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The map label for this gene is trpF [H]

Identifier: 189352657

GI number: 189352657

Start: 746788

End: 747495

Strand: Direct

Name: trpF [H]

Synonym: BMULJ_03888

Alternate gene names: 189352657

Gene position: 746788-747495 (Clockwise)

Preceding gene: 189352656

Following gene: 189352658

Centisome position: 30.2

GC content: 68.64

Gene sequence:

>708_bases
ATGAACGATCCCGTTTCCTCCCGCTCGCTCGCCGAGTCAGCCGAATCCGCCGTGCCGCCGCGCACGCGCATCAAGCTGTG
CGGGCTGTCGCGCCCGGACGACGTGCTGCATGCCGCCGCGCTCGGCGCCGACGCGATCGGCCTCGTGTTCTACGCGAAAA
GCCCGCGCGCGGTGACGATCGCGCAGGCGGCCGAGCTCGCGCGTCTCGCGCCGCCGTTCGTGTCGGTGGTCGGCTTGTTC
GTGAACGCGACGGCGGCCGAGATCGAAGCGGTCGTACGCGACGTGCCGCTCACGCTGCTGCAGTTTCACGGCGACGAAAC
GCCGGAGCAGTGCGATGCGCTCGGCCGGGCGGCGCGTCTGCCGTGGGTGCGCGCGGTGCGCGTCGGGCCCTCGACGCAGT
CGGCCGATTTGGTAGAATCGTCACTTCATTACTCGAAAGCGCGCGGCCTCCTGTTCGACACACTGGTGCCGGACTACGGC
GGCAGCGGCAAGGTCTTCGATTGGTCACTTATTCCCGCAGAGCTCGCGCGTCGGGCCGTTTTGAGTGGTGGCTTGAACGC
GCAAAACGTCGGTGACGCGATCCGCCAGCTGCGTCCATTCGCTGTCGATGTCTCGAGCGGCATCGAAGTGGAGGGCGCAA
AGGGCGTGAAGGATCACGCCCGAATGGCGGCGTTCGTGCGCGCGGTGCGCGACGCGGACGCCCGGTGA

Upstream 100 bases:

>100_bases
ATCTCGCGCACGTCGGCTACCCGGCGGAATTCGCCGTCCCGCCCGCGCAGCTCGGCAGCGTGCCGTGGAGCAGCGTCTGG
GCCGACCTGGACCCGCAACC

Downstream 100 bases:

>100_bases
TGCCAGCCGGTGCGACTTCCCACAGCGGGGCGCACCGACCGATCGAGAGTGACACATCATGTACAACCTTCCTGACGATC
GCGGCCACTTCGGCCCGTAT

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNDPVSSRSLAESAESAVPPRTRIKLCGLSRPDDVLHAAALGADAIGLVFYAKSPRAVTIAQAAELARLAPPFVSVVGLF
VNATAAEIEAVVRDVPLTLLQFHGDETPEQCDALGRAARLPWVRAVRVGPSTQSADLVESSLHYSKARGLLFDTLVPDYG
GSGKVFDWSLIPAELARRAVLSGGLNAQNVGDAIRQLRPFAVDVSSGIEVEGAKGVKDHARMAAFVRAVRDADAR

Sequences:

>Translated_235_residues
MNDPVSSRSLAESAESAVPPRTRIKLCGLSRPDDVLHAAALGADAIGLVFYAKSPRAVTIAQAAELARLAPPFVSVVGLF
VNATAAEIEAVVRDVPLTLLQFHGDETPEQCDALGRAARLPWVRAVRVGPSTQSADLVESSLHYSKARGLLFDTLVPDYG
GSGKVFDWSLIPAELARRAVLSGGLNAQNVGDAIRQLRPFAVDVSSGIEVEGAKGVKDHARMAAFVRAVRDADAR
>Mature_235_residues
MNDPVSSRSLAESAESAVPPRTRIKLCGLSRPDDVLHAAALGADAIGLVFYAKSPRAVTIAQAAELARLAPPFVSVVGLF
VNATAAEIEAVVRDVPLTLLQFHGDETPEQCDALGRAARLPWVRAVRVGPSTQSADLVESSLHYSKARGLLFDTLVPDYG
GSGKVFDWSLIPAELARRAVLSGGLNAQNVGDAIRQLRPFAVDVSSGIEVEGAKGVKDHARMAAFVRAVRDADAR

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=210, Percent_Identity=31.9047619047619, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320210, Length=222, Percent_Identity=28.8288288288288, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24846; Mature: 24846

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPVSSRSLAESAESAVPPRTRIKLCGLSRPDDVLHAAALGADAIGLVFYAKSPRAVTI
CCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEHH
AQAAELARLAPPFVSVVGLFVNATAAEIEAVVRDVPLTLLQFHGDETPEQCDALGRAARL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCC
PWVRAVRVGPSTQSADLVESSLHYSKARGLLFDTLVPDYGGSGKVFDWSLIPAELARRAV
CHHEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHH
LSGGLNAQNVGDAIRQLRPFAVDVSSGIEVEGAKGVKDHARMAAFVRAVRDADAR
HHCCCCHHHHHHHHHHHCCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDPVSSRSLAESAESAVPPRTRIKLCGLSRPDDVLHAAALGADAIGLVFYAKSPRAVTI
CCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEHH
AQAAELARLAPPFVSVVGLFVNATAAEIEAVVRDVPLTLLQFHGDETPEQCDALGRAARL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCC
PWVRAVRVGPSTQSADLVESSLHYSKARGLLFDTLVPDYGGSGKVFDWSLIPAELARRAV
CHHEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHH
LSGGLNAQNVGDAIRQLRPFAVDVSSGIEVEGAKGVKDHARMAAFVRAVRDADAR
HHCCCCHHHHHHHHHHHCCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA