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The map label for this gene is ttuB [H]

Identifier: 189352693

GI number: 189352693

Start: 791267

End: 792619

Strand: Reverse

Name: ttuB [H]

Synonym: BMULJ_03925

Alternate gene names: 189352693

Gene position: 792619-791267 (Counterclockwise)

Preceding gene: 189352697

Following gene: 189352691

Centisome position: 32.05

GC content: 63.93

Gene sequence:

>1353_bases
ATGCCCATACTCACCGAGACCGCGGCATCGGCCGCGCCTGTCGACGAAACCGAAGAGCGCGTCTATCGCAAGGTGCTGCG
CCGCGTGCTGCCGCTCTTGCTGCTCTGCTACGTGGTCGCGTATCTCGACCGCGTCAACGTCGGTTTCGCGAAGCTGCAGA
TGCTCGATTCGCTCGGCCTCAGCGATACCATCTACGCGGTCGGCGCCAGCATCTTCTTCTGGGGATACTTTCTGTTCGAG
ATCCCGAGCAATCTGTTGCTGCATCGCTACGGCGCGCGGTTCTGGATCGCGCGCATCATGATCACGTGGGGCATCGTCTC
GTCGTCGCTTGCGTTCATCGCGCCGCTCGCGCGGTTCTTCCACGTCGAAGCGTCGACGATGTTCTACATCCTGCGGTTCC
TGCTCGGCGCATGCGAGGCCGGTTTCTTTCCGGGCGTGATCCTGTACATGAACTACTGGTTCCCTGCGCGCCGCCAGAGC
ACCGCCATGTCCGGGTTCCTGATCGCGATTCCGGTGAGCCTCACGCTCGGCGGCATCGTTTCCGGCTGGCTGATGGAAAA
CACGCACGGGTTGCTCGGCCTCGGCGGCTGGCAGTGGATGCTGCTGCTCGAAGGCATTCCGTCGATTCTCGTCGCGTTCG
TCGTGCTCGCGTTCATGGGCGACGGCATCGCGTCCGCGAAGTGGCTGTCCGCGAGCGAAAAGGCGCTGCTGCAGCGCAAT
CTCGAACAGGAAGGCACGCGCAAGACGCACAGCATCGGCGCGGCGTTTCGCAATCCGCACGTCTGGCTGCTCACGTTCAT
TCTGCTCACGTTCAACACGGGCTTTTACGGGCTCGCGTTCTGGTTGCCGTCGATCATTCGCGCGTCGGGCGTGCAAAGCC
CGCTGAGCATCGGGCTGCTGACCGCGATTCCGTATCTGAGCGCCGTCGTCGCGATGCTGTGGAATGCCGCGCATTCGCGC
CGTACCGGCGAGCGGCGGCTGCATGCGGCGATTCCGGCCGGCATCGGCGGCGTCGGACTGATGCTCAGCGCGTTCTTCGC
GAGCAACGTGCCGCTGTCGATCCTGTTCCTGACGATCTCGACCTGCGCGATCCTCGGCCTGATGCCGATCTACTGGACGT
TCCCCGGCCAGATTCTCGCCGGCACAGCCGCCGCGGCCGGCATCGCGCTGATCAACTCGATCGGCAACCTGTCCGGTTTC
ACCGGCTCGATGATTACCAGCGTCGCGAAAAACCTGACCGGCAACATCAACAACGGCACGTATGCGCTCGGCGCGTGCCT
GCTCGTCAGCTGCGTGCTGATTCTCGCGATCCCGAAACGGCTGCTCGACAACCGCGCCGACGAGCGCGAGTGA

Upstream 100 bases:

>100_bases
CGCCCGATCGCGCGTGCTACTTTAGTTACCGGTAACATTTCAGCCGGGCAGCCAACGTGCGCAACGCTCCGGCACACAAG
TAAAGATCCGGAGACACGTC

Downstream 100 bases:

>100_bases
GGTCGGCCCTTCGCGTCGGCGCGCGGCGGCGAATGCGGGCCGAACGGTTCGCAGACGCGCAACGCGCCAGCGCAACGGGC
GCGCTCGCCGGACGGCGGCG

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MPILTETAASAAPVDETEERVYRKVLRRVLPLLLLCYVVAYLDRVNVGFAKLQMLDSLGLSDTIYAVGASIFFWGYFLFE
IPSNLLLHRYGARFWIARIMITWGIVSSSLAFIAPLARFFHVEASTMFYILRFLLGACEAGFFPGVILYMNYWFPARRQS
TAMSGFLIAIPVSLTLGGIVSGWLMENTHGLLGLGGWQWMLLLEGIPSILVAFVVLAFMGDGIASAKWLSASEKALLQRN
LEQEGTRKTHSIGAAFRNPHVWLLTFILLTFNTGFYGLAFWLPSIIRASGVQSPLSIGLLTAIPYLSAVVAMLWNAAHSR
RTGERRLHAAIPAGIGGVGLMLSAFFASNVPLSILFLTISTCAILGLMPIYWTFPGQILAGTAAAAGIALINSIGNLSGF
TGSMITSVAKNLTGNINNGTYALGACLLVSCVLILAIPKRLLDNRADERE

