTGCGCTGAAACGGCTGCGTCTGCTGCTCGGCGATCCGCTGCTCGTGCGCAGTCGCTACGGGATG
GTGCCGACCGAGTTCGGCGGCCGGCTGATCGAGCCGCTGCGCAATGCGCTGCGCGTGATCGACTTCATCCGGCTCCAGCA
GCCGCGCTTCGACGCGCGTACGTCGGTACGCACCTACCGGATCGGCTGTCCCGACTATCTGAACGTGCTGTTCGTGCCGA
AGCTCGTCGCGCTGTTCCGCGCACGCGCGCCGCAGGCGCAGCTCGTGTTTCATCCGCTCGGCGACGGCTTCGACGACGAA
CGCGCGCTCGCCAACGGCGAACTCGATGTCGTGATCGACAATCGCCCTGCACGCGGTGCGCGATTCCGGCAGGAACGGCT
GTTCGACGACCGGGTCGTGTGCCTGATGCGCGCGACGCACCCGCTCGCGCGGCGCGGTGTGATCACGGCCGCCGAATTCG
CCGATGTGCCGCAGCTGTGCCCGACGCCGTCGTGGCTCGAAGCGTCCGGTGCGATCGACCGGCAACTCGAGCGCGTCGGA
CTGCGGCGGCGCATCGTCGTCACGCTGCCGCACTTCGAGCTGGCCGCGCATGCGCTCGTGCGCTCGGACCTCGTGCTGAC
CACGACATACCGGCTCGCGTGCCATTACGCGAAACTGCTGCCGCTGTGCGTCGTCGCGTTGCCGGCCGATCCGCCCGAGG
TCGGCTATCGGATCACATGGAACGAAGCGGGTTCGTGCGTCGACGGCGTGCGCTGGCTGCGCGAGCTGATTGCCGAAGCG
ACGCGCAGTTGGCTCGATGCCGAGGCTGCGCAGCCGGCCGTCACGGCGCTGCCTGCGTCGGCGACGTCGGCTGCATCGAC
CGCCGCGACGTCCGAACCTGCGCGCACACGGCGGGGTGGCCGTCCGTCACGTTGCACGTCGCGCTCCATTCGGACCGCGC
GCTGCGCACGTCACGCACGTATCGCGTCGAAACCGCACTGA

Upstream 100 bases:

>100_bases
GAACCGGCGCGGCCGCGCGCAGTCCTGCGCCCGGCCTGCGACTGTGCGCTCGTACTCGCCGCGCCAGCGCCGGCGCCGCA
TCGCCGCGACGGACCACGAC

Downstream 100 bases:

>100_bases
CCGTCGCGCCGTACGCGCGATCGCCCGCCCGCTGCGCTTTCTTACGATGCGTGCCGCGCGAACGCAAGCAGCACCGACAA
GGACACGATCGACCCGATCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRERVAPRAAERDAADADAANALDVLDARLMRMLLVLLTERTVSRAAVRLNMSQPATSAALKRLRLLLGDPLLVRSRYGM
VPTEFGGRLIEPLRNALRVIDFIRLQQPRFDARTSVRTYRIGCPDYLNVLFVPKLVALFRARAPQAQLVFHPLGDGFDDE
RALANGELDVVIDNRPARGARFRQERLFDDRVVCLMRATHPLARRGVITAAEFADVPQLCPTPSWLEASGAIDRQLERVG
LRRRIVVTLPHFELAAHALVRSDLVLTTTYRLACHYAKLLPLCVVALPADPPEVGYRITWNEAGSCVDGVRWLRELIAEA
TRSWLDAEAAQPAVTALPASATSAASTAATSEPARTRRGGRPSRCTSRSIRTARCARHARIASKPH

Sequences:

>Translated_386_residues
MRERVAPRAAERDAADADAANALDVLDARLMRMLLVLLTERTVSRAAVRLNMSQPATSAALKRLRLLLGDPLLVRSRYGM
VPTEFGGRLIEPLRNALRVIDFIRLQQPRFDARTSVRTYRIGCPDYLNVLFVPKLVALFRARAPQAQLVFHPLGDGFDDE
RALANGELDVVIDNRPARGARFRQERLFDDRVVCLMRATHPLARRGVITAAEFADVPQLCPTPSWLEASGAIDRQLERVG
LRRRIVVTLPHFELAAHALVRSDLVLTTTYRLACHYAKLLPLCVVALPADPPEVGYRITWNEAGSCVDGVRWLRELIAEA
TRSWLDAEAAQPAVTALPASATSAASTAATSEPARTRRGGRPSRCTSRSIRTARCARHARIASKPH
>Mature_386_residues
MRERVAPRAAERDAADADAANALDVLDARLMRMLLVLLTERTVSRAAVRLNMSQPATSAALKRLRLLLGDPLLVRSRYGM
VPTEFGGRLIEPLRNALRVIDFIRLQQPRFDARTSVRTYRIGCPDYLNVLFVPKLVALFRARAPQAQLVFHPLGDGFDDE
RALANGELDVVIDNRPARGARFRQERLFDDRVVCLMRATHPLARRGVITAAEFADVPQLCPTPSWLEASGAIDRQLERVG
LRRRIVVTLPHFELAAHALVRSDLVLTTTYRLACHYAKLLPLCVVALPADPPEVGYRITWNEAGSCVDGVRWLRELIAEA
TRSWLDAEAAQPAVTALPASATSAASTAATSEPARTRRGGRPSRCTSRSIRTARCARHARIASKPH

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=300, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=23.4527687296417, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081766, Length=283, Percent_Identity=21.9081272084806, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 42764; Mature: 42764

Theoretical pI: Translated: 10.94; Mature: 10.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRERVAPRAAERDAADADAANALDVLDARLMRMLLVLLTERTVSRAAVRLNMSQPATSAA
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHH
LKRLRLLLGDPLLVRSRYGMVPTEFGGRLIEPLRNALRVIDFIRLQQPRFDARTSVRTYR
HHHHHHHHCCCHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCEEEE
IGCPDYLNVLFVPKLVALFRARAPQAQLVFHPLGDGFDDERALANGELDVVIDNRPARGA
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCCCEEEEECCCCCCCH
RFRQERLFDDRVVCLMRATHPLARRGVITAAEFADVPQLCPTPSWLEASGAIDRQLERVG
HHHHHHHHHHHHHHHHHHCCHHHHCCCEEHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHC
LRRRIVVTLPHFELAAHALVRSDLVLTTTYRLACHYAKLLPLCVVALPADPPEVGYRITW
CCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEE
NEAGSCVDGVRWLRELIAEATRSWLDAEAAQPAVTALPASATSAASTAATSEPARTRRGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCHHHHCCC
RPSRCTSRSIRTARCARHARIASKPH
CCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRERVAPRAAERDAADADAANALDVLDARLMRMLLVLLTERTVSRAAVRLNMSQPATSAA
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHH
LKRLRLLLGDPLLVRSRYGMVPTEFGGRLIEPLRNALRVIDFIRLQQPRFDARTSVRTYR
HHHHHHHHCCCHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCEEEE
IGCPDYLNVLFVPKLVALFRARAPQAQLVFHPLGDGFDDERALANGELDVVIDNRPARGA
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCCCEEEEECCCCCCCH
RFRQERLFDDRVVCLMRATHPLARRGVITAAEFADVPQLCPTPSWLEASGAIDRQLERVG
HHHHHHHHHHHHHHHHHHCCHHHHCCCEEHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHC
LRRRIVVTLPHFELAAHALVRSDLVLTTTYRLACHYAKLLPLCVVALPADPPEVGYRITW
CCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEE
NEAGSCVDGVRWLRELIAEATRSWLDAEAAQPAVTALPASATSAASTAATSEPARTRRGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCHHHHCCC
RPSRCTSRSIRTARCARHARIASKPH
CCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]