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The map label for this gene is ycjZ [C]

Identifier: 189352503

GI number: 189352503

Start: 559660

End: 560562

Strand: Direct

Name: ycjZ [C]

Synonym: BMULJ_03725

Alternate gene names: 189352503

Gene position: 559660-560562 (Clockwise)

Preceding gene: 189352500

Following gene: 189352504

Centisome position: 22.63

GC content: 56.92

Gene sequence:

>903_bases
TTGAAGGAGGATTTCAACGATCTGGTCGGTTTCATGACTGTAGCGCGCGAACGCAATTTCACGCGCGCGGCGGCGCAAAT
GGGCGTCTCGCAATCCGCTCTTAGCCGCACAGTGGCAGGACTCGAAAGACGAATGGGCCTGCAGCTTCTAACGCGCACGA
CCCGCAGCGTCTCCCTAACCGAGGCCGGTGATAGGCTACTGTCAGCGATAGCGCCACGTTTCGAAGAAATCGAGGCGGAA
GTCGACTCACTGCGCGCGATGACGAACCAGCCAAGCGGGACCGTGCGAATTACAACCACAGACTACGCCGCTAAGTCATA
TGTCTGGCCACGGTTGCAATCCTTGCTGCGTCAGTATCCTGAGCTGAAGATCGAACTGGTCAACGACTATGGGCTGTCTG
ACATCGTTGCGGATCGATACGACATCGGCGTACGGTTAGGCGATCAGGTGGCCAAAGATATGGTTGCAGTGCGCATTGCC
CCCGACATGACGATGACGGTCGTCGGCTCGCCGAGCTACCTGCAGTCAAAGCCTCACGCCAGGACGCCGCAAGACTTGAC
GCTGCACAACTGCATCAACCTTCGCTTGCCGACGCGGGAATCGCTGCTTCCCTGGGAATTGCGCAAAGGCCGGCGAGAAC
TAAAGGTGCGGGTTGAAGGGCAACTCACGTTCAACAATGTATACCAGATGGTCGAGGCAGCGCTCGGCGGCTTTGGGCTT
GCATACGTACCCAAGGACCTCGTTGAGGATAAAGTACGTGCTGGCAGGTTGTGCTGGGTGCTTGAAGACTGGTATCCCAC
GTTCGTTGGACACCATGCTTATTATCCGAATCGACGTAAATCGTCGCGGGCGGTCGAACTTGTAATCGAAGCGCTGAAGA
CGGGTTATCAACGCAAGGCCTAG

Upstream 100 bases:

>100_bases
AGTGGTTGAGGGCAGAGTGCCACATGACGATAATCTAACTGCTGGTCATTCATGCGACAAGATGGCAATATCGGCATGCC
CTTATGCATGGGAGCATGAA

Downstream 100 bases:

>100_bases
CCTCGGCAATAATGGAGGAGCAGGAGCGGACCGTTGGACGGCAACGGCGCGGGACGCACGCCTGGCTATGGAGAGGTTTG
GGACGGCGAGACAAGTACGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKEDFNDLVGFMTVARERNFTRAAAQMGVSQSALSRTVAGLERRMGLQLLTRTTRSVSLTEAGDRLLSAIAPRFEEIEAE
VDSLRAMTNQPSGTVRITTTDYAAKSYVWPRLQSLLRQYPELKIELVNDYGLSDIVADRYDIGVRLGDQVAKDMVAVRIA
PDMTMTVVGSPSYLQSKPHARTPQDLTLHNCINLRLPTRESLLPWELRKGRRELKVRVEGQLTFNNVYQMVEAALGGFGL
AYVPKDLVEDKVRAGRLCWVLEDWYPTFVGHHAYYPNRRKSSRAVELVIEALKTGYQRKA

Sequences:

>Translated_300_residues
MKEDFNDLVGFMTVARERNFTRAAAQMGVSQSALSRTVAGLERRMGLQLLTRTTRSVSLTEAGDRLLSAIAPRFEEIEAE
VDSLRAMTNQPSGTVRITTTDYAAKSYVWPRLQSLLRQYPELKIELVNDYGLSDIVADRYDIGVRLGDQVAKDMVAVRIA
PDMTMTVVGSPSYLQSKPHARTPQDLTLHNCINLRLPTRESLLPWELRKGRRELKVRVEGQLTFNNVYQMVEAALGGFGL
AYVPKDLVEDKVRAGRLCWVLEDWYPTFVGHHAYYPNRRKSSRAVELVIEALKTGYQRKA
>Mature_300_residues
MKEDFNDLVGFMTVARERNFTRAAAQMGVSQSALSRTVAGLERRMGLQLLTRTTRSVSLTEAGDRLLSAIAPRFEEIEAE
VDSLRAMTNQPSGTVRITTTDYAAKSYVWPRLQSLLRQYPELKIELVNDYGLSDIVADRYDIGVRLGDQVAKDMVAVRIA
PDMTMTVVGSPSYLQSKPHARTPQDLTLHNCINLRLPTRESLLPWELRKGRRELKVRVEGQLTFNNVYQMVEAALGGFGL
AYVPKDLVEDKVRAGRLCWVLEDWYPTFVGHHAYYPNRRKSSRAVELVIEALKTGYQRKA

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=46.5753424657534, Blast_Score=284, Evalue=5e-78,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=36.271186440678, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI145693193, Length=286, Percent_Identity=30.7692307692308, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=27.3333333333333, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=27.9863481228669, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789440, Length=261, Percent_Identity=26.8199233716475, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789639, Length=285, Percent_Identity=29.1228070175439, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789173, Length=271, Percent_Identity=26.1992619926199, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786448, Length=288, Percent_Identity=23.6111111111111, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788706, Length=269, Percent_Identity=23.7918215613383, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=126, Percent_Identity=34.1269841269841, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI145693105, Length=151, Percent_Identity=23.841059602649, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790011, Length=306, Percent_Identity=22.8758169934641, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI157672245, Length=162, Percent_Identity=25.3086419753086, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790208, Length=255, Percent_Identity=23.1372549019608, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33952; Mature: 33952

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDFNDLVGFMTVARERNFTRAAAQMGVSQSALSRTVAGLERRMGLQLLTRTTRSVSLT
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEHH
EAGDRLLSAIAPRFEEIEAEVDSLRAMTNQPSGTVRITTTDYAAKSYVWPRLQSLLRQYP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCC
ELKIELVNDYGLSDIVADRYDIGVRLGDQVAKDMVAVRIAPDMTMTVVGSPSYLQSKPHA
CEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCEEEEECCCHHHCCCCCC
RTPQDLTLHNCINLRLPTRESLLPWELRKGRRELKVRVEGQLTFNNVYQMVEAALGGFGL
CCCCCCCHHHEEEEECCCCCCCCCHHHHCCCEEEEEEEEEEEEHHHHHHHHHHHHCCCCH
AYVPKDLVEDKVRAGRLCWVLEDWYPTFVGHHAYYPNRRKSSRAVELVIEALKTGYQRKA
HHCCHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKEDFNDLVGFMTVARERNFTRAAAQMGVSQSALSRTVAGLERRMGLQLLTRTTRSVSLT
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEHH
EAGDRLLSAIAPRFEEIEAEVDSLRAMTNQPSGTVRITTTDYAAKSYVWPRLQSLLRQYP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCC
ELKIELVNDYGLSDIVADRYDIGVRLGDQVAKDMVAVRIAPDMTMTVVGSPSYLQSKPHA
CEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCEEEEECCCHHHCCCCCC
RTPQDLTLHNCINLRLPTRESLLPWELRKGRRELKVRVEGQLTFNNVYQMVEAALGGFGL
CCCCCCCHHHEEEEECCCCCCCCCHHHHCCCEEEEEEEEEEEEHHHHHHHHHHHHCCCCH
AYVPKDLVEDKVRAGRLCWVLEDWYPTFVGHHAYYPNRRKSSRAVELVIEALKTGYQRKA
HHCCHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]