Sequences:

>Translated_450_residues
MPILTETAASAAPVDETEERVYRKVLRRVLPLLLLCYVVAYLDRVNVGFAKLQMLDSLGLSDTIYAVGASIFFWGYFLFE
IPSNLLLHRYGARFWIARIMITWGIVSSSLAFIAPLARFFHVEASTMFYILRFLLGACEAGFFPGVILYMNYWFPARRQS
TAMSGFLIAIPVSLTLGGIVSGWLMENTHGLLGLGGWQWMLLLEGIPSILVAFVVLAFMGDGIASAKWLSASEKALLQRN
LEQEGTRKTHSIGAAFRNPHVWLLTFILLTFNTGFYGLAFWLPSIIRASGVQSPLSIGLLTAIPYLSAVVAMLWNAAHSR
RTGERRLHAAIPAGIGGVGLMLSAFFASNVPLSILFLTISTCAILGLMPIYWTFPGQILAGTAAAAGIALINSIGNLSGF
TGSMITSVAKNLTGNINNGTYALGACLLVSCVLILAIPKRLLDNRADERE
>Mature_449_residues
PILTETAASAAPVDETEERVYRKVLRRVLPLLLLCYVVAYLDRVNVGFAKLQMLDSLGLSDTIYAVGASIFFWGYFLFEI
PSNLLLHRYGARFWIARIMITWGIVSSSLAFIAPLARFFHVEASTMFYILRFLLGACEAGFFPGVILYMNYWFPARRQST
AMSGFLIAIPVSLTLGGIVSGWLMENTHGLLGLGGWQWMLLLEGIPSILVAFVVLAFMGDGIASAKWLSASEKALLQRNL
EQEGTRKTHSIGAAFRNPHVWLLTFILLTFNTGFYGLAFWLPSIIRASGVQSPLSIGLLTAIPYLSAVVAMLWNAAHSRR
TGERRLHAAIPAGIGGVGLMLSAFFASNVPLSILFLTISTCAILGLMPIYWTFPGQILAGTAAAAGIALINSIGNLSGFT
GSMITSVAKNLTGNINNGTYALGACLLVSCVLILAIPKRLLDNRADERE

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=421, Percent_Identity=35.3919239904988, Blast_Score=248, Evalue=8e-67,
Organism=Escherichia coli, GI2367379, Length=467, Percent_Identity=24.8394004282655, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789152, Length=452, Percent_Identity=22.3451327433628, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789515, Length=307, Percent_Identity=24.1042345276873, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=208, Percent_Identity=24.5192307692308, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321698, Length=320, Percent_Identity=22.8125, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130135, Length=331, Percent_Identity=22.6586102719033, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24655271, Length=331, Percent_Identity=22.6586102719033, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48955; Mature: 48824

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILTETAASAAPVDETEERVYRKVLRRVLPLLLLCYVVAYLDRVNVGFAKLQMLDSLGL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
SDTIYAVGASIFFWGYFLFEIPSNLLLHRYGARFWIARIMITWGIVSSSLAFIAPLARFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVEASTMFYILRFLLGACEAGFFPGVILYMNYWFPARRQSTAMSGFLIAIPVSLTLGGIV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHCCCCEEEHHHHHHHHHH
SGWLMENTHGLLGLGGWQWMLLLEGIPSILVAFVVLAFMGDGIASAKWLSASEKALLQRN
HHHHHHCCCCCEECCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LEQEGTRKTHSIGAAFRNPHVWLLTFILLTFNTGFYGLAFWLPSIIRASGVQSPLSIGLL
HHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
TAIPYLSAVVAMLWNAAHSRRTGERRLHAAIPAGIGGVGLMLSAFFASNVPLSILFLTIS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
TCAILGLMPIYWTFPGQILAGTAAAAGIALINSIGNLSGFTGSMITSVAKNLTGNINNGT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
YALGACLLVSCVLILAIPKRLLDNRADERE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PILTETAASAAPVDETEERVYRKVLRRVLPLLLLCYVVAYLDRVNVGFAKLQMLDSLGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
SDTIYAVGASIFFWGYFLFEIPSNLLLHRYGARFWIARIMITWGIVSSSLAFIAPLARFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVEASTMFYILRFLLGACEAGFFPGVILYMNYWFPARRQSTAMSGFLIAIPVSLTLGGIV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHCCCCEEEHHHHHHHHHH
SGWLMENTHGLLGLGGWQWMLLLEGIPSILVAFVVLAFMGDGIASAKWLSASEKALLQRN
HHHHHHCCCCCEECCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LEQEGTRKTHSIGAAFRNPHVWLLTFILLTFNTGFYGLAFWLPSIIRASGVQSPLSIGLL
HHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
TAIPYLSAVVAMLWNAAHSRRTGERRLHAAIPAGIGGVGLMLSAFFASNVPLSILFLTIS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
TCAILGLMPIYWTFPGQILAGTAAAAGIALINSIGNLSGFTGSMITSVAKNLTGNINNGT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
YALGACLLVSCVLILAIPKRLLDNRADERE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]