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The map label for this gene is ybcL [H]

Identifier: 189352706

GI number: 189352706

Start: 808563

End: 809732

Strand: Reverse

Name: ybcL [H]

Synonym: BMULJ_03938

Alternate gene names: 189352706

Gene position: 809732-808563 (Counterclockwise)

Preceding gene: 189352708

Following gene: 189352698

Centisome position: 32.74

GC content: 74.36

Gene sequence:

>1170_bases
TTGGACGTTCGCGTTTACCTGCTCGCCGCCGCCGTGTTTCTCGCCGGCGTCGCCGAAAACATCTGCGTCGGCATCCTGCC
GGCGATCTCCGCCGGTCTTCACGTATCGGTCGCGGCCGCCGGCCAGCTCACGACGATCTTCTCCGCCGTATTCGCACTCG
CCGCGCTCGTCGCGGCCGCCTTCGTCGCGCGCATCGAACGGCGCACGGCCCTGCTCGCGTCGCTCGCCACATTTGCAGCC
GCGAACCTGTTCGCCGCCGCGAGCGCCGGGTATGCGAGCCTGTTCGCCGCGCGCGTGCTGATGGCCGCGAGCTGCGCGAT
GCTGATCCTCGTCGCGACGCGGCTCGCGGCCGAACTCGCGGCGCCGGCGCAGCGCGGCCGCGCGATCGGCATCGTGTTCA
TGGGAATCAGCGCGTCGCTCGTGCTCGGCGTGCCGATCGGGATGCGGATTGCCGACTGGGCCGGCTGGCGCGCCGTGTTC
GCGTCGATCGCGGTGCCCGCGCTGCCGCTCGCGATCTGGCTCGGCCGCCGGCTGCCGCGCATCGCGGCCGCCGCGCCCGC
CGACGCCGCGTCGCGCGCGCACGCGCCGCCGTATCGCGCCGTGCTCGGCCGCCCGACGCTGGTCGCCGCGCAGCTCGTGT
CGGTCGCGATGATCGGCGGGCATTTCACGCTGTTCGCCTATCTGACGCCGTATCTGCAGGCGGTGCTGTCGCCCGGCGCC
GCCGCGCTCGAAGCGCTGTACGTCGCGTTCGGCATCGCCGGCGTGATCGGCGCGTGGGCCGGCGGCACACTGTCCGACCG
GCTCGGCGCGCGGCGCGCGCTCGTCGCCTGCCCGGCGCTGTTCGTCGTCGCGATGGCCGTGCTGCCGGCCGCCGCCGCGA
CGCCGCTCGCGTTCGTACCCGCGATGATGCTATGGGGCGCGCTCAGCTGGGCGATCTCGCCGATCGCGCAGAACCATCTG
ATCCACGCGGCGCCCACGCTCGCCGATGCGAGCGTCGGCATCAACGTGTCCGCGATGCATGCGGGCGTCGCGCTCGGCGC
TGCATTCGGCGGCGTACTCGTCGAGCGCGGCGCGCTGCTGCTCGCGCCGTGGGCCGGCTGCGCGCTGGTCGCGCTCGCGC
TGGGCTGCGCGTGCGTCGCCGCGCGACCCGCTCACCACGCGCGCCGATAG

Upstream 100 bases:

>100_bases
GATAACCGAAGCCTCGCGTCGAAACCCATCCGTCGATTCGATCCGACGCGGCCGTCCGTTGCCGGGCCCCGCCGCGTCGC
GCGTACTGGAGGGGTCTGCG

Downstream 100 bases:

>100_bases
ATCTCGAGCGCGTCGGCCTCCGTCACTTCGCGCGGATTGTTGACGAGCAGGCGCGTCTGCAGCATCGCGTCCGCGGCCAT
CCGCGGCAGATCGCCTTCGC

Product: chloramphenicol resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDVRVYLLAAAVFLAGVAENICVGILPAISAGLHVSVAAAGQLTTIFSAVFALAALVAAAFVARIERRTALLASLATFAA
ANLFAAASAGYASLFAARVLMAASCAMLILVATRLAAELAAPAQRGRAIGIVFMGISASLVLGVPIGMRIADWAGWRAVF
ASIAVPALPLAIWLGRRLPRIAAAAPADAASRAHAPPYRAVLGRPTLVAAQLVSVAMIGGHFTLFAYLTPYLQAVLSPGA
AALEALYVAFGIAGVIGAWAGGTLSDRLGARRALVACPALFVVAMAVLPAAAATPLAFVPAMMLWGALSWAISPIAQNHL
IHAAPTLADASVGINVSAMHAGVALGAAFGGVLVERGALLLAPWAGCALVALALGCACVAARPAHHARR

