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The map label for this gene is ywqM [H]

Identifier: 189352527

GI number: 189352527

Start: 590489

End: 591412

Strand: Reverse

Name: ywqM [H]

Synonym: BMULJ_03755

Alternate gene names: 189352527

Gene position: 591412-590489 (Counterclockwise)

Preceding gene: 189352541

Following gene: 189352526

Centisome position: 23.91

GC content: 55.52

Gene sequence:

>924_bases
ATGAACACCCGTTTTCTCGAAACGTTCGTGTGGCTGGCGACACTGAAAAGCTTCCGGCTGACGGCAGACAAGCTGCACGC
GACACAAGGCGCGGTCTCGAGCCGCATTGCCAGCCTTGAACAGGATCTCGGTGTACGTCTGTTCGACCGCGGGTCAAAGG
AAGTCACGCTGACGCGCGATGGCAGCAAGGCACTGAAATACGCCGAACGCATCCTGTCGCTGGCGGAAGAAATGCGTAGC
GATCTGGGGGATCCAGACCGTGTATCAGGAATCGTGCGGATCGGCGTGATCGAGTCCATCGTCCATAGCTGGCTGTCCGG
GCTCATCACACGGCTTGGCAGAGAATTTCCAAACCTAACTATTGAGTTGACGAGCGATACGTCGCTCAAGTTGCGCGAAC
AGTTTCTCGCAGGATTGCTTGATATCATCCTACAGACAGACGTCCTGGCGGTCGAGCACGTTTCTAACGTTGAACTTGGG
AAACTCTCCATGTCGTGGGTCTCGAGCCCGAGCCTGGGACTTTCCGGAGAAGCACTTGAAGACACGGATCTCGCCGCATT
CCCAATCGTAAGCTTTTCGCGCGGATCGGGCCCACACCGCTCACTTGAAAACTATTTTCGAAACGTACCTTCCGGTCCCC
CGAAAATTAACTGTGTCACGTCGGTCGCAGCCATCATCAAGCTAACGGTTGACGGGTTTGGCATAGCGGTACTTCCCCGA
GCGATCATCCGACCAGAATTGGAGAACGGTCAACTAGCGCTGTTGAACGTTTCACGCGATTTCCCAGATCTCGAACTGGT
GGGTTCCTACCGAGCCGGCGTCGATAGCCTTTTGATAGAACGGATCGCCTCCATGAGTCAGGAAACAGCCCGTGAATTTG
CCCGAAAATCGGGCCGCGATGTTGCCACGTTCGGCGCTTCATGA

Upstream 100 bases:

>100_bases
GATGGAAAACCTGCGTTCCAATGGCCTAGCCGCACCGCTTGCTTGTCTTCATCCGCAGGCAATAGACTGATGACCCGACC
TCGTCAAAAGTGGTACCTCA

Downstream 100 bases:

>100_bases
AGCTCTACTATGTAGGTCCCGCTACTCGCTTATATGCAAAGAAACTAAAGAAATCACGAAACAAGAATTAAAGGGATCTA
ATCGGCTCCGAATAAAAAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNTRFLETFVWLATLKSFRLTADKLHATQGAVSSRIASLEQDLGVRLFDRGSKEVTLTRDGSKALKYAERILSLAEEMRS
DLGDPDRVSGIVRIGVIESIVHSWLSGLITRLGREFPNLTIELTSDTSLKLREQFLAGLLDIILQTDVLAVEHVSNVELG
KLSMSWVSSPSLGLSGEALEDTDLAAFPIVSFSRGSGPHRSLENYFRNVPSGPPKINCVTSVAAIIKLTVDGFGIAVLPR
AIIRPELENGQLALLNVSRDFPDLELVGSYRAGVDSLLIERIASMSQETAREFARKSGRDVATFGAS

Sequences:

>Translated_307_residues
MNTRFLETFVWLATLKSFRLTADKLHATQGAVSSRIASLEQDLGVRLFDRGSKEVTLTRDGSKALKYAERILSLAEEMRS
DLGDPDRVSGIVRIGVIESIVHSWLSGLITRLGREFPNLTIELTSDTSLKLREQFLAGLLDIILQTDVLAVEHVSNVELG
KLSMSWVSSPSLGLSGEALEDTDLAAFPIVSFSRGSGPHRSLENYFRNVPSGPPKINCVTSVAAIIKLTVDGFGIAVLPR
AIIRPELENGQLALLNVSRDFPDLELVGSYRAGVDSLLIERIASMSQETAREFARKSGRDVATFGAS
>Mature_307_residues
MNTRFLETFVWLATLKSFRLTADKLHATQGAVSSRIASLEQDLGVRLFDRGSKEVTLTRDGSKALKYAERILSLAEEMRS
DLGDPDRVSGIVRIGVIESIVHSWLSGLITRLGREFPNLTIELTSDTSLKLREQFLAGLLDIILQTDVLAVEHVSNVELG
KLSMSWVSSPSLGLSGEALEDTDLAAFPIVSFSRGSGPHRSLENYFRNVPSGPPKINCVTSVAAIIKLTVDGFGIAVLPR
AIIRPELENGQLALLNVSRDFPDLELVGSYRAGVDSLLIERIASMSQETAREFARKSGRDVATFGAS

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=27.9310344827586, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787806, Length=243, Percent_Identity=23.0452674897119, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=27.5409836065574, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=247, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787128, Length=158, Percent_Identity=31.6455696202532, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=296, Percent_Identity=26.6891891891892, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=178, Percent_Identity=31.4606741573034, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693105, Length=236, Percent_Identity=23.728813559322, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=30.0699300699301, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=261, Percent_Identity=27.2030651340996, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787530, Length=232, Percent_Identity=23.7068965517241, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786713, Length=274, Percent_Identity=28.1021897810219, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33485; Mature: 33485

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRFLETFVWLATLKSFRLTADKLHATQGAVSSRIASLEQDLGVRLFDRGSKEVTLTRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECC
GSKALKYAERILSLAEEMRSDLGDPDRVSGIVRIGVIESIVHSWLSGLITRLGREFPNLT
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IELTSDTSLKLREQFLAGLLDIILQTDVLAVEHVSNVELGKLSMSWVSSPSLGLSGEALE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCCCCCCCCCC
DTDLAAFPIVSFSRGSGPHRSLENYFRNVPSGPPKINCVTSVAAIIKLTVDGFGIAVLPR
CCCCCHHCCEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
AIIRPELENGQLALLNVSRDFPDLELVGSYRAGVDSLLIERIASMSQETAREFARKSGRD
HHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VATFGAS
CCCCCCC
>Mature Secondary Structure
MNTRFLETFVWLATLKSFRLTADKLHATQGAVSSRIASLEQDLGVRLFDRGSKEVTLTRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECC
GSKALKYAERILSLAEEMRSDLGDPDRVSGIVRIGVIESIVHSWLSGLITRLGREFPNLT
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IELTSDTSLKLREQFLAGLLDIILQTDVLAVEHVSNVELGKLSMSWVSSPSLGLSGEALE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCCCCCCCCCC
DTDLAAFPIVSFSRGSGPHRSLENYFRNVPSGPPKINCVTSVAAIIKLTVDGFGIAVLPR
CCCCCHHCCEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
AIIRPELENGQLALLNVSRDFPDLELVGSYRAGVDSLLIERIASMSQETAREFARKSGRD
HHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VATFGAS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]