Sequences:

>Translated_389_residues
MDVRVYLLAAAVFLAGVAENICVGILPAISAGLHVSVAAAGQLTTIFSAVFALAALVAAAFVARIERRTALLASLATFAA
ANLFAAASAGYASLFAARVLMAASCAMLILVATRLAAELAAPAQRGRAIGIVFMGISASLVLGVPIGMRIADWAGWRAVF
ASIAVPALPLAIWLGRRLPRIAAAAPADAASRAHAPPYRAVLGRPTLVAAQLVSVAMIGGHFTLFAYLTPYLQAVLSPGA
AALEALYVAFGIAGVIGAWAGGTLSDRLGARRALVACPALFVVAMAVLPAAAATPLAFVPAMMLWGALSWAISPIAQNHL
IHAAPTLADASVGINVSAMHAGVALGAAFGGVLVERGALLLAPWAGCALVALALGCACVAARPAHHARR
>Mature_389_residues
MDVRVYLLAAAVFLAGVAENICVGILPAISAGLHVSVAAAGQLTTIFSAVFALAALVAAAFVARIERRTALLASLATFAA
ANLFAAASAGYASLFAARVLMAASCAMLILVATRLAAELAAPAQRGRAIGIVFMGISASLVLGVPIGMRIADWAGWRAVF
ASIAVPALPLAIWLGRRLPRIAAAAPADAASRAHAPPYRAVLGRPTLVAAQLVSVAMIGGHFTLFAYLTPYLQAVLSPGA
AALEALYVAFGIAGVIGAWAGGTLSDRLGARRALVACPALFVVAMAVLPAAAATPLAFVPAMMLWGALSWAISPIAQNHL
IHAAPTLADASVGINVSAMHAGVALGAAFGGVLVERGALLLAPWAGCALVALALGCACVAARPAHHARR

Specific function: Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and inosine, as well as purine bases guanine, adenine and hypoxanthine, and purine base analogs 2,6- diaminopurine, 6-mercaptopurine and 2-fluoroadenine. Therefore plays a role

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. PbuE (TC 2.A.1.2.25) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787947, Length=340, Percent_Identity=27.6470588235294, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787808, Length=233, Percent_Identity=26.6094420600858, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693198, Length=341, Percent_Identity=22.8739002932551, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 39159; Mature: 39159

Theoretical pI: Translated: 11.00; Mature: 11.00

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRVYLLAAAVFLAGVAENICVGILPAISAGLHVSVAAAGQLTTIFSAVFALAALVAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
FVARIERRTALLASLATFAAANLFAAASAGYASLFAARVLMAASCAMLILVATRLAAELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APAQRGRAIGIVFMGISASLVLGVPIGMRIADWAGWRAVFASIAVPALPLAIWLGRRLPR
HHHHCCCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IAAAAPADAASRAHAPPYRAVLGRPTLVAAQLVSVAMIGGHFTLFAYLTPYLQAVLSPGA
HHHCCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
AALEALYVAFGIAGVIGAWAGGTLSDRLGARRALVACPALFVVAMAVLPAAAATPLAFVP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AMMLWGALSWAISPIAQNHLIHAAPTLADASVGINVSAMHAGVALGAAFGGVLVERGALL
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
LAPWAGCALVALALGCACVAARPAHHARR
EECHHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MDVRVYLLAAAVFLAGVAENICVGILPAISAGLHVSVAAAGQLTTIFSAVFALAALVAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
FVARIERRTALLASLATFAAANLFAAASAGYASLFAARVLMAASCAMLILVATRLAAELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APAQRGRAIGIVFMGISASLVLGVPIGMRIADWAGWRAVFASIAVPALPLAIWLGRRLPR
HHHHCCCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IAAAAPADAASRAHAPPYRAVLGRPTLVAAQLVSVAMIGGHFTLFAYLTPYLQAVLSPGA
HHHCCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
AALEALYVAFGIAGVIGAWAGGTLSDRLGARRALVACPALFVVAMAVLPAAAATPLAFVP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AMMLWGALSWAISPIAQNHLIHAAPTLADASVGINVSAMHAGVALGAAFGGVLVERGALL
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
LAPWAGCALVALALGCACVAARPAHHARR
EECHHